Hypomethylating agent 5-Aza-2′-deoxycytidine (DAC) ameliorates multiple sclerosis in mouse models

Journal of Cellular Physiology

Volumn 229, Issue 12, 2014, Pages 1918-1925

  Mangano, Katia ^a   Fagone, Paolo ^a   Bendtzen, Klaus ^b   Meroni, Pier Luigi ^c   Quattrocchi, Cinzia ^a   Mammana, Santa ^a   Di Rosa, Michelino ^a   Malaguarnera, Lucia ^a   Coco, Marinella ^a   Magro, Gaetano ^d   Di Marco, Roberto ^e   Nicoletti, Ferdinando ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b Rigshospitalet   (Denmark)

^c UNIVERSITY OF MILAN   (Italy)

^d UNIVERSITY OF CATANIA   (Italy)

^e UNIVERSITY OF MOLISE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AUTACOID; INTERLEUKIN 6; MESSENGER RNA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CPG ISLAND; CYTOKINE RELEASE; DISEASE COURSE; DISEASE SEVERITY; DNA METHYLATION; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; LYMPHOCYTE COUNT; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SPINAL CORD; TH1 CELL; TH17 CELL; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; AZACITIDINE; CYTOKINES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; MICE; MULTIPLE SCLEROSIS; T-LYMPHOCYTES, REGULATORY;

EID: 84906690218     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24641     Document Type: Article

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