-
1
-
-
0035114558
-
Cancer statistics, 2001
-
Greenlee, R.T.; Murray, T.; Hill-Harmon, M.B.; Thun, M.J. Cancer statistics, 2001. CA: Cancer J. Clin. 2001, 51, 15-36.
-
(2001)
CA: Cancer J. Clin.
, vol.51
, pp. 15-36
-
-
Greenlee, R.T.1
Murray, T.2
Hill-Harmon, M.B.3
Thun, M.J.4
-
2
-
-
0036065012
-
Patterns and trends in prostate cancer incidence, survival, prevalence and mortality. Part I: International comparisons
-
Quinn, M.; Babb, P. Patterns and trends in prostate cancer incidence, survival, prevalence and mortality. Part I: International comparisons. BJU Int. 2002, 90, 162-173.
-
(2002)
BJU Int.
, vol.90
, pp. 162-173
-
-
Quinn, M.1
Babb, P.2
-
3
-
-
0037426058
-
Prostate cancer epidemiology
-
Gronberg, H. Prostate cancer epidemiology. Lancet 2003, 361, 859-864.
-
(2003)
Lancet
, vol.361
, pp. 859-864
-
-
Gronberg, H.1
-
4
-
-
0003964363
-
-
American Cancer Society American Cancer Society: Atlanta, GA, USA
-
American Cancer Society. Cancer Facts & Figures 2003; American Cancer Society: Atlanta, GA, USA, 2003.
-
(2003)
Cancer Facts & Figures 2003
-
-
-
5
-
-
0025651177
-
Family history and the risk of prostate cancer
-
Steinberg, G.D.; Carter, B.S.; Beaty, T.H.; Childs, B.; Walsh, P.C. Family history and the risk of prostate cancer. Prostate 1990, 17, 337-347.
-
(1990)
Prostate
, vol.17
, pp. 337-347
-
-
Steinberg, G.D.1
Carter, B.S.2
Beaty, T.H.3
Childs, B.4
Walsh, P.C.5
-
6
-
-
0036717993
-
Hereditary prostate cancer: Clinical aspects
-
Bratt, O. Hereditary prostate cancer: Clinical aspects. J. Urol. 2002, 168, 906-913.
-
(2002)
J. Urol.
, vol.168
, pp. 906-913
-
-
Bratt, O.1
-
7
-
-
0028952799
-
Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada
-
Whittemore, A.; Kolonel, L.N.; Wu, A.H.; John, E.M.; Gallagher, R.P.; Howe, G.R.; Burch, J.D.; Hankin, J.; Dreon, D.M.; West, D.W. Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J. Natl. Cancer Inst. 1995, 87, 652-661.
-
(1995)
J. Natl. Cancer Inst.
, vol.87
, pp. 652-661
-
-
Whittemore, A.1
Kolonel, L.N.2
Wu, A.H.3
John, E.M.4
Gallagher, R.P.5
Howe, G.R.6
Burch, J.D.7
Hankin, J.8
Dreon, D.M.9
West, D.W.10
-
8
-
-
0028696273
-
Role of androgens in prostatic cancer
-
Isaacs, J.T. Role of androgens in prostatic cancer. Vitam. Horm. 1994, 49, 433-502.
-
(1994)
Vitam. Horm.
, vol.49
, pp. 433-502
-
-
Isaacs, J.T.1
-
9
-
-
0031007690
-
Prostate cancer diagnosis and management
-
Frydenberg, M.; Stricker, P.D.; Kaye, K.W. Prostate cancer diagnosis and management. Lancet 1997, 349, 1681-1687.
-
(1997)
Lancet
, vol.349
, pp. 1681-1687
-
-
Frydenberg, M.1
Stricker, P.D.2
Kaye, K.W.3
-
10
-
-
0037612210
-
The management of high risk prostate cancer
-
Akduman, B.; Crawford, E.D. The management of high risk prostate cancer. J. Urol. 2003, 169, 1993-1998.
-
(2003)
J. Urol.
, vol.169
, pp. 1993-1998
-
-
Akduman, B.1
Crawford, E.D.2
-
11
-
-
0009829895
-
Studies on prostatic cancer. I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. 1941
-
Huggins, C.; Hodges, C.V. Studies on prostatic cancer. I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. 1941. J. Urol. 2002, 167, 948-951.
