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Volumn 229, Issue 12, 2014, Pages 1887-1895

Isoforms of Receptors of Fibroblast Growth Factors

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; FIBROBLAST GROWTH FACTOR RECEPTOR; ISOPROTEIN; LIGAND; TYROSINE KINASE RECEPTOR;

EID: 84906673934     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24649     Document Type: Review
Times cited : (68)

References (130)
  • 1
    • 84857433085 scopus 로고    scopus 로고
    • Mechanisms of FGFR-mediated carcinogenesis
    • Ahmad I, Iwata T, Leung HY. 2012. Mechanisms of FGFR-mediated carcinogenesis. Biochim Biophys Acta 1823:850-860.
    • (2012) Biochim Biophys Acta , vol.1823 , pp. 850-860
    • Ahmad, I.1    Iwata, T.2    Leung, H.Y.3
  • 2
    • 0027255139 scopus 로고
    • A novel form of FGF receptor-3 using alternative exon in the immunoglobulin domain III
    • Avivi A, Yayon A, Givol D. 1993. A novel form of FGF receptor-3 using alternative exon in the immunoglobulin domain III. FEBS Lett 330:249-252.
    • (1993) FEBS Lett , vol.330 , pp. 249-252
    • Avivi, A.1    Yayon, A.2    Givol, D.3
  • 5
    • 41549162752 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states in development and disease
    • Baum B, Settleman J, Quinlan MP. 2008. Transitions between epithelial and mesenchymal states in development and disease. Semin Cell Dev Biol 19:294-308.
    • (2008) Semin Cell Dev Biol , vol.19 , pp. 294-308
    • Baum, B.1    Settleman, J.2    Quinlan, M.P.3
  • 6
    • 0001194208 scopus 로고
    • Genetic control of biochemical reactions in neurospora
    • Beadle GW, Tatum EL. 1941. Genetic control of biochemical reactions in neurospora. Proc Natl Acad Sci USA 27:499-506.
    • (1941) Proc Natl Acad Sci USA , vol.27 , pp. 499-506
    • Beadle, G.W.1    Tatum, E.L.2
  • 7
    • 61649100307 scopus 로고    scopus 로고
    • The FGF family: Biology, pathophysiology and therapy
    • Beenken A, Mohammadi M. 2009. The FGF family: Biology, pathophysiology and therapy. Nat Rev Drug Discov 8:235-253.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 235-253
    • Beenken, A.1    Mohammadi, M.2
  • 8
    • 0025787197 scopus 로고
    • Expression of two different forms of fibroblast growth factor receptor 1 in different mouse tissues and cell lines
    • Bernard O, Li M, Reid HH. 1991. Expression of two different forms of fibroblast growth factor receptor 1 in different mouse tissues and cell lines. Proc Natl Acad Sci USA 88:7625-7629.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7625-7629
    • Bernard, O.1    Li, M.2    Reid, H.H.3
  • 9
    • 0037040282 scopus 로고    scopus 로고
    • Association of the signaling adaptor FRS2 with fibroblast growth factor receptor 1 (Fgfr1) is mediated by alternative splicing of the juxtamembrane domain
    • Burgar HR, Burns HD, Elsden JL, Lalioti MD, Heath JK. 2002. Association of the signaling adaptor FRS2 with fibroblast growth factor receptor 1 (Fgfr1) is mediated by alternative splicing of the juxtamembrane domain. J Biol Chem 277:4018-4023.
    • (2002) J Biol Chem , vol.277 , pp. 4018-4023
    • Burgar, H.R.1    Burns, H.D.2    Elsden, J.L.3    Lalioti, M.D.4    Heath, J.K.5
  • 10
    • 13444263240 scopus 로고    scopus 로고
    • Fibroblast growth factor signaling during early vertebrate development
    • Böttcher RT, Niehrs C. 2005. Fibroblast growth factor signaling during early vertebrate development. Endocr Rev 26:63-77.
    • (2005) Endocr Rev , vol.26 , pp. 63-77
    • Böttcher, R.T.1    Niehrs, C.2
  • 11
    • 40949090037 scopus 로고    scopus 로고
    • Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis
    • Cha JY, Lambert QT, Reuther GW, Der CJ. 2008. Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis. Mol Cancer Res 6:435-445.
    • (2008) Mol Cancer Res , vol.6 , pp. 435-445
    • Cha, J.Y.1    Lambert, Q.T.2    Reuther, G.W.3    Der, C.J.4
  • 12
    • 65249140043 scopus 로고    scopus 로고
    • Aberrant receptor internalization and enhanced FRS2-dependent signaling contribute to the transforming activity of the fibroblast growth factor receptor 2 IIIb C3 isoform
    • Cha JY, Maddileti S, Mitin N, Harden TK, Der CJ. 2009. Aberrant receptor internalization and enhanced FRS2-dependent signaling contribute to the transforming activity of the fibroblast growth factor receptor 2 IIIb C3 isoform. J Biol Chem 284:6227-6240.
    • (2009) J Biol Chem , vol.284 , pp. 6227-6240
    • Cha, J.Y.1    Maddileti, S.2    Mitin, N.3    Harden, T.K.4    Der, C.J.5
  • 13
    • 33845809125 scopus 로고    scopus 로고
    • Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: Role of fibroblast growth factor receptor-2
    • Chaffer CL, Brennan JP, Slavin JL, Blick T, Thompson EW, Williams ED. 2006. Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: Role of fibroblast growth factor receptor-2. Cancer Res 66:11271-11278.
    • (2006) Cancer Res , vol.66 , pp. 11271-11278
    • Chaffer, C.L.1    Brennan, J.P.2    Slavin, J.L.3    Blick, T.4    Thompson, E.W.5    Williams, E.D.6
  • 15
    • 42449129287 scopus 로고    scopus 로고
    • Searching for splicing motifs
    • Chasin LA. 2007. Searching for splicing motifs. Adv Exp Med Biol 623:85-106.
    • (2007) Adv Exp Med Biol , vol.623 , pp. 85-106
    • Chasin, L.A.1
  • 16
    • 0033520935 scopus 로고    scopus 로고
    • Mapping ligand binding domains in chimeric fibroblast growth factor receptor molecules. Multiple regions determine ligand binding specificity
    • Chellaiah A, Yuan W, Chellaiah M, Ornitz DM. 1999. Mapping ligand binding domains in chimeric fibroblast growth factor receptor molecules. Multiple regions determine ligand binding specificity. J Biol Chem 274:34785-34794.
