Cell sheet approach for tissue engineering and regenerative medicine

Journal of Controlled Release

Volumn 190, Issue , 2014, Pages 228-239

  Matsuura, Katsuhisa ^a   Utoh, Rie ^a   Nagase, Kenichi ^a   Okano, Teruo ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Cell sheet; Regenerative medicine

Indexed keywords

CYTOLOGY; REGENERATIVE MEDICINE; SCAFFOLDS (BIOLOGY); STEM CELLS; TISSUE; TISSUE REGENERATION; REPAIR; TRANSPLANTATION (SURGICAL);

AUTOLOGOUS CELL; CELL SHEET; CELL SHEET TECHNOLOGIES; CLINICAL SETTINGS; PERIODONTAL LIGAMENT; STEM CELL BIOLOGY; TRANSPLANTED CELLS; VASCULARIZATION; REGENERATIVE MEDICINE;

CELL ENGINEERING;

CYTOKINE; GROWTH FACTOR;

BETA CELL BASED THERAPY; CARTILAGE; CELL SHEET TRANSPLANTATION; CELL THERAPY; CELL TRANSPLANTATION; CORNEA; CYTOLOGY; ESOPHAGUS; HEART; HEART DISEASE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LIVER DISEASE; NONHUMAN; PERIODONTAL LIGAMENT; PRIORITY JOURNAL; REGENERATIVE MEDICINE; REVIEW; STEM CELL; TISSUE ENGINEERING; TISSUE GRAFT; TISSUE REPAIR; VASCULARIZATION; CELL SHEET; GLUCOSE BLOOD LEVEL; HEPATOCYTE TRANSPLANTATION; PANCREAS ISLET BETA CELL; CELL ENGINEERING; DIABETES MELLITUS, TYPE 1; HEART DISEASES; LIVER; LIVER DISEASES; MYOBLAST; PANCREAS ISLET TRANSPLANTATION; PHYSIOLOGY; PROCEDURES; REGENERATION; STEM CELL TRANSPLANTATION; TISSUE SCAFFOLD; TRANSPLANTATION;

CELL ENGINEERING; DIABETES MELLITUS, TYPE 1; HEART; HEART DISEASES; HUMANS; ISLETS OF LANGERHANS TRANSPLANTATION; LIVER; LIVER DISEASES; MYOBLASTS; REGENERATION; REGENERATIVE MEDICINE; STEM CELL TRANSPLANTATION; TISSUE SCAFFOLDS;

EID: 84906783700     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.05.024     Document Type: Review

References (135)

1. N. Yamada, T. Okano, H. Sakai, F. Karikusa, Y. Sawasaki, and Y. Sakurai Thermo-responsive polymeric surfaces; control of attachment and detachment of cultured cells Die Makromol. Chem. Rapid Commun. 11 1990 571 576
2. T. Okano, N. Yamada, M. Okuhara, H. Sakai, and Y. Sakurai Mechanism of cell detachment from temperature-modulated, hydrophilic-hydrophobic polymer surfaces Biomaterials 16 1995 297 303
3. A. Kushida, M. Yamato, C. Konno, A. Kikuchi, Y. Sakurai, and T. Okano Decrease in culture temperature releases monolayer endothelial cell sheets together with deposited fibronectin matrix from temperature-responsive culture surfaces J. Biomed. Mater. Res. 45 1999 355 362 (Pubitemid 29196682)
4. M. Yamato, M. Utsumi, A. Kushida, C. Konno, A. Kikuchi, and T. Okano Thermo-responsive culture dishes allow the intact harvest of multilayered keratinocyte sheets without dispase by reducing temperature Tissue Eng. 7 2001 473 480 (Pubitemid 32734778)
5. K. Nishida, M. Yamato, Y. Hayashida, K. Watanabe, K. Yamamoto, E. Adachi, S. Nagai, A. Kikuchi, N. Maeda, H. Watanabe, T. Okano, and Y. Tano Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium N. Engl. J. Med. 351 2004 1187 1196 (Pubitemid 39296306)
6. T. Ohki, M. Yamato, M. Ota, R. Takagi, D. Murakami, M. Kondo, R. Sasaki, H. Namiki, T. Okano, and M. Yamamoto Prevention of esophageal stricture after endoscopic submucosal dissection using tissue-engineered cell sheets Gastroenterology 143 2012 582 588 (e582)
7. Y. Sawa, S. Miyagawa, T. Sakaguchi, T. Fujita, A. Matsuyama, A. Saito, T. Shimizu, and T. Okano Tissue engineered myoblast sheets improved cardiac function sufficiently to discontinue LVAS in a patient with DCM: report of a case Surg. Today 42 2012 181 184
8. M. Sato, M. Yamato, K. Hamahashi, T. Okano, and J. Mochida Articular cartilage regeneration using cell sheet technology Anat. Rec. Hoboken 297 2014 36 43
9. T. Iwata, M. Yamato, H. Tsuchioka, R. Takagi, S. Mukobata, K. Washio, T. Okano, and I. Ishikawa Periodontal regeneration with multi-layered periodontal ligament-derived cell sheets in a canine model Biomaterials 30 2009 2716 2723
10. T. Shimizu, M. Yamato, Y. Isoi, T. Akutsu, T. Setomaru, K. Abe, A. Kikuchi, M. Umezu, and T. Okano Fabrication of pulsatile cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature-responsive cell culture surfaces Circ. Res. 90 2002 e40
11. K. Ohashi, T. Yokoyama, M. Yamato, H. Kuge, H. Kanehiro, M. Tsutsumi, T. Amanuma, H. Iwata, J. Yang, T. Okano, and Y. Nakajima Engineering functional two- and three-dimensional liver systems in vivo using hepatic tissue sheets Nat. Med. 13 2007 880 885 (Pubitemid 47038184)