-
(2002)
J. Urol.
, vol.167
, pp. 948-951
-
-
Huggins, C.1
Hodges, C.V.2
-
12
-
-
0032860893
-
Chemotherapy in advanced prostate cancer
-
Beedassy, A.; Cardi, G. Chemotherapy in advanced prostate cancer. Semin. Oncol. 1999, 26, 428-438.
-
(1999)
Semin. Oncol.
, vol.26
, pp. 428-438
-
-
Beedassy, A.1
Cardi, G.2
-
13
-
-
0029873670
-
Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer
-
Denmeade, S.R.; Lin, X.S.; Isaacs, J.T. Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer. Prostate 1996, 28, 251-265.
-
(1996)
Prostate
, vol.28
, pp. 251-265
-
-
Denmeade, S.R.1
Lin, X.S.2
Isaacs, J.T.3
-
14
-
-
0030772022
-
Target to apoptosis: A hopeful weapon for prostate cancer
-
Tang, D.G.; Porter, A.T. Target to apoptosis: A hopeful weapon for prostate cancer. Prostate 1997, 32, 284-293.
-
(1997)
Prostate
, vol.32
, pp. 284-293
-
-
Tang, D.G.1
Porter, A.T.2
-
15
-
-
0033215472
-
Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process
-
Craft, N.; Chhor, C.; Tran, C.; Belldegrun, A.; DeKernion, J.; Witte, O.N.; Said, J.; Reiter, R.E.; Sawyers, C.L. Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process. Cancer Res. 1999, 59, 5030-5036.
-
(1999)
Cancer Res.
, vol.59
, pp. 5030-5036
-
-
Craft, N.1
Chhor, C.2
Tran, C.3
Belldegrun, A.4
DeKernion, J.5
Witte, O.N.6
Said, J.7
Reiter, R.E.8
Sawyers, C.L.9
-
16
-
-
84871640543
-
Synthesis and preliminary evaluation of pharmacological properties of some piperazine derivatives of xanthone
-
Szkaradek, N.; Rapacz, A.; Pytka, K.; Filipek, B.; Siwek, A.; Cegła, M.; Marona, H. Synthesis and preliminary evaluation of pharmacological properties of some piperazine derivatives of xanthone. Bioorg. Med. Chem. 2013, 21, 514-522.
-
(2013)
Bioorg. Med. Chem.
, vol.21
, pp. 514-522
-
-
Szkaradek, N.1
Rapacz, A.2
Pytka, K.3
Filipek, B.4
Siwek, A.5
Cegła, M.6
Marona, H.7
-
17
-
-
0027393740
-
O-Chlorobenzenesulfonamidic derivatives of (aryloxy)propanolamines as beta-blocking/diuretic agents
-
Cecchetti, V; Fravolini, A.; Schiaffella, F.; Tabarrini, O.; Bruni, G.; Segret, G. O-Chlorobenzenesulfonamidic derivatives of (aryloxy)propanolamines as beta-blocking/diuretic agents. J. Med. Chem. 1993, 36, 157-161.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 157-161
-
-
Cecchetti, V.1
Fravolini, A.2
Schiaffella, F.3
Tabarrini, O.4
Bruni, G.5
Segret, G.6
-
18
-
-
0025316409
-
The synthesis and antiallergy activity of 1-(aryloxy)-4-(4- arylpiperazinyl)-2-butanol derivatives
-
Walsh, D.A.; Chen, Y.H.; Green, J.B.; Nolan, J.C.; Yannit, J.M. The synthesis and antiallergy activity of 1-(aryloxy)-4-(4-arylpiperazinyl)-2- butanol derivatives. J. Med. Chem. 1990, 33, 1823-1827.
-
(1990)
J. Med. Chem.
, vol.33
, pp. 1823-1827
-
-
Walsh, D.A.1
Chen, Y.H.2
Green, J.B.3
Nolan, J.C.4
Yannit, J.M.5
-
19
-
-
80052790873
-
Design and synthesis of novel arylpiperazine derivatives containing the imidazole core targeting 5-HT(2A) receptor and 5-HT transporter
-
Seo, HJ.; Park, E.J.; Kim, M.J.; Kang, S.Y.; Lee, S.H.; Kim, H.J.; Lee, K.N.; Jung, M.E.; Lee, M.; Kim, M.S.; et al. Design and synthesis of novel arylpiperazine derivatives containing the imidazole core targeting 5-HT(2A) receptor and 5-HT transporter. J. Med. Chem. 2011, 54, 6305-6318.
