Individual and combined effects of genistein and hesperidin on immunity and intestinal morphometry in lipopolysacharide-challenged broiler chickens

Poultry Science

Volumn 93, Issue 9, 2014, Pages 2175-2183

  Kamboh, A A ^a,b   Zhu, W Y ^a  

^a NANJING AGRICULTURAL UNIVERSITY   (China)

^b SINDH AGRICULTURE UNIVERSITY   (Pakistan)

Author keywords

Genistein; Hesperidin; Immunity; Lipopolysaccharide; Morphometry

Indexed keywords

GENISTEIN; HESPERIDIN; LIPOPOLYSACCHARIDE; PROTEIN KINASE INHIBITOR;

ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; CHICKEN; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET; DIET SUPPLEMENTATION; DRUG EFFECT; ESCHERICHIA COLI; FEMALE; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; IMMUNITY; IMMUNOLOGY; IMMUNOMODULATION; INTESTINE; MALE; MORPHOMETRICS; RANDOMIZED CONTROLLED TRIAL;

GENISTEIN; HESPERIDIN; IMMUNITY; LIPOPOLYSACCHARIDE; MORPHOMETRY;

ANIMAL FEED; ANIMALS; CHICKENS; DIET; DIETARY SUPPLEMENTS; ESCHERICHIA COLI; FEMALE; GENISTEIN; HESPERIDIN; IMMUNOMODULATION; INTESTINES; LIPOPOLYSACCHARIDES; MALE; PROTEIN KINASE INHIBITORS;

GALLUS GALLUS;

EID: 84906875712     PISSN: 00325791     EISSN: 15253171     Source Type: Journal    
DOI: 10.3382/ps.2014-03971     Document Type: Article

References (38)