12. T. Saito, K. Ohashi, R. Utoh, H. Shimizu, K. Ise, H. Suzuki, M. Yamato, T. Okano, and M. Gotoh Reversal of diabetes by the creation of neo-islet tissues into a subcutaneous site using islet cell sheets Transplantation 92 2011 1231 1236
13. M. Kanzaki, M. Yamato, J. Yang, H. Sekine, C. Kohno, R. Takagi, H. Hatakeyama, T. Isaka, T. Okano, and T. Onuki Dynamic sealing of lung air leaks by the transplantation of tissue engineered cell sheets Biomaterials 28 2007 4294 4302 (Pubitemid 47212403)
14. Y. Yaguchi, D. Murakami, M. Yamato, T. Hama, K. Yamamoto, H. Kojima, H. Moriyama, and T. Okano Middle ear mucosal regeneration with three-dimensionally tissue-engineered autologous middle ear cell sheets in rabbit model J. Tissue Eng. Regen. Med. 2013 10.1002/term.1790 [Epub ahead of print]
15. Y. Akiyama, A. Kikuchi, M. Yamato, and T. Okano Ultrathin poly(N-isopropylacrylamide) grafted layer on polystyrene surfaces for cell adhesion/detachment control Langmuir 20 2004 5506 5511
16. K. Fukumori, Y. Akiyama, M. Yamato, J. Kobayashi, K. Sakai, and T. Okano Temperature-responsive glass coverslips with an ultrathin poly(N- isopropylacrylamide) layer Acta Biomater. 5 2009 470 476
17. A. Mizutani, A. Kikuchi, M. Yamato, H. Kanazawa, and T. Okano Preparation of thermoresponsive polymer brush surfaces and their interaction with cells Biomaterials 29 2008 2073 2081
18. K. Nagase, M. Watanabe, A. Kikuchi, M. Yamato, and T. Okano Thermo-responsive polymer brushes as intelligent biointerfaces: preparation via ATRP and characterization Macromol. Biosci. 11 2011 400 409
19. K. Nagase, A. Kimura, T. Shimizu, K. Matsuura, M. Yamato, N. Takeda, and T. Okano Dynamically cell separating thermo-functional biointerfaces with densely packed polymer brushes J. Mater. Chem. 22 2012 19514 19522
20. H. Takahashi, M. Nakayama, M. Yamato, and T. Okano Controlled chain length and graft density of thermoresponsive polymer brushes for optimizing cell sheet harvest Biomacromolecules 11 2010 1991 1999
21. H. Takahashi, N. Matsuzaka, M. Nakayama, A. Kikuchi, M. Yamato, and T. Okano Terminally functionalized thermoresponsive polymer brushes for simultaneously promoting cell adhesion and cell sheet harvest Biomacromolecules 13 2012 253 260
22. N. Matsuzaka, M. Nakayama, H. Takahashi, M. Yamato, A. Kikuchi, and T. Okano Terminal-functionality effect of poly(N-isopropylacrylamide) brush surfaces on temperature-controlled cell adhesion/detachment Biomacromolecules 14 2013 3164 3171
23. M. Nakayama, N. Yamada, Y. Kumashiro, H. Kanazawa, M. Yamato, and T. Okano Thermoresponsive poly(N-isopropylacrylamide)-based block copolymer coating for optimizing cell sheet fabrication Macromol. Biosci. 12 2012 751 760
24. H. Takahashi, M. Nakayama, K. Itoga, M. Yamato, and T. Okano Micropatterned thermoresponsive polymer brush surfaces for fabricating cell sheets with well-controlled orientational structures Biomacromolecules 12 2011 1414 1418
25. Y. Kumashiro, T. Matsunaga, M. Muraoka, N. Tanaka, K. Itoga, J. Kobayashi, Y. Tomiyama, M. Kuroda, T. Shimizu, I. Hashimoto, K. Umemura, M. Yamato, and T. Okano Rate control of cell sheet recovery by incorporating hydrophilic pattern in thermoresponsive cell culture dish J. Biomed. Mater. Res. A 2013 10.1002/jbm.a.34959 [Epub ahead of print]
26. K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872 (Pubitemid 350138099)
27. K. Tatsumi, M. Sugimoto, D. Lillicrap, M. Shima, K. Ohashi, T. Okano, and H. Matsui A novel cell-sheet technology that achieves durable factor VIII delivery in a mouse model of hemophilia A PLoS One 8 2013 e83280
28. E.R. Porrello, A.I. Mahmoud, E. Simpson, J.A. Hill, J.A. Richardson, E.N. Olson, and H.A. Sadek Transient regenerative potential of the neonatal mouse heart Science 331 2011 1078 1080
29. H. Sekine, T. Shimizu, K. Sakaguchi, I. Dobashi, M. Wada, M. Yamato, E. Kobayashi, M. Umezu, and T. Okano In vitro fabrication of functional three-dimensional tissues with perfusable blood vessels Nat. Commun. 4 2013 1399
30. K. Sakaguchi, T. Shimizu, S. Horaguchi, H. Sekine, M. Yamato, M. Umezu, and T. Okano In vitro engineering of vascularized tissue surrogates Sci. Rep. 3 2013 1316
31. S. Makino, K. Fukuda, S. Miyoshi, F. Konishi, H. Kodama, J. Pan, M. Sano, T. Takahashi, S. Hori, H. Abe, J. Hata, A. Umezawa, and S. Ogawa Cardiomyocytes can be generated from marrow stromal cells in vitro J. Clin. Invest. 103 1999 697 705 (Pubitemid 29122423)
