Molecular composition of mitochondrial ATP-sensitive potassium channels probed by viral kit gene transfer

Journal of Molecular and Cellular Cardiology

Volumn 32, Issue 11, 2000, Pages 1923-1930

  Seharaseyon, Jegatheesan ^a   Ohler, Andreas ^a   Sasaki, Norihito ^a   Fraser, Heather ^a   Sato, Toshiaki ^a   Johns, David C ^a   O'Rourke, Brian ^a   Marbán, Eduardo ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenoviral gene transfer; Flavoprotein fluorescence; Mitochondrial mitoK(ATP) channel (mitoK(ATP)); Potassium inward rectifier (Kir)

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE; ADENOSINE TRIPHOSPHATE; DIAZOXIDE; MITOCHONDRION ANTIBODY; MITOCHONDRION ANTIBODY KIRB 1; SULFONYLUREA RECEPTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS PROTEIN KIR;

ARTICLE; CHEMICAL COMPOSITION; GENE TRANSFER; HEART MUSCLE CELL; HEART VENTRICLE WALL; IMMUNOHISTOCHEMISTRY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; RABBIT;

EID: 0033739636     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1226     Document Type: Article

References (30)

1. + channels in cardiac muscle
2. Inward-rectifying channels in isolated patches of the heart cell membranes ATP-dependence and comparison with cell-attached patch
3. + channels in the TE671 human medulloblastoma cell line
4. Cloning of the beta cell high-affinity sulfonylurea receptor: A regulator of insulin secretion
5. + channel in the mitochondrial inner membrane
6. + channels from rat liver and beef heart mitochondria
7. Potassium channel opener, RP66471, induces membrane depolarization of rat liver mitochondria
8. + channels. Possible mechanism of cardioprotection
9. Mitochondrial ATP-dependent potassium channels: Novel effectors of cardioprotection?
10. + channels by protein kinase C
11. + channels
12. Suppression of KATP currents by gene transfer of a dominant negative Kir6.2 construct
13. Reconstituted human cardiac KATP channels: Functional identity with the native channels from the sarcolemma of human ventricular cells
14. + channel subunits confer resistance to chemical hypoxiareoxygenation injury
15. Pharmacological and histochemical distinctions between molecularly defined sarcolemmal KATP channels and native cardiac mitochondrial KATP channels
16. Abnormalities of pancreatic islets by targeted expression of a dominant-negative KATP channel
17. Cloning and functional characterization of a novel ATPsensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle and heart
18. Myocardial ischemia induces differential regulation of KATP channel gene expression in rat hearts
19. + channels in mitochondria
20. Evidence against functional heteromultimerization of the KATP channel subunits Kir6.1 and Kir6.2
21. Regions responsible for the assembly of inwardly rectifying potassium channels
22. Suppression of neuronal and cardiac transient outward currents by viral gene transfer of dominant-negative K4.2 constructs
23. Functional knockout of the transient outward current, long-QT syndrome and cardiac remodeling in mice expressing a dominant-negative KV4 alpha subunit
24. Inducible genetic suppression of reuronal excitability
25. Construction of adenovirus vectors through cre-lox recombination
26. Cell-type specificity of preconditioning in an in vitro model
27. Subcellular metabolic transients and mitochondrial redox waves in heart cells
28. + channel in rabbit ventricular myocytes
29. + channel
30. Regulatory sites of mito KATP are on mito SUR