    • (1999) J Biol Chem , vol.274 , pp. 34785-34794
    • Chellaiah, A.1    Yuan, W.2    Chellaiah, M.3    Ornitz, D.M.4
  • 17
    • 0028117373 scopus 로고
    • High-affinity binding sites for related fibroblast growth factor ligands reside within different receptor immunoglobulin-like domains
    • Cheon HG, LaRochelle WJ, Bottaro DP, Burgess WH, Aaronson SA. 1994. High-affinity binding sites for related fibroblast growth factor ligands reside within different receptor immunoglobulin-like domains. Proc Natl Acad Sci USA 91:989-993.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 989-993
    • Cheon, H.G.1    LaRochelle, W.J.2    Bottaro, D.P.3    Burgess, W.H.4    Aaronson, S.A.5
  • 18
    • 80052944612 scopus 로고    scopus 로고
    • Neural cell adhesion molecule differentially interacts with isoforms of the fibroblast growth factor receptor
    • Christensen C, Berezin V, Bock E. 2011. Neural cell adhesion molecule differentially interacts with isoforms of the fibroblast growth factor receptor. Neuroreport 22:727-732.
    • (2011) Neuroreport , vol.22 , pp. 727-732
    • Christensen, C.1    Berezin, V.2    Bock, E.3
  • 20
    • 78149263789 scopus 로고    scopus 로고
    • FGF signalling: Diverse roles during early vertebrate embryogenesis
    • Dorey K, Amaya E. 2010. FGF signalling: Diverse roles during early vertebrate embryogenesis. Development 137:3731-3742.
    • (2010) Development , vol.137 , pp. 3731-3742
    • Dorey, K.1    Amaya, E.2
  • 21
    • 0031947059 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor expression reflects cellular differentiation in human oral squamous carcinoma cell lines
    • Drugan CS, Paterson IC, Prime SS. 1998. Fibroblast growth factor receptor expression reflects cellular differentiation in human oral squamous carcinoma cell lines. Carcinogenesis 19:1153-1156.
    • (1998) Carcinogenesis , vol.19 , pp. 1153-1156
    • Drugan, C.S.1    Paterson, I.C.2    Prime, S.S.3
  • 22
    • 0026674594 scopus 로고
    • A naturally occurring secreted form of fibroblast growth factor (FGF) receptor 1 binds basic FGF in preference over acidic FGF
    • Duan DS, Werner S, Williams LT. 1992. A naturally occurring secreted form of fibroblast growth factor (FGF) receptor 1 binds basic FGF in preference over acidic FGF. J Biol Chem 267:16076-16080.
    • (1992) J Biol Chem , vol.267 , pp. 16076-16080
    • Duan, D.S.1    Werner, S.2    Williams, L.T.3
  • 24
    • 0025838084 scopus 로고
    • Alternative splicing generates at least five different isoforms of the human basic-FGF receptor
    • Eisemann A, Ahn J, Graziani G, Tronick S, Ron D. 1991. Alternative splicing generates at least five different isoforms of the human basic-FGF receptor. Oncogene 6:1195-1202.
    • (1991) Oncogene , vol.6 , pp. 1195-1202
    • Eisemann, A.1    Ahn, J.2    Graziani, G.3    Tronick, S.4    Ron, D.5
  • 26
    • 0037443035 scopus 로고    scopus 로고
    • Pre-mRNA splicing and human disease
    • Faustino NA, Cooper TA. 2003. Pre-mRNA splicing and human disease. Genes Dev 17:419-437.
    • (2003) Genes Dev , vol.17 , pp. 419-437
    • Faustino, N.A.1    Cooper, T.A.2
  • 27
    • 0018263844 scopus 로고
    • Why genes in pieces?
    • Gilbert W. 1978. Why genes in pieces? Nature 271:501.
    • (1978) Nature , vol.271 , pp. 501
    • Gilbert, W.1
  • 28
    • 0032954333 scopus 로고    scopus 로고
    • Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer
    • Giri D, Ropiquet F, Ittmann M. 1999. Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer. Clin Cancer Res 5:1063-1071.
    • (1999) Clin Cancer Res , vol.5 , pp. 1063-1071
    • Giri, D.1    Ropiquet, F.2    Ittmann, M.3
  • 29
    • 18144413583 scopus 로고    scopus 로고
    • Fibroblast growth factor signaling in tumorigenesis
    • Grose R, Dickson C. 2005. Fibroblast growth factor signaling in tumorigenesis. Cytokine Growth Factor Rev 16:179-186.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 179-186
    • Grose, R.1    Dickson, C.2
  • 30
    • 0036362757 scopus 로고    scopus 로고
    • The structure and function of vertebrate fibroblast growth factor receptor 1
    • Groth C, Lardelli M. 2002. The structure and function of vertebrate fibroblast growth factor receptor 1. Int J Dev Biol 46:393-400.
    • (2002) Int J Dev Biol , vol.46 , pp. 393-400
    • Groth, C.1    Lardelli, M.2
  • 31
    • 80051904826 scopus 로고    scopus 로고
    • From cradle to grave: The multiple roles of fibroblast growth factors in neural development
    • Guillemot F, Zimmer C. 2011. From cradle to grave: The multiple roles of fibroblast growth factors in neural development. Neuron 71(4):574-588.
    • (2011) Neuron , vol.71 , Issue.4 , pp. 574-588
    • Guillemot, F.1    Zimmer, C.2
  • 32
    • 0035793430 scopus 로고    scopus 로고
    • Structural characterization of the circulating soluble FGF receptors reveals multiple isoforms generated by secretion and ectodomain shedding
    • Hanneken A. 2001. Structural characterization of the circulating soluble FGF receptors reveals multiple isoforms generated by secretion and ectodomain shedding. FEBS Lett 489:176-181.
    • (2001) FEBS Lett , vol.489 , pp. 176-181
    • Hanneken, A.1
  • 33
    • 0033523757 scopus 로고    scopus 로고
    • Localization of putative stem cells in dental epithelium and their association with Notch and FGF signaling
    • Harada H, Kettunen P, Jung HS, Mustonen T, Wang YA, Thesleff I. 1999. Localization of putative stem cells in dental epithelium and their association with Notch and FGF signaling. J Cell Biol 147:105-120.
    • (1999) J Cell Biol , vol.147 , pp. 105-120
    • Harada, H.1    Kettunen, P.2    Jung, H.S.3    Mustonen, T.4    Wang, Y.A.5    Thesleff, I.6
  • 36
    • 0026697907 scopus 로고
    • Cloning, expression and tissue distribution of the gene encoding rat fibroblast growth factor receptor subtype 4
    • Horlick RA, Stack SL, Cooke GM. 1992. Cloning, expression and tissue distribution of the gene encoding rat fibroblast growth factor receptor subtype 4. Gene 120:291-295.
