In vitro fabrication of functional three-dimensional tissues with perfusable blood vessels

Nature Communications

Volumn 4, Issue , 2013, Pages

  Sekine, Hidekazu ^a   Shimizu, Tatsuya ^a   Sakaguchi, Katsuhisa ^b   Dobashi, Izumi ^a   Wada, Masanori ^c   Yamato, Masayuki ^a   Kobayashi, Eiji ^d   Umezu, Mitsuo ^b   Okano, Teruo ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b WASEDA UNIVERSITY   (Japan)

^c ABLE Corporation   (Japan)

^d JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOENGINEERING; BIOREACTOR; BLOOD; THREE-DIMENSIONAL MODELING;

ANGIOGENESIS; ARTICLE; CAPILLARY; CELLS; COCULTURE; ENDOTHELIUM CELL; HEART; HEART BLOOD VESSEL; HEART MUSCLE CELL; IN VITRO STUDY; NANOFABRICATION; SCALE UP; SURVIVAL; TISSUE ENGINEERING; TISSUE PERFUSION; ANIMAL; BIOREACTOR; BLOOD VESSEL; CELL SURVIVAL; CYTOLOGY; FISCHER 344 RAT; FLUORESCENCE MICROSCOPY; GROWTH, DEVELOPMENT AND AGING; MALE; METHODOLOGY; PERFUSION; RAT; SPRAGUE DAWLEY RAT; TISSUE SURVIVAL; TRANSPLANTATION;

ANIMALS; BIOREACTORS; BLOOD VESSELS; CELL SURVIVAL; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; MALE; MICROSCOPY, FLUORESCENCE; NEOVASCULARIZATION, PHYSIOLOGIC; PERFUSION; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; TISSUE ENGINEERING; TISSUE SURVIVAL;

MLCS; MLOWN;

EID: 84879188211     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2406     Document Type: Article

References (29)

