Sequential protein and peptide immunoaffinity capture for mass spectrometry-based quantification of total human β-nerve growth factor

Analytical Chemistry

Volumn 85, Issue 3, 2013, Pages 1719-1726

  Neubert, Hendrik ^a   Muirhead, David ^b   Kabir, Musarat ^b   Grace, Chris ^b,c   Cleton, Adriaan ^b,d   Arends, Rosalin ^a  

^a PFIZER INC   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOANALYTICAL PLATFORMS; CHRONIC PAIN; CLINICAL ANALYSIS; CLINICAL STUDY; CLINICAL TRIAL; DOSE-DEPENDENT MANNER; HUMAN SERUM; HUMANIZED MONOCLONAL ANTIBODY; IMMUNOAFFINITY; INTER-ASSAY COEFFICIENTS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY ASSAYS; NANOFLOWS; NERVE GROWTH FACTOR; NEUROTROPHINS; PAIN PERCEPTION; POLYCLONAL ANTIBODY; PROTEIN TARGETS; QUANTITATIVE DETERMINATIONS; RELATIVE ERRORS; SAMPLE PREPARATION; TRYPTIC PEPTIDES;

ANTIGEN-ANTIBODY REACTIONS; BODY FLUIDS; DRUG PRODUCTS; ENZYME INHIBITION; EXPERIMENTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICAL APPLICATIONS; PEPTIDES;

ASSAYS;

NERVE GROWTH FACTOR; NGF PROTEIN, HUMAN; PEPTIDE FRAGMENT;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; DOG; GENETICS; HUMAN; IMMUNOASSAY; LIQUID CHROMATOGRAPHY; MACACA FASCICULARIS; MASS SPECTROMETRY; METHODOLOGY; MOLECULAR GENETICS; RAT; TANDEM MASS SPECTROMETRY;

AMINO ACID SEQUENCE; ANIMALS; CHROMATOGRAPHY, LIQUID; DOGS; HUMANS; IMMUNOASSAY; MACACA FASCICULARIS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; NERVE GROWTH FACTOR; PEPTIDE FRAGMENTS; RATS; TANDEM MASS SPECTROMETRY;

EID: 84873385425     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac303031q     Document Type: Article

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