Gabapentin enhances the morphine anti-nociceptive effect in neuropathic pain via the interleukin-10-heme oxygenase-1 signalling pathway in rats

Journal of Molecular Neuroscience

Volumn 54, Issue 1, 2014, Pages 137-146

  Bao, Yu Hua ^a   Zhou, Quan Hong ^a   Chen, Rui ^a   Xu, Hao ^a   Zeng, Lu Lu ^a   Zhang, Xin ^a   Jiang, Wei ^a   Du, Dong Ping ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Gabapentin; Heme oxygenase (HO) 1; Inflammatory cytokine; Interleukin(IL) 10; Morphine tolerance; Neuropathic pain

Indexed keywords

GABAPENTIN; HEME OXYGENASE 1; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 10 ANTIBODY; INTERLEUKIN 1BETA; INTERLEUKIN 6; MORPHINE; PROTOPORPHYRIN ZINC; RECOMBINANT INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA; 4 AMINOBUTYRIC ACID; AMINE; ANALGESIC AGENT; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; PROTOPORPHYRIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; MALE; NEUROPATHIC PAIN; NONHUMAN; RAT; SIGNAL TRANSDUCTION; TAIL FLICK TEST; VON FREY TEST; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENETICS; METABOLISM; NEURALGIA; NOCICEPTION; SPRAGUE DAWLEY RAT;

RATTUS;

AMINES; ANALGESICS; ANIMALS; CYCLOHEXANECARBOXYLIC ACIDS; GAMMA-AMINOBUTYRIC ACID; HEME OXYGENASE-1; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; MORPHINE; NEURALGIA; NOCICEPTION; PROTOPORPHYRINS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84906333522     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0262-2     Document Type: Article

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