Enteric-coated garlic supplement markedly enhanced normal mice immunocompetence

European Food Research and Technology

Volumn 230, Issue 4, 2010, Pages 627-634

  Gu, Bing ^a   You, Jian ^b   Li, Yuping ^a   Duan, Chunlin ^c   Fang, Meimei ^b  

^a JIANGXI SCIENCE AND TECHNOLOGY NORMAL UNIVERSITY   (China)

^b National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine   (China)

^c Jiangxi Institute of Materia Medica   (China)

Author keywords

Cell mediated immunity; Cytokines; Enteric coated tablets; Garlic (Allium sativum L.); Humoral immunity; Mononuclear phagocytic system; Natural killer cells

Indexed keywords

ALLIUM SATIVUM; COATED TABLETS; CYTOKINES; HUMORAL IMMUNITY; MONONUCLEAR PHAGOCYTIC SYSTEM; NATURAL KILLER CELLS;

ANIMALS; BODY FLUIDS; DISTILLATION; HIP PROSTHESES; TOXICITY;

BALL MILLING;

ALLIUM SATIVUM; ANIMALIA; BACTERIA (MICROORGANISMS); MUS;

EID: 76149112550     PISSN: 14382377     EISSN: 14382385     Source Type: Journal    
DOI: 10.1007/s00217-009-1202-1     Document Type: Article

References (28)

1. Stengler M, Balch JF (2002) The natural physician's healing therapies: proven remedies that medical doctors don't know. Penguin Group, USA, pp 196-199.
2. Ackermann RT, Mulrow CD, Ramirez G et al (2001) Garlic shows promise for improving some cardiovascular risk factors. Arch Intern Med 161(6): 813-824.
3. Amagase H, Petesch BL, Matsuura H et al (2001) Intake of garlic and its bioactive components. J Nutr 131(3s): 955S-962S.
4. Bruck R, Aeed H, Brazovsky E et al (2005) Allicin, the active component of garlic, prevents immune-mediated, concanavalin A-induced hepatic injury in mice. Liver Int 25(3): 613-621.
5. Davis ME, Brewster ME (2004) Cyclodextrin-based pharmaceutics: past, present and future. Nat Rev Drug Discov 3(12): 1023-1035.
6. Loftsson T, Vogensen SB, Brewster ME, Konrádsdóttir F (2007) Effects of cyclodextrins on drug delivery through biological membranes. J Pharm Sci 96(10): 2532-2546.
7. Butt MS, Sultan MT, Butt MS, Iqabl J (2009) Garlic: nature's protection against physiological threats. Crit Rev Food Sci Nutr 49(6): 538-551.
8. Gu B, Li HN, Li YP, Luo GM (2009) Studies on enhanced immunocompentence by garlic (Allium sativum L.): a review. Zhong Yao Cai 32(7): 1164-1168.
9. Xu HX, Liu XP, Liu Y et al (2005) Study on inclusion technology of garlic essential oil and beta -cyclodextrin. Zhong Yao Cai 28(4): 341-342.
10. Desai HG, Kalro RH, Choksi AP (1990) Effect of ginger and garlic on DNA content of gastric aspirate. Indian J Med Res 92(1): 139-141.
11. de Diego M, Avello M, Mennickent S et al (2007) Validated liquid chromatographic method for quantitative determination of allicin in garlic powder and tablets. J Sep Sci 30(16): 2703-2707.
12. Feng YH, Zhu YN, Liu J et al (2004) Differential regulation of resveratrol on lipopolysacchride stimulated human macrophages with or without IFN-gamma pre-priming. Int Immunopharmacol 4(6): 713-720.
13. Feng YH, Zhou WL, Wu QL et al (2002) Low dose of resveratrol enhanced immune response of mice. Acta Pharmacol Sin 23(10): 893-897.
14. Wu QL, Fu YF, Zhou WL et al (2005) Inhibition of S-adenosyl-l-homocysteine hydrolase induces immunosuppression. J Pharmacol Exp Ther 313(2): 705-711.
15. Kaliss N (1971) Jerne plaque assay for antibody-forming spleen cells: some technical modifications. Transplantation 12(2): 146-147.
16. Yang FM, Shi Y, Sheng JC, Hu QH (2006) In vivo immunomodulatory activity of polysaccharides derived from Chlorella pyrenoidosa. Eur Food Res Technol 224(2): 225-228.
17. Yuan H, Song J, Li X et al (2006) Immunomodulation and antitumor activity of kappa-carrageenan oligosaccharides. Cancer Lett 243(2): 228-234.
18. Okimura T, Ogawa M, Yamauchi T (1986) Stress immune responses III. Effect of restraint stress on delayed type hypersensitivity (DTH) response, natural killer (NK) activity and phagocytosis in mice. Jpn J Pharmacol 41(2): 229-235.
19. Yang HY, Liu SL, Ibrahim SA et al (2009) Oral administration of live Bifidobacterium substrains isolated from healthy centenarians enhanced immune function in BALB/c mice. Nutr Res 29(4): 281-289.
20. Kim KD, Choi SC, Kim A et al (2001) Dendritic cell-tumor coculturing vaccine can induce antitumor immunity through both NK and CTL interaction. Int Immunopharmacol 1(12): 2117-2129.
21. Perkins DL (1998) T cell activation in autoimmune and inflammatory diseases. Curr Opin Nephrol Hypertens 7(3): 297-303.
22. Kobayashi K, Kaneda K, Kasama T (2001) Immunopathogenesis of delayed-type hypersensitivity. Microsc Res Tech 53(4): 241-245.
23. Simpson MA, Gozzo JJ (1978) Spectrophotometric determination of lymphocyte mediated sheep red blood cell hemolysis in vitro. J Immunol Methods 21(1-2): 159-165.
24. Ishimoto H, Yanagihara K, Araki N et al (2008) Single-cell observation of phagocytosis by human blood dendritic cells. Jpn J Infect Dis 61(4): 294-297.
25. Roitt IM, Brostoff J, Male DK (2001) Immunology, 6th edn. Mosby, St. Louis. ISBN 0723431892. 2001: 480.
26. Old LJ (1985) Tumor necrosis factor (TNF). Science 230(4726): 630-632.
27. Asano Y, Kaneda K, Hiragushi J et al (1997) The tumor-bearing state induces augmented responses of organ-associated lymphocytes to high-dose interleukin-2 therapy in mice. Cancer Immunol Immunother 45(2): 63-70.
28. Amagase H (2006) Clarifying the real bioactive constituents of garlic. J Nutr 136(3 Suppl): 716S-725S.