1. Alvarez, M. A., N. B. Debattista, and N. B. Pappano. 2008. Antimicrobial activity and synergism of some substituted flavonoids. Folia Microbiol. (Praha) 53: 23-28.
2. Awad, W. A., K. Ghareeb, and J. Bohm. 2011. Evaluation of the chicory inulin efficacy on ameliorating the intestinal morphology and modulating the intestinal electrophysiological properties in broiler chickens. J. Anim. Physiol. Anim. Nutr. (Berl.) 95: 65-72.
3. Bowen, O. T., R. L. Dienglewicz, R. F. Wideman, and G. F. Erf. 2009. Altered monocyte and macrophage numbers in blood and organs of chickens injected i.v. with lipopolysaccharide. Vet. Immunol. Immunopathol. 131: 200-210.
4. Calixto, J. B., M. M. Campos, M. F. Otuki, and A. R. Santos. 2004. Anti-inflammatory compounds of plant origin. Part II. Modulation of pro-inflammatory cytokines, chemokines and adhesion molecules. Planta Med. 70: 93-103.
5. Cheng, H. W., R. Freire, and E. A. Pajor. 2004. Endotoxin stress responses in chickens from different genetic lines. 1. Sickness, behavioral, and physical responses. Poult. Sci. 83: 707-715.
6. Damre, A. S., A. B. Gokhale, A. S. Phadke, K. R. Kulkarni, and M. N. Saraf. 2003. Studies on the immunomodulatory activity of flavonoidal fraction of tephrosia purpurea. Fitoterapia 74: 257-261.
7. Dong, X. F., W. W. Gao, J. M. Tong, H. Q. Jia, R. N. Sa, and Q. Zhang. 2007. Effect of polysavone (alfalfa extract) on abdominal fat deposition and immunity in broiler chickens. Poult. Sci. 86: 1955-1959.
8. Frolich, S., J. Farhat, and M. Wallach. 2013. Designing strategies for the control of coccidiosis in chickens on poultry farms using modern diagnostic tools. Reports in Parasitol. 3: 1-10.
9. Giannenas, I., D. Tontis, E. Tsalie, E. F. Chronis, D. Doukas, and I. Kyriazakis. 2010. Influence of dietary mushroom agaricus bisporus on intestinal morphology and microflora composition in broiler chickens. Res. Vet. Sci. 89: 78-84.
10. Gu, B., J. You, Y. Li, C. Duan, and M. Fang. 2010. Enteric-coated garlic supplement markedly enhanced normal mice immunocompetence. Eur. Food Res. Technol. 230: 627-634.
11. Hanieh, H., C. Gerile, K. Narabara, Z. Gu, A. Abe, and Y. Kondo. 2010. In vivo immunomodulatory effects of dietary purple sweet potato after immunization in chicken. Anim. Sci. J. 81: 116-121.
12. Hassanpour, H., M. A. K. Zamani, A. Yazdani, and B. M. Cheraghchi. 2010. Evaluation of intestinal morphology and nitric oxide metabolites in broiler chickens supplemented by green tea. Comp. Clin. Pathol. 19: 43-47.
13. Hooper, L. V., M. H. Wong, A. Thelin, L. Hansson, P. G. Falk, and J. I. Gordon. 2001. Molecular analysis of commensal hostmicrobial relationships in the intestine. Science 291: 881-884.
14. Hu, X., Y. Guo, J. Li, G. Yan, S. Bun, and B. Huang. 2011. Effects of an early lipopolysaccharide challenge on growth and small intestinal structure and function of broiler chickens. Can. J. Anim. Sci. 91: 379-384.
15. Hu, Z., and Y. Guo. 2007. Effects of dietary sodium butyrate supplementation on the intestinal morphological structure, absorptive function and gut flora in chickens. Anim. Feed Sci. Technol. 132: 240-249.
16. Jiang, Z. Y., S. Q. Jiang, Y. C. Lin, P. B. Xi, D. Q. Yu, and T. X. Wu. 2007. Effects of soybean isoflavone on growth performance, meat quality, and antioxidation in male broilers. Poult. Sci. 86: 1356-1362.
17. Kamboh, A. A., and W. Y. Zhu. 2013a. Individual and combined effects of genistein and hesperidin supplementation on meat quality in meat-type broiler chickens. J. Sci. Food Agric. 93: 3362-3367. http://dx.doi.org/10.1002/jsfa. 6185.
18. Kamboh, A. A., and W. Y. Zhu. 2013b. Effects of genistein and hesperidin on biomarkers of heat stress in broilers under persistent summer stress. Poult. Sci. 92: 2411-2418.
19. Kamboh, A. A., and W. Y. Zhu. 2013c. Effect of increasing levels of bioflavonoids in broiler feed on plasma anti-oxidative potential, lipid metabolites, and fatty acid composition of meat. Poult. Sci. 92: 454-461.
20. Kawaguchi, K., S. Kikuchi, R. Hasunuma, H. Maruyama, T. Yoshikawa, and Y. Kumazawa. 2004. A citrus flavonoid hesperidin suppresses infection-induced endotoxin shock in mice. Biol. Pharm. Bull. 27: 679-683.
