Genetic and molecular identification of three human TPP1 functions in telomerase action: Recruitment, activation, and homeostasis set point regulation

Genes and Development

Volumn 28, Issue 17, 2014, Pages 1885-1899

  Sexton, Alec N ^a   Regalado, Samuel G ^a   Lai, Christine S ^b   Cost, Gregory J ^c   O'Neil, Colleen M ^c   Urnov, Fyodor D ^c   Gregory, Philip D ^c   Jaenisch, Rudolf ^b   Collins, Kathleen ^a   Hockemeyer, Dirk ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c SANGAMO BIOSCIENCES INC   (United States)

Author keywords

Embryonic stem cells; Human genome engineering; Shelterin; Telomerase; Telomere maintenance

Indexed keywords

EMBRYONIC STEM CELLS; HUMAN GENOME ENGINEERING; SHELTERIN; TELOMERASE; TELOMERE MAINTENANCE;

AMINOPEPTIDASES; DIPEPTIDYL-PEPTIDASES AND TRIPEPTIDYL-PEPTIDASES; EMBRYONIC STEM CELLS; ENZYME ACTIVATION; GENE KNOCKOUT TECHNIQUES; GENETIC COMPLEMENTATION TEST; HUMANS; PROTO-ONCOGENE PROTEINS C-ETS; REPRESSOR PROTEINS; SERINE PROTEASES; TELOMERASE; TELOMERE; TELOMERE HOMEOSTASIS; TELOMERE-BINDING PROTEINS;

EID: 84906886498     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.246819.114     Document Type: Article

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