Anesthetic cardioprotection in relation to mitochondria: Basic science

Current Pharmaceutical Design

Volumn 20, Issue 36, 2014, Pages 5673-5680

  Mio, Yasushi ^a   Uezono, Shoichi ^a   Kitahata, Hiroshi ^b  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Anesthetics; Cardioprotection; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ANESTHETIC AGENT; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; CARRIER PROTEIN; REACTIVE OXYGEN METABOLITE;

ACIDIFICATION; ANESTHETIC POSTCONDITIONING; ANESTHETIC PRECONDITIONING; ARTICLE; HEART MITOCHONDRION; HEART PROTECTION; HUMAN; INTRACELLULAR SIGNALING; ISCHEMIC POSTCONDITIONING; ISCHEMIC PRECONDITIONING; MITOCHONDRIAL MEMBRANE; NONHUMAN; PH; PRIORITY JOURNAL; REPERFUSION INJURY; ANIMAL; DRUG EFFECTS; HEART INFARCTION PREVENTION; HEART MUSCLE CELL; METABOLISM; MYOCARDIAL REPERFUSION INJURY; PATHOPHYSIOLOGY; PROCEDURES;

ADENOSINE TRIPHOSPHATE; ANESTHETICS; ANIMALS; HUMANS; HYDROGEN-ION CONCENTRATION; ISCHEMIC POSTCONDITIONING; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; REACTIVE OXYGEN SPECIES;

EID: 84906504167     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612820666140204110101     Document Type: Article

References (77)

