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Volumn 35, Issue 9, 2014, Pages 1983-1992

Posttranscriptional control of the chemokine receptor CXCR4 expression in cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

3' UNTRANSLATED REGIONS; AU RICH ELEMENTS; CHEMOKINE CXCL12; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HALF-LIFE; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; HUMANS; MCF-7 CELLS; MICRORNAS; RECEPTORS, CXCR4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA STABILITY; RNA, MESSENGER; TRISTETRAPROLIN;

EID: 84906837700     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgu080     Document Type: Article
Times cited : (33)

References (51)
  • 1
    • 84877112601 scopus 로고    scopus 로고
    • The role of CXC chemokines and their receptors in the progression and treatment of tumors
    • Zhu, Q. et al. (2012) The role of CXC chemokines and their receptors in the progression and treatment of tumors. J. Mol. Histol., 43, 699-713.
    • (2012) J. Mol. Histol. , vol.43 , pp. 699-713
    • Zhu, Q.1
  • 2
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • Müller, A. et al. (2001) Involvement of chemokine receptors in breast cancer metastasis. Nature, 410, 50-56.
    • (2001) Nature , vol.410 , pp. 50-56
    • Müller, A.1
  • 3
    • 84871412842 scopus 로고    scopus 로고
    • A review on CXCR4/CXCL12 axis in oncology: no place to hide
    • Domanska, U.M. et al. (2013) A review on CXCR4/CXCL12 axis in oncology: no place to hide. Eur. J. Cancer, 49, 219-230.
    • (2013) Eur. J. Cancer , vol.49 , pp. 219-230
    • Domanska, U.M.1
  • 4
    • 0034144269 scopus 로고    scopus 로고
    • Chemokines: a new classification system and their role in immunity
    • Zlotnik, A. et al. (2000) Chemokines: a new classification system and their role in immunity. Immunity, 12, 121-127.
    • (2000) Immunity , vol.12 , pp. 121-127
    • Zlotnik, A.1
  • 5
    • 0037085938 scopus 로고    scopus 로고
    • Use of the stromal cell-derived factor-1/ CXCR4 pathway in prostate cancer metastasis to bone
    • Taichman, R.S. et al. (2002) Use of the stromal cell-derived factor-1/ CXCR4 pathway in prostate cancer metastasis to bone. Cancer Res., 62, 1832-1837.
    • (2002) Cancer Res. , vol.62 , pp. 1832-1837
    • Taichman, R.S.1
  • 6
    • 0038079014 scopus 로고    scopus 로고
    • The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases
    • Zeelenberg, I.S. et al. (2003) The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases. Cancer Res., 63, 3833-3839.
    • (2003) Cancer Res. , vol.63 , pp. 3833-3839
    • Zeelenberg, I.S.1
  • 7
    • 0345687920 scopus 로고    scopus 로고
    • Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells
    • Burger, M. et al. (2003) Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells. Oncogene, 22, 8093-8101.
    • (2003) Oncogene , vol.22 , pp. 8093-8101
    • Burger, M.1
  • 8
    • 3142512612 scopus 로고    scopus 로고
    • Molecular characterization of the tumor microenvironment in breast cancer
    • Allinen, M. et al. (2004) Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell, 6, 17-32.
    • (2004) Cancer Cell , vol.6 , pp. 17-32
    • Allinen, M.1
  • 9
    • 0141685979 scopus 로고    scopus 로고
    • Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma
    • Kato, M. et al. (2003) Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma. Breast Cancer Res., 5, R144-R150.
    • (2003) Breast Cancer Res. , vol.5
    • Kato, M.1
  • 10
    • 20144389833 scopus 로고    scopus 로고
    • Expression of CXCR4 predicts poor prognosis in patients with malignant melanoma
    • Scala, S. et al. (2005) Expression of CXCR4 predicts poor prognosis in patients with malignant melanoma. Clin. Cancer Res., 11, 1835-1841.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 1835-1841
    • Scala, S.1
  • 11
    • 84884125127 scopus 로고    scopus 로고
    • The impact of chemokine receptor CXCR4 on breast cancer prognosis: a meta-analysis
    • Xu, T.P. et al. (2013) The impact of chemokine receptor CXCR4 on breast cancer prognosis: a meta-analysis. Cancer Epidemiol., 37, 725-731.
    • (2013) Cancer Epidemiol. , vol.37 , pp. 725-731
    • Xu, T.P.1
  • 12
    • 84859254923 scopus 로고    scopus 로고
    • Sequence variations affecting AU-rich element function and disease
    • Hitti, E. et al. (2012) Sequence variations affecting AU-rich element function and disease. Front. Biosci. (Landmark Ed)., 17, 1846-1860.
