Bile acids cause secretory phospholipase A2 activity enhancement, revertible by exogenous surfactant administration

Intensive Care Medicine

Volumn 35, Issue 2, 2009, Pages 321-326

  De Luca, Daniele ^a   Minucci, Angelo ^a   Zecca, Enrico ^a   Piastra, Marco ^a   Pietrini, Domenico ^a   Carnielli, Virgilio P ^b,c   Zuppi, Cecilia ^a   Tridente, Ascanio ^d   Conti, Giorgio ^a   Capoluongo, Ettore D ^a  

^a FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^c GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^d PRINCE CHARLES HOSPITAL   (United Kingdom)

Author keywords

Bile acids; Infant; Lung injury; Neonate; Phospholipase A2; Surfactant

Indexed keywords

BILE ACID; PHOSPHOLIPID; PORACTANT; SECRETORY PHOSPHOLIPASE A2; SODIUM CHLORIDE; SURFACTANT; UREA;

ARTICLE; CLINICAL ARTICLE; DRUG METABOLISM; ENZYME ACTIVITY; EXTRACELLULAR SPACE; HUMAN; IN VITRO STUDY; INFANT; LUNG LAVAGE; NEONATAL RESPIRATORY DISTRESS SYNDROME; NEWBORN; PHOSPHOLIPID BLOOD LEVEL; PROTEIN INTERACTION; PULMONARY ASPIRATION; SUBSTITUTION THERAPY;

BILE ACIDS AND SALTS; BIOLOGICAL PRODUCTS; BRONCHOALVEOLAR LAVAGE FLUID; EXTRACELLULAR SPACE; HUMANS; INFANT, NEWBORN; LUNG INJURY; PHOSPHOLIPASES A2, SECRETORY; PHOSPHOLIPIDS; PULMONARY SURFACTANTS;

EID: 59849111265     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-008-1321-3     Document Type: Article

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