    • (1992) Gene , vol.120 , pp. 291-295
    • Horlick, R.A.1    Stack, S.L.2    Cooke, G.M.3
  • 37
    • 0026738953 scopus 로고
    • Substitution of putative half-cystine residues in heparin-binding fibroblast growth factor receptors. Loss of binding activity in both two and three loop isoforms
    • Hou J, Kan M, Wang F, Xu JM, Nakahara M, McBride G, McKeehan K, McKeehan WL. 1992. Substitution of putative half-cystine residues in heparin-binding fibroblast growth factor receptors. Loss of binding activity in both two and three loop isoforms. J Biol Chem 267:17804-17808.
    • (1992) J Biol Chem , vol.267 , pp. 17804-17808
    • Hou, J.1    Kan, M.2    Wang, F.3    Xu, J.M.4    Nakahara, M.5    McBride, G.6    McKeehan, K.7    McKeehan, W.L.8
  • 38
    • 37549039473 scopus 로고    scopus 로고
    • Heterogeneous ribonucleoprotein m is a splicing regulatory protein that can enhance or silence splicing of alternatively spliced exons
    • Hovhannisyan RH, Carstens RP. 2007. Heterogeneous ribonucleoprotein m is a splicing regulatory protein that can enhance or silence splicing of alternatively spliced exons. J Biol Chem 282:36265-36274.
    • (2007) J Biol Chem , vol.282 , pp. 36265-36274
    • Hovhannisyan, R.H.1    Carstens, R.P.2
  • 39
    • 1942470528 scopus 로고    scopus 로고
    • Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assemblyâ€
    • Ibrahimi OA, Zhang F, Lang Hrstka SC, Mohammadi M, Linhardt RJ. 2004. Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assemblyâ€. Biochemistry 43:4724-4730.
    • (2004) Biochemistry , vol.43 , pp. 4724-4730
    • Ibrahimi, O.A.1    Zhang, F.2    Lang Hrstka, S.C.3    Mohammadi, M.4    Linhardt, R.J.5
  • 40
    • 0028305121 scopus 로고
    • Preferential alternative splicing in cancer generates a K-sam messenger RNA with higher transforming activity
    • Itoh K, Hattori Y, Sakamoto H. 1994. Preferential alternative splicing in cancer generates a K-sam messenger RNA with higher transforming activity. Cancer Res 54:3237-3241.
    • (1994) Cancer Res , vol.54 , pp. 3237-3241
    • Itoh, K.1    Hattori, Y.2    Sakamoto, H.3
  • 41
    • 0037430451 scopus 로고    scopus 로고
    • Loss of ligand-binding specificity of fibroblast growth factor receptor 2 by RNA splicing in human chondrosarcoma cells
    • Jang JH, Chung CP. 2003. Loss of ligand-binding specificity of fibroblast growth factor receptor 2 by RNA splicing in human chondrosarcoma cells. Cancer Lett 191:215-222.
    • (2003) Cancer Lett , vol.191 , pp. 215-222
    • Jang, J.H.1    Chung, C.P.2
  • 42
    • 0033900046 scopus 로고    scopus 로고
    • Novel transcripts of fibroblast growth factor receptor 3 reveal aberrant splicing and activation of cryptic splice sequences in colorectal cancer
    • Jang JH, Shin KH, Park YJ, Lee RJ, McKeehan WL, Park JG. 2000. Novel transcripts of fibroblast growth factor receptor 3 reveal aberrant splicing and activation of cryptic splice sequences in colorectal cancer. Cancer Res 60:4049-4052.
    • (2000) Cancer Res , vol.60 , pp. 4049-4052
    • Jang, J.H.1    Shin, K.H.2    Park, Y.J.3    Lee, R.J.4    McKeehan, W.L.5    Park, J.G.6
  • 43
    • 0037442833 scopus 로고    scopus 로고
    • Alternatively spliced FGFR-1 isoform signaling differentially modulates endothelial cell responses to peroxynitrite
    • Jiao J, Greendorfer JS, Zhang P, Zinn KR, Diglio CA, Thompson JA. 2003. Alternatively spliced FGFR-1 isoform signaling differentially modulates endothelial cell responses to peroxynitrite. Arch Biochem Biophys 410:187-200.
    • (2003) Arch Biochem Biophys , vol.410 , pp. 187-200
    • Jiao, J.1    Greendorfer, J.S.2    Zhang, P.3    Zinn, K.R.4    Diglio, C.A.5    Thompson, J.A.6
  • 44
    • 10844260793 scopus 로고    scopus 로고
    • Enhancer-dependent splicing of FGFR1 alpha-exon is repressed by RNA interference-mediated down-regulation of SRp55
    • Jin W, Cote GJ. 2004. Enhancer-dependent splicing of FGFR1 alpha-exon is repressed by RNA interference-mediated down-regulation of SRp55. Cancer Res 64:8901-8905.
    • (2004) Cancer Res , vol.64 , pp. 8901-8905
    • Jin, W.1    Cote, G.J.2
  • 45
    • 0032568825 scopus 로고    scopus 로고
    • Exon sequence is required for regulated RNA splicing of the human fibroblast growth factor receptor-1 alpha-exon
    • Jin W, Huang ES, Bi W, Cote GJ. 1998. Exon sequence is required for regulated RNA splicing of the human fibroblast growth factor receptor-1 alpha-exon. J Biol Chem 273:16170-16176.
    • (1998) J Biol Chem , vol.273 , pp. 16170-16176
    • Jin, W.1    Huang, E.S.2    Bi, W.3    Cote, G.J.4
  • 46
    • 0033600792 scopus 로고    scopus 로고
    • Redundant intronic repressors function to inhibit fibroblast growth factor receptor-1 alpha-exon recognition in glioblastoma cells
    • Jin W, Huang ES, Bi W, Cote GJ. 1999. Redundant intronic repressors function to inhibit fibroblast growth factor receptor-1 alpha-exon recognition in glioblastoma cells. J Biol Chem 274:28035-28041.
    • (1999) J Biol Chem , vol.274 , pp. 28035-28041
    • Jin, W.1    Huang, E.S.2    Bi, W.3    Cote, G.J.4
  • 47
    • 0027344852 scopus 로고
    • Structural and functional diversity in the FGF receptor multigene family
    • Johnson D, Williams L. 1993. Structural and functional diversity in the FGF receptor multigene family. Adv Cancer Res 60:1-4.
