Regional and transient ischemia/reperfusion injury in the liver improves therapeutic efficacy of allogeneic intraportal hepatocyte transplantation in low-density lipoprotein receptor deficient Watanabe rabbits

Journal of Hepatology

Volumn 41, Issue 5, 2004, Pages 837-844

  Attaran, Masoumeh ^a   Schneider, Andrea ^a   Grote, Christiane ^a   Zwiens, Caroline ^a   Flemming, Peer ^b   Gratz, Klaus F ^b   Jochheim, Andrea ^a   Bahr, Matthias J ^a   Manns, Michael P ^a   Ott, Michael ^a  

^a Inst of Exp Internal Medicine   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Hepatocyte transplantation; Hereditary liver disease; Port implantation; Rabbit model; Regeneration stimulus

Indexed keywords

LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATHETERIZATION; CELL TRANSPLANTATION; COMPARATIVE STUDY; CONTROLLED STUDY; HYPERLIPIDEMIA; ISCHEMIA; LIVER BLOOD FLOW; LIVER CELL; MESENTERIC VEIN; NONHUMAN; PRIORITY JOURNAL; RABBIT; REPERFUSION INJURY; SAFETY; VASCULARIZATION;

ANIMALS; GENE EXPRESSION; HEPATOCYTES; HYPERLIPIDEMIAS; LIVER; LIVER REGENERATION; RABBITS; RECEPTORS, LDL; REPERFUSION INJURY; TRANSPLANTATION, HOMOLOGOUS;

EID: 7244251956     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2004.07.014     Document Type: Article

References (47)

