Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis

Journal of the American Society of Nephrology

Volumn 25, Issue 5, 2014, Pages 905-912

  Tampe, Björn ^a   Tampe, Desiree ^a   Müller, Claudia A ^a,b   Sugimoto, Hikaru ^c   LeBleu, Valerie ^c   Xu, Xingbo ^a,d   Müller, Gerhard A ^a   Zeisberg, Elisabeth M ^a,d   Kalluri, Raghu ^c   Zeisberg, Michael ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; MESSENGER RNA; OSTEOGENIC PROTEIN 1; PROTEIN; RASAL1 PROTEIN; TET3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; BMP7 PROTEIN, MOUSE; DNA BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; ONCOPROTEIN; RASAL1 PROTEIN, MOUSE; TET3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFIBROTIC ACTIVITY; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DRUG ACTIVITY; EPIGENETICS; GEL MOBILITY SHIFT ASSAY; GENE SILENCING; HYDROXYMETHYLATION; KIDNEY FIBROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; ANIMAL; CELL CULTURE; DRUG EFFECT; GENETIC EPIGENESIS; GENETICS; METABOLISM; NEPHROSCLEROSIS; PHYSIOLOGY; URETER OBSTRUCTION;

ANIMALS; BIOLOGICAL MARKERS; BONE MORPHOGENETIC PROTEIN 7; CELLS, CULTURED; DNA METHYLATION; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; GENE SILENCING; GTPASE-ACTIVATING PROTEINS; MICE; NEPHROSCLEROSIS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; URETERAL OBSTRUCTION;

EID: 84906547871     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2013070723     Document Type: Article

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