-
(2011)
J. Med. Chem.
, vol.54
, pp. 6305-6318
-
-
Seo, H.J.1
Park, E.J.2
Kim, M.J.3
Kang, S.Y.4
Lee, S.H.5
Kim, H.J.6
Lee, K.N.7
Jung, M.E.8
Lee, M.9
Kim, M.S.10
-
20
-
-
0020682795
-
Synthesis and antianxiety activity of (omega-piperazinylalkoxy)indan derivatives
-
Kikumoto, R.; Tobe, A.; Fukami, H.; Egawa, M. Synthesis and antianxiety activity of (omega-piperazinylalkoxy)indan derivatives. J. Med. Chem. 1983, 26, 246-250.
-
(1983)
J. Med. Chem.
, vol.26
, pp. 246-250
-
-
Kikumoto, R.1
Tobe, A.2
Fukami, H.3
Egawa, M.4
-
21
-
-
0023706680
-
Dopamine autoreceptor agonists as potential antipsychotics. 1. (Aminoalkoxy)anilines
-
Jaen, J.C.; Wise, L.D.; Heffner, T.G.; Pugsley, T.A.; Meltzed, L.T. Dopamine autoreceptor agonists as potential antipsychotics. 1. (Aminoalkoxy)anilines. J. Med. Chem. 1988, 31, 1621-1625.
-
(1988)
J. Med. Chem.
, vol.31
, pp. 1621-1625
-
-
Jaen, J.C.1
Wise, L.D.2
Heffner, T.G.3
Pugsley, T.A.4
Meltzed, L.T.5
-
22
-
-
84055211848
-
Synthesis, antimalarial activity, and structure-activity relationship of 7-(2-phenoxyethoxy)-4(1H)-quinolones
-
Cross, R.M.; Namelikonda, N.K.; Mutka, T.S.; Luong, L.; Kyle, D.E.; Manetsch, R. Synthesis, antimalarial activity, and structure-activity relationship of 7-(2-phenoxyethoxy)-4(1H)-quinolones. J. Med. Chem. 2011, 54, 8321-8327.
-
(2011)
J. Med. Chem.
, vol.54
, pp. 8321-8327
-
-
Cross, R.M.1
Namelikonda, N.K.2
Mutka, T.S.3
Luong, L.4
Kyle, D.E.5
Manetsch, R.6
-
23
-
-
0041333074
-
Synthesis of totarol amino alcohol derivatives and their antiplasmodial activity and cytotoxicity
-
Clarkson, C.; Musonda, C.C.; Chibale, K.; Campbella, W.E.; Smitha, P. Synthesis of totarol amino alcohol derivatives and their antiplasmodial activity and cytotoxicity. Bioorg. Med. Chem. 2003, 11, 4417-4422.
-
(2003)
Bioorg. Med. Chem.
, vol.11
, pp. 4417-4422
-
-
Clarkson, C.1
Musonda, C.C.2
Chibale, K.3
Campbella, W.E.4
Smitha, P.5
-
24
-
-
34948864356
-
4-[omega-[4-arylpiperazin-1-yl]alkoxy]phenyl)imidazo[1,2-a]pyridine derivatives: Fluorescent high-affinity dopamine D3 receptor ligands as potential probes for receptor visualization
-
Leopoldo, M.; Lacivita, E.; Passafiume, E.; Contino, M.; Colabufo, N.A.; Berardi, F.; Perrone, R. 4-[omega-[4-arylpiperazin-1-yl]alkoxy]phenyl)imidazo[1, 2-a]pyridine derivatives: Fluorescent high-affinity dopamine D3 receptor ligands as potential probes for receptor visualization. J. Med. Chem. 2007, 50, 5043-5047.
-
(2007)
J. Med. Chem.
, vol.50
, pp. 5043-5047
-
-
Leopoldo, M.1
Lacivita, E.2
Passafiume, E.3
Contino, M.4
Colabufo, N.A.5
Berardi, F.6
Perrone, R.7
-
25
-
-
84866934645
-
2 receptor agonists
-
2 receptor agonists. J. Med. Chem. 2012, 55, 7141-7153.