    • (1993) Adv Cancer Res , vol.60 , pp. 1-4
    • Johnson, D.1    Williams, L.2
  • 48
    • 0025122589 scopus 로고
    • Diverse forms of a receptor for acidic and basic fibroblast growth factors
    • Johnson DE, Lee PL, Lu J, Williams LT. 1990. Diverse forms of a receptor for acidic and basic fibroblast growth factors. Mol Cell Biol 10:4728-4736.
    • (1990) Mol Cell Biol , vol.10 , pp. 4728-4736
    • Johnson, D.E.1    Lee, P.L.2    Lu, J.3    Williams, L.T.4
  • 49
    • 0025912340 scopus 로고
    • The human fibroblast growth factor receptor genes: A common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain
    • Johnson DE, Lu J, Chen H, Werner S, Williams LT. 1991. The human fibroblast growth factor receptor genes: A common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain. Mol Cell Biol 11:4627-4634.
    • (1991) Mol Cell Biol , vol.11 , pp. 4627-4634
    • Johnson, D.E.1    Lu, J.2    Chen, H.3    Werner, S.4    Williams, L.T.5
  • 50
    • 0029559922 scopus 로고
    • Fibroblast growth factor receptors (FGFRs) localize in different cellular compartments. A splice variant of FGFR-3 localizes to the nucleus
    • Johnston CL, Cox HC, Gomm JJ, Coombes RC. 1995. Fibroblast growth factor receptors (FGFRs) localize in different cellular compartments. A splice variant of FGFR-3 localizes to the nucleus. J Biol Chem 270:30643-30650.
    • (1995) J Biol Chem , vol.270 , pp. 30643-30650
    • Johnston, C.L.1    Cox, H.C.2    Gomm, J.J.3    Coombes, R.C.4
  • 52
    • 0027192075 scopus 로고
    • An essential heparin-binding domain in the fibroblast growth factor receptor kinase
    • Kan M, Wang F, Xu J, Crabb JW, Hou J, McKeehan WL. 1993. An essential heparin-binding domain in the fibroblast growth factor receptor kinase. Science 259:1918-1921.
    • (1993) Science , vol.259 , pp. 1918-1921
    • Kan, M.1    Wang, F.2    Xu, J.3    Crabb, J.W.4    Hou, J.5    McKeehan, W.L.6
  • 53
    • 0034119439 scopus 로고    scopus 로고
    • FGF receptor mutations: Dimerization syndromes, cell growth suppression, and animal models
    • Kannan K, Givol D. 2000. FGF receptor mutations: Dimerization syndromes, cell growth suppression, and animal models. IUBMB Life 49:197-205.
    • (2000) IUBMB Life , vol.49 , pp. 197-205
    • Kannan, K.1    Givol, D.2
  • 54
    • 0031859797 scopus 로고    scopus 로고
    • Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9
    • Kettunen P, Karavanova I, Thesleff I. 1998. Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9. Dev Genet 22:374-385.
    • (1998) Dev Genet , vol.22 , pp. 374-385
    • Kettunen, P.1    Karavanova, I.2    Thesleff, I.3
  • 55
    • 0033766365 scopus 로고    scopus 로고
    • Associations of FGF-3 and FGF-10 with signaling networks regulating tooth morphogenesis
    • Kettunen P, Laurikkala J, Itäranta P, Vainio S, Itoh N, Thesleff I. 2000. Associations of FGF-3 and FGF-10 with signaling networks regulating tooth morphogenesis. Dev Dyn 219:322-332.
    • (2000) Dev Dyn , vol.219 , pp. 322-332
    • Kettunen, P.1    Laurikkala, J.2    Itäranta, P.3    Vainio, S.4    Itoh, N.5    Thesleff, I.6
  • 56
    • 0027365931 scopus 로고
    • Aberrant expression of type I fibroblast growth factor receptor in human pancreatic adenocarcinomas
    • Kobrin MS, Yamanaka Y, Friess H, Lopez ME, Korc M. 1993. Aberrant expression of type I fibroblast growth factor receptor in human pancreatic adenocarcinomas. Cancer Res 53:4741-4744.
    • (1993) Cancer Res , vol.53 , pp. 4741-4744
    • Kobrin, M.S.1    Yamanaka, Y.2    Friess, H.3    Lopez, M.E.4    Korc, M.5
  • 57
    • 0032007440 scopus 로고    scopus 로고
    • Genomic structure and complete sequence of the human FGFR4 gene
    • Kostrzewa M, Müller U. 1998. Genomic structure and complete sequence of the human FGFR4 gene. Mamm Genome 9:131-135.
    • (1998) Mamm Genome , vol.9 , pp. 131-135
    • Kostrzewa, M.1    Müller, U.2
  • 58
    • 0035253320 scopus 로고    scopus 로고
    • Alternative splicing of fibroblast growth factor receptors in human prostate cancer
    • Kwabi-Addo B, Ropiquet F, Giri D, Ittmann M. 2001. Alternative splicing of fibroblast growth factor receptors in human prostate cancer. Prostate 46:163-172.
    • (2001) Prostate , vol.46 , pp. 163-172
    • Kwabi-Addo, B.1    Ropiquet, F.2    Giri, D.3    Ittmann, M.4
  • 59
    • 59649103708 scopus 로고    scopus 로고
    • FGFR2 in the dental epithelium is essential for development and maintenance of the maxillary cervical loop, a stem cell niche in mouse incisors
    • Lin Y, Cheng YS, Qin C, Lin C, D'Souza R, Wang F. 2009. FGFR2 in the dental epithelium is essential for development and maintenance of the maxillary cervical loop, a stem cell niche in mouse incisors. Dev Dyn 238:324-330.
    • (2009) Dev Dyn , vol.238 , pp. 324-330
    • Lin, Y.1    Cheng, Y.S.2    Qin, C.3    Lin, C.4    D'Souza, R.5    Wang, F.6
  • 60
    • 0032435862 scopus 로고    scopus 로고
    • Alternative splicing of pre-mRNA: Developmental consequences and mechanisms of regulation
    • Lopez AJ. 1998. Alternative splicing of pre-mRNA: Developmental consequences and mechanisms of regulation. Annu Rev Genet 32:279-305.
    • (1998) Annu Rev Genet , vol.32 , pp. 279-305
    • Lopez, A.J.1
  • 61
    • 0026696081 scopus 로고
    • Expression of basic fibroblast growth factor, FGFR1 and FGFR2 in normal and malignant human breast and comparison with other normal tissues
    • Luqmani YA, Graham M, Coombes RC. 1992. Expression of basic fibroblast growth factor, FGFR1 and FGFR2 in normal and malignant human breast and comparison with other normal tissues. Br J Cancer 66:273-280.