1. Lango, A.H. et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 467, 832-838 (2010).
2. Langer, R. & Vacanti, J. P. Tissue engineering. Science 260, 920-926 (1993). (Pubitemid 23209960)
3. Cao, Y., Vacanti, J. P., Paige, K. T., Upton, J. & Vacanti, C. A. Transplantation of chondrocytes utilizing a polymer-cell construct to produce tissue-engineered cartilage in the shape of a human ear. Plast. Reconstr. Surg. 100, 297-302 (1997).
4. Kirsner, R. S., Falanga, V. & Eaglstein, W. H. The development of bioengineered skin. Trends Biotechnol. 16, 246-249 (1998). (Pubitemid 28255387)
5. Brittberg, M. et al. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N. Engl. J. Med. 331, 889-895 (1994). (Pubitemid 24299869)
6. Shin'oka, T., Imai, Y. & Ikada, Y. Transplantation of a tissue-engineered pulmonary artery. N. Engl. J. Med. 344, 532-533 (2001).
7. Okano, T., Yamada, N., Sakai, H. & Sakurai, Y. A novel recovery system for cultured cells using plasma-treated polystyrene dishes grafted with poly(N-isopropylacrylamide). J. Biomed. Mater. Res. 27, 1243-1251 (1993). (Pubitemid 23289647)
8. Shimizu, T., Yamato, M., Kikuchi, A. & Okano, T. Cell sheet engineering for myocardial tissue reconstruction. Biomaterials 24, 2309-2316 (2003). (Pubitemid 36434050)
9. Nishida, K. et al. Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium. N Engl. J. Med. 351, 1187-1196 (2004). (Pubitemid 39296306)
10. Ohki, T. et al. Treatment of oesophageal ulcerations using endoscopic transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets in a canine model. Gut 55, 1704-1710 (2006). (Pubitemid 44893566)
11. Sawa, Y. et al. Tissue engineered myoblast sheets improved cardiac function sufficiently to discontinue LVAS in a patient with DCM: report of a case. Surg. Today 42, 181-184 (2012).
12. Shimizu, T. et al. Fabrication of pulsatile cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature- responsive cell culture surfaces. Circ. Res. 90, e40 (2002).
13. Novosel, E. C., Kleinhans, C. & Kluger, P. J. Vascularization is the key challenge in tissue engineering. Adv. Drug Deliv. Rev. 63, 300-311 (2011).
14. Sekiya, S., Shimizu, T., Yamato, M., Kikuchi, A. & Okano, T. Bioengineered cardiac cell sheet grafts have intrinsic angiogenic potential. Biochem. Biophys. Res. Commun. 341, 573-582 (2006). (Pubitemid 43152142)
15. Sekine, H. et al. Endothelial cell coculture within tissue-engineered cardiomyocyte sheets enhances neovascularization and improves cardiac function of ischemic hearts. Circulation 118, S145-S152 (2008).
16. Yang, J. et al. Reconstruction of functional tissues with cell sheet engineering. Biomaterials 28, 5033-5043 (2007). (Pubitemid 47488500)
17. Cao, R. et al. Comparative evaluation of FGF-2-, VEGF-A-, and VEGF-C-induced angiogenesis, lymphangiogenesis, vascular fenestrations, and permeability. Circ. Res. 94, 664-670 (2004). (Pubitemid 38387750)
18. Shimizu, T. et al. Polysurgery of cell sheet grafts overcomes diffusion limits to produce thick, vascularized myocardial tissues. FASEB J. 20, 708-710 (2006). (Pubitemid 46671189)
19. Xiu, D. et al. Simplified method of heterotopic rat heart transplantation using the cuff technique: application to sublethal dose protocol of methotrexate on allograft survival. Microsurgery 21, 16-21 (2001). (Pubitemid 32158592)
20. Kushida, A. et al. Decrease in culture temperature releases monolayer endothelial cell sheets together with deposited fibronectin matrix from temperature-responsive culture surfaces. J. Biomed. Mater. Res. 45, 355-362 (1999). (Pubitemid 29196682)
21. Shimizu, T. et al. Electrically communicating three-dimensional cardiac tissue mimic fabricated by layered cultured cardiomyocyte sheets. J. Biomed. Mater. Res. 60, 110-117 (2002). (Pubitemid 34126992)
22. Haraguchi, Y., Shimizu, T., Yamato, M., Kikuchi, A. & Okano, T. Electrical coupling of cardiomyocyte sheets occurs rapidly via functional gap junction formation. Biomaterials 27, 4765-4774 (2006). (Pubitemid 43849973)
23. Sasagawa, T. et al. Design of prevascularized three-dimensional cell-dense tissues using a cell sheet stacking manipulation technology. Biomaterials 31, 1646-1654 (2010).
24. Kaihara, S. et al. Silicon micromachining to tissue engineer branched vascular channels for liver fabrication. Tissue Eng. 6, 105-117 (2000). (Pubitemid 30227167)
25. Neumann, T., Nicholson, B. S. & Sanders, J. E. Tissue engineering of perfused microvessels. Microvasc. Res. 66, 59-67 (2003). (Pubitemid 36773171)
26. Ott, H. C. et al. Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart. Nat. Med. 14, 213-221 (2008). (Pubitemid 351214548)
27. Chang, E. I. et al. Tissue engineering using autologous microcirculatory beds as vascularized bioscaffolds. FASEB J. 23, 906-915 (2009).
28. Keyaerts, M. et al. Dynamic bioluminescence imaging for quantitative tumour burden assessment using IV or IP administration of D:-luciferin: effect on intensity, time kinetics and repeatability of photon emission. Eur. J. Nucl. Med. Mol. Imaging 35, 999-1007 (2008).
29. Matsuura, K. et al. Creation of human cardiac cell sheets using pluripotent stem cells. Biochem. Biophys. Res. Commun. 425, 321-327 (2012).