-
1
-
-
84881621285
-
- secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells
-
- secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells. Am J Physiol Cell Physiol 305: C447-C456, 2013.
-
(2013)
Am J Physiol Cell Physiol
, vol.305
-
-
Ao, M.1
Sarathy, J.2
Domingue, J.3
Alrefai, W.4
Rao, M.5
-
2
-
-
36148930617
-
Liquid movement across the surface epithelium of large airways
-
Chambers L, Rollins B, Tarran R. Liquid movement across the surface epithelium of large airways. Respir Physiol Neurobiol 159: 256-270, 2007.
-
(2007)
Respir Physiol Neurobiol
, vol.159
, pp. 256-270
-
-
Chambers, L.1
Rollins, B.2
Tarran, R.3
-
3
-
-
79960982538
-
Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins
-
Chen X, Oshima T, Tomita T, Fukui H, Watari J, Matsumoto T, Miwa H. Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins. Am J Physiol Gastrointest Liver Physiol 301: G203-G209, 2011.
-
(2011)
Am J Physiol Gastrointest Liver Physiol
, vol.301
-
-
Chen, X.1
Oshima, T.2
Tomita, T.3
Fukui, H.4
Watari, J.5
Matsumoto, T.6
Miwa, H.7
-
4
-
-
0037304235
-
Bile salts potentiate adenylyl cyclase activity and cAMP-regulated secretion in human gallbladder epithelium
-
Chignard N, Mergey M, Veissière D, Poupon R, Capeau J, Parc R, Paul A, Housset C. Bile salts potentiate adenylyl cyclase activity and cAMP-regulated secretion in human gallbladder epithelium. Am J Physiol Gastrointest Liver Physiol 284: G205-G212, 2003.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Chignard, N.1
Mergey, M.2
Veissière, D.3
Poupon, R.4
Capeau, J.5
Parc, R.6
Paul, A.7
Housset, C.8
-
5
-
-
20944434567
-
Bile acid aspiration and the development of bronchiolitis obliterans after lung transplantation
-
D'Ovidio F, Mura M, Waddell TK, Hutcheon MA, Singer LG, Hadjiliadis D, Chaparro C, Gutierrez C, Pierre A, Darling G, Liu M, Keshavjee S. Bile acid aspiration and the development of bronchiolitis obliterans after lung transplantation. J Thorac Cardiovasc Surg 129: 1144-1152, 2005.
-
(2005)
J Thorac Cardiovasc Surg
, vol.129
, pp. 1144-1152
-
-
D'Ovidio, F.1
Mura, M.2
Waddell, T.K.3
Hutcheon, M.A.4
Singer, L.G.5
Hadjiliadis, D.6
Chaparro, C.7
Gutierrez, C.8
Pierre, A.9
Darling, G.10
Liu, M.11
Keshavjee, S.12
-
6
-
-
59849111265
-
Bile acids cause secretory phospholipase A2 activity enhancement, revertible by exogenous surfactant administration
-
De Luca D, Minucci A, Zecca E, Piastra M, Pietrini D, Carnielli V, Zuppi C, Tridente A, Conti G, Capoluongo E. Bile acids cause secretory phospholipase A2 activity enhancement, revertible by exogenous surfactant administration. Intensive Care Med 35: 321-326, 2009.
-
(2009)
Intensive Care Med
, vol.35
, pp. 321-326
-
-
De Luca, D.1
Minucci, A.2
Zecca, E.3
Piastra, M.4
Pietrini, D.5
Carnielli, V.6
Zuppi, C.7
Tridente, A.8
Conti, G.9
Capoluongo, E.10
-
7
-
-
0027366949
-
Taurodeoxycholate activates potassium and chloride conductances via an IP3-mediated release of calcium from intracellular stores in a colonic cell line (T84)
-
Devor D, Sekar M, Frizzell R, Duffey M. Taurodeoxycholate activates potassium and chloride conductances via an IP3-mediated release of calcium from intracellular stores in a colonic cell line (T84). J Clin Invest 92: 2173-2181, 1993.