32. V. Planat-Benard, C. Menard, M. Andre, M. Puceat, A. Perez, J.M. Garcia-Verdugo, L. Penicaud, and L. Casteilla Spontaneous cardiomyocyte differentiation from adipose tissue stroma cells Circ. Res. 94 2004 223 229 (Pubitemid 38197455)
33. C. Bearzi, M. Rota, T. Hosoda, J. Tillmanns, A. Nascimbene, A. De Angelis, S. Yasuzawa-Amano, I. Trofimova, R.W. Siggins, N. Lecapitaine, S. Cascapera, A.P. Beltrami, D.A. D'Alessandro, E. Zias, F. Quaini, K. Urbanek, R.E. Michler, R. Bolli, J. Kajstura, A. Leri, and P. Anversa Human cardiac stem cells Proc. Natl. Acad. Sci. U. S. A. 104 2007 14068 14073 (Pubitemid 350003336)
34. N. Fukushima, K. Matsuura, H. Akazawa, A. Honda, T. Nagai, T. Takahashi, A. Seki, K.M. Murasaki, T. Shimizu, T. Okano, N. Hagiwara, and I. Komuro A crucial role of activin A-mediated growth hormone suppression in mouse and human heart failure PLoS One 6 2011 e27901
35. H. Sekine, T. Shimizu, I. Dobashi, K. Matsuura, N. Hagiwara, M. Takahashi, E. Kobayashi, M. Yamato, and T. Okano Cardiac cell sheet transplantation improves damaged heart function via superior cell survival in comparison with dissociated cell injection Tissue Eng. A 17 2011 2973 2980
36. K. Matsuura, A. Honda, T. Nagai, N. Fukushima, K. Iwanaga, M. Tokunaga, T. Shimizu, T. Okano, H. Kasanuki, N. Hagiwara, and I. Komuro Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice J. Clin. Invest. 119 2009 2204 2217
37. H. Hamdi, V. Planat-Benard, A. Bel, E. Puymirat, R. Geha, L. Pidial, H. Nematalla, V. Bellamy, P. Bouaziz, S. Peyrard, L. Casteilla, P. Bruneval, A.A. Hagege, O. Agbulut, and P. Menasche Epicardial adipose stem cell sheets results in greater post-infarction survival than intramyocardial injections Cardiovasc. Res. 91 2011 483 491
38. S. Miyagawa, Y. Sawa, S. Sakakida, S. Taketani, H. Kondoh, I.A. Memon, Y. Imanishi, T. Shimizu, T. Okano, and H. Matsuda Tissue cardiomyoplasty using bioengineered contractile cardiomyocyte sheets to repair damaged myocardium: their integration with recipient myocardium Transplantation 80 2005 1586 1595 (Pubitemid 43005870)
39. I.A. Memon, Y. Sawa, N. Fukushima, G. Matsumiya, S. Miyagawa, S. Taketani, S.K. Sakakida, H. Kondoh, A.N. Aleshin, T. Shimizu, T. Okano, and H. Matsuda Repair of impaired myocardium by means of implantation of engineered autologous myoblast sheets J. Thorac. Cardiovasc. Surg. 130 2005 1333 1341 (Pubitemid 41543202)
40. N. Sekiya, G. Matsumiya, S. Miyagawa, A. Saito, T. Shimizu, T. Okano, N. Kawaguchi, N. Matsuura, and Y. Sawa Layered implantation of myoblast sheets attenuates adverse cardiac remodeling of the infarcted heart J. Thorac. Cardiovasc. Surg. 138 2009 985 993
41. H. Kondoh, Y. Sawa, S. Miyagawa, S. Sakakida-Kitagawa, I.A. Memon, N. Kawaguchi, N. Matsuura, T. Shimizu, T. Okano, and H. Matsuda Longer preservation of cardiac performance by sheet-shaped myoblast implantation in dilated cardiomyopathic hamsters Cardiovasc. Res. 69 2006 466 475 (Pubitemid 43098803)
42. T. Hoashi, G. Matsumiya, S. Miyagawa, H. Ichikawa, T. Ueno, M. Ono, A. Saito, T. Shimizu, T. Okano, N. Kawaguchi, N. Matsuura, and Y. Sawa Skeletal myoblast sheet transplantation improves the diastolic function of a pressure-overloaded right heart J. Thorac. Cardiovasc. Surg. 138 2009 460 467
43. H. Hata, G. Matsumiya, S. Miyagawa, H. Kondoh, N. Kawaguchi, N. Matsuura, T. Shimizu, T. Okano, H. Matsuda, and Y. Sawa Grafted skeletal myoblast sheets attenuate myocardial remodeling in pacing-induced canine heart failure model J. Thorac. Cardiovasc. Surg. 132 2006 918 924 (Pubitemid 44415863)
44. S. Miyagawa, A. Saito, T. Sakaguchi, Y. Yoshikawa, T. Yamauchi, Y. Imanishi, N. Kawaguchi, N. Teramoto, N. Matsuura, H. Iida, T. Shimizu, T. Okano, and Y. Sawa Impaired myocardium regeneration with skeletal cell sheets - a preclinical trial for tissue-engineered regeneration therapy Transplantation 90 2010 364 372
45. Y. Miyahara, N. Nagaya, M. Kataoka, B. Yanagawa, K. Tanaka, H. Hao, K. Ishino, H. Ishida, T. Shimizu, K. Kangawa, S. Sano, T. Okano, S. Kitamura, and H. Mori Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction Nat. Med. 12 2006 459 465
46. N. Hida, N. Nishiyama, S. Miyoshi, S. Kira, K. Segawa, T. Uyama, T. Mori, K. Miyado, Y. Ikegami, C. Cui, T. Kiyono, S. Kyo, T. Shimizu, T. Okano, M. Sakamoto, S. Ogawa, and A. Umezawa Novel cardiac precursor-like cells from human menstrual blood-derived mesenchymal cells Stem Cells 26 2008 1695 1704
