Evidence for increased levels of positive and negative selection on the X chromosome versus autosomes in humans

Molecular Biology and Evolution

Volumn 31, Issue 9, 2014, Pages 2267-2282

  Veeramah, Krishna R ^a,b   Gutenkunst, Ryan N ^c   Woerner, August E ^a   Watkins, Joseph C ^c   Hammer, Michael F ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

Autosomes; Distribution of fitness effects; Humans; Positive selection; Purifying selection; X chromosome

Indexed keywords

ARTICLE; AUTOSOME; CHIMPANZEE; CONTROLLED STUDY; DISTRIBUTION OF FITNESS EFFECT; EFFECTIVE POPULATION SIZE; EXOME; FEMALE; GENE FREQUENCY; GENE SEQUENCE; GENETIC MODEL; GENETIC VARIABILITY; GORILLA; HUMAN; HUMAN EXPERIMENT; MALE; MOLECULAR EVOLUTION; MUTATION RATE; NATURAL SELECTION; NONHUMAN; NORMAL HUMAN; ORANG UTAN; POSITIVE SELECTION; PURIFYING SELECTION; RHESUS MONKEY; SEX RATIO; WEST AFRICAN; X CHROMOSOME; YORUBA (PEOPLE); AFRICA; AMINO ACID SUBSTITUTION; BIOLOGICAL MODEL; BIOLOGY; BLACK PERSON; CPG ISLAND; DNA SEQUENCE; GENETIC SELECTION; GENETICS; HUMAN CHROMOSOME; PROCEDURES; REPRODUCTIVE FITNESS;

AFRICA, WESTERN; AFRICAN CONTINENTAL ANCESTRY GROUP; AMINO ACID SUBSTITUTION; CHROMOSOMES, HUMAN; CHROMOSOMES, HUMAN, X; COMPUTATIONAL BIOLOGY; CPG ISLANDS; EVOLUTION, MOLECULAR; EXOME; FEMALE; GENE FREQUENCY; GENETIC FITNESS; HUMANS; MALE; MODELS, GENETIC; SELECTION, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 84906770344     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msu166     Document Type: Article

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