-
(1993)
J Clin Invest
, vol.92
, pp. 2173-2181
-
-
Devor, D.1
Sekar, M.2
Frizzell, R.3
Duffey, M.4
-
9
-
-
84861880073
-
Bile acids acutely stimulate insulin secretion of mouse β-cells via farnesoid X receptor activation and K(ATP) channel inhibition
-
Düfer M, Hörth K, Wagner R, Schittenhelm B, Prowald S, Wagner T, Oberwinkler J, Lukowski R, Gonzalez F, Krippeit-Drews P, Drews G. Bile acids acutely stimulate insulin secretion of mouse β-cells via farnesoid X receptor activation and K(ATP) channel inhibition. Diabetes 61: 1479-1489, 2012.
-
(2012)
Diabetes
, vol.61
, pp. 1479-1489
-
-
Düfer, M.1
Hörth, K.2
Wagner, R.3
Schittenhelm, B.4
Prowald, S.5
Wagner, T.6
Oberwinkler, J.7
Lukowski, R.8
Gonzalez, F.9
Krippeit-Drews, P.10
Drews, G.11
-
10
-
-
35648934624
-
Ursodeoxycholic acid stimulates cholangiocyte fluid secretion in mice via CFTR-dependent ATP secretion
-
Fiorotto R, Spirlμ C, Fabris L, Cadamuro M, Okolicsanyi L, Strazzabosco M. Ursodeoxycholic acid stimulates cholangiocyte fluid secretion in mice via CFTR-dependent ATP secretion. Gastroenterology 133: 1603-1613, 2007.
-
(2007)
Gastroenterology
, vol.133
, pp. 1603-1613
-
-
Fiorotto, R.1
Spirl, C.2
Fabris, L.3
Cadamuro, M.4
Okolicsanyi, L.5
Strazzabosco, M.6
-
11
-
-
0035149523
-
Cyclic AMP increases cell surface expression of functional Na, K-ATPase units in mammalian cortical collecting duct principal cells
-
Gonin S, Deschênes G, Roger F, Bens M, Martin P, Carpentier J, Vandewalle A, Doucet A, Féraille E. Cyclic AMP increases cell surface expression of functional Na, K-ATPase units in mammalian cortical collecting duct principal cells. Mol Biol Cell 12: 255-264, 2001.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 255-264
-
-
Gonin, S.1
Deschênes, G.2
Roger, F.3
Bens, M.4
Martin, P.5
Carpentier, J.6
Vandewalle, A.7
Doucet, A.8
Féraille, E.9
-
12
-
-
0037404448
-
Physiological modulation of CFTR activity by AMP-activated protein kinase in polarized T84 cells
-
Hallows KR, Kobinger GP, Wilson JM, Witters LA, Foskett JK. Physiological modulation of CFTR activity by AMP-activated protein kinase in polarized T84 cells. Am J Physiol Cell Physiol 284: C1297-C1308, 2003.
-
(2003)
Am J Physiol Cell Physiol
, vol.284
-
-
Hallows, K.R.1
Kobinger, G.P.2
Wilson, J.M.3
Witters, L.A.4
Foskett, J.K.5
-
13
-
-
80052397500
-
Screening of siRNA nanoparticles for delivery to airway epithelial cells using high-content analysis
-
Hibbitts A, Lieggi N, McCabe O, Thomas W, Barlow J, O'Brien F, Cryan S. Screening of siRNA nanoparticles for delivery to airway epithelial cells using high-content analysis. Ther Deliv 2: 987-999, 2011.
-
(2011)
Ther Deliv
, vol.2
, pp. 987-999
-
-
Hibbitts, A.1
Lieggi, N.2
McCabe, O.3
Thomas, W.4
Barlow, J.5
O'Brien, F.6
Cryan, S.7
-
14
-
-
0030931391
-
Raised bile acid concentrations in SIDS lungs at necropsy
-
Hills B, Chen Y, Masters I, Hills Y. Raised bile acid concentrations in SIDS lungs at necropsy. Arch Dis Child 77: 120-123, 1997.
