Pellet digestion: A simple and efficient sample preparation technique for LC-MS/MS quantification of large therapeutic proteins in plasma

Bioanalysis

Volumn 4, Issue 1, 2012, Pages 17-28

  Ouyang, Zheng ^a   Furlong, Michael T ^a   Wu, Steven ^a   Sleczka, Bogdan ^a   Tamura, James ^a   Wang, Haiqing ^a   Suchard, Suzanne ^a   Suri, Anish ^a   Olah, Timothy ^a   Tymiak, Adrienne ^a   Jemal, Mohammed ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHANOL; ORGANIC SOLVENT; PHOSPHOLIPID; SYNAPSIN I;

ACCURACY; ARTICLE; CHEMICAL PROCEDURES; CONTROLLED STUDY; HAPLORHINI; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; NONHUMAN; PELLET DIGESTION; PHOSPHOLIPID BLOOD LEVEL; PHOSPHOLIPID METABOLISM; PLASMA CONCENTRATION-TIME CURVE; PRECIPITATION; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN DENATURATION; PROTEIN ISOLATION; PROTEIN TARGETING; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

BLOOD PROTEINS; CHROMATOGRAPHY, LIQUID; PROTEOLYSIS; SPECIMEN HANDLING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84555218349     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.11.286     Document Type: Article

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