47. Y. Imanishi, S. Miyagawa, N. Maeda, S. Fukushima, S. Kitagawa-Sakakida, T. Daimon, A. Hirata, T. Shimizu, T. Okano, I. Shimomura, and Y. Sawa Induced adipocyte cell-sheet ameliorates cardiac dysfunction in a mouse myocardial infarction model: a novel drug delivery system for heart failure Circulation 124 2011 S10 S17
48. H. Sekine, T. Shimizu, K. Hobo, S. Sekiya, J. Yang, M. Yamato, H. Kurosawa, E. Kobayashi, and T. Okano Endothelial cell coculture within tissue-engineered cardiomyocyte sheets enhances neovascularization and improves cardiac function of ischemic hearts Circulation 118 2008 S145 S152
49. H. Kobayashi, T. Shimizu, M. Yamato, K. Tono, H. Masuda, T. Asahara, H. Kasanuki, and T. Okano Fibroblast sheets co-cultured with endothelial progenitor cells improve cardiac function of infarcted hearts J. Artif. Organs 11 2008 141 147
50. A. Bel, V. Planat-Bernard, A. Saito, L. Bonnevie, V. Bellamy, L. Sabbah, L. Bellabas, B. Brinon, V. Vanneaux, P. Pradeau, S. Peyrard, J. Larghero, J. Pouly, P. Binder, S. Garcia, T. Shimizu, Y. Sawa, T. Okano, P. Bruneval, M. Desnos, A.A. Hagege, L. Casteilla, M. Puceat, and P. Menasche Composite cell sheets: a further step toward safe and effective myocardial regeneration by cardiac progenitors derived from embryonic stem cells Circulation 122 2010 S118 S123
51. H. Masumoto, T. Matsuo, K. Yamamizu, H. Uosaki, G. Narazaki, S. Katayama, A. Marui, T. Shimizu, T. Ikeda, T. Okano, R. Sakata, and J.K. Yamashita Pluripotent stem cell-engineered cell sheets reassembled with defined cardiovascular populations ameliorate reduction in infarct heart function through cardiomyocyte-mediated neovascularization Stem Cells 30 2012 1196 1205
52. M. Kawamura, S. Miyagawa, K. Miki, A. Saito, S. Fukushima, T. Higuchi, T. Kawamura, T. Kuratani, T. Daimon, T. Shimizu, T. Okano, and Y. Sawa Feasibility, safety, and therapeutic efficacy of human induced pluripotent stem cell-derived cardiomyocyte sheets in a porcine ischemic cardiomyopathy model Circulation 126 2012 S29 S37
53. M. Sano, T. Minamino, H. Toko, H. Miyauchi, M. Orimo, Y. Qin, H. Akazawa, K. Tateno, Y. Kayama, M. Harada, I. Shimizu, T. Asahara, H. Hamada, S. Tomita, J.D. Molkentin, Y. Zou, and I. Komuro p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload Nature 446 2007 444 448 (Pubitemid 46474597)
54. D.A. Bull, S.H. Bailey, J.J. Rentz, J.S. Zebrack, M. Lee, S.E. Litwin, and S.W. Kim Effect of Terplex/VEGF-165 gene therapy on left ventricular function and structure following myocardial infarction. VEGF gene therapy for myocardial infarction J. Control. Release 93 2003 175 181 (Pubitemid 37421358)
55. J. Kastrup, E. Jorgensen, A. Ruck, K. Tagil, D. Glogar, W. Ruzyllo, H.E. Botker, D. Dudek, V. Drvota, B. Hesse, L. Thuesen, P. Blomberg, M. Gyongyosi, and C. Sylven Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris. A randomized double-blind placebo-controlled study: the Euroinject One trial J. Am. Coll. Cardiol. 45 2005 982 988 (Pubitemid 40432426)
56. D.J. Stewart, M.J. Kutryk, D. Fitchett, M. Freeman, N. Camack, Y. Su, A. Della Siega, L. Bilodeau, J.R. Burton, G. Proulx, and S. Radhakrishnan VEGF gene therapy fails to improve perfusion of ischemic myocardium in patients with advanced coronary disease: results of the NORTHERN trial Mol. Ther. 17 2009 1109 1115
57. M. Perez-Ilzarbe, O. Agbulut, B. Pelacho, C. Ciorba, E. San Jose-Eneriz, M. Desnos, A.A. Hagege, P. Aranda, E.J. Andreu, P. Menasche, and F. Prosper Characterization of the paracrine effects of human skeletal myoblasts transplanted in infarcted myocardium Eur. J. Heart Fail. 10 2008 1065 1072
58. R.S. Kerbel Tumor angiogenesis N. Engl. J. Med. 358 2008 2039 2049 (Pubitemid 351656458)
59. H. Nakagami, R. Morishita, K. Yamamoto, Y. Taniyama, M. Aoki, K. Matsumoto, T. Nakamura, Y. Kaneda, M. Horiuchi, and T. Ogihara Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and AKT in endothelial cells Hypertension 37 2001 581 586 (Pubitemid 32199031)
60. K. Urbanek, M. Rota, S. Cascapera, C. Bearzi, A. Nascimbene, A. De Angelis, T. Hosoda, S. Chimenti, M. Baker, F. Limana, D. Nurzynska, D. Torella, F. Rotatori, R. Rastaldo, E. Musso, F. Quaini, A. Leri, J. Kajstura, and P. Anversa Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival Circ. Res. 97 2005 663 673 (Pubitemid 41416335)