-
(1997)
Arch Dis Child
, vol.77
, pp. 120-123
-
-
Hills, B.1
Chen, Y.2
Masters, I.3
Hills, Y.4
-
15
-
-
0035132659
-
Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH
-
Jayaraman S, Song Y, Vetrivel L, Shankar L, Verkman A. Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH. J Clin Invest 107: 317-324, 2001.
-
(2001)
J Clin Invest
, vol.107
, pp. 317-324
-
-
Jayaraman, S.1
Song, Y.2
Vetrivel, L.3
Shankar, L.4
Verkman, A.5
-
16
-
-
0025177058
-
Surfactant therapy for pulmonary edema due to intratracheally injected bile acid
-
Kaneko T, Sato T, Katsuya H, Miyauchi Y. Surfactant therapy for pulmonary edema due to intratracheally injected bile acid. Crit Care Med 18: 77-83, 1990.
-
(1990)
Crit Care Med
, vol.18
, pp. 77-83
-
-
Kaneko, T.1
Sato, T.2
Katsuya, H.3
Miyauchi, Y.4
-
17
-
-
0003269455
-
A G protein-coupled receptor responsive to bile acids
-
Kawamata Y, Fujii R, Hosoya M, Harada M, Yoshida H, Miwa M, Fukusumi S, Habata Y, Itoh T, Shintani Y, Hinuma S, Fujisawa Y, Fujino M. A G protein-coupled receptor responsive to bile acids. J Biol Chem 278: 9435-9440, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 9435-9440
-
-
Kawamata, Y.1
Fujii, R.2
Hosoya, M.3
Harada, M.4
Yoshida, H.5
Miwa, M.6
Fukusumi, S.7
Habata, Y.8
Itoh, T.9
Shintani, Y.10
Hinuma, S.11
Fujisawa, Y.12
Fujino, M.13
-
18
-
-
70349509723
-
Bile acids in regulation of intestinal physiology
-
Keating N, Keely S. Bile acids in regulation of intestinal physiology. Curr Gastroenterol Rep 11: 375-382, 2009.
-
(2009)
Curr Gastroenterol Rep
, vol.11
, pp. 375-382
-
-
Keating, N.1
Keely, S.2
-
19
-
-
84906908149
-
W1663 farnesoid X receptor activation downregulates chloride secretion in colonic epithelial cells
-
Keating N, Keely S. W1663 farnesoid X receptor activation downregulates chloride secretion in colonic epithelial cells. Gastroenterology 136: a172-a173, 2009.
-
(2009)
Gastroenterology
, vol.136
-
-
Keating, N.1
Keely, S.2
-
20
-
-
77953339910
-
Missing link identified: GpBAR1 is a neuronal bile acid receptor
-
Keely SJ. Missing link identified: GpBAR1 is a neuronal bile acid receptor. Neurogastroenterol Motil 22: 711-717, 2010.
-
(2010)
Neurogastroenterol Motil
, vol.22
, pp. 711-717
-
-
Keely, S.J.1
-
21
-
-
33846162297
-
Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships
-
Keely SJ, Scharl MM, Bertelsen LS, Hagey LR, Barrett KE, Hofmann AF. Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships. Am J Physiol Gastrointest Liver Physiol 292: G290-G297, 2007.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.292
-
-
Keely, S.J.1
Scharl, M.M.2
Bertelsen, L.S.3
Hagey, L.R.4
Barrett, K.E.5
Hofmann, A.F.6
-
22
-
-
70349255713
-
The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders
-
Keitel V, Cupisti K, Ullmer C, Knoefel W, Kubitz R, Häussinger D. The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders. Hepatology 50: 861-870, 2009.
-
(2009)
Hepatology
, vol.50
, pp. 861-870
-
-
Keitel, V.1
Cupisti, K.2
Ullmer, C.3
Knoefel, W.4
Kubitz, R.5
Häussinger, D.6
-
23
-
-
84877000653
-
Ursodeoxycholic acid attenuates colonic epithelial secretory function
-
Kelly O, Mroz M, Ward J, Colliva C, Scharl M, Pellicciari R, Gilmer J, Fallon P, Hofmann A, Roda A, Murray F, Keely S. Ursodeoxycholic acid attenuates colonic epithelial secretory function. J Physiol 1: 2307-2318, 2013.