1. ATP channels: reduction of myocardial infarct size with an acute memory phase. Anesthesiology 1997; 87: 361-70.
2. Schlack W, Preckel B, Barthel H, Obal D, Thämer V. Halothane reduces reperfusion injury after regional ischaemia in the rabbit heart in vivo. Br J Anaesth 1997; 79: 88-96.
3. Chiari PC, Bienengraeber MW, Pagel PS, Krolikowski JG, Kersten JR, Warltier DC. Isoflurane protects against myocardial infarction during early reperfusion by activation of phosphatidylinositol-3-kinase signal transduction: evidence for anesthetic-induced postconditioning in rabbits. Anesthesiology 2005; 102: 102-9.
4. Fleisher LA, Beckman JA, Brown KA, et al. 2009 ACCF/AHA focused update on perioperative beta blockade incorporated into the ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery. J Am Coll Cardiol 2009; 54: e13-118.
5. Chen H, Chan DC. Physiological functions of mitochondrial fusion. Ann N Y Acad Sci, 2010; 1201: 21-5.
6. Heath-Engel HM, Shore GC. Mitochondrial membrane dynamics, cristae remodelling and apoptosis. Biochim Biophys Acta, 2006; 1763: 549-60.
7. Tanaka K, Weihrauch D, Kehl F, et al. Mechanism of preconditioning by isoflurane in rabbits: a direct role for reactive oxygen species. Anesthesiology 2002; 97: 1485-90.
8. Kevin LG, Novalija E, Riess ML, Camara AK, Rhodes SS, Stowe DF. Sevoflurane exposure generates superoxide but leads to decreased superoxide during ischemia and reperfusion in isolated hearts. Anesth Analg 2003; 96: 949-55.
9. Ambrosio G, Zweier JL, Duilio C, et al. Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow. J Biol Chem, 1993; 268: 18532-41.
10. Gottlieb RA, Burleson KO, Kloner RA, Babior BM, Engler RL. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest. 1994; 94: 1621-8.
11. Lesnefsky EJ, Chen Q, Moghaddas S, Hassan MO, Tandler B, Hoppel CL. Blockade of electron transport during ischemia protects cardiac mitochondria. J Biol Chem, 2004; 279: 47961-7.
12. Hirata N, Shim YH, Pravdic D, et. al. Isoflurane differentially modulates mitochondrial reactive oxygen species production via forward versus reverse electron transport flow: implications for preconditioning. Anesthesiology 2011; 115: 531-40.
13. Pravdic D, Mio Y, Sedlic F, et al. Isoflurane protects cardiomyocytes and mitochondria by immediate and cytosol-independent action at reperfusion. Br J Pharmacol 2010; 160: 220-32.
14. Halestrap AP, McStay GP, Clarke SJ. The permeability transition pore complex: another view. Biochimie 2002; 84: 153-66.
15. Dlasková A, Hlavatá L, Jezek J, Jezek P. Mitochondrial Complex I superoxide production is attenuated by uncoupling. Int J Biochem Cell Biol 2008; 40: 2098-109.
16. Pravdic D, Hirata N, Barber L, Sedlic F, Bosnjak ZJ, Bienengraeber M. Complex I and ATP synthase mediate membrane depolarization and matrix acidification by isoflurane in mitochondria. Eur J Pharmacol 2012; 690: 149-57.
17. Bienengraeber MW, Weihrauch D, Kersten JR, Pagel PS, Warltier DC. Cardioprotection by volatile anesthetics. Vascul Pharmacol 42: 243-52. 2005.
18. Stadnicka A, Marinovic J, Ljubkovic M, Bienengraeber MW, Bosnjak ZJ. Volatile anesthetic-induced cardiac preconditioning. J Anesth 2007; 21: 212-9.
19. Mio Y, Shim YH, Richards E, Bosnjak ZJ, Pagel PS, Bienengraeber M. Xenon preconditioning: the role of prosurvival signaling, mitochondrial permeability transition and bioenergetics in rats. Anesth Analg 2008; 108: 858-66.
20. Chiari PC, Bienengraeber MW, Weihrauch D, et al. Role of endothelial nitric oxide synthase as a trigger and mediator of isofluraneinduced delayed preconditioning in rabbit myocardium. Anesthesiology 2005; 103: 74-83.
21. Novalija E, Kevin LG, Camara AK, Bosnjak ZJ, Kampine JP, Stowe DF. Reactive oxygen species precede the epsilon isoform of protein kinase C in the anesthetic preconditioning signaling cascade. Anesthesiology 2003; 99: 421-8.
22. Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem J. 1999; 341: 233-49.
23. Di Lisa F, Bernardi P. A CaPful of mechanisms regulating the mitochondrial permeability transition. J Mol Cell Cardiol, 2009; 46: 775-80.