    • (2012) Front. Biosci. (Landmark Ed). , vol.17 , pp. 1846-1860
    • Hitti, E.1
  • 13
    • 33644876034 scopus 로고    scopus 로고
    • ARED 3.0: the large and diverse AU-rich transcriptome
    • Database issue
    • Bakheet, T. et al. (2006) ARED 3.0: the large and diverse AU-rich transcriptome. Nucleic Acids Res., 34(Database issue), D111-D114.
    • (2006) Nucleic Acids Res. , vol.34
    • Bakheet, T.1
  • 14
    • 77956727472 scopus 로고    scopus 로고
    • Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements
    • Khabar, K.S. (2010) Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements. Cell. Mol. Life Sci., 67, 2937-2955.
    • (2010) Cell. Mol. Life Sci. , vol.67 , pp. 2937-2955
    • Khabar, K.S.1
  • 15
    • 4143134276 scopus 로고    scopus 로고
    • Expression of the ELAV-like protein HuR is associated with higher tumor grade and increased cyclooxygenase-2 expression in human breast carcinoma
    • Denkert, C. et al. (2004) Expression of the ELAV-like protein HuR is associated with higher tumor grade and increased cyclooxygenase-2 expression in human breast carcinoma. Clin. Cancer Res., 10, 5580-5586.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 5580-5586
    • Denkert, C.1
  • 16
    • 0035213198 scopus 로고    scopus 로고
    • Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells
    • Dixon, D.A. et al. (2001) Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells. J. Clin. Invest., 108, 1657-1665.
    • (2001) J. Clin. Invest. , vol.108 , pp. 1657-1665
    • Dixon, D.A.1
  • 17
    • 38849112559 scopus 로고    scopus 로고
    • Expression of the ELAV-like protein HuR in human prostate carcinoma is an indicator of disease relapse and linked to COX-2 expression
    • Niesporek, S. et al. (2008) Expression of the ELAV-like protein HuR in human prostate carcinoma is an indicator of disease relapse and linked to COX-2 expression. Int. J. Oncol., 32, 341-347.
    • (2008) Int. J. Oncol. , vol.32 , pp. 341-347
    • Niesporek, S.1
  • 18
    • 77954952745 scopus 로고    scopus 로고
    • The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes
    • Al-Souhibani, N. et al. (2010) The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes. Oncogene, 29, 4205-4215.
    • (2010) Oncogene , vol.29 , pp. 4205-4215
    • Al-Souhibani, N.1
  • 19
    • 65349120262 scopus 로고    scopus 로고
    • The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis
    • Young, L.E. et al. (2009) The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis. Gastroenterology, 136, 1669-1679.
    • (2009) Gastroenterology , vol.136 , pp. 1669-1679
    • Young, L.E.1
  • 20
    • 67449132368 scopus 로고    scopus 로고
    • The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis
    • Brennan, C.M., et al. (2009) The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis. Cancer Res, 69, 5168-5176.
    • (2009) Cancer Res , vol.69 , pp. 5168-5176
    • Brennan, C.M.1
  • 21
    • 33845431240 scopus 로고    scopus 로고
    • Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts
    • Lai, W.S. et al. (2006) Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts. Mol. Cell. Biol., 26, 9196-9208.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 9196-9208
    • Lai, W.S.1
  • 22
    • 84876154977 scopus 로고    scopus 로고
    • miR-29a inhibition normalizes HuR overexpression and aberrant AU-rich mRNA stability in invasive cancer
    • Al-Ahmadi, W. et al. (2013) miR-29a inhibition normalizes HuR overexpression and aberrant AU-rich mRNA stability in invasive cancer. J. Pathol., 230, 28-38.
    • (2013) J. Pathol. , vol.230 , pp. 28-38
    • Al-Ahmadi, W.1
  • 23
    • 67649842761 scopus 로고    scopus 로고
    • Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto- Regulation
    • Al-Ahmadi, W. et al. (2009) Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto- Regulation. Nucleic Acids Res., 37, 3612-3624.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 3612-3624
    • Al-Ahmadi, W.1
  • 24
    • 13444265875 scopus 로고    scopus 로고
    • Silencing of CXCR4 blocks breast cancer metastasis
    • Liang, Z. et al. (2005) Silencing of CXCR4 blocks breast cancer metastasis. Cancer Res., 65, 967-971.
    • (2005) Cancer Res. , vol.65 , pp. 967-971
    • Liang, Z.1
  • 25
    • 77952691844 scopus 로고    scopus 로고
    • A versatile ribosomal protein promoter-based reporter system for selective assessment of RNA stability and post-transcriptional control
    • Hitti, E. et al. (2010) A versatile ribosomal protein promoter-based reporter system for selective assessment of RNA stability and post-transcriptional control. RNA, 16, 1245-1255.