-
(2013)
J Physiol
, vol.1
, pp. 2307-2318
-
-
Kelly, O.1
Mroz, M.2
Ward, J.3
Colliva, C.4
Scharl, M.5
Pellicciari, R.6
Gilmer, J.7
Fallon, P.8
Hofmann, A.9
Roda, A.10
Murray, F.11
Keely, S.12
-
24
-
-
0020605860
-
Basolateral potassium channel in turtle colon. Evidence for single-file ion flow
-
Kirk K, Dawson D. Basolateral potassium channel in turtle colon. Evidence for single-file ion flow. J Gen Physiol 82: 297-329, 1983.
-
(1983)
J Gen Physiol
, vol.82
, pp. 297-329
-
-
Kirk, K.1
Dawson, D.2
-
25
-
-
84879297569
-
Protein kinase A-Iα regulates Na, K-ATPase endocytosis in alveolar epithelial cells exposed to high CO(2) concentrations
-
Lecuona E, Sun H, Chen J, Trejo H, Baker M, Sznajder J. Protein kinase A-Iα regulates Na, K-ATPase endocytosis in alveolar epithelial cells exposed to high CO(2) concentrations. Am J Respir Cell Mol Biol 48: 626-634, 2013.
-
(2013)
Am J Respir Cell Mol Biol
, vol.48
, pp. 626-634
-
-
Lecuona, E.1
Sun, H.2
Chen, J.3
Trejo, H.4
Baker, M.5
Sznajder, J.6
-
26
-
-
14844304328
-
Regulation of complement C3 expression by the bile acid receptor FXR
-
Li J, Pircher P, Schulman I, Westin S. Regulation of complement C3 expression by the bile acid receptor FXR. J Biol Chem 280: 7427-7434, 2004.
-
(2004)
J Biol Chem
, vol.280
, pp. 7427-7434
-
-
Li, J.1
Pircher, P.2
Schulman, I.3
Westin, S.4
-
27
-
-
0036432845
-
Identification of membrane-type receptor for bile acids (M-BAR)
-
Maruyama T, Miyamoto Y, Nakamura T, Tamai Y, Okada H, Sugiyama E, Itadani H, Tanaka K. Identification of membrane-type receptor for bile acids (M-BAR). Biochem Biophys Res Commun 298: 714-719, 2002.
-
(2002)
Biochem Biophys Res Commun
, vol.298
, pp. 714-719
-
-
Maruyama, T.1
Miyamoto, Y.2
Nakamura, T.3
Tamai, Y.4
Okada, H.5
Sugiyama, E.6
Itadani, H.7
Tanaka, K.8
-
28
-
-
84898011280
-
Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo
-
Mroz M, Keating N, Ward J, Sarker R, Amu S, Aviello G, Donowitz M, Fallon P, Keely S. Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo. Gut 63: 808-817, 2013.
-
(2013)
Gut
, vol.63
, pp. 808-817
-
-
Mroz, M.1
Keating, N.2
Ward, J.3
Sarker, R.4
Amu, S.5
Aviello, G.6
Donowitz, M.7
Fallon, P.8
Keely, S.9
-
29
-
-
84859710006
-
Epidermal growth factor chronically upregulates Ca(2+)-dependent Cl(-) conductance and TMEM16A expression in intestinal epithelial cells
-
Mroz M, Keely S. Epidermal growth factor chronically upregulates Ca(2+)-dependent Cl(-) conductance and TMEM16A expression in intestinal epithelial cells. J Physiol 590: 1907-1920, 2012.
-
(2012)
J Physiol
, vol.590
, pp. 1907-1920
-
-
Mroz, M.1
Keely, S.2
-
30
-
-
84862017668
-
Bile acids in sputum and increased airway inflammation in patients with cystic fibrosis
-
Pauwels A, Decraene A, Blondeau K, Mertens V, Farre R, Proesmans M, Van Bleyenbergh P, Sifrim D, Dupont LJ. Bile acids in sputum and increased airway inflammation in patients with cystic fibrosis. Chest 141: 1568-1574, 2012.
