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Volumn 5, Issue 11, 2006, Pages 891-892

Decitabine

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; CHELATING AGENT; CYTARABINE; DEFERASIROX; DNA; DNA METHYLTRANSFERASE INHIBITOR; HISTONE DEACETYLASE INHIBITOR; LENALIDOMIDE; NUCLEOSIDE ANALOG; PROTEIN P15;

EID: 33750524236     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd2180     Document Type: Article
Times cited : (99)

References (19)
  • 2
    • 31344450167 scopus 로고    scopus 로고
    • Methylation inhibitor therapy in the treatment of myelodysplastic syndrome
    • Silverman, L. R. & Mufti, G. J. Methylation inhibitor therapy in the treatment of myelodysplastic syndrome. Nature Clin. Pract. Oncol. 2, S12-S23 (2005).
    • (2005) Nature Clin. Pract. Oncol. , vol.2
    • Silverman, L.R.1    Mufti, G.J.2
  • 5
    • 0018860957 scopus 로고
    • Cellular differentiation, cytidine analogues and DNA methylation
    • Jones, P. A. & Taylor, S. M. Cellular differentiation, cytidine analogues and DNA methylation. Cell 20, 85-93 (1980).
    • (1980) Cell , vol.20 , pp. 85-93
    • Jones, P.A.1    Taylor, S.M.2
  • 6
    • 0004959517 scopus 로고
    • Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta globin gene complex
    • Charache, S. et al. Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta globin gene complex. Proc. Natl Acad. Sci. USA 80, 4842-4846 (1983).
    • (1983) Proc. Natl Acad. Sci. USA , vol.80 , pp. 4842-4846
    • Charache, S.1
  • 7
    • 0037108309 scopus 로고    scopus 로고
    • Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-aza-2′-deoxycytidine (decitabine) treatment
    • Daskalakis, M. et al. Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-aza-2′-deoxycytidine (decitabine) treatment. Blood 100, 2957-2964 (2002).
    • (2002) Blood , vol.100 , pp. 2957-2964
    • Daskalakis, M.1
  • 8
    • 33750534233 scopus 로고    scopus 로고
    • FDA labelling information [online]
    • FDA labelling information [online], (2006).
    • (2006)
  • 9
    • 33646071894 scopus 로고    scopus 로고
    • Decitabine improves patient outcomes in myelodysplastic syndromes: Results of a Phase III randomized study
    • Kantarjian, H. et al. Decitabine improves patient outcomes in myelodysplastic syndromes: Results of a Phase III randomized study. Cancer 106, 1794-1803 (2006).
    • (2006) Cancer , vol.106 , pp. 1794-1803
    • Kantarjian, H.1
  • 10
    • 17444452612 scopus 로고    scopus 로고
    • Low-dose 5-aza-2′-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: A multicenter phase II study in elderly patients
    • Wijermans, P. et al. Low-dose 5-aza-2′-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: A multicenter phase II study in elderly patients. J. Clin. Oncol. 18, 956-962 (2000).
    • (2000) J. Clin. Oncol. , vol.18 , pp. 956-962
    • Wijermans, P.1
  • 11
    • 13444256401 scopus 로고    scopus 로고
    • Efficacy of lenalidomide in myelodysplastic syndromes
    • List, A. et al. Efficacy of lenalidomide in myelodysplastic syndromes. N. Engl. J. Med. 352, 549-557 (2005).
    • (2005) N. Engl. J. Med. , vol.352 , pp. 549-557
    • List, A.1
  • 12
    • 0037093195 scopus 로고    scopus 로고
    • Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: A study of the cancer and leukemia group B
    • Silverman, L. R. et al. Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: A study of the cancer and leukemia group B. J. Clin. Oncol. 20, 2429-2440 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , pp. 2429-2440
    • Silverman, L.R.1
  • 13
    • 0037092962 scopus 로고    scopus 로고
    • Impact of azacytidine on the quality of life of patients with myelodysplastic syndrome treated in a randomized phase III trial: A Cancer and Leukemia Group B study
    • Kornblith, A. B. et al. Impact of azacytidine on the quality of life of patients with myelodysplastic syndrome treated in a randomized phase III trial: A Cancer and Leukemia Group B study. J. Clin. Oncol. 20, 2441-2452 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , pp. 2441-2452
    • Kornblith, A.B.1
  • 14
    • 33745714230 scopus 로고    scopus 로고
    • Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms
    • Gore, S. D. et al. Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms. Cancer Res. 66, 6361-6369 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 6361-6369
    • Gore, S.D.1
  • 15
    • 45749096371 scopus 로고    scopus 로고
    • Results of a randomized study of three schedules of low-dose decitabine in higher risk myelodysplastic syndrome and chronic myelomonocytic leukemia
    • 1 Aug (doi: blood-2006-05-021162v1)
    • Kantarjian, H. et al. Results of a randomized study of three schedules of low-dose decitabine in higher risk myelodysplastic syndrome and chronic myelomonocytic leukemia. Blood 1 Aug 2006 (doi: blood-2006-05-021162v1).
    • (2006) Blood
    • Kantarjian, H.1
  • 16
    • 85117737422 scopus 로고    scopus 로고
    • Phase I/II study of the combination of 5-aza-2′-deoxycytidine with valproic acid in patients with leukemia
    • 1 Aug (doi: blood-2006-03-009142v1)
    • Garcia-Manero, G. et al. Phase I/II study of the combination of 5-aza-2′-deoxycytidine with valproic acid in patients with leukemia. Blood 1 Aug 2006 (doi: Blood-2006-03-009142v1).
    • (2006) Blood
    • Garcia-Manero, G.1
  • 17
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
    • Cameron, E. E. et al. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nature Genet. 21, 103-107 (1999).
    • (1999) Nature Genet. , vol.21 , pp. 103-107
    • Cameron, E.E.1
  • 18
    • 33750509694 scopus 로고    scopus 로고
    • (Aplastic Anemia & MDS International Foundation, Annapolis, Maryland)
    • Myelodysplastic Syndromes: Basic Explanations 1-19 (Aplastic Anemia & MDS International Foundation, Annapolis, Maryland, 2005).
    • (2005) Myelodysplastic Syndromes: Basic Explanations , pp. 1-19
  • 19
    • 33750499152 scopus 로고    scopus 로고
    • IMS Health, IMS MIDAS MAT (June)
    • IMS Health, IMS MIDAS MAT (June 2006).
    • (2006)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.