    • (2010) RNA , vol.16 , pp. 1245-1255
    • Hitti, E.1
  • 26
    • 0037088665 scopus 로고    scopus 로고
    • Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs
    • Lai, W.S. et al. (2002) Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs. J. Biol. Chem., 277, 9606-9613.
    • (2002) J. Biol. Chem. , vol.277 , pp. 9606-9613
    • Lai, W.S.1
  • 27
    • 0034080318 scopus 로고    scopus 로고
    • The biology of chemokines and their receptors
    • Rossi, D. et al. (2000) The biology of chemokines and their receptors. Annu. Rev. Immunol., 18, 217-242.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 217-242
    • Rossi, D.1
  • 28
    • 0032508033 scopus 로고    scopus 로고
    • The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract
    • Tachibana, K. et al. (1998) The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature, 393, 591-594.
    • (1998) Nature , vol.393 , pp. 591-594
    • Tachibana, K.1
  • 29
    • 0032507962 scopus 로고    scopus 로고
    • Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
    • Zou, Y.R. et al. (1998) Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature, 393, 595-599.
    • (1998) Nature , vol.393 , pp. 595-599
    • Zou, Y.R.1
  • 30
    • 23844513413 scopus 로고    scopus 로고
    • Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1- CXCR4 axis
    • Kucia, M. et al. (2005) Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1- CXCR4 axis. Stem Cells, 23, 879-894.
    • (2005) Stem Cells , vol.23 , pp. 879-894
    • Kucia, M.1
  • 31
    • 80053124540 scopus 로고    scopus 로고
    • A synthetic biology approach reveals a CXCR4-G13- Rho signaling axis driving transendothelial migration of metastatic breast cancer cells
    • Yagi, H. et al. (2011) A synthetic biology approach reveals a CXCR4-G13- Rho signaling axis driving transendothelial migration of metastatic breast cancer cells. Sci. Signal., 4, ra60.
    • (2011) Sci. Signal. , vol.4
    • Yagi, H.1
  • 32
    • 33344464945 scopus 로고    scopus 로고
    • CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment
    • Burger, J.A. et al. (2006) CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood, 107, 1761-1767.
    • (2006) Blood , vol.107 , pp. 1761-1767
    • Burger, J.A.1
  • 33
    • 33645668431 scopus 로고    scopus 로고
    • Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy
    • Muller, A. et al. (2006) Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. Int. J. Cancer, 118, 2147-2157.
    • (2006) Int. J. Cancer , vol.118 , pp. 2147-2157
    • Muller, A.1
  • 34
    • 23944464166 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4 expression in breast cancer as a potential predictive marker of isolated tumor cells in bone marrow
    • Cabioglu, N. et al. (2005) Chemokine receptor CXCR4 expression in breast cancer as a potential predictive marker of isolated tumor cells in bone marrow. Clin. Exp. Metastasis, 22, 39-46.
    • (2005) Clin. Exp. Metastasis , vol.22 , pp. 39-46
    • Cabioglu, N.1
  • 35
    • 33745334601 scopus 로고    scopus 로고
    • The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study
    • Salvucci, O. et al. (2006) The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study. Breast Cancer Res. Treat., 97, 275-283.
    • (2006) Breast Cancer Res. Treat. , vol.97 , pp. 275-283
    • Salvucci, O.1
  • 36
    • 0033818476 scopus 로고    scopus 로고
    • Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression
    • Koshiba, T. et al. (2000) Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression. Clin. Cancer Res., 6, 3530-3535.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3530-3535
    • Koshiba, T.1
  • 37
    • 38549113982 scopus 로고    scopus 로고
    • ARED Organism: expansion of ARED reveals AU-rich element cluster variations between human and mouse
    • Database issue
    • Halees, A.S. et al. (2008) ARED Organism: expansion of ARED reveals AU-rich element cluster variations between human and mouse. Nucleic Acids Res., 36(Database issue), D137-D140.
    • (2008) Nucleic Acids Res. , vol.36
    • Halees, A.S.1
  • 38
    • 0029918710 scopus 로고    scopus 로고
    • Functional characterization of a non-AUUUA AU-rich element from the c-jun proto-oncogene mRNA: evidence for a novel class of AU-rich elements
    • Peng, S.S. et al. (1996) Functional characterization of a non-AUUUA AU-rich element from the c-jun proto-oncogene mRNA: evidence for a novel class of AU-rich elements. Mol. Cell. Biol., 16, 1490-1499.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1490-1499
    • Peng, S.S.1
  • 39
    • 0035162672 scopus 로고    scopus 로고
    • ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins
    • Bakheet, T. et al. (2001) ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins. Nucleic Acids Res., 29, 246-254.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 246-254
    • Bakheet, T.1
  • 40
    • 0030872398 scopus 로고    scopus 로고
    • Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay
    • Xu, N. et al. (1997) Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay. Mol. Cell. Biol., 17, 4611-4621.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4611-4621
    • Xu, N.1
  • 41
    • 84866951611 scopus 로고    scopus 로고
    • The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation
    • Tiedje, C. et al. (2012) The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation. PLoS Genet., 8, e1002977.