-
(2012)
J. Med. Chem.
, vol.55
, pp. 7141-7153
-
-
Chen, X.1
Sassano, M.F.2
Zheng, L.Y.3
Setola, V.4
Chen, M.5
Bai, X.6
Frye, S.V.7
Wetsel, W.C.8
Roth, B.L.9
Jin, J.10
-
26
-
-
79957505587
-
Discovery of LASSBio-772, a 1,3-benzodioxole N-phenylpiperazine derivative with potent alpha 1A/D-adrenergic receptor blocking properties
-
Romeiro, L.A.; da Silva Ferreira, M.; da Silva, L.L.; Castro, H.C.; Miranda, A.L.; Silva, C.L.; Noël, F.; Nascimento, J.B.; Araújo, C.V.; Tibiriçá, E.; et al. Discovery of LASSBio-772, a 1,3-benzodioxole N-phenylpiperazine derivative with potent alpha 1A/D-adrenergic receptor blocking properties. Eur. J. Med. Chem. 2011, 46, 3000-3012.
-
(2011)
Eur. J. Med. Chem.
, vol.46
, pp. 3000-3012
-
-
Romeiro, L.A.1
Da Silva Ferreira, M.2
Da Silva, L.L.3
Castro, H.C.4
Miranda, A.L.5
Silva, C.L.6
Noël, F.7
Nascimento, J.B.8
Araújo, C.V.9
Tibiriç á, E.10
-
27
-
-
84898754977
-
Studies on novel pyridine and 2-pyridone derivatives of N-arylpiperazine as α-adrenoceptor ligands
-
Baran, M.; Kepczynska, E.; Zylewski, M.; Siwek, A.; Bednarski, M.; Cegla, M.T. Studies on novel pyridine and 2-pyridone derivatives of N-arylpiperazine as α-adrenoceptor ligands. Med. Chem. 2014, 10, 144-153.
-
(2014)
Med. Chem.
, vol.10
, pp. 144-153
-
-
Baran, M.1
Kepczynska, E.2
Zylewski, M.3
Siwek, A.4
Bednarski, M.5
Cegla, M.T.6
-
28
-
-
0242692630
-
Efficacy of tamsulosin in the medical management of juxtavesical ureteral stones
-
Dellabella, M.; Milanese, G.; Muzzonigro, G. Efficacy of tamsulosin in the medical management of juxtavesical ureteral stones. J. Urol. 2003, 170, 2202-2205.
-
(2003)
J. Urol.
, vol.170
, pp. 2202-2205
-
-
Dellabella, M.1
Milanese, G.2
Muzzonigro, G.3
-
29
-
-
0023272659
-
Ureteral urine transport: Changes in bolus volume, peristaltic frequency, intraluminal pressure and volume of flow resulting from autonomic drugs
-
Morita, T.; Wada, I.; Saeki, H.; Tsuchida, S.; Weiss, R.M. Ureteral urine transport: Changes in bolus volume, peristaltic frequency, intraluminal pressure and volume of flow resulting from autonomic drugs. J. Urol. 1987, 137, 132-135.
-
(1987)
J. Urol.
, vol.137
, pp. 132-135
-
-
Morita, T.1
Wada, I.2
Saeki, H.3
Tsuchida, S.4
Weiss, R.M.5
-
30
-
-
0032587629
-
Naftopidil, a novel alpha1-adrenoceptor antagonist, displays selective inhibition of canine prostatic pressure and high affinity binding to cloned human alpha1-adrenoceptors
-
Takei, R.; Ikegaki, I.; Shibata, K.; Tsujimoto, G.; Asano, T. Naftopidil, a novel alpha1-adrenoceptor antagonist, displays selective inhibition of canine prostatic pressure and high affinity binding to cloned human alpha1-adrenoceptors. Jpn. J. Pharmacol. 1999, 79, 447-454.
-
(1999)
Jpn. J. Pharmacol.
, vol.79
, pp. 447-454
-
-
Takei, R.1
Ikegaki, I.2
Shibata, K.3
Tsujimoto, G.4
Asano, T.5
-
31
-
-
33644897341
-
Comparison of two alpha1-adrenoceptor antagonists, naftopidil and tamsulosin hydrochloride, in the treatment of lower urinary tract symptoms with benign prostatic hyperplasia: A randomized crossover study
-
Nishino, Y.; Masue, T.; Miwa, K.; Takahashi, Y.; Ishihara, S.; Deguchi, T. Comparison of two alpha1-adrenoceptor antagonists, naftopidil and tamsulosin hydrochloride, in the treatment of lower urinary tract symptoms with benign prostatic hyperplasia: A randomized crossover study. BJU Int. 2006, 97, 747-751.
