Reduced mitochondrial Ca 2+ loading and improved functional recovery after ischemia-reperfusion injury in old vs. young guinea pig hearts

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 3, 2012, Pages

  Rhodes, Samhita S ^a,b   Camara, Amadou K S ^b   Heisner, James S ^b   Riess, Matthias L ^b,c   Aldakkak, Mohammed ^b   Stowe, David F ^b,c  

^a GRAND VALLEY STATE UNIVERSITY   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Aging; Cardiac calcium handling; Guinea pigs; Ischemia reperfusion injury

Indexed keywords

CALCIUM ION; DIGOXIN; DOPAMINE; CALCIUM; CARDIOTONIC AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CONDUCTANCE; CITRIC ACID CYCLE; CONTROLLED STUDY; EXPERIMENTAL GUINEA PIG; FUNCTIONAL STATUS; HEART INFARCTION SIZE; HEART LEFT VENTRICLE PRESSURE; HEART MITOCHONDRION; HEART MUSCLE ISCHEMIA; HEART RATE; HEART VENTRICLE WALL; INOTROPISM; ISCHEMIA REPERFUSION INJURY; ISOLATED HEART; NONHUMAN; OUTCOME ASSESSMENT; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; REPERFUSION INJURY; TISSUE PERFUSION; AGING; ANIMAL; COMPARATIVE STUDY; CONVALESCENCE; CORONARY ARTERY BLOOD FLOW; CYTOSOL; DRUG EFFECT; GUINEA PIG; HEART CONTRACTION; HEART INFARCTION; HEART MUSCLE; METABOLISM; MITOCHONDRION; PHYSIOLOGY;

AGING; ANIMALS; CALCIUM; CARDIOTONIC AGENTS; CORONARY CIRCULATION; CYTOSOL; DIGOXIN; DOPAMINE; GUINEA PIGS; MITOCHONDRIA; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NAD; RECOVERY OF FUNCTION;

EID: 84856446031     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00533.2011     Document Type: Article

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