    • (2012) PLoS Genet. , vol.8
    • Tiedje, C.1
  • 42
    • 84863116439 scopus 로고    scopus 로고
    • AU-rich-element-dependent translation repression requires the cooperation of tristetraprolin and RCK/P54
    • Qi, M.Y. et al. (2012) AU-rich-element-dependent translation repression requires the cooperation of tristetraprolin and RCK/P54. Mol. Cell. Biol., 32, 913-928.
    • (2012) Mol. Cell. Biol. , vol.32 , pp. 913-928
    • Qi, M.Y.1
  • 43
    • 77951667118 scopus 로고    scopus 로고
    • Functional switching of TGF-beta1 signaling in liver cancer via epigenetic modulation of a single CpG site in TTP promoter
    • Sohn, B.H. et al. (2010) Functional switching of TGF-beta1 signaling in liver cancer via epigenetic modulation of a single CpG site in TTP promoter. Gastroenterology, 138, 1898-1908.
    • (2010) Gastroenterology , vol.138 , pp. 1898-1908
    • Sohn, B.H.1
  • 44
    • 81255147990 scopus 로고    scopus 로고
    • A synonymous polymorphism of the Tristetraprolin (TTP) gene, an AU-rich mRNA-binding protein, affects translation efficiency and response to Herceptin treatment in breast cancer patients
    • Griseri, P. et al. (2011) A synonymous polymorphism of the Tristetraprolin (TTP) gene, an AU-rich mRNA-binding protein, affects translation efficiency and response to Herceptin treatment in breast cancer patients. Hum. Mol. Genet., 20, 4556-4568.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 4556-4568
    • Griseri, P.1
  • 45
    • 84864634079 scopus 로고    scopus 로고
    • Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state
    • Rounbehler, R.J. et al. (2012) Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state. Cell, 150, 563-574.
    • (2012) Cell , vol.150 , pp. 563-574
    • Rounbehler, R.J.1
  • 46
    • 84870190401 scopus 로고    scopus 로고
    • Genetic polymorphisms in RNA binding proteins contribute to breast cancer survival
    • Upadhyay, R. et al. (2013) Genetic polymorphisms in RNA binding proteins contribute to breast cancer survival. Int. J. Cancer, 132, E128-E138.
    • (2013) Int. J. Cancer , vol.132
    • Upadhyay, R.1
  • 47
    • 33747601610 scopus 로고    scopus 로고
    • Expression of the ELAV-like protein HuR in human colon cancer: association with tumor stage and cyclooxygenase-2
    • Denkert, C. et al. (2006) Expression of the ELAV-like protein HuR in human colon cancer: association with tumor stage and cyclooxygenase-2. Mod. Pathol., 19, 1261-1269.
    • (2006) Mod. Pathol. , vol.19 , pp. 1261-1269
    • Denkert, C.1
  • 48
    • 0141640857 scopus 로고    scopus 로고
    • Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2
    • Tran, H. et al. (2003) Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2. Mol. Cell. Biol., 23, 7177-7188.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 7177-7188
    • Tran, H.1
  • 49
    • 79955854286 scopus 로고    scopus 로고
    • Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP-9
    • Yuan, Z. et al. (2011) Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP-9. Oncol. Rep., 26, 237-245.
    • (2011) Oncol. Rep. , vol.26 , pp. 237-245
    • Yuan, Z.1
  • 50
    • 79955445350 scopus 로고    scopus 로고
    • CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti-VEGF treatment or docetaxel in a transgenic mouse model
    • Hassan, S. et al. (2011) CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti-VEGF treatment or docetaxel in a transgenic mouse model. Int. J. Cancer, 129, 225-232.
    • (2011) Int. J. Cancer , vol.129 , pp. 225-232
    • Hassan, S.1
  • 51
    • 84871015161 scopus 로고    scopus 로고
    • Halting metastasis through CXCR4 inhibition
    • Ramsey, D.M. et al. (2013) Halting metastasis through CXCR4 inhibition. Bioorg. Med. Chem. Lett., 23, 20-25.
    • (2013) Bioorg. Med. Chem. Lett. , vol.23 , pp. 20-25
    • Ramsey, D.M.1


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