1. K.J. Allen, and H.E. Soriano Liver cell transplantation: the road to clinical application J Lab Clin Med 138 2001 298 312
2. I.J. Fox, J.R. Chowdhury, S.S. Kaufman, T.C. Goertzen, N.R. Chowdhury, and P.I. Warkentin Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation N Engl J Med 338 1998 1422 1426
3. S. Gupta, P. Rajvanshi, K.K. Bhargava, and A. Kerr Hepatocyte transplantation: progress toward liver repopulation Prog Liver Dis 14 1996 199 222
4. M. Muraca, G. Gerunda, D. Neri, M.T. Vilei, A. Granato, and P. Feltracco Hepatocyte transplantation as a treatment for glycogen storage disease type 1a Lancet 359 2002 317 318
5. J.M. DeVree, R. Ottenhoff, P.J. Bosma, A.J. Smith, J. Aten, and R.P. Oude Elferink Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis Gastroenterology 119 2000 1720 1730
6. H. Malhi, A.N. Irani, I. Volenberg, M.L. Schilsky, and S. Gupta Early cell transplantation in LEC rats modeling Wilson's disease eliminates hepatic copper with reversal of liver disease Gastroenterology 122 2002 438 447
7. K. Overturf, M. Al-Dhalimy, R. Tanguay, M. Brantly, C.N. Ou, and M. Finegold Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I Nat Genet 12 1996 266 273
8. E. Laconi, R. Oren, D.K. Mukhopadhyay, E. Hurston, S. Laconi, and P. Pani Long-term, near total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsine Am J Pathol 153 1998 319 329
9. A. Mignon, J.E. Guidotti, C. Mitchell, M. Fabre, A. Wernet, and A. De La Coste Selective repopulation of normal mouse liver by Fas/CD95-resistant hepatocytes Nat Med 4 1998 1185 1188
10. D. Karavias, A.C. Tsamandas, K. Tepetes, N. Kritikos, T. Kourelis, and N. Mirra The effect of ischemia on the regeneration of the cholestatic liver. An experimental study Hepatogastroenterology 49 2002 456 460
11. G.J. Gordon, W.B. Coleman, and J.W. Grisham Bax-mediated apoptosis in the livers of rats after partial hepatectomy in the retrorsine model of hepatocellular injury Hepatology 32 2000 312 320
12. T.M. Pakkanen, M. Laitinen, M. Hippelainen, H. Kallionpaa, P. Lehtolainen, and P. Leppanen Enhanced plasma cholesterol lowering effect of retrovirus-mediated LDL receptor gene transfer to WHHL rabbit liver after improved surgical technique and stimulation of hepatocyte proliferation by combined partial liver resection and thymidine kinase - ganciclovir treatment Gene Ther 6 1999 34 41
13. C.R. Gandhi, N. Murase, V.M. Subbotin, T. Uemura, M. Nalesnik, and A.J. Demetris Portacaval shunt causes apoptosis and liver atrophy in rats despite increases in endogenous levels of major hepatic growth factors J Hepatol 37 2002 340 348
14. H. Ozturk, Y. Yagmur, H. Buyukbayram, A.I. Dokucu, and A. Gurel Effects of the nitric oxide donor molsidomine on the early stages of liver damage in rats with bile duct ligation: a biochemical and immunohistochemical approach Eur Surg Res 34 2002 285 290
15. S. Eguchi, J. Rozga, L.T. Lebow, S.C. Chen, C.C. Wang, and R. Rosenthal Treatment of hypercholesterolemia in the Watanabe rabbit using allogeneic hepatocellular transplantation under a regeneration stimulus Transplantation 62 1996 588 593
16. M. Grossman, S.E. Raper, K. Kozarsky, E.A. Stein, J.F. Engelhardt, and D. Muller Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia Nat Genet 6 1994 335 341
17. K. Tanzawa, M. Shimada, M. Kuroda, Y. Tsujuita, M. Arai, and H. Watanabe WHHL-rabbit. A low density lipoprotein receptor-deficient animal model for familial hypercholesterolemia Fed Eur Biochem Soc Lett 118 1980 81 84
18. A. Schneider, M. Attaran, K.F. Gratz, J.S. Bleck, M. Winkler, and M.P. Manns Intraportal infusion of 99mtechnetium-macro-aggregrated albumin particles and hepatocytes in rabbits: assessment of shunting and portal hemodynamic changes Transplantation 75 2003 296 302
19. M.L. Brown, J.E. Freitas, and H.W. Wahner Useful hepatic parenchymal imaging in hepatobiliary scintigraphy AJR Am J Roentgenol 136 1981 893 895
20. P.O. Seglen Hepatocyte suspensions and cultures as tools in experimental carcinogenesis J Toxicol Environ Health 5 1979 551 560
21. T.O. Daniel, W.J. Schneider, J.L. Goldstein, and M.S. Brown Visualization of lipoprotein receptors by ligand blotting J Biol Chem 258 1983 4606 4611
22. M. Huettinger, J.R. Corbett, W.J. Schneider, J.T. Willerson, M.S. Brown, and J.L. Goldstein Imaging of hepatic low density lipoprotein receptors by radionuclide scintiscanning in vivo Proc Natl Acad Sci USA 81 1984 7599 7603
23. M. Huettinger, W.J. Schneider, Y.K. Ho, J.L. Goldstein, and M.S. Brown Use of monoclonal anti-receptor antibodies to probe the expression of the low density lipoprotein receptor in tissues of normal and Watanabe heritable hyperlipidemic rabbits J Clin Invest 74 1984 1017 1026
24. H. Malhi, G.R. Gorla, A.N. Irani, P. Annamaneni, and S. Gupta Cell transplantation after oxidative hepatic preconditioning with radiation and ischemia reperfusion leads to extensive liver repopulation Proc Natl Acad Sci USA 99 2002 13114 13129
