Application of high-resolution MS in the quantification of a therapeutic monoclonal antibody in human plasma

Bioanalysis

Volumn 6, Issue 13, 2014, Pages 1767-1779

  Mekhssian, Kevork ^a   Mess, Jean Nicholas ^a   Garofolo, Fabio ^a  

^a Algorithme Pharma Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; RITUXIMAB; SYNTHETIC PEPTIDE; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; PEPTIDE; TRYPSIN;

ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; HEAVY CHAIN; HUMAN; LIGHT CHAIN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEASUREMENT ACCURACY; PEPTIDE MAPPING; PROCESS OPTIMIZATION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; AMINO ACID SEQUENCE; BLOOD; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDE MAPPING; PEPTIDES; TRYPSIN;

EID: 84906660597     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.14.111     Document Type: Article

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