21. Laparra, J. M., and Y. Sanz. 2010. Interactions of gut microbiota with functional food components and nutraceuticals. Pharmacol. Res. 61: 219-225.
22. Lew, W. Y. W., E. Bayna, E. D. Molle, N. D. Dalton, N. C. Lai, V. Bhargava, V. Mendiola, P. Clopton, and T. Tang. 2013. Recurrent exposure to subclinical lipopolysaccharide increases mortality and induces cardiac fibrosis in mice. PLoS ONE 8: e61057 http://dx.doi.org/10.1371/journal.pone.0061057.
23. Mahmoud, M., D. Hamdan, M. Wink, and A. El-Shazly. 2013. Naringin and rutin prevent D-Galactosamine-induced hepatic injury in rats via attenuation of the inflammatory cascade and oxidative stress. Eur. Sci. J. 9: 141-155.
24. Maitra, U., H. Deng, T. Glaros, B. Baker, D. G. Capelluto, Z. Li, and L. Li. 2012. Molecular mechanisms responsible for the selective and low-grade induction of proinflammatory mediators in murine macrophages by lipopolysaccharide. J. Immunol. 189: 1014-1023.
25. Miller, M., F. Angeles, B. Reuter, P. Bobrowski, and M. Sandoval. 2001. Dietary antioxidants protect gut epithelial cells from oxidant-induced apoptosis. BMC Complement. Altern. Med. 1: 11.
26. Muller, S., P. Hoffmann, U. V. Esche, J. P. Mach, R. M. Gorczynski, T. Waelli, C. Alexander, U. Zahringer, E. T. Rietschel, W. G. Bessler, and O. Westphal. 2005. A fetal sheep liver extract containing immunostimulatory substances including LPS acts as leukocyte activator in cells of LPS responder and non responder mice. Int. Immunopharmacol. 5: 1809-1819.
27. Ogikubo, Y., M. Orimatsu, Y. Sasaki, A. Yasuda, J. Saegusa, and Y. Tamura. 2004. Effect of lipopolysaccharide (LPS) injection on the immune responses of LPS-sensitive mice. J. Vet. Med. Sci. 66: 1189-1193.
28. Pena, J. E. M., S. L. Vieira, J. López, R. N. Reis, R. Barros, F. V. F. Furtado, and P. X. Silva. 2008. Ascorbic acid and citric flavonoids for broilers under heat stress: Effects on performance and meat quality. Braz. J. Poult. Sci. 10: 125-130.
29. Pignatelli, P., F. M. Pulcinelli, A. Celestini, L. Lenti, A. Ghiselli, P. P. Gazzaniga, and F. Violi. 2000. The flavonoids quercetin and catechin synergistically inhibit platelet function by antagonizing the intracellular production of hydrogen peroxide. Am. J. Clin. Nutr. 72: 1150-1155.
30. Pilkhwal, S., N. Tirkey, A. Kuhad, and K. Chopra. 2010. Effect of bioflavonoid quercetin on endotoxin-induced hepatotoxicity and oxidative stress in rat liver. Iranian J. Pharmacol. Ther. 9: 47-53.
31. Shukla, S., A. Mehta, J. John, P. Mehta, S. P. Vyas, and S. Shukla. 2009. Immunomodulatory activities of the ethanolic extract of caesalpinia bonducella seeds. J. Ethnopharmacol. 125: 252-256.
32. SPSS. 1999. Spss Version 10. 0 for Windows. SPSS Inc., Chicago, IL.
33. Ting, S., H. S. Yeh, and T. F. Lien. 2011. Effects of supplemental levels of hesperetin and naringenin on egg quality, serum traits and antioxidant activity of laying hens. Anim. Feed Sci. Technol. 163: 59-66.
34. Wallace, R. J., W. Oleszek, C. Franz, I. Hahn, K. H. Baser, A. Mathe, and K. Teichmann. 2010. Dietary plant bioactives for poultry health and productivity. Br. Poult. Sci. 51: 461-487.
35. Wang, Y., Z. Jiang, Z. Jin, H. Tan, and B. Xu. 2013. Risk factors for infectious diseases in backyard poultry farms in the poyang lake area, china. PLoS ONE 8: e67366 http://dx.doi.org/10.1371/journal.pone.0067366.
36. Xie, H., N. C. Rath, G. R. Huff, W. E. Huff, and J. M. Balog. 2000. Effects of Salmonella typhimurium lipopolysaccharide on broiler chickens. Poult. Sci. 79: 33-40.
37. Young, J. F., J. Stagsted, S. K. Jensen, A. H. Karlsson, and P. Henckel. 2003. Ascorbic acid, alpha-tocopherol, and oregano supplements reduce stress-induced deterioration of chicken meat quality. Poult. Sci. 82: 1343-1351.
38. Zhang, X., X. Zhong, Y. Zhou, G. Wang, H. Du, and T. Wang. 2010. Dietary RRR-a-tocopherol succinate attenuates lipopolysaccharide-induced inflammatory cytokines secretion in broiler chicks. Br. J. Nutr. 104: 1796-1805.