61. J. Yamaguchi, K.F. Kusano, O. Masuo, A. Kawamoto, M. Silver, S. Murasawa, M. Bosch-Marce, H. Masuda, D.W. Losordo, J.M. Isner, and T. Asahara Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization Circulation 107 2003 1322 1328 (Pubitemid 36314418)
62. Y. Shudo, S. Miyagawa, H. Ohkura, S. Fukushima, A. Saito, M. Shiozaki, N. Kawaguchi, N. Matsuura, T. Shimizu, T. Okano, A. Matsuyama, and Y. Sawa Addition of mesenchymal stem cells enhances the therapeutic effects of skeletal myoblast cell-sheet transplantation in a rat ischemic cardiomyopathy model Tissue Eng. A 20 3-4 2014 728 739
63. Y. Shudo, S. Miyagawa, S. Fukushima, A. Saito, T. Shimizu, T. Okano, and Y. Sawa Novel regenerative therapy using cell-sheet covered with omentum flap delivers a huge number of cells in a porcine myocardial infarction model J. Thorac. Cardiovasc. Surg. 142 2011 1188 1196
64. J.S. Burchfield, M. Xie, and J.A. Hill Pathological ventricular remodeling: mechanisms: part 1 of 2 Circulation 128 2013 388 400
65. N.G. Frangogiannis Regulation of the inflammatory response in cardiac repair Circ. Res. 110 2012 159 173
66. E.S. Chung, M. Packer, K.H. Lo, A.A. Fasanmade, and J.T. Willerson Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial Circulation 107 2003 3133 3140 (Pubitemid 36793081)
67. D.L. Mann, J.J. McMurray, M. Packer, K. Swedberg, J.S. Borer, W.S. Colucci, J. Djian, H. Drexler, A. Feldman, L. Kober, H. Krum, P. Liu, M. Nieminen, L. Tavazzi, D.J. van Veldhuisen, A. Waldenstrom, M. Warren, A. Westheim, F. Zannad, and T. Fleming Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL) Circulation 109 2004 1594 1602 (Pubitemid 38451714)
68. W.A. Ray, C.M. Stein, K. Hall, J.R. Daugherty, and M.R. Griffin Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease: an observational cohort study Lancet 359 2002 118 123 (Pubitemid 34112540)
69. L. Gullestad, H. Aass, J.G. Fjeld, L. Wikeby, A.K. Andreassen, H. Ihlen, S. Simonsen, J. Kjekshus, S. Nitter-Hauge, T. Ueland, E. Lien, S.S. Froland, and P. Aukrust Immunomodulating therapy with intravenous immunoglobulin in patients with chronic heart failure Circulation 103 2001 220 225 (Pubitemid 32095406)
70. K. Le Blanc, F. Frassoni, L. Ball, F. Locatelli, H. Roelofs, I. Lewis, E. Lanino, B. Sundberg, M.E. Bernardo, M. Remberger, G. Dini, R.M. Egeler, A. Bacigalupo, W. Fibbe, and O. Ringden Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study Lancet 371 2008 1579 1586 (Pubitemid 351626841)
71. K. Matsuura, S. Masuda, Y. Haraguchi, N. Yasuda, T. Shimizu, N. Hagiwara, P.W. Zandstra, and T. Okano Creation of mouse embryonic stem cell-derived cardiac cell sheets Biomaterials 32 2011 7355 7362
72. K. Matsuura, M. Wada, T. Shimizu, Y. Haraguchi, F. Sato, K. Sugiyama, K. Konishi, Y. Shiba, H. Ichikawa, A. Tachibana, U. Ikeda, M. Yamato, N. Hagiwara, and T. Okano Creation of human cardiac cell sheets using pluripotent stem cells Biochem. Biophys. Res. Commun. 425 2012 321 327
73. M. Kawamura, S. Miyagawa, S. Fukushima, A. Saito, K. Miki, E. Ito, N. Sougawa, T. Kawamura, T. Daimon, T. Shimizu, T. Okano, K. Toda, and Y. Sawa Enhanced survival of transplanted human induced pluripotent stem cell-derived cardiomyocytes by the combination of cell sheets with the pedicled omental flap technique in a porcine heart Circulation 128 2013 S87 S94
74. J.P. Palmer, G.A. Fleming, C.J. Greenbaum, K.C. Herold, L.D. Jansa, H. Kolb, J.M. Lachin, K.S. Polonsky, P. Pozzilli, J.S. Skyler, and M.W. Steffes C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001 Diabetes 53 2004 250 264 (Pubitemid 38044724)
75. H. Egawa, K. Tanabe, N. Fukushima, H. Date, A. Sugitani, and H. Haga Current status of organ transplantation in Japan Am. J. Transplant. 12 2012 523 530
76. I.J. Fox, and J.R. Chowdhury Hepatocyte transplantation Am. J. Transplant. 4 Suppl. 6 2004 7 13 (Pubitemid 38282274)
77. R.A. Fisher, and S.C. Strom Human hepatocyte transplantation: worldwide results Transplantation 82 2006 441 449 (Pubitemid 44290247)
78. A. Dhawan, J. Puppi, R.D. Hughes, and R.R. Mitry Human hepatocyte transplantation: current experience and future challenges Nat. Rev. Gastroenterol. Hepatol. 7 2010 288 298
79. A. Dhawan, S.C. Strom, E. Sokal, and I.J. Fox Human hepatocyte transplantation Methods Mol. Biol. 640 2010 525 534
