Metabolism of 1α-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1α,20-dihydroxyvitamin D3

Journal of Steroid Biochemistry and Molecular Biology

Volumn 112, Issue 4-5, 2008, Pages 213-219

  Tuckey, Robert C ^a   Janjetovic, Zorica ^b   Li, Wei ^c   Nguyen, Minh N ^a   Zmijewski, Michal A ^b   Zjawiony, Jordan ^d   Slominski, Andrzej ^b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b Center for Cancer Research   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^d UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

CYP11A1; Keratinocytes; NMR; Vitamin D

Indexed keywords

1ALPHA,20 DIHYDROXYVITAMIN D3; ALFACALCIDOL; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); UNCLASSIFIED DRUG; 1-HYDROXYCHOLECALCIFEROL; 1ALPHA,20-DIHYDROXYVITAMIN D3; HYDROXYCOLECALCIFEROL; STEROID MONOOXYGENASE; VITAMIN D 24 HYDROXYLASE; VITAMIN D 24-HYDROXYLASE;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA SYNTHESIS; HUMAN; HUMAN CELL; HYDROXYLATION; KERATINOCYTE; NUCLEAR MAGNETIC RESONANCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; BIOSYNTHESIS; CATTLE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION; KINETICS; METABOLISM;

ANIMALS; CATTLE; CELL PROLIFERATION; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; GENE EXPRESSION; HUMANS; HYDROXYCHOLECALCIFEROLS; KERATINOCYTES; KINETICS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; STEROID HYDROXYLASES;

EID: 57649103616     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2008.10.005     Document Type: Article

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