    • (1992) Br J Cancer , vol.66 , pp. 273-280
    • Luqmani, Y.A.1    Graham, M.2    Coombes, R.C.3
  • 62
    • 19444368979 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in mammals
    • Maquat LE. 2005. Nonsense-mediated mRNA decay in mammals J Cell Sci 118:1773-1776.
    • (2005) J Cell Sci , vol.118 , pp. 1773-1776
    • Maquat, L.E.1
  • 64
    • 84858960891 scopus 로고    scopus 로고
    • FGF/FGFR signaling in bone formation: progress and perspectives
    • Marie PJ, Miraoui H, Sévère N. 2012. FGF/FGFR signaling in bone formation: progress and perspectives. Growth Factors 30:117-123.
    • (2012) Growth Factors , vol.30 , pp. 117-123
    • Marie, P.J.1    Miraoui, H.2    Sévère, N.3
  • 65
    • 18344364099 scopus 로고    scopus 로고
    • Understanding alternative splicing: Towards a cellular code
    • Matlin AJ, Clark F, Smith CW. 2005. Understanding alternative splicing: Towards a cellular code. Nat Rev Mol Cell Biol 6:386-398.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 386-398
    • Matlin, A.J.1    Clark, F.2    Smith, C.W.3
  • 66
    • 84866095723 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 IIIc as a therapeutic target for colorectal cancer cells
    • Matsuda Y, Hagio M, Seya T, Ishiwata T. 2012. Fibroblast growth factor receptor 2 IIIc as a therapeutic target for colorectal cancer cells. Mol Cancer Ther 11:2010-2020.
    • (2012) Mol Cancer Ther , vol.11 , pp. 2010-2020
    • Matsuda, Y.1    Hagio, M.2    Seya, T.3    Ishiwata, T.4
  • 67
    • 50249176008 scopus 로고    scopus 로고
    • HnRNP H and hnRNP F complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIc
    • Mauger DM, Lin C, Garcia-Blanco MA. 2008. HnRNP H and hnRNP F complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIc. Mol Cell Biol 28:5403-5419.
    • (2008) Mol Cell Biol , vol.28 , pp. 5403-5419
    • Mauger, D.M.1    Lin, C.2    Garcia-Blanco, M.A.3
  • 68
    • 0031600117 scopus 로고    scopus 로고
    • The heparan sulfate-fibroblast growth factor family: Diversity of structure and function
    • McKeehan W, Wang F, Kan M. 1998. The heparan sulfate-fibroblast growth factor family: Diversity of structure and function. Prog Nucleic Acid Res Mol Biol 59:135-176.
    • (1998) Prog Nucleic Acid Res Mol Biol , vol.59 , pp. 135-176
    • McKeehan, W.1    Wang, F.2    Kan, M.3
  • 69
    • 0027940213 scopus 로고
    • Heparan sulfate fibroblast growth factor receptor complex: Structure-function relationships
    • McKeehan WL, Kan M. 1994. Heparan sulfate fibroblast growth factor receptor complex: Structure-function relationships. Mol Reprod Dev 39:62-81.
    • (1994) Mol Reprod Dev , vol.39 , pp. 62-81
    • McKeehan, W.L.1    Kan, M.2
  • 70
  • 71
    • 0036337915 scopus 로고    scopus 로고
    • A genomic view of alternative splicing
    • Modrek B, Lee C. 2002. A genomic view of alternative splicing. Nat Genet 30:13-19.
    • (2002) Nat Genet , vol.30 , pp. 13-19
    • Modrek, B.1    Lee, C.2
  • 72
  • 73
    • 0029132035 scopus 로고
    • Fibroblast-growth-factor receptor mutations in human skeletal disorders
    • Muenke M, Schell U. 1995. Fibroblast-growth-factor receptor mutations in human skeletal disorders. Trends Genet 11:308-313.
    • (1995) Trends Genet , vol.11 , pp. 308-313
    • Muenke, M.1    Schell, U.2
  • 75
    • 0026648812 scopus 로고
    • Kinetics of basic fibroblast growth factor binding to its receptor and heparan sulfate proteoglycan: A mechanism for cooperactivity
    • Nugent MA, Edelman ER. 1992. Kinetics of basic fibroblast growth factor binding to its receptor and heparan sulfate proteoglycan: A mechanism for cooperactivity. Biochemistry 31:8876-8883.
    • (1992) Biochemistry , vol.31 , pp. 8876-8883
    • Nugent, M.A.1    Edelman, E.R.2
  • 77
    • 84927912430 scopus 로고    scopus 로고
    • Hallmarks of alternative splicing in cancer
    • Epub ahead of print]
    • Oltean S, Bates DO. 2013. Hallmarks of alternative splicing in cancer. Oncogene. [Epub ahead of print]
    • (2013) Oncogene
    • Oltean, S.1    Bates, D.O.2
  • 78
    • 33749025816 scopus 로고    scopus 로고
    • Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity
    • Oltean S, Sorg BS, Albrecht T, Bonano VI, Brazas RM, Dewhirst MW, Garcia-Blanco MA. 2006. Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity. Proc Natl Acad Sci USA 103:14116-14121.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 14116-14121
    • Oltean, S.1    Sorg, B.S.2    Albrecht, T.3    Bonano, V.I.4    Brazas, R.M.5    Dewhirst, M.W.6    Garcia-Blanco, M.A.7
  • 80
    • 0033951768 scopus 로고    scopus 로고
    • FGFs, heparan sulfate and FGFRs: Complex interactions essential for development
    • Ornitz DM. 2000. FGFs, heparan sulfate and FGFRs: Complex interactions essential for development. Bioessays 22:108-112.
    • (2000) Bioessays , vol.22 , pp. 108-112
    • Ornitz, D.M.1
  • 83
    • 56749098074 scopus 로고    scopus 로고
    • Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
    • Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ. 2008. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat Genet 40:1413-1415.
    • (2008) Nat Genet , vol.40 , pp. 1413-1415
    • Pan, Q.1    Shai, O.2    Lee, L.J.3    Frey, B.J.4    Blencowe, B.J.5
  • 84
    • 70349125488 scopus 로고    scopus 로고
    • Co-transcriptional splicing of constitutive and alternative exons
    • Pandya-Jones A, Black DL. 2009. Co-transcriptional splicing of constitutive and alternative exons. RNA 15:1896-1908.
    • (2009) RNA , vol.15 , pp. 1896-1908
    • Pandya-Jones, A.1    Black, D.L.2
  • 85
    • 0034640103 scopus 로고    scopus 로고
    • Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity
    • Plotnikov AN, Hubbard SR, Schlessinger J, Mohammadi M. 2000. Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity. Cell 101:413-424.