24. 2+ overloading, trigger pH-and mitochondrial permeability transitiondependent death of adult rat myocytes after ischemia-reperfusion. Am J Physiol Heart Circ Physiol, 2006; 290: H2024-34.
25. Argaud L, Gateau-Roesch O, Muntean D, et al. Specific inhibition of the mitochondrial permeability transition prevents lethal reperfusion injury. J Mol Cell Cardiol, 2005; 38: 367-74.
26. Juhaszova M, Zorov DB, Kim SH, et al. Glycogen synthase kinase-3 mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore. J Clin Invest 2004; 113: 1535-49.
27. Rakhit RD, Mojet MH, Marber MS, Duchen MR. Mitochondria as targets for nitric oxide-induced protection during simulated ischemia and reoxygenation in isolated neonatal cardiomyocytes. Circulation 2001; 103: 2617-23.
28. Oka N, Wang L, Mi W, Zhu W, Honjo O, Caldarone CA. Cyclosporine A prevents apoptosis-related mitochondrial dysfunction after neonatal cardioplegic arrest. J Thorac Cardiovasc Surg, 2008; 135: 123-30, 130 e1-2.
29. Halestrap AP. The mitochondrial permeability transition: its molecular mechanism and role in reperfusion injury. Biochem Soc Symp, 1999; 66: 181-203.
30. Baines CP, Kaiser RA, Sheiko T, Craigen WJ, Molkentin JD. Voltage-dependent anion channels are dispensable for mitochondrialdependent cell death. Nat Cell Biol, 2007; 9: 550-5.
31. Kokoszka JE, Waymire KG, Levy SE, et al. The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature, 2004; 427: 461-5.
32. Baines CP, Kaiser RA, Purcell NH, et al. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature, 2005; 434: 658-62.
33. Pagel PS. Postconditioning by volatile anesthetics: salvaging ischemic myocardium at reperfusion by activation of prosurvival signaling. J Cardiothorac Vasc Anesth 2008; 22: 753-65.
34. Ge ZD, Pravdic D, Bienengraeber M, et al. Isoflurane postconditioning protects against reperfusion injury by preventing mitochondrial permeability transition by an endothelial nitric oxide synthasedependent mechanism. Anesthesiology 2010; 112: 73-85.
35. + channel in the mitochondrial inner membrane. Nature, 1991; 352: 244-7.
36. Liu Y, Sato T, O'Rourke B, Marban E. Mitochondrial ATPdependent potassium channels: novel effectors of cardioprotection? Circulation, 1998; 97: 2463-9.
37. + channel from rat liver and beef heart mitochondria. J Biol Chem, 1992; 267: 26062-9.
38. Rusznak Z, Bakondi G, Kosztka L, et al. Mitochondrial expression of the two-pore domain TASK-3 channels in malignantly transformed and non-malignant human cells. Virchows Arch, 2008; 452: 415-26.
39. 2+-activated K channel of the BK-type in the inner mitochondrial membrane of a human glioma cell line. Biochem Biophys Res Commun, 1999; 257: 549-54.
40. Szabo I, Bock J, Jekle A, et al. A novel potassium channel in lymphocyte mitochondria. J Biol Chem, 2005; 280: 12790-8.
41. + channels in cardiac myocytes: a mechanism of the cardioprotective effect and modulation by protein kinase A. Circulation, 2005; 111: 198-203.
42. Seino S. ATP-sensitive potassium channels: a model of heteromultimeric potassium channel/receptor assemblies. Annu Rev Physiol, 1999; 61: 337-62.
43. Singh H, Hudman D, Lawrence CL, Rainbow RD, Lodwick D, Norman RI. Distribution of Kir6. 0 and SUR2 ATP-sensitive potassium channel subunits in isolated ventricular myocytes. J Mol Cell Cardiol, 2003; 35: 445-59.
44. + channels in mitochondria. Biochem Biophys Res Commun, 1997; 241: 693-7.
45. Szewczyk A, Wójcik G, Lobanov NA, Nałecz MJ. The mitochondrial sulfonylurea receptor: identification and characterization. Biochem Biophys Res Commun, 1997; 230: 611-5.
46. ATP? Biochem Biophys Res Commun 2008; 366: 649-656.
47. Seharaseyon J, Ohler A, Sasaki N, et al. Molecular composition of mitochondrial ATP-sensitive potassium channels probed by viral Kir gene transfer. J Mol Cell Cardiol 2000; 32: 1923-30.
48. Tanaka K, Weihrauch D, Ludwig LM, Kersten JR, Pagel PS, Warltier DC. Mitochondrial adenosine triphosphate-regulated potassium channel opening acts as a trigger for isoflurane-induced preconditioning by generating reactive oxygen species. Anesthesiology 2003; 98: 935-43.