80. S. Kasai, M. Sawa, K. Kondoh, H. Ebata, and M. Mito Intrasplenic hepatocyte transplantation in mammals Transplant. Proc. 19 1987 992 994 (Pubitemid 17026723)
81. K.P. Ponder, S. Gupta, F. Leland, G. Darlington, M. Finegold, J. DeMayo, F.D. Ledley, J.R. Chowdhury, and S.L. Woo Mouse hepatocytes migrate to liver parenchyma and function indefinitely after intrasplenic transplantation Proc. Natl. Acad. Sci. U. S. A. 88 1991 1217 1221 (Pubitemid 21916196)
82. M. Attaran, A. Schneider, C. Grote, C. Zwiens, P. Flemming, K.F. Gratz, A. Jochheim, M.J. Bahr, M.P. Manns, and M. Ott Regional and transient ischemia/reperfusion injury in the liver improves therapeutic efficacy of allogeneic intraportal hepatocyte transplantation in low-density lipoprotein receptor deficient Watanabe rabbits J. Hepatol. 41 2004 837 844 (Pubitemid 39434315)
83. J. Meyburg, F. Hoerster, J. Schmidt, J. Poeschl, G.F. Hoffmann, and J.P. Schenk Monitoring of intraportal liver cell application in children Cell Transplant. 19 2010 629 638
84. G. Gabelein, A.K. Nussler, F. Morgott, Y. Ping, N. Nussler, P. Neuhaus, and M. Glanemann Intrasplenic or subperitoneal hepatocyte transplantation to increase survival after surgically induced hepatic failure? Eur. Surg. Res. 41 2008 253 259
85. Y. Goto, K. Ohashi, R. Utoh, M. Yamamoto, and T. Okano Hepatocyte transplantation through the hepatic vein: a new route of cell transplantation to the liver Cell Transplant. 20 2011 1259 1270
86. I.J. Fox, J.R. Chowdhury, S.S. Kaufman, T.C. Goertzen, N.R. Chowdhury, P.I. Warkentin, K. Dorko, B.V. Sauter, and S.C. Strom Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation N. Engl. J. Med. 338 1998 1422 1426 (Pubitemid 28221983)
87. J. Puppi, N. Tan, R.R. Mitry, R.D. Hughes, S. Lehec, G. Mieli-Vergani, J. Karani, M.P. Champion, N. Heaton, R. Mohamed, and A. Dhawan Hepatocyte transplantation followed by auxiliary liver transplantation - a novel treatment for ornithine transcarbamylase deficiency Am. J. Transplant. 8 2008 452 457
88. A. Dhawan, R.R. Mitry, R.D. Hughes, S. Lehec, C. Terry, S. Bansal, R. Arya, J.J. Wade, A. Verma, N.D. Heaton, M. Rela, and G. Mieli-Vergani Hepatocyte transplantation for inherited factor VII deficiency Transplantation 78 2004 1812 1814 (Pubitemid 40041650)
89. M. Muraca, G. Gerunda, D. Neri, M.T. Vilei, A. Granato, P. Feltracco, M. Meroni, G. Giron, and A.B. Burlina Hepatocyte transplantation as a treatment for glycogen storage disease type 1a Lancet 359 2002 317 318 (Pubitemid 34119297)
90. R.D. Hughes, R.R. Mitry, and A. Dhawan Current status of hepatocyte transplantation Transplantation 93 2012 342 347
91. K. Asonuma, J.C. Gilbert, J.E. Stein, T. Takeda, and J.P. Vacanti Quantitation of transplanted hepatic mass necessary to cure the Gunn rat model of hyperbilirubinemia J. Pediatr. Surg. 27 1992 298 301
92. B. Joseph, H. Malhi, K.K. Bhargava, C.J. Palestro, R.S. McCuskey, and S. Gupta Kupffer cells participate in early clearance of syngeneic hepatocytes transplanted in the rat liver Gastroenterology 123 2002 1677 1685 (Pubitemid 35231667)
93. S. Gupta, P. Rajvanshi, R. Sokhi, S. Slehria, A. Yam, A. Kerr, and P.M. Novikoff Entry and integration of transplanted hepatocytes in rat liver plates occur by disruption of hepatic sinusoidal endothelium Hepatology 29 1999 509 519 (Pubitemid 29088456)
94. K. Ohashi, K. Tatsumi, C. Tateno, M. Kataoka, R. Utoh, K. Yoshizato, and T. Okano Liver tissue engineering utilizing hepatocytes propagated in mouse livers in vivo Cell Transplant. 21 2012 429 436
95. M.F. Brown, T.P. Gratton, and J.A. Stuart Metabolic rate does not scale with body mass in cultured mammalian cells Am. J. Physiol. Regul. Integr. Comp. Physiol. 292 2007 R2115 R2121
96. S. Kidambi, R.S. Yarmush, E. Novik, P. Chao, M.L. Yarmush, and Y. Nahmias Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance Proc. Natl. Acad. Sci. U. S. A. 106 2009 15714 15719
97. B.P. Dranka, B.G. Hill, and V.M. Darley-Usmar Mitochondrial reserve capacity in endothelial cells: the impact of nitric oxide and reactive oxygen species Free Radic. Biol. Med. 48 2010 905 914
98. K. Ohashi, J.M. Waugh, M.D. Dake, T. Yokoyama, H. Kuge, Y. Nakajima, M. Yamanouchi, H. Naka, A. Yoshioka, and M.A. Kay Liver tissue engineering at extrahepatic sites in mice as a potential new therapy for genetic liver diseases Hepatology 41 2005 132 140 (Pubitemid 40066391)