-
(2006)
BJU Int.
, vol.97
, pp. 747-751
-
-
Nishino, Y.1
Masue, T.2
Miwa, K.3
Takahashi, Y.4
Ishihara, S.5
Deguchi, T.6
-
32
-
-
39149134906
-
Expression of alpha1-adrenoceptor subtype mRNA as a predictor of the efficacy of subtype selective alpha1-adrenoceptor antagonists in the management of benign prostatic hyperplasia
-
Kojima, Y.; Sasaki, S.; Kubota, Y.; Hayase, M.; Hayashi, Y.; Shinoura, H.; Tsujimoto, G.; Kohri, K. Expression of alpha1-adrenoceptor subtype mRNA as a predictor of the efficacy of subtype selective alpha1-adrenoceptor antagonists in the management of benign prostatic hyperplasia. J. Urol. 2008, 179, 1040-1046.
-
(2008)
J. Urol.
, vol.179
, pp. 1040-1046
-
-
Kojima, Y.1
Sasaki, S.2
Kubota, Y.3
Hayase, M.4
Hayashi, Y.5
Shinoura, H.6
Tsujimoto, G.7
Kohri, K.8
-
33
-
-
78650841605
-
Naftopidil, a selective {alpha}1-adrenoceptor antagonist, suppresses human prostate tumor growth by altering interactions between tumor cells and stroma
-
Hori, Y.; Ishii, K.; Kanda, H.; Iwamoto, Y.; Nishikawa, K.; Soga, N.; Kise, H.; Arima, K.; Sugimura, Y. Naftopidil, a selective {alpha}1-adrenoceptor antagonist, suppresses human prostate tumor growth by altering interactions between tumor cells and stroma. Cancer Prev. Res (Phila). 2011, 4, 87-96.
-
(2011)
Cancer Prev. Res (Phila)
, vol.4
, pp. 87-96
-
-
Hori, Y.1
Ishii, K.2
Kanda, H.3
Iwamoto, Y.4
Nishikawa, K.5
Soga, N.6
Kise, H.7
Arima, K.8
Sugimura, Y.9
-
34
-
-
36849034109
-
Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest
-
Kanda, H.; Ishii, K.; Ogura, Y.; Imamura, T.; Kanai, M.; Arima, K.; Sugimura, Y. Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest. Int. J. Cancer 2008, 122, 444-451.
-
(2008)
Int. J. Cancer
, vol.122
, pp. 444-451
-
-
Kanda, H.1
Ishii, K.2
Ogura, Y.3
Imamura, T.4
Kanai, M.5
Arima, K.6
Sugimura, Y.7
-
35
-
-
84866488801
-
Antitumor action of α(1)-adrenoceptor blockers on human bladder, prostate and renal cancer cells
-
Gotoh, A.; Nagaya, H.; Kanno, T.; Nishizaki, T. Antitumor action of α(1)-adrenoceptor blockers on human bladder, prostate and renal cancer cells. Pharmacology 2012, 90, 242-246.
-
(2012)
Pharmacology
, vol.90
, pp. 242-246
-
-
Gotoh, A.1
Nagaya, H.2
Kanno, T.3
Nishizaki, T.4
-
36
-
-
84875899823
-
Naftopidil induces apoptosis in malignant mesothelioma cell lines independently of α1-adrenoceptor blocking
-
Masachika, E.; Kanno, T.; Nakano, T.; Gotoh, A.; Nishizaki, T. Naftopidil induces apoptosis in malignant mesothelioma cell lines independently of α1-adrenoceptor blocking. Anticancer Res. 2013, 33, 887-894.
-
(2013)
Anticancer Res.
, vol.33
, pp. 887-894
-
-
Masachika, E.1
Kanno, T.2
Nakano, T.3
Gotoh, A.4
Nishizaki, T.5
-
37
-
-
33847066217
-
1-Arylpiperazinyl-4-cyclohexylamine derived isoindole-1,3-diones as potent and selective alpha-1a/1d adrenergic receptor ligands
-
Li, S.; Chiu, G.; Pulito, V.L.; Liu, J.; Connolly, P.J.; Middleton, S.A. 1-Arylpiperazinyl-4-cyclohexylamine derived isoindole-1,3-diones as potent and selective alpha-1a/1d adrenergic receptor ligands. Bioorg. Med. Chem. Lett. 2007, 17, 1646-1650.
