메뉴 건너뛰기




Volumn 53, Issue 9, 2014, Pages 753-763

Differential effects on lung cancer cell proliferation by agonists of glucocorticoid and PPARα receptors

Author keywords

Budesonide; Fenofibrate; Glucocorticoid receptor (GR); Lung cancer; Peroxisome proliferator activated receptor (PPAR )

Indexed keywords

BUDESONIDE; CYCLINE; FENOFIBRATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN P53; ANTIINFLAMMATORY AGENT; ANTILIPEMIC AGENT; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; TP53 PROTEIN, HUMAN;

EID: 84906097404     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22029     Document Type: Article
Times cited : (33)

References (71)
  • 2
    • 47749150261 scopus 로고    scopus 로고
    • Cancer and inflammation: A complex relationship
    • Mantovani A, Pierotti MA. Cancer and inflammation: A complex relationship. Cancer Lett 2008; 267:180-181.
    • (2008) Cancer Lett , vol.267 , pp. 180-181
    • Mantovani, A.1    Pierotti, M.A.2
  • 3
    • 74049140048 scopus 로고    scopus 로고
    • Inflammation and cancer: Interweaving microRNA, free radical, cytokine and p53 pathways
    • Schetter AJ, Heegaard NH, Harris CC. Inflammation and cancer: Interweaving microRNA, free radical, cytokine and p53 pathways. Carcinogenesis 2010; 31:37-49.
    • (2010) Carcinogenesis , vol.31 , pp. 37-49
    • Schetter, A.J.1    Heegaard, N.H.2    Harris, C.C.3
  • 4
    • 0031474156 scopus 로고    scopus 로고
    • Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo
    • Vayssiere BM, Dupont S, Choquart A, et al. Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo. Mol Endocrinol 1997; 11:1245-1255.
    • (1997) Mol Endocrinol , vol.11 , pp. 1245-1255
    • Vayssiere, B.M.1    Dupont, S.2    Choquart, A.3
  • 5
    • 34548249241 scopus 로고    scopus 로고
    • Effects of glucocorticoids on apoptosis and clearance of apoptotic cells
    • McColl A, Michlewska S, Dransfield I, Rossi AG. Effects of glucocorticoids on apoptosis and clearance of apoptotic cells. Sci World J 2007; 7:1165-1181.
    • (2007) Sci World J , vol.7 , pp. 1165-1181
    • McColl, A.1    Michlewska, S.2    Dransfield, I.3    Rossi, A.G.4
  • 6
    • 0026685139 scopus 로고
    • Implication of glucocorticoid receptors in the stimulation of human glioma cell proliferation by dexamethasone
    • Langeveld CH, van Waas MP, Stoof JC, et al. Implication of glucocorticoid receptors in the stimulation of human glioma cell proliferation by dexamethasone. J Neurosci Res 1992; 31:524-531.
    • (1992) J Neurosci Res , vol.31 , pp. 524-531
    • Langeveld, C.H.1    van Waas, M.P.2    Stoof, J.C.3
  • 7
    • 0031034054 scopus 로고    scopus 로고
    • Glucocorticoids induce Kaposi's sarcoma cell proliferation through the regulation of transforming growth factor-beta
    • Cai J, Zheng T, Lotz M, Zhang Y, Masood R, Gill P. Glucocorticoids induce Kaposi's sarcoma cell proliferation through the regulation of transforming growth factor-beta. Blood 1997; 89:1491-1500.
    • (1997) Blood , vol.89 , pp. 1491-1500
    • Cai, J.1    Zheng, T.2    Lotz, M.3    Zhang, Y.4    Masood, R.5    Gill, P.6
  • 8
    • 0036729435 scopus 로고    scopus 로고
    • Glucocorticoids inhibit lung cancer cell growth through both the extracellular signal-related kinase pathway and cell cycle regulators
    • Greenberg AK, Hu J, Basu S, et al. Glucocorticoids inhibit lung cancer cell growth through both the extracellular signal-related kinase pathway and cell cycle regulators. Am J Respir Cell Mol Biol 2002; 27:320-328.