-
(2012)
Chest
, vol.141
, pp. 1568-1574
-
-
Pauwels, A.1
Decraene, A.2
Blondeau, K.3
Mertens, V.4
Farre, R.5
Proesmans, M.6
Van Bleyenbergh, P.7
Sifrim, D.8
Dupont, L.J.9
-
31
-
-
36348944476
-
Exposure of airway epithelium to bile acids associated with gastroesophageal reflux symptoms: A relation to transforming growth factor-beta1 production and fibroblast proliferation
-
Perng D, Chang K, Su K, Wu Y, Wu M, Hsu W, Tsai C, Lee Y. Exposure of airway epithelium to bile acids associated with gastroesophageal reflux symptoms: a relation to transforming growth factor-beta1 production and fibroblast proliferation. Chest 132: 1548-1556, 2007.
-
(2007)
Chest
, vol.132
, pp. 1548-1556
-
-
Perng, D.1
Chang, K.2
Su, K.3
Wu, Y.4
Wu, M.5
Hsu, W.6
Tsai, C.7
Lee, Y.8
-
32
-
-
0023514972
-
Taurodeoxycholate and the developing rabbit distal colon: Absence of secretory effect
-
Potter G, Lester R, Burlingame S, Mitchell P, Schmidt K. Taurodeoxycholate and the developing rabbit distal colon: absence of secretory effect. Am J Physiol 253: G483-G488, 1987.
-
(1987)
Am J Physiol
, vol.253
-
-
Potter, G.1
Lester, R.2
Burlingame, S.3
Mitchell, P.4
Schmidt, K.5
-
33
-
-
84866847219
-
Respiratory pathogens adopt a chronic lifestyle in response to bile
-
Reen F, Woods D, Mooij M, Adams C, O'Gara F. Respiratory pathogens adopt a chronic lifestyle in response to bile. PLoS One 7: e45978, 2012.
-
(2012)
PLoS One
, vol.7
-
-
Reen, F.1
Woods, D.2
Mooij, M.3
Adams, C.4
O'Gara, F.5
-
34
-
-
84887263711
-
Gastro-oesophageal reflux and gastric aspiration in idiopathic pulmonary fibrosis patients
-
Savarino E, Carbone R, Marabotto E, Furnari M, Sconfienza L, Ghio M, Zentilin P, Savarino V. Gastro-oesophageal reflux and gastric aspiration in idiopathic pulmonary fibrosis patients. Eur Respir J 42: 1322-1331, 2013.
-
(2013)
Eur Respir J
, vol.42
, pp. 1322-1331
-
-
Savarino, E.1
Carbone, R.2
Marabotto, E.3
Furnari, M.4
Sconfienza, L.5
Ghio, M.6
Zentilin, P.7
Savarino, V.8
-
35
-
-
27144510923
-
Muscarinic receptor stimulation activates a Ca(2+)-dependent Cl(-) conductance in rat distal colon
-
Schultheiss G, Siefjediers A, Diener M. Muscarinic receptor stimulation activates a Ca(2+)-dependent Cl(-) conductance in rat distal colon. J Membr Biol 204: 117-127, 2005.
-
(2005)
J Membr Biol
, vol.204
, pp. 117-127
-
-
Schultheiss, G.1
Siefjediers, A.2
Diener, M.3
-
37
-
-
84879397766
-
Bile acids increase alveolar epithelial permeability via mitogenactivated protein kinase, cytosolic phospholipase A2, cyclooxygenase-2, prostaglandin E2 and junctional proteins
-
Su K, Wu Y, Chen C, Hung M, Hsiao Y, Tseng C, Chang S, Lee Y, Perng D. Bile acids increase alveolar epithelial permeability via mitogenactivated protein kinase, cytosolic phospholipase A2, cyclooxygenase-2, prostaglandin E2 and junctional proteins. Respirology 18: 848-856, 2013.
-
(2013)
Respirology
, vol.18
, pp. 848-856
-
-
Su, K.1
Wu, Y.2
Chen, C.3
Hung, M.4
Hsiao, Y.5
Tseng, C.6
Chang, S.7
Lee, Y.8
Perng, D.9
-
38
-
-
78651422390
-
Chronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors
-
Toumi F, Frankson M, Ward JB, Kelly OB, Mroz MS, Bertelsen LS, Keely SJ. Chronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors. Neurogastroenterol Motil 23: 178-186; e143, 2011.