    • (2000) Cell , vol.101 , pp. 413-424
    • Plotnikov, A.N.1    Hubbard, S.R.2    Schlessinger, J.3    Mohammadi, M.4
  • 86
    • 0033520472 scopus 로고    scopus 로고
    • Structural basis for FGF receptor dimerization and activation
    • Plotnikov AN, Schlessinger J, Hubbard SR, Mohammadi M. 1999. Structural basis for FGF receptor dimerization and activation. Cell 98:641-650.
    • (1999) Cell , vol.98 , pp. 641-650
    • Plotnikov, A.N.1    Schlessinger, J.2    Hubbard, S.R.3    Mohammadi, M.4
  • 88
    • 0028936927 scopus 로고
    • Regulation by heparan sulfate in fibroblast growth factor signaling
    • Rapraeger AC, Guimond S, Krufka A, Olwin BB. 1994. Regulation by heparan sulfate in fibroblast growth factor signaling. Methods Enzymol 245:219-240.
    • (1994) Methods Enzymol , vol.245 , pp. 219-240
    • Rapraeger, A.C.1    Guimond, S.2    Krufka, A.3    Olwin, B.B.4
  • 90
    • 33846574186 scopus 로고    scopus 로고
    • Prostate cells express two isoforms of fibroblast growth factor receptor 1 with different affinities for fibroblast growth factor-2
    • Roghani M, Moscatelli D. 2007. Prostate cells express two isoforms of fibroblast growth factor receptor 1 with different affinities for fibroblast growth factor-2. Prostate 67:115-124.
    • (2007) Prostate , vol.67 , pp. 115-124
    • Roghani, M.1    Moscatelli, D.2
  • 91
    • 0034118339 scopus 로고    scopus 로고
    • Normal human fibroblasts produce membrane-bound and soluble isoforms of FGFR-1
    • Root LL, Shipley GD. 2000. Normal human fibroblasts produce membrane-bound and soluble isoforms of FGFR-1. Mol Cell Biol Res Commun 3:87-97.
    • (2000) Mol Cell Biol Res Commun , vol.3 , pp. 87-97
    • Root, L.L.1    Shipley, G.D.2
  • 92
    • 0033899969 scopus 로고    scopus 로고
    • Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer
    • Ropiquet F, Giri D, Kwabi-Addo B, Mansukhani A, Ittmann M. 2000. Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer. Cancer Res 60:4245-4250.
    • (2000) Cancer Res , vol.60 , pp. 4245-4250
    • Ropiquet, F.1    Giri, D.2    Kwabi-Addo, B.3    Mansukhani, A.4    Ittmann, M.5
  • 93
    • 0028226196 scopus 로고
    • Soluble receptors for cytokines and growth factors: Generation and biological function
    • Rose-John S, Heinrich PC. 1994. Soluble receptors for cytokines and growth factors: Generation and biological function. Biochem J 300:281-290.
    • (1994) Biochem J , vol.300 , pp. 281-290
    • Rose-John, S.1    Heinrich, P.C.2
  • 94
    • 0033151612 scopus 로고    scopus 로고
    • FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway
    • Sahni M, Ambrosetti DC, Mansukhani A, Gertner R, Levy D, Basilico C. 1999. FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway. Genes Dev 13:1361-1366.
    • (1999) Genes Dev , vol.13 , pp. 1361-1366
    • Sahni, M.1    Ambrosetti, D.C.2    Mansukhani, A.3    Gertner, R.4    Levy, D.5    Basilico, C.6
  • 95
    • 0032827032 scopus 로고    scopus 로고
    • The acidic domain and first immunoglobulin-like loop of fibroblast growth factor receptor 2 modulate downstream signaling through glycosaminoglycan modification
    • Sakaguchi K, Lorenzi MV, Bottaro DP, Miki T. 1999. The acidic domain and first immunoglobulin-like loop of fibroblast growth factor receptor 2 modulate downstream signaling through glycosaminoglycan modification. Mol Cell Biol 19:6754-6764.
    • (1999) Mol Cell Biol , vol.19 , pp. 6754-6764
    • Sakaguchi, K.1    Lorenzi, M.V.2    Bottaro, D.P.3    Miki, T.4
  • 96
    • 0027992204 scopus 로고
    • Alternative splicing in fibroblast growth factor receptor 2 is associated with induced epithelial-mesenchymal transition in rat bladder carcinoma cells
    • Savagner P, Vallés AM, Jouanneau J, Yamada KM, Thiery JP. 1994. Alternative splicing in fibroblast growth factor receptor 2 is associated with induced epithelial-mesenchymal transition in rat bladder carcinoma cells. Mol Biol Cell 5(8):851-862.
    • (1994) Mol Biol Cell , vol.5 , Issue.8 , pp. 851-862
    • Savagner, P.1    Vallés, A.M.2    Jouanneau, J.3    Yamada, K.M.4    Thiery, J.P.5
  • 98
    • 0027196278 scopus 로고
    • Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants
    • Shi E, Kan M, Xu J, Wang F, Hou J, McKeehan W. 1993. Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants. Mol Cell Biol 13:3907-3918.
    • (1993) Mol Cell Biol , vol.13 , pp. 3907-3918
    • Shi, E.1    Kan, M.2    Xu, J.3    Wang, F.4    Hou, J.5    McKeehan, W.6
  • 99
    • 0035815704 scopus 로고    scopus 로고
    • A novel alternatively spliced fibroblast growth factor receptor 3 isoform lacking the acid box domain is expressed during chondrogenic differentiation of ATDC5 cells
    • Shimizu A, Tada K, Shukunami C, Hiraki Y, Kurokawa T, Magane N, Kurokawa-Seo M. 2001. A novel alternatively spliced fibroblast growth factor receptor 3 isoform lacking the acid box domain is expressed during chondrogenic differentiation of ATDC5 cells. J Biol Chem 276:11031-11040.
    • (2001) J Biol Chem , vol.276 , pp. 11031-11040
    • Shimizu, A.1    Tada, K.2    Shukunami, C.3    Hiraki, Y.4    Kurokawa, T.5    Magane, N.6    Kurokawa-Seo, M.7
  • 100
    • 0036291434 scopus 로고    scopus 로고
    • FGFR3 isoforms have distinct functions in the regulation of growth and cell morphology
    • Shimizu A, Takashima Y, Kurokawa-Seo M. 2002. FGFR3 isoforms have distinct functions in the regulation of growth and cell morphology. Biochem Biophys Res Commun 290:113-120.
