Bile acids increase alveolar epithelial permeability via mitogen-activated protein kinase, cytosolic phospholipase A2, cyclooxygenase-2, prostaglandin E2 and junctional proteins

Respirology

Volumn 18, Issue 5, 2013, Pages 848-856

  Su, Kang Cheng ^a,b   Wu, Yu Chung ^a,b   Chen, Chun Sheng ^b   Hung, Ming Hui ^b   Hsiao, Yi Han ^b   Tseng, Ching Min ^b   Chang, Shi Chuan ^a,b   Lee, Yu Chin ^b   Perng, Diahn Warng ^b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

alveolar permeability; junctional protein; paracellular flux; prostaglandin E2; transepithelial electrical resistance

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CHENODEOXYCHOLIC ACID; CYCLOOXYGENASE 2; CYTOSOLIC PHOSPHOLIPASE A2; DEXAMETHASONE; MEPACRINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; OCCLUDIN; PROSTAGLANDIN E2; PROTEIN ZO1; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TIGHT JUNCTION PROTEIN; UVOMORULIN;

ACID ASPIRATION; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL VIABILITY; CONTROLLED STUDY; ELECTRIC RESISTANCE; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSEPITHELIAL ELECTRICAL RESISTANCE; UPREGULATION; WESTERN BLOTTING;

BILE ACIDS AND SALTS; CADHERINS; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; CHENODEOXYCHOLIC ACID; CYCLOOXYGENASE 2; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; OCCLUDIN; PHOSPHOLIPASES A2, CYTOSOLIC; PULMONARY ALVEOLI; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; TIGHT JUNCTION PROTEINS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84879397766     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/resp.12086     Document Type: Article

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