The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice

Pakistan Journal of Pharmaceutical Sciences

Volumn 26, Issue 4, 2013, Pages 761-765

  Zhou, Chuan ^a   Shi, Youfei ^a   Li, Jinlian ^b   Zhang, Wen ^a   Fu, Changqi ^a   Wang, Yanmin ^a   Liu, Yan ^a   Liu, Jianzhu ^a  

^a SHANDONG AGRICULTURAL UNIVERSITY   (China)

^b TAISHAN UNIVERSITY   (China)

Author keywords

Mice; Preventing; Pulmonary fibrosis; Taurochenodeoxycholic acid

Indexed keywords

BILE ACID; BLEOMYCIN; COMPLEMENTARY DNA; FXR ALPHA PROTEIN; GELATINASE A; GELATINASE B; PEPTIDES AND PROTEINS; RNA 18S; TAUROCHENODEOXYCHOLIC ACID; TGR5 PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HUMAN; LUNG FIBROSIS; LUNG INJURY; LUNG PARENCHYMA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT;

ANIMALS; FEMALE; LUNG; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; PULMONARY FIBROSIS; RECEPTORS, G-PROTEIN-COUPLED; STAINING AND LABELING; TAUROCHENODEOXYCHOLIC ACID; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84880323644     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Fiorucci S, Rizzo G, Antonelli E, Renga B, Mencarelli A, Riccardi L, Orlandi S, Pruzanski M, Morelli A and Pellicciari R (2005). A farnesoid x receptor-small heterodimer partner regulatory cascade modulates tissue metalloproteinase inhibitor-1 and matrix metalloprotease expression in hepatic stellate cells and promotes resolution of liver fibrosis. J. Pharmacol. Exp. Ther., 314(2): 584-595.
2. Gharaee-Kermani M, Ullenbruch M and Phan SH (2005). Animal models of pulmonary fibrosis. Methods Mol. Med., 117: 251-259.
3. Huang W, Ma K, Zhang J, Qatanani M, Cuvillier J, Liu J, Dong B, Huang X and Moore DD (2006). Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration. Science, 312(5771): 233-236.
4. Hylemon PB, Zhou H, Pandak WM, Ren S, Gil G and Dent P (2009). Bile acids as regulatory molecules. J. Lipid Res., 50(8): 1509-1520.
5. Jiang T, Wang XX, Scherzer P, Wilson P, Tallman J, Takahashi H, Li J, Iwahashi M, Sutherland E, Arend L and Levi M (2007). Farnesoid X receptor modulates renal lipid metabolism, fibrosis, and diabetic nephropathy. Diabetes, 56(10): 2485-2493.
6. Kamata H, Tasaka S, Inoue K, Miyamoto K, Nakano Y, Shinoda H, Kimizuka Y, Fujiwara H, Ishii M, Hasegawa N, Takamiya R, Fujishima S, Takano H and Ishizaka A (2011). Carbon black nanoparticles enhance bleomycin-induced lung inflammatory and fibrotic changes in mice. Exp. Biol. Med. (Maywood), 236(3): 315-324.
7. Katsuma S, Hirasawa A and Tsujimoto G (2005). Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1. Biochem. Biophys. Res. Commun., 329(1): 386-390.
8. Kawamata Y, Fujii R, Hosoya M, Harada M, Yoshida H, Miwa M, Fukusumi S, Habata Y, Itoh T, Shintani Y, Hinuma S, Fujisawa Y and Fujino M (2003). A G protein-coupled receptor responsive to bile acids. J. Biol. Chem., 278(11): 9435-9440.
9. Keitel V, Donner M, Winandy S, Kubitz R and Häussinger D(2008). Expression and function of the bile acid receptor TGR5 in Kupffer cells. Biochem. Biophys. Res. Commun., 372(1): 78-84.
10. Keitel V, Kubitz R and Häussinger D (2008). Endocrine and paracrine role of bile acids. World J. Gastroenterol., 14(37): 5620-5629.
11. Liu M, Mao W, Guan H, Li L, Wei B and Li P(2011). Effects of taurochenodeoxycholic acid on adjuvant arthritis in rats. Intl. Immunopharmacol., 11(12): 2150-2158.
12. Schote AB, Turner JD, Schiltz J and Muller CP (2007). Nuclear receptors in human immune cells: Expression and correlations. Mol. Immunol., 44(6): 1436-1445.
13. Shi Y, Li P and Li J (2007). Regulation effect of taurochenodeoxycholic acid immunologic function in mice. Chin. Pharmacological Bulletin, 23(7): 859-865.
14. Turner DJ, Alaish SM, Zou T, Rao JN, Wang JY and Strauch ED (2007). Bile Salts Induce Resistance to Apoptosis Through NF-?B-mediated XIAP Expression. Ann. Surg., 245(3): 415-425.
15. Vavassori P, Mencarelli A, Renga B, Distrutti E and Fiorucci S (2009). The bile acid receptor FXR is a modulator of intestinal innate immunity. J. Immunol., 183(10): 6251-6261.
16. Watanabe M, Houten SM, Mataki C, Christoffolete MA, Kim BW, Sato H, Messaddeq N, Harney JW, Ezaki O, Kodama T, Schoonjans K, Bianco AC and Auwerx J (2006). Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature, 439(7075): 484-489.