    • (2002) Biochem Biophys Res Commun , vol.290 , pp. 113-120
    • Shimizu, A.1    Takashima, Y.2    Kurokawa-Seo, M.3
  • 101
    • 0034685038 scopus 로고    scopus 로고
    • Identification of a novel alternative splicing of human FGF receptor 4: soluble-form splice variant expressed in human gastrointestinal epithelial cells
    • Takaishi S, Sawada M, Morita Y, Seno H, Fukuzawa H, Chiba T. 2000. Identification of a novel alternative splicing of human FGF receptor 4: soluble-form splice variant expressed in human gastrointestinal epithelial cells. Biochem Biophys Res Commun 267:658-662.
    • (2000) Biochem Biophys Res Commun , vol.267 , pp. 658-662
    • Takaishi, S.1    Sawada, M.2    Morita, Y.3    Seno, H.4    Fukuzawa, H.5    Chiba, T.6
  • 102
    • 0035200948 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 lacking the Ig IIIb and transmembrane domains secreted from human squamous cell carcinoma DJM-1 binds to FGFs
    • Terada M, Shimizu A, Sato N, Miyakaze S-i, Katayama H, Kurokawa-Seo M. 2001. Fibroblast growth factor receptor 3 lacking the Ig IIIb and transmembrane domains secreted from human squamous cell carcinoma DJM-1 binds to FGFs. Mol Cell Biol Res Commun 4:365-373.
    • (2001) Mol Cell Biol Res Commun , vol.4 , pp. 365-373
    • Terada, M.1    Shimizu, A.2    Sato, N.3    Miyakaze, S.-I.4    Katayama, H.5    Kurokawa-Seo, M.6
  • 103
    • 0141617374 scopus 로고    scopus 로고
    • Developmental biology and building a tooth
    • Thesleff I. 2003. Developmental biology and building a tooth. Quintessence Int 34:613-620.
    • (2003) Quintessence Int , vol.34 , pp. 613-620
    • Thesleff, I.1
  • 104
    • 0035116502 scopus 로고    scopus 로고
    • Role of androgens and fibroblast growth factors in prostatic development
    • Thomson AA. 2001. Role of androgens and fibroblast growth factors in prostatic development. Reproduction 121:187-195.
    • (2001) Reproduction , vol.121 , pp. 187-195
    • Thomson, A.A.1
  • 105
    • 78149318726 scopus 로고    scopus 로고
    • Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer
    • Tomlinson DC, Knowles MA. 2010. Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer. Am J Pathol 177:2379-2386.
    • (2010) Am J Pathol , vol.177 , pp. 2379-2386
    • Tomlinson, D.C.1    Knowles, M.A.2
  • 107
    • 0026481988 scopus 로고
    • Fibroblast growth factor receptor-4 shows novel features in genomic structure, ligand binding and signal transduction
    • Vainikka S, Partanen J, Bellosta P, Coulier F, Birnbaum D, Basilico C, Jaye M, Alitalo K. 1992. Fibroblast growth factor receptor-4 shows novel features in genomic structure, ligand binding and signal transduction. EMBO J 11:4273-4280.
    • (1992) EMBO J , vol.11 , pp. 4273-4280
    • Vainikka, S.1    Partanen, J.2    Bellosta, P.3    Coulier, F.4    Birnbaum, D.5    Basilico, C.6    Jaye, M.7    Alitalo, K.8
  • 109
    • 0038258626 scopus 로고    scopus 로고
    • Ligand activation of alternatively spliced fibroblast growth factor receptor-1 modulates pancreatic adenocarcinoma cell malignancy
    • Vickers SM, Huang ZQ, MacMillan-Crow L, Greendorfer JS, Thompson JA. 2002. Ligand activation of alternatively spliced fibroblast growth factor receptor-1 modulates pancreatic adenocarcinoma cell malignancy. J Gastrointest Surg 6:546-553.
    • (2002) J Gastrointest Surg , vol.6 , pp. 546-553
    • Vickers, S.M.1    Huang, Z.Q.2    MacMillan-Crow, L.3    Greendorfer, J.S.4    Thompson, J.A.5
  • 111
    • 0028951147 scopus 로고
    • Ligand-specific structural domains in the fibroblast growth factor receptor
    • Wang F, Kan M, Xu J, Yan G, McKeehan WL. 1995. Ligand-specific structural domains in the fibroblast growth factor receptor. J Biol Chem 270:10222-10230.
    • (1995) J Biol Chem , vol.270 , pp. 10222-10230
    • Wang, F.1    Kan, M.2    Xu, J.3    Yan, G.4    McKeehan, W.L.5
  • 112
    • 0033524431 scopus 로고    scopus 로고
    • Common and specific determinants for fibroblast growth factors in the ectodomain of the receptor kinase complex
    • Wang F, Lu W, McKeehan K, Mohamedali K, Gabriel JL, Kan M, McKeehan WL. 1999. Common and specific determinants for fibroblast growth factors in the ectodomain of the receptor kinase complex. Biochemistry 38:160-171.
    • (1999) Biochemistry , vol.38 , pp. 160-171
    • Wang, F.1    Lu, W.2    McKeehan, K.3    Mohamedali, K.4    Gabriel, J.L.5    Kan, M.6    McKeehan, W.L.7
  • 114
    • 84866320228 scopus 로고    scopus 로고
    • Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT)
    • Warzecha CC, Carstens RP. 2012. Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT). Semin Cancer Biol 22:417-427.
    • (2012) Semin Cancer Biol , vol.22 , pp. 417-427
    • Warzecha, C.C.1    Carstens, R.P.2
  • 116
    • 61649087689 scopus 로고    scopus 로고
    • ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing
    • Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP. 2009. ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell 33:591-601.
    • (2009) Mol Cell , vol.33 , pp. 591-601
    • Warzecha, C.C.1    Sato, T.K.2    Nabet, B.3    Hogenesch, J.B.4    Carstens, R.P.5
  • 117
    • 77950552549 scopus 로고    scopus 로고
    • The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events
    • Warzecha CC, Shen S, Xing Y, Carstens RP. 2009. The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events. RNA Biol 6:546-562.
    • (2009) RNA Biol , vol.6 , pp. 546-562
    • Warzecha, C.C.1    Shen, S.2    Xing, Y.3    Carstens, R.P.4
  • 118
    • 0026514045 scopus 로고
    • Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities
    • Werner S, Duan DS, de Vries C, Peters KG, Johnson DE, Williams LT. 1992. Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities. Mol Cell Biol 12:82-88.