    • (2002) Am J Respir Cell Mol Biol , vol.27 , pp. 320-328
    • Greenberg, A.K.1    Hu, J.2    Basu, S.3
  • 10
    • 77951901129 scopus 로고    scopus 로고
    • Structural overview of the nuclear receptor superfamily: Insights into physiology and therapeutics
    • Huang P, Chandra V, Rastinejad F. Structural overview of the nuclear receptor superfamily: Insights into physiology and therapeutics. Annu Rev Physiol 2010; 72:247-272.
    • (2010) Annu Rev Physiol , vol.72 , pp. 247-272
    • Huang, P.1    Chandra, V.2    Rastinejad, F.3
  • 11
    • 33646772536 scopus 로고    scopus 로고
    • The nuclear receptor superfamily and drug discovery
    • Moore JT, Collins JL, Pearce KH. The nuclear receptor superfamily and drug discovery. ChemMedChem 2006; 1:504-523.
    • (2006) ChemMedChem , vol.1 , pp. 504-523
    • Moore, J.T.1    Collins, J.L.2    Pearce, K.H.3
  • 12
    • 33751533892 scopus 로고    scopus 로고
    • International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors
    • Michalik L, Auwerx J, Berger JP, et al. International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors. Pharmacol Rev 2006; 58:726-741.
    • (2006) Pharmacol Rev , vol.58 , pp. 726-741
    • Michalik, L.1    Auwerx, J.2    Berger, J.P.3
  • 13
    • 78650317248 scopus 로고    scopus 로고
    • Endogenous ligands for nuclear receptors: Digging deeper
    • Schupp M, Lazar MA. Endogenous ligands for nuclear receptors: Digging deeper. J Biol Chem 2010; 285:40409-40415.
    • (2010) J Biol Chem , vol.285 , pp. 40409-40415
    • Schupp, M.1    Lazar, M.A.2
  • 14
    • 0030747895 scopus 로고    scopus 로고
    • Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: No alteration in adipose tissue of obese and NIDDM patients
    • Auboeuf D, Rieusset J, Fajas L, et al. Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: No alteration in adipose tissue of obese and NIDDM patients. Diabetes 1997; 46:1319-1327.
    • (1997) Diabetes , vol.46 , pp. 1319-1327
    • Auboeuf, D.1    Rieusset, J.2    Fajas, L.3
  • 15
    • 1542283630 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha target genes
    • Mandard S, Muller M, Kersten S. Peroxisome proliferator-activated receptor alpha target genes. Cell Mol Life Sci 2004; 61:393-416.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 393-416
    • Mandard, S.1    Muller, M.2    Kersten, S.3
  • 16
    • 34447618831 scopus 로고    scopus 로고
    • PPARs and their metabolic modulation: New mechanisms for transcriptional regulation
    • Ahmed W, Ziouzenkova O, Brown J, et al. PPARs and their metabolic modulation: New mechanisms for transcriptional regulation? J Intern Med 2007; 262:184-198.
    • (2007) J Intern Med , vol.262 , pp. 184-198
    • Ahmed, W.1    Ziouzenkova, O.2    Brown, J.3
  • 17
    • 0036773047 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart
    • Finck BN, Kelly DP. Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart. J Mol Cell Cardiol 2002; 34:1249-1257.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1249-1257
    • Finck, B.N.1    Kelly, D.P.2
  • 18
    • 77957188666 scopus 로고
    • Fenofibrate: Metabolism and species differences for peroxisome proliferation in cultured hepatocytes
    • Cornu-Chagnon MC, Dupont H, Edgar A. Fenofibrate: Metabolism and species differences for peroxisome proliferation in cultured hepatocytes. Fundam Appl Toxicol 1995; 26:63-74.