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 1646-1650
-
-
Li, S.1
Chiu, G.2
Pulito, V.L.3
Liu, J.4
Connolly, P.J.5
Middleton, S.A.6
-
38
-
-
34249299761
-
(Arylpiperazinyl)cyclohexylsufonamides: Discovery of alpha(1a/1d)- selective adrenergic receptor antagonists for the treatment of benign prostatic Hyperplasia/lower Urinary tract symptoms (BPH/LUTS)
-
Chiu, G.; Li, S.; Connolly, P.J.; Pulito, V.; Liu, J.; Middleton, S.A. (Arylpiperazinyl)cyclohexylsufonamides: Discovery of alpha(1a/1d)-selective adrenergic receptor antagonists for the treatment of Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms (BPH/LUTS). Bioorg. Med. Chem. Lett. 2007, 17, 3292-3297.
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 3292-3297
-
-
Chiu, G.1
Li, S.2
Connolly, P.J.3
Pulito, V.4
Liu, J.5
Middleton, S.A.6
-
39
-
-
0033869072
-
Design, synthesis and biological evaluation of pyridine- phenylpiperazines: A novel series of potent and selective alpha1a-adrenergic receptor antagonist
-
Kuo, G.H.; Prouty, C.; Murray, W.V.; Pulito, V.; Jolliffe, L.; Cheung, P.; Varga, S.; Evangelisto, M.; Shaw, C. Design, synthesis and biological evaluation of pyridine-phenylpiperazines: A novel series of potent and selective alpha1a-adrenergic receptor antagonist. Bioorg. Med. Chem. 2000, 8, 2263-2275.
-
(2000)
Bioorg. Med. Chem.
, vol.8
, pp. 2263-2275
-
-
Kuo, G.H.1
Prouty, C.2
Murray, W.V.3
Pulito, V.4
Jolliffe, L.5
Cheung, P.6
Varga, S.7
Evangelisto, M.8
Shaw, C.9
-
40
-
-
0037009283
-
Arylpiperazine substituted heterocycles as selective alpha(1a) adrenergic antagonists
-
Khatuya, H.; Hutchings, R.H.; Kuo, G.H.; Pulito, V.L.; Jolliffe, L.K.; Li, X.; Murray, W.V. Arylpiperazine substituted heterocycles as selective alpha(1a) adrenergic antagonists. Bioorg. Med. Chem. Lett. 2002, 12, 2443-2446.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 2443-2446
-
-
Khatuya, H.1
Hutchings, R.H.2
Kuo, G.H.3
Pulito, V.L.4
Jolliffe, L.K.5
Li, X.6
Murray, W.V.7
-
41
-
-
17444425758
-
Synthesis and structure-activity relationship of fluoro analogues of 8-{2-[4-(4-methoxyphenyl)piperazin-1yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione as selective alpha(1d)-adrenergic receptor antagonists
-
Konkel, M.J.; Wetzel, J.M.; Cahir, M.; Craig, D.A.; Noble, S.A.; Gluchowski, C. Synthesis and structure-activity relationship of fluoro analogues of 8-{2-[4-(4-methoxyphenyl)piperazin-1yl]ethyl}-8-azaspiro[4.5]decane-7,9- dione as selective alpha(1d)-adrenergic receptor antagonists. J. Med. Chem. 2005, 48, 3076-3079.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 3076-3079
-
-
Konkel, M.J.1
Wetzel, J.M.2
Cahir, M.3
Craig, D.A.4
Noble, S.A.5
Gluchowski, C.6
-
42
-
-
79957511285
-
1-adrenoceptor subtypes
-
1- adrenoceptor subtypes. Eur. J. Med. Chem. 2011, 46, 2676-2690.
-
(2011)
Eur. J. Med. Chem.
, vol.46
, pp. 2676-2690
-
-
Romeo, G.1
Materia, L.2
Modica, M.N.3
Pittalà, V.4
Salerno, L.5
Siracusa, M.A.6
Manetti, F.7
Botta, M.8
Minneman, K.P.9
-
43
-
-
84906729118
-
Design, synthesis and α1-adrenoreceptor blocking activity of new arylpiperazines containing acetophenone substituents
-
Huang, J.J.; Huang, Y.J.; Zhu, L.; Yuan, M. Design, synthesis and α1-adrenoreceptor blocking activity of new arylpiperazines containing acetophenone substituents. Pharmazie 2014, 69, 1-7.