    • (1992) Mol Cell Biol , vol.12 , pp. 82-88
    • Werner, S.1    Duan, D.S.2    de Vries, C.3    Peters, K.G.4    Johnson, D.E.5    Williams, L.T.6
  • 119
    • 79959713140 scopus 로고    scopus 로고
    • Fibroblast growth factors and their receptors in cancer
    • Wesche J, Haglund K, Haugsten E. 2011. Fibroblast growth factors and their receptors in cancer. Biochem J 437:199-213.
    • (2011) Biochem J , vol.437 , pp. 199-213
    • Wesche, J.1    Haglund, K.2    Haugsten, E.3
  • 120
    • 79955539972 scopus 로고    scopus 로고
    • Identification and characterization of an inhibitory fibroblast growth factor receptor 2 (FGFR2) molecule, up-regulated in an Apert Syndrome mouse model
    • Wheldon LM, Khodabukus N, Patey SJ, Smith TG, Heath JK, Hajihosseini MK. 2011. Identification and characterization of an inhibitory fibroblast growth factor receptor 2 (FGFR2) molecule, up-regulated in an Apert Syndrome mouse model. Biochemical J 436:71-81.
    • (2011) Biochemical J , vol.436 , pp. 71-81
    • Wheldon, L.M.1    Khodabukus, N.2    Patey, S.J.3    Smith, T.G.4    Heath, J.K.5    Hajihosseini, M.K.6
  • 121
    • 17844402791 scopus 로고    scopus 로고
    • Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations
    • Wilkie AO. 2005. Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations. Cytokine Growth Factor Rev 16:187-203.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 187-203
    • Wilkie, A.O.1
  • 122
    • 0026648983 scopus 로고
    • Expression and immunochemical analysis of rat and human fibroblast growth factor receptor (flg) isoforms
    • Xu J, Nakahara M, Crabb JW, Shi E, Matuo Y, Fraser M, Kan M, Hou J, McKeehan WL. 1992. Expression and immunochemical analysis of rat and human fibroblast growth factor receptor (flg) isoforms. J Biol Chem 267:17792-17803.
    • (1992) J Biol Chem , vol.267 , pp. 17792-17803
    • Xu, J.1    Nakahara, M.2    Crabb, J.W.3    Shi, E.4    Matuo, Y.5    Fraser, M.6    Kan, M.7    Hou, J.8    McKeehan, W.L.9
  • 123
    • 0033524455 scopus 로고    scopus 로고
    • A bioluminescence resonance energy transfer (BRET) system: Application to interacting circadian clock proteins
    • Xu Y, Piston DW, Johnson CH. 1999. A bioluminescence resonance energy transfer (BRET) system: Application to interacting circadian clock proteins. Proc Natl Acad Sci USA 96:151-156.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 151-156
    • Xu, Y.1    Piston, D.W.2    Johnson, C.H.3
  • 124
    • 0028096172 scopus 로고
    • Differential expression of two fibroblast growth factor-receptor genes is associated with malignant progression in human astrocytomas
    • Yamaguchi F, Saya H, Bruner JM, Morrison RS. 1994. Differential expression of two fibroblast growth factor-receptor genes is associated with malignant progression in human astrocytomas. Proc Natl Acad Sci 91:484-488.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 484-488
    • Yamaguchi, F.1    Saya, H.2    Bruner, J.M.3    Morrison, R.S.4
  • 125
    • 0027198248 scopus 로고
    • Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy
    • Yan G, Fukabori Y, McBride G, Nikolaropolous S, McKeehan WL. 1993. Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy. Mol Cell Biol 13:4513-4522.
    • (1993) Mol Cell Biol , vol.13 , pp. 4513-4522
    • Yan, G.1    Fukabori, Y.2    McBride, G.3    Nikolaropolous, S.4    McKeehan, W.L.5
  • 126
    • 0025976838 scopus 로고
    • Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor
    • Yayon A, Klagsbrun M, Esko JD, Leder P, Ornitz DM. 1991. Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell 64:841-848.
    • (1991) Cell , vol.64 , pp. 841-848
    • Yayon, A.1    Klagsbrun, M.2    Esko, J.D.3    Leder, P.4    Ornitz, D.M.5
  • 127
    • 16244416568 scopus 로고    scopus 로고
    • Keratinocyte growth factor receptor expression in normal colorectal epithelial cells and differentiated type of colorectal cancer
    • Yoshino M, Ishiwata T, Watanabe M, Komine O, Shibuya T, Tokunaga A, Naito Z. 2005. Keratinocyte growth factor receptor expression in normal colorectal epithelial cells and differentiated type of colorectal cancer. Oncol Rep 13:247-252.
    • (2005) Oncol Rep , vol.13 , pp. 247-252
    • Yoshino, M.1    Ishiwata, T.2    Watanabe, M.3    Komine, O.4    Shibuya, T.5    Tokunaga, A.6    Naito, Z.7
  • 128
    • 0035957378 scopus 로고    scopus 로고
    • Uncoupling fibroblast growth factor receptor 2 ligand binding specificity leads to Apert syndrome-like phenotypes
    • Yu K, Ornitz DM. 2001. Uncoupling fibroblast growth factor receptor 2 ligand binding specificity leads to Apert syndrome-like phenotypes. Proc Natl Acad Sci USA 98:3641-3643.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3641-3643
    • Yu, K.1    Ornitz, D.M.2
  • 129
    • 33646861363 scopus 로고    scopus 로고
    • Alternatively spliced FGFR-1 isoforms differentially modulate endothelial cell activation of c-YES
    • Zhang P, Greendorfer JS, Jiao J, Kelpke SC, Thompson JA. 2006. Alternatively spliced FGFR-1 isoforms differentially modulate endothelial cell activation of c-YES. Arch Biochem Biophys 450:50-62.
    • (2006) Arch Biochem Biophys , vol.450 , pp. 50-62
    • Zhang, P.1    Greendorfer, J.S.2    Jiao, J.3    Kelpke, S.C.4    Thompson, J.A.5
  • 130
    • 0033119157 scopus 로고    scopus 로고
    • Genomic organization of the human fibroblast growth factor receptor 2 (FGFR2) gene and comparative analysis of the human FGFR gene family
    • Zhang Y, Gorry MC, Post JC, Ehrlich GD. 1999. Genomic organization of the human fibroblast growth factor receptor 2 (FGFR2) gene and comparative analysis of the human FGFR gene family. Gene 230:69-79.
    • (1999) Gene , vol.230 , pp. 69-79
    • Zhang, Y.1    Gorry, M.C.2    Post, J.C.3    Ehrlich, G.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.