    • (1995) Fundam Appl Toxicol , vol.26 , pp. 63-74
    • Cornu-Chagnon, M.C.1    Dupont, H.2    Edgar, A.3
  • 19
    • 0033527569 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1
    • Delerive P, De Bosscher K, Besnard S, et al. Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J Biol Chem 1999; 274:32048-32054.
    • (1999) J Biol Chem , vol.274 , pp. 32048-32054
    • Delerive, P.1    De Bosscher, K.2    Besnard, S.3
  • 20
    • 66149149061 scopus 로고    scopus 로고
    • PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB
    • Bougarne N, Paumelle R, Caron S, et al. PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB. Proc Natl Acad Sci USA 2009; 106:7397-7402.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7397-7402
    • Bougarne, N.1    Paumelle, R.2    Caron, S.3
  • 21
    • 79957669555 scopus 로고    scopus 로고
    • Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPARalpha-independent mechanisms
    • Yamasaki D, Kawabe N, Nakamura H, et al. Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPARalpha-independent mechanisms. Eur J Cell Biol 2011; 90:657-664.
    • (2011) Eur J Cell Biol , vol.90 , pp. 657-664
    • Yamasaki, D.1    Kawabe, N.2    Nakamura, H.3
  • 22
    • 77955717702 scopus 로고    scopus 로고
    • Fenofibrate induces effective apoptosis in mantle cell lymphoma by inhibiting the TNFalpha/NF-kappaB signaling axis
    • Zak Z, Gelebart P, Lai R. Fenofibrate induces effective apoptosis in mantle cell lymphoma by inhibiting the TNFalpha/NF-kappaB signaling axis. Leukemia 2010; 24:1476-1486.
    • (2010) Leukemia , vol.24 , pp. 1476-1486
    • Zak, Z.1    Gelebart, P.2    Lai, R.3
  • 23
    • 0036943641 scopus 로고    scopus 로고
    • Cytotoxic effect of peroxisome proliferator fenofibrate on human HepG2 hepatoma cell line and relevant mechanisms
    • Jiao HL, Zhao BL. Cytotoxic effect of peroxisome proliferator fenofibrate on human HepG2 hepatoma cell line and relevant mechanisms. Toxicol Appl Pharmacol 2002; 185:172-179.
    • (2002) Toxicol Appl Pharmacol , vol.185 , pp. 172-179
    • Jiao, H.L.1    Zhao, B.L.2
  • 24
    • 7044247179 scopus 로고    scopus 로고
    • Budesonide exerts its chemopreventive efficacy during mouse lung tumorigenesis by modulating gene expressions
    • Yao R, Wang Y, Lemon WJ, Lubet RA, You M. Budesonide exerts its chemopreventive efficacy during mouse lung tumorigenesis by modulating gene expressions. Oncogene 2004; 23:7746-7752.
    • (2004) Oncogene , vol.23 , pp. 7746-7752
    • Yao, R.1    Wang, Y.2    Lemon, W.J.3    Lubet, R.A.4    You, M.5
  • 25
    • 0036317132 scopus 로고    scopus 로고
    • Prevention of mouse lung tumors by budesonide and its modulation of biomarkers
    • Pereira MA, Li Y, Gunning WT, et al. Prevention of mouse lung tumors by budesonide and its modulation of biomarkers. Carcinogenesis 2002; 23:1185-1192.
    • (2002) Carcinogenesis , vol.23 , pp. 1185-1192
    • Pereira, M.A.1    Li, Y.2    Gunning, W.T.3
  • 26
    • 0042090506 scopus 로고    scopus 로고
    • Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: Differential chemopreventive effect of budesonide in wild-type and mutant A/J mice
    • Wang Y, Zhang Z, Kastens E, Lubet RA, You M. Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: Differential chemopreventive effect of budesonide in wild-type and mutant A/J mice. Cancer Res 2003; 63:4389-4395.
    