99. J. Gitschier, W.I. Wood, T.M. Goralka, K.L. Wion, E.Y. Chen, D.H. Eaton, G.A. Vehar, D.J. Capon, and R.M. Lawn Characterization of the human factor VIII gene Nature 312 1984 326 330 (Pubitemid 15209308)
100. K. Tatsumi, K. Ohashi, M. Shima, Y. Nakajima, T. Okano, and A. Yoshioka Therapeutic effects of hepatocyte transplantation on hemophilia B Transplantation 86 2008 167 170
101. K. Ohashi, K. Tatsumi, R. Utoh, S. Takagi, M. Shima, and T. Okano Engineering liver tissues under the kidney capsule site provides therapeutic effects to hemophilia B mice Cell Transplant. 19 2010 807 813
102. Y. Lin, D.J. Weisdorf, A. Solovey, and R.P. Hebbel Origins of circulating endothelial cells and endothelial outgrowth from blood J. Clin. Invest. 105 2000 71 77 (Pubitemid 30036389)
103. J. Martin-Ramirez, M. Hofman, M. van den Biggelaar, R.P. Hebbel, and J. Voorberg Establishment of outgrowth endothelial cells from peripheral blood Nat. Protoc. 7 2012 1709 1715
104. H. Matsui, M. Shibata, B. Brown, A. Labelle, C. Hegadorn, C. Andrews, R.P. Hebbel, J. Galipeau, C. Hough, and D. Lillicrap Ex vivo gene therapy for hemophilia A that enhances safe delivery and sustained in vivo factor VIII expression from lentivirally engineered endothelial progenitors Stem Cells 25 2007 2660 2669 (Pubitemid 47582759)
105. G.C. Webb, M.S. Akbar, C. Zhao, and D.F. Steiner Expression profiling of pancreatic beta cells: glucose regulation of secretory and metabolic pathway genes Proc. Natl. Acad. Sci. U. S. A. 97 2000 5773 5778 (Pubitemid 30367474)
106. V. Poitout, D. Hagman, R. Stein, I. Artner, R.P. Robertson, and J.S. Harmon Regulation of the insulin gene by glucose and fatty acids J. Nutr. 136 2006 873 876
107. M. McCall, and A.M. Shapiro Update on islet transplantation Cold Spring Harb. Perspect. Med. 2 2012 a007823
108. U. Pedersen-Bjergaard, S. Pramming, S.R. Heller, T.M. Wallace, A.K. Rasmussen, H.V. Jorgensen, D.R. Matthews, P. Hougaard, and B. Thorsteinsson Severe hypoglycaemia in 1076 adult patients with type 1 diabetes: influence of risk markers and selection Diabetes Metab. Res. Rev. 20 2004 479 486 (Pubitemid 40028649)
109. X. Liu, S. Matsumoto, T. Okitsu, Y. Iwanaga, H. Noguchi, Y. Yonekawa, H. Nagata, H. Kamiya, M. Ueda, N. Hatanaka, S. Miyakawa, N. Kobayashi, and C. Song Analysis of donor- and isolation-related variables from non-heart-beating donors (NHBDs) using the Kyoto islet isolation method Cell Transplant. 17 2008 649 656
110. A.M. Shapiro Islet transplantation in type 1 diabetes: ongoing challenges, refined procedures, and long-term outcome Rev. Diabetes Stud. 9 2012 385 406
111. A.M. Shapiro, J.R. Lakey, E.A. Ryan, G.S. Korbutt, E. Toth, G.L. Warnock, N.M. Kneteman, and R.V. Rajotte Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen N. Engl. J. Med. 343 2000 230 238 (Pubitemid 30490390)
112. R. Bottino, L.A. Fernandez, C. Ricordi, R. Lehmann, M.F. Tsan, R. Oliver, and L. Inverardi Transplantation of allogeneic islets of Langerhans in the rat liver: effects of macrophage depletion on graft survival and microenvironment activation Diabetes 47 1998 316 323 (Pubitemid 28104190)
113. L. Moberg, H. Johansson, A. Lukinius, C. Berne, A. Foss, R. Kallen, O. Ostraat, K. Salmela, A. Tibell, G. Tufveson, G. Elgue, K. Nilsson Ekdahl, O. Korsgren, and B. Nilsson Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation Lancet 360 2002 2039 2045 (Pubitemid 36026584)
114. P. Soon-Shiong, R.E. Heintz, N. Merideth, Q.X. Yao, Z. Yao, T. Zheng, M. Murphy, M.K. Moloney, M. Schmehl, and M. Harris et al. Insulin independence in a type 1 diabetic patient after encapsulated islet transplantation Lancet 343 1994 950 951 (Pubitemid 24117231)
115. Y. Sun, X. Ma, D. Zhou, I. Vacek, and A.M. Sun Normalization of diabetes in spontaneously diabetic cynomologus monkeys by xenografts of microencapsulated porcine islets without immunosuppression J. Clin. Invest. 98 1996 1417 1422 (Pubitemid 26322067)
116. H. Ohgawara Strategies for immunoisolation in islet transplantation: challenges for the twenty-first century J. Hepato-Biliary-Pancreat. Surg. 7 2000 374 379
117. W. Wang, Y. Gu, Y. Tabata, M. Miyamoto, H. Hori, N. Nagata, M. Touma, A.N. Balamurugan, Y. Kawakami, M. Nozawa, and K. Inoue Reversal of diabetes in mice by xenotransplantation of a bioartificial pancreas in a prevascularized subcutaneous site Transplantation 73 2002 122 129 (Pubitemid 34094698)
