Synthesis of a FTO inhibitor with anticonvulsant activity

ACS Chemical Neuroscience

Volumn 5, Issue 8, 2014, Pages 658-665

  Zheng, Guanqun ^a   Cox, Thomas ^b   Tribbey, Leah ^b   Wang, Gloria Z ^a   Iacoban, Paulina ^b   Booher, Matthew E ^d   Gabriel, Gregory J ^d   Zhou, Lu ^e   Bae, Nancy ^c   Rowles, Joie ^b   He, Chuan ^a   Olsen, Mark J ^b  

^a UNIVERSITY OF CHICAGO   (United States)

^b MIDWESTERN UNIVERSITY   (United States)

^c MIDWESTERN UNIVERSITY   (United States)

^d KENNESAW STATE UNIVERSITY   (United States)

^e FUDAN UNIVERSITY   (China)

Author keywords

Anticonvulsant; epilepsy; FTO; microRNA; RNA

Indexed keywords

6 N METHYLADENOSINE; ASCORBIC ACID; ETIRACETAM; MICRORNA; OXYGENASE; SULFONAMIDE; ADENOSINE; ANTICONVULSIVE AGENT; FTO PROTEIN, HUMAN; FTO PROTEIN, MOUSE; LYASE; MIXED FUNCTION OXIDASE; N(6)-METHYLADENOSINE; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG PENETRATION; DRUG SAFETY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; ROTAROD TEST; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; DISEASE MODEL; ENZYME ACTIVE SITE; EPILEPSY; HELA CELL LINE; METABOLISM; SYNTHESIS; WESTERN BLOTTING;

ADENOSINE; ANIMALS; ANTICONVULSANTS; BLOTTING, WESTERN; CATALYTIC DOMAIN; DISEASE MODELS, ANIMAL; EPILEPSY; HELA CELLS; HUMANS; MICE; MICRORNAS; MIXED FUNCTION OXYGENASES; MODELS, CHEMICAL; MOLECULAR STRUCTURE; OXO-ACID-LYASES; PROTEINS;

EID: 84906243835     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn500042t     Document Type: Article

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