-
(2014)
Pharmazie
, vol.69
, pp. 1-7
-
-
Huang, J.J.1
Huang, Y.J.2
Zhu, L.3
Yuan, M.4
-
44
-
-
84867403701
-
Determination of naftopidil enantiomers in rat plasma using chiral solid phases and pre-column derivatization high-performance liquid chromatography
-
Liu, X.W.; Zhang, Y.Y.; Yuan, M.; Sun, Y.X. Determination of naftopidil enantiomers in rat plasma using chiral solid phases and pre-column derivatization high-performance liquid chromatography. J. Chromatogr. B 2012, 907, 140-145.
-
(2012)
J. Chromatogr. B
, vol.907
, pp. 140-145
-
-
Liu, X.W.1
Zhang, Y.Y.2
Yuan, M.3
Sun, Y.X.4
-
45
-
-
80055053451
-
Comparative Molecular Field Analysis (CoMFA) and Comparative Molecular Similarity Indices Analysis (CoMSIA) studies on α(1A)-adrenergic receptor antagonists based on pharmacophore molecular alignment
-
Zhao, X.; Chen, M.S.; Huang, B.Y.; Ji, H.; Yuan, M. Comparative Molecular Field Analysis (CoMFA) and Comparative Molecular Similarity Indices Analysis (CoMSIA) studies on α(1A)-adrenergic receptor antagonists based on pharmacophore molecular alignment. Int. J. Mol. Sci. 2011, 12, 7022-7037.
-
(2011)
Int. J. Mol. Sci.
, vol.12
, pp. 7022-7037
-
-
Zhao, X.1
Chen, M.S.2
Huang, B.Y.3
Ji, H.4
Yuan, M.5
-
46
-
-
77956283364
-
Ligand-based pharmacophore model of N-Aryl and N-Heteroaryl piperazine alpha 1A-adrenoceptors antagonists using GALAHAD
-
Zhao, X.; Yuan, M.; Huang, B.Y.; Ji, H.; Zhu, L. Ligand-based pharmacophore model of N-Aryl and N-Heteroaryl piperazine alpha 1A-adrenoceptors antagonists using GALAHAD. J. Mol. Graph. Model. 2010, 29, 126-136.
-
(2010)
J. Mol. Graph. Model.
, vol.29
, pp. 126-136
-
-
Zhao, X.1
Yuan, M.2
Huang, B.Y.3
Ji, H.4
Zhu, L.5
-
47
-
-
0030815118
-
In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia
-
Kaspers, G.J.; Veerman, A.J.; Pieters, R.; van Zantwijk, C.H.; Smets, L.A.; van Wering, E.R.; van der Does-Van Den Berg, A. In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia. Blood 1997, 90, 2723-2729.
-
(1997)
Blood
, vol.90
, pp. 2723-2729
-
-
Kaspers, G.J.1
Veerman, A.J.2
Pieters, R.3
Van Zantwijk, C.H.4
Smets, L.A.5
Van Wering, E.R.6
Van Der Does-Van Den Berg, A.7
-
48
-
-
0032126675
-
Prednisolone resistance in childhood acute lymphoblastic leukemia: Vitro-vivo correlations and cross-resistance to other drugs
-
Kaspers, G.J.; Pieters, R.; van Zantwijk, C.H.; VanWering, E.R.; van der Does-Van Den Berg, A.; Veerman, A.J. Prednisolone resistance in childhood acute lymphoblastic leukemia: Vitro-vivo correlations and cross-resistance to other drugs. Blood 1998, 92, 259-266.
-
(1998)
Blood
, vol.92
, pp. 259-266
-
-
Kaspers, G.J.1
Pieters, R.2
Van Zantwijk, C.H.3
VanWering, E.R.4
Van Der Does-Van Den Berg, A.5
Veerman, A.J.6
-
49
-
-
77950516941
-
Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA
-
Ding, J.; Huang, S.L.; Wu, S.Q.; Zhao, Y.J.; Liang, L.H.; Yan, M.X.; Ge, C.; Yao, J.; Chen, T.Y.; Wan, D.F.; et al. Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA. Nat. Cell Biol. 2010, 12, 390-399.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 390-399
-
-
Ding, J.1
Huang, S.L.2
Wu, S.Q.3
Zhao, Y.J.4
Liang, L.H.5
Yan, M.X.6
Ge, C.7
Yao, J.8
Chen, T.Y.9
Wan, D.F.10
|