Mechanisms of esophageal protection, gastroprotection and ulcer healing by mela-tonin. Implications for the therapeutic use of melatonin in gastroesophageal reflux disease (gerd) and peptic ulcer disease

Current Pharmaceutical Design

Volumn 20, Issue 30, 2014, Pages 4807-4815

  Brzozowska, Iwona ^a   Strzalka, Malgorzata ^a   Drozdowicz, Danuta ^b   Konturek, Stanislaw J ^a   Brzozowski, Tomasz ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b Department of Physiology Jagiellonian University College of Medicine ^*

Author keywords

Active oxygen metabolites; Brain gut axis; Gastric blood flow; Gastroprotection; L tryptophan; Melatonin; Nitric oxide; Prostaglandins; Sensory nerves; Ulcer healing

Indexed keywords

GASTRIN; MATRIX METALLOPROTEINASE; MELATONIN; MELATONIN RECEPTOR; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; TRYPTOPHAN; GELATINASE B; INDOLEAMINE; PROSTAGLANDIN SYNTHASE INHIBITOR; STROMELYSIN;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; CELL ORGANELLE; CELL PROLIFERATION; COLON MOTILITY; DRUG MECHANISM; ESOPHAGEAL PROTECTION; ESOPHAGUS INJURY; GASTRIN BLOOD LEVEL; GASTROENTEROLOGICAL PROCEDURE; GASTROESOPHAGEAL REFLUX; GASTROPROTECTION; HUMAN; NONHUMAN; OXIDATIVE STRESS; PEPTIC ULCER; PINEAL BODY; PRIORITY JOURNAL; PROPHYLAXIS; PROTECTION; REFLUX ESOPHAGITIS; REVIEW; STOMACH BLOOD FLOW; STOMACH MUCOSA; ULCER HEALING; ARTICLE; DRUG EFFECT; DRUG USE; PINEALECTOMY; STOMACH LESION; STOMACH PROTECTION; THERAPY EFFECT; DRUG EFFECTS; ESOPHAGUS;

ESOPHAGUS; GASTROESOPHAGEAL REFLUX; HUMANS; MELATONIN; PEPTIC ULCER;

EID: 84906271889     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612819666131119110258     Document Type: Review

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