118. A. Pileggi, R.D. Molano, C. Ricordi, E. Zahr, J. Collins, R. Valdes, and L. Inverardi Reversal of diabetes by pancreatic islet transplantation into a subcutaneous, neovascularized device Transplantation 81 2006 1318 1324 (Pubitemid 43804553)
119. J.I. Lee, R. Nishimura, H. Sakai, N. Sasaki, and T. Kenmochi A newly developed immunoisolated bioartificial pancreas with cell sheet engineering Cell Transplant. 17 2008 51 59 (Pubitemid 351551380)
120. B. Ludwig, A. Rotem, J. Schmid, G.C. Weir, C.K. Colton, M.D. Brendel, T. Neufeld, N.L. Block, K. Yavriyants, A. Steffen, S. Ludwig, T. Chavakis, A. Reichel, D. Azarov, B. Zimermann, S. Maimon, M. Balyura, T. Rozenshtein, N. Shabtay, P. Vardi, K. Bloch, P. de Vos, A.V. Schally, S.R. Bornstein, and U. Barkai Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist Proc. Natl. Acad. Sci. U. S. A. 109 2012 5022 5027
121. N.E. Davis, L.N. Beenken-Rothkopf, A. Mirsoian, N. Kojic, D.L. Kaplan, A.E. Barron, and M.J. Fontaine Enhanced function of pancreatic islets co-encapsulated with ECM proteins and mesenchymal stromal cells in a silk hydrogel Biomaterials 33 2012 6691 6697
122. C.E. Ellis, E. Suuronen, T. Yeung, K. Seeberger, and G.S. Korbutt Bioengineering a highly vascularized matrix for the ectopic transplantation of islets Islets 5 2013
123. U. Barkai, G.C. Weir, C.K. Colton, B. Ludwig, S.R. Bornstein, M.D. Brendel, T. Neufeld, C. Bremer, A. Leon, Y. Evron, K. Yavriyants, D. Azarov, B. Zimermann, S. Maimon, N. Shabtay, M. Balyura, T. Rozenshtein, P. Vardi, K. Bloch, P. de Vos, and A. Rotem Enhanced oxygen supply improves islet viability in a new bioartificial pancreas Cell Transplant. 22 2013 1463 1476
124. S. Veriter, P. Gianello, and D. Dufrane Bioengineered sites for islet cell transplantation Curr. Diabetes Rep. 13 2013 745 755
125. H. Shimizu, K. Ohashi, R. Utoh, K. Ise, M. Gotoh, M. Yamato, and T. Okano Bioengineering of a functional sheet of islet cells for the treatment of
126. S. Kantengwa, D. Baetens, K. Sadoul, C.A. Buck, P.A. Halban, and D.G. Rouiller Identification and characterization of alpha 3 beta 1 integrin on primary and transformed rat islet cells Exp. Cell Res. 237 1997 394 402 (Pubitemid 28027934)
127. D. Bosco, P. Meda, P.A. Halban, and D.G. Rouiller Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro: role of alpha6beta1 integrin Diabetes 49 2000 233 243 (Pubitemid 30071002)
128. G. Parnaud, E. Hammar, D.G. Rouiller, M. Armanet, P.A. Halban, and D. Bosco Blockade of beta1 integrin-laminin-5 interaction affects spreading and insulin secretion of rat beta-cells attached on extracellular matrix Diabetes 55 2006 1413 1420 (Pubitemid 44195381)
129. H. Shimizu, K. Ohashi, T. Saito, R. Utoh, K. Ise, M. Yamato, T. Okano, and M. Gotoh Topographical arrangement of alpha- and beta-cells within neo-islet tissues engineered by islet cell sheet transplantation in mice Transplant. Proc. 45 2013 1881 1884
130. V.F. Duvivier-Kali, A. Omer, R.J. Parent, J.J. O'Neil, and G.C. Weir Complete protection of islets against allorejection and autoimmunity by a simple barium-alginate membrane Diabetes 50 2001 1698 1705 (Pubitemid 33641585)
131. J. Schrezenmeir, J. Kirchgessner, L. Gero, L.A. Kunz, J. Beyer, and W. Mueller-Klieser Effect of microencapsulation on oxygen distribution in islets organs Transplantation 57 1994 1308 1314 (Pubitemid 24145573)
132. C. Kampf, G. Mattsson, and P.O. Carlsson Size-dependent revascularization of transplanted pancreatic islets Cell Transplant. 15 2006 205 209 (Pubitemid 43726196)
133. R. Lehmann, R.A. Zuellig, P. Kugelmeier, P.B. Baenninger, W. Moritz, A. Perren, P.A. Clavien, M. Weber, and G.A. Spinas Superiority of small islets in human islet transplantation Diabetes 56 2007 594 603 (Pubitemid 46348450)
134. M. Egami, Y. Haraguchi, T. Shimizu, M. Yamato, and T. Okano Latest status of the clinical and industrial applications of cell sheet engineering and regenerative medicine Arch. Pharm. Res. 37 2014 96 106
135. H. Kubo, T. Shioyama, M. Oura, A. Suzuki, T. Ogawa, H. Makino, S. Takeda, M. Kino-Oka, T. Shimizu, T. Okano, and S. Yamamori Development of automated 3-dimensional tissue fabrication system tissue factory - automated cell isolation from tissue for regenerative medicine Conf. Proc. IEEE Eng. Med. Biol. Soc. 2013 2013 358 361