-
(2011)
Neurogastroenterol Motil
, vol.23
-
-
Toumi, F.1
Frankson, M.2
Ward, J.B.3
Kelly, O.B.4
Mroz, M.S.5
Bertelsen, L.S.6
Keely, S.J.7
-
39
-
-
84880136128
-
The bile acid receptor, TGR5, regulates basal and cholinergic-induced secretory responses in rat colon
-
Ward J, Mroz M, Keely S. The bile acid receptor, TGR5, regulates basal and cholinergic-induced secretory responses in rat colon. Neurogastroenterol Motil 25: 708-711, 2013.
-
(2013)
Neurogastroenterol Motil
, vol.25
, pp. 708-711
-
-
Ward, J.1
Mroz, M.2
Keely, S.3
-
40
-
-
0025604533
-
Carbachol increases basolateral K+ conductance in T84 cells. Simultaneous measurements of cell [Ca] and gK explore calcium's role
-
Wong SM, Tesfaye A, DeBell MC, Chase HS Jr. Carbachol increases basolateral K+ conductance in T84 cells. Simultaneous measurements of cell [Ca] and gK explore calcium's role. J Gen Physiol 96: 1271-1285, 1990.
-
(1990)
J Gen Physiol
, vol.96
, pp. 1271-1285
-
-
Wong, S.M.1
Tesfaye, A.2
DeBell, M.C.3
Chase Jr., H.S.4
-
41
-
-
3042759727
-
Bile acid pneumonia: A "new" form of neonatal respiratory distress syndrome?
-
Zecca E, Costa S, Lauriola V, Vento G, Papacci P, Romagnoli C. Bile acid pneumonia: a "new" form of neonatal respiratory distress syndrome? Pediatrics 114: 269-272, 2004.
-
(2004)
Pediatrics
, vol.114
, pp. 269-272
-
-
Zecca, E.1
Costa, S.2
Lauriola, V.3
Vento, G.4
Papacci, P.5
Romagnoli, C.6
-
42
-
-
38049070222
-
Bile acid-induced lung injury in newborn infants: A bronchoalveolar lavage fluid study
-
Zecca E, De Luca D, Baroni S, Vento G, Tiberi E, Romagnoli C. Bile acid-induced lung injury in newborn infants: a bronchoalveolar lavage fluid study. Pediatrics 121: e146-e149, 2008.
-
(2008)
Pediatrics
, vol.121
-
-
Zecca, E.1
De Luca, D.2
Baroni, S.3
Vento, G.4
Tiberi, E.5
Romagnoli, C.6
-
43
-
-
84880323644
-
The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice
-
Zhou C, Shi Y, Li J, Zhang W, Wang Y, Liu Y, Liu J. The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice. Pak J Pharm Sci 26: 761-765, 2013.
-
(2013)
Pak J Pharm Sci
, vol.26
, pp. 761-765
-
-
Zhou, C.1
Shi, Y.2
Li, J.3
Zhang, W.4
Wang, Y.5
Liu, Y.6
Liu, J.7
-
44
-
-
73249142867
-
Discovery of 6alpha-ethyl-23(S)-methylcholic acid (SEMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity
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Pellicciari R, Gioiello A, Macchiarulo A, Thomas C, Rosatelli E, Natalini B, Sardella R, Pruzanski M, Roda A, Pastorini E, Schoonjans K, Auwerx J. Discovery of 6alpha-ethyl-23(S)-methylcholic acid (SEMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity. J Med Chem 52: 7958-7961, 2009.
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(2009)
J Med Chem
, vol.52
, pp. 7958-7961
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Pellicciari, R.1
Gioiello, A.2
Macchiarulo, A.3
Thomas, C.4
Rosatelli, E.5
Natalini, B.6
Sardella, R.7
Pruzanski, M.8
Roda, A.9
Pastorini, E.10
Schoonjans, K.11
Auwerx, J.12
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