Bioengineering of a functional sheet of islet cells for the treatment of diabetes mellitus

Biomaterials

Volumn 30, Issue 30, 2009, Pages 5943-5949

  Shimizu, Hirofumi ^a   Ohashi, Kazuo ^b   Utoh, Rie ^b   Ise, Kazuya ^a   Gotoh, Mitsukazu ^a   Yamato, Masayuki ^b   Okano, Teruo ^b  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Cell sheet; Islet transplantation; Laminin 5; Monolayer culture

Indexed keywords

ALTERNATIVE METHODS; CELL SHEET; CELL-BASED THERAPY; CULTURE DISHES; CULTURE TEMPERATURE; DIABETES MELLITUS; EXTRACELLULAR MATRIX PROTEIN; FUNCTIONAL ACTIVITIES; HISTOLOGICAL EXAMINATION; IN-VIVO; INSULIN SECRETION; ISLET TRANSPLANTATION; LAMININ; LAMININ-5; MONOLAYER CULTURE; PANCREATIC ISLET CELLS; TEMPERATURE-RESPONSIVE; TISSUE SHEETS;

CELL MEMBRANES; HARVESTING; INSULIN; MONOLAYERS; RATS; TISSUE ENGINEERING;

CELL CULTURE;

GLUCAGON; INSULIN; KALININ; MATRIX PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOENGINEERING; CELL ACTIVITY; CELL CULTURE; CELL FUNCTION; CELL SURVIVAL; CELL SUSPENSION; CELL THERAPY; CONTROLLED STUDY; DIABETES MELLITUS; EXTRACELLULAR MATRIX; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; LEWIS RAT; MALE; MONOLAYER CULTURE; NONHUMAN; PANCREAS ISLET CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; RAT; TEMPERATURE SENSITIVITY; TISSUE ENGINEERING;

ANIMALS; CELL ADHESION MOLECULES; CELL TRANSPLANTATION; DIABETES MELLITUS, EXPERIMENTAL; EXTRACELLULAR MATRIX; GLUCAGON; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICROSCOPY, ELECTRON; RATS; RATS, INBRED LEW; TEMPERATURE; TIME FACTORS;

RATTUS;

EID: 69249230764     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.07.042     Document Type: Article

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