25. J.C. Cutrin, A. Boveris, B. Zingaro, G. Corvetti, and G. Poli In situ determination by surface chemiluminescence of temporal relationships between evolving warm ischemia-reperfusion injury in rat liver and phagocyte activation and recruitment Hepatology 31 2000 622 632
26. H. Malhi, P. Annamaneni, S. Slehria, B. Joseph, K.K. Bhargava, and C.J. Palestro Cyclophosphamide disrupts hepatic sinusoidal endothelium and improves transplanted cell engraftment in rat liver Hepatology 36 2002 112 121
27. T. Cantz, D.M. Zuckerman, M.R. Burda, M. Dandri, B. Göricke, and S. Thalhammer Quantitative gene expression analysis reveals transition of fetal liver progenitor cells to mature hepatocytes after transplantation in uPA/RAG-2 mice Am J Pathol 162 2003 37 45
28. J.S. Sandhu, P.M. Petkov, M.D. Dabeva, and D.A. Shafritz Stem cell properties and repopulation of the rat liver by fetal liver epithelial progenitor cells Am J Pathol 159 2001 1323 1334
29. S. Gupta, P. Rajvanshi, R. Sokhi, S. Slehria, A. Yam, and A. Kerr Entry and integration of transplanted hepatocytes in rat liver plates occur by disruption of hepatic sinusoidal endothelium Hepatology 29 1999 509 519
30. S. Gupta, P. Rajvanshi, A.N. Irani, C.J. Palestro, and K.K. Bhargava Integration and proliferation of transplanted cells in hepatic parenchyma following d-galactosamine-induced acute injury in F344 rats J Pathol 190 2000 203 210
31. S. Laconi, S. Pillai, P.P. Porcu, D.A. Shafritz, P. Pani, and E. Laconi Massive liver replacement by transplanted hepatocytes in the absence of exogenous growth stimuli in rats treated with retrorsine Am J Pathol 158 2001 771 777
32. J.A. Rhim, E.P. Sandgren, R.D. Palmiter, and R.L. Brinster Complete reconstitution of mouse liver with xenogeneic hepatocytes Proc Natl Acad Sci USA 92 1995 4942 4946
33. C. Mitchell, A. Mignon, J.E. Guidotti, S. Besnard, M. Fabre, and N. Duverger Therapeutic liver repopulation in a mouse model of hypercholesterolemia Hum Mol Genet 9 2000 1597 1602
34. J.R. Chowdhury, M. Grossman, S. Gupta, N.R. Chowdhury, J.R. Baker, and J.M. Wilson Long-term improvement of hypercholesterolemia after ex vivo gene therapy in LDLR-deficient rabbits Science 254 1991 1802 1805
35. S. Tashiro Clarification of risk factors for hepatectomy in patients with hepatocellular carcinoma Hepatogastroenterology 49 2002 1625 1631
36. K. Ohashi, F. Park, and M.A. Kay Hepatocyte transplantation: clinical and experimental application J Mol Med 79 2001 617 630
37. S. Gupta, P. Rajvanshi, and C.D. Lee Integration of transplanted hepatocytes into host liver plates demonstrated with dipeptidyl peptidase IV-deficient rats Proc Natl Acad Sci USA 92 1995 5860 5864
38. S. Gupta, P. Rajvanshi, E. Aragona, C.D. Lee, P.R. Yerneni, and R.D. Burk Transplanted hepatocytes proliferate differently after CCl4 treatment and hepatocyte growth factor infusion Am J Physiol 276 1999 G629 G638
39. P. Rajvanshi, A. Kerr, K.K. Bhargava, R.D. Burk, and S. Gupta Studies of liver repopulation using the dipeptidyl peptidase IV-deficient rat and other rodent recipients: cell size and structure relationships regulate capacity for increased transplanted hepatocyte mass in the liver lobule Hepatology 23 1996 482 496
40. J. Rozga, M. Holzman, A.D. Moscioni, H. Fujioka, E. Morsiani, and A.A. Demetriou Repeated intraportal hepatocyte transplantation in analbuminemic rats Cell Transplant 4 1995 237 243
41. M. Andreoletti, N. Loux, C. Vons, T.H. Nguyen, I. Lorand, and D. Mahieu Engraftment of autologous retrovirally transduced hepatocytes after intraportal transplantation into nonhuman primates: implication for ex vivo gene therapy Hum Gene Ther 12 2001 169 179
42. M. Muraca, D. Neri, A. Parenti, P. Feltracco, A. Granato, and M.T. Vilei Intraportal hepatocyte transplantation in the pig: hemodynamic and histopathological study Transplantation 73 2002 890 896
43. P. Rajvanshi, A. Kerr, K.K. Bhargava, R.D. Burk, and S. Gupta Efficacy and safety of repeated hepatocyte transplantation for significant liver repopulation in rodents Gastroenterology 111 1996 1092 1102
44. T. Yamamoto, R.W. Bishop, M.S. Brown, J.L. Goldstein, and D.W. Russell Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbit Science 232 1986 1230 1237
45. M. Shiomi, T. Ito, T. Fujioka, and Y. Tsujita Age-associated decrease in plasma cholesterol and changes in cholesterol metabolism in homozygous Watanabe heritable hyperlipidemic rabbits Metabolism 49 2000 552 556
46. D.O. Taylor, M.L. Barr, B. Radovancevic, D.G. Renlund, R.M. Mentzer Jr, and F.W. Smart A randomized, multicenter comparison of tacrolimus and cyclosporine immunosuppressive regimens in cardiac transplantation: decreased hyperlipidemia and hypertension with tacrolimus J Heart Lung Transplant 18 1999 336 345
47. K. Venkiteswaran, D.S. Sgoutas, N. Santanam, and J.F. Neylan Tacrolimus, cyclosporine and plasma lipoproteins in renal transplant recipients Transpl Int 14 2001 405 410