49. ATP increases superoxide generation from complex I of the electron transport chain. Am J Physiol Heart Circ Physiol, 2006; 291: H2067-74.
50. Costa AD, Pierre SV, Cohen MV, Downey JM, Garlid KD. cGMP signalling in pre-and post-conditioning: the role of mitochondria. Cardiovasc Res, 2008; 77: 344-52.
51. Novalija E, Kevin LG, Eells JT, Henry MM, Stowe DF. Anesthetic preconditioning improves adenosine triphosphate synthesis and reduces reactive oxygen species formation in mitochondria after ischemia by a redox dependent mechanism. Anesthesiology, 2003; 98: 1155-63.
52. + channels reconstituted in lipid bilayers. Am J Physiol Heart Circ Physiol 2003; 284: H1865-71.
53. Gunter TE, Pfeiffer DR. Mechanisms by which mitochondria transport calcium. Am J Physiol, 1990; 258: C755-86.
54. ATP opening on heart mitochondria. Am J Physiol Heart Circ Physiol, 2006; 290: H406-15.
55. + transport. Am J Physiol Heart Circ Physiol, 2003; 285: H154-62.
56. + channel of heart mitochondria. Am J Physiol Heart Circ Physiol, 2001; 280: H649-57.
57. Halestrap AP. Regulation of mitochondrial metabolism through changes in matrix volume. Biochem Soc Trans 1994; 22: 522-9.
58. ATP channels in cell survival and death. J Mol Cell Cardiol. 2005; 39: 7-16.
59. ATP channels in mitochondrial cytoprotective signaling. J Biol Chem, 2006; 281: 23733-9.
60. ATP channelindependent targets of diazoxide and 5-hydroxydecanoate in the heart. J Physiol, 2002; 542: 735-41.
61. Ca channel by cGMP and cAMP kinase. J Biol Chem, 2001; 276: 43239-45.
62. + channels in the cardiac inner mitochondrial membrane. Science, 2002; 298: 1029-33.
63. + channels via protein kinase A mediates desflurane-induced preconditioning. Anesth Analg, 2008; 106: 384-91.
64. Ljubkovic M, Mio Y, Marinovic J, et al. Isoflurane preconditioning uncouples mitochondria and protects against hypoxiareoxygenation. Am J Physiol Cell Physiol. 2007; 292: C1583-90.
65. 2+ uniporter by external adenine nucleotides: the uniporter behaves like a gated channel which is regulated by nucleotides and divalent cations. Biochemistry, 1997; 36: 7071-80.
66. Baughman JM, Perocchi F, Girgis HS, et al. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 2011; 476: 341-5.
67. De Stefani D, Raffaello A, Teardo E, Szabò I, Rizzuto R. A fortykilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 2011; 476: 336-40.
68. 2+ network. J Cell Biol 1997; 136: 833-44.
69. + exchanger. J Cell Biol 1998; 273: 6951-9.
70. 2+ transport. J Bioenerg Biomembr 1994; 26: 495-508.
71. 2+ and attenuated ADP-induced NADH oxidation by isoflurane: Implications for cardioprotection. Biochim Biophys Acta. 2012; 1817: 453-65.
72. 2+ overload during ischemia in Guinea pig intact hearts: reversal by 5-hydroxydecanoic acid. Anesth Analg. 2002; 95: 1540-6.
73. Sepac A, Sedlic F, Si-Tayeb K, et al. Isoflurane preconditioning elicits competent endogenous mechanisms of protection from oxidative stress in cardiomyocytes derived from human embryonic stem cells. Anesthesiology 2010; 113: 906-16.
74. 2+ loading and improved functional recovery after ischemia-reperfusion injury in old vs. young guinea pig hearts. Am J Physiol Heart Circ Physiol 2012; 302: H855-63.
75. Raphael J, Gozal Y, Navot N, Zuo Z. Hyperglycemia inhibits anesthetic-induced postconditioning in the rabbit heart via modulation of phosphatidylinositol-3-kinase/Akt and endothelial nitric oxide synthase signaling. J Cardiovasc Pharmacol 2010; 55: 348-57.
76. Mio Y, Bienengraeber MW, Marinovic J, et al. Age-related attenuation of isoflurane preconditioning in human atrial cardiomyocytes: roles for mitochondrial respiration and sarcolemmal adenosine triphosphate-sensitive potassium channel activity. Anesthesiology 2008; 108: 612-20.
77. Amour J, Brzezinska AK, Jager Z, et al. Hyperglycemia adversely modulates endothelial nitric oxide synthase during anesthetic preconditioning through tetrahydrobiopterin-and heat shock protein 90-mediated mechanisms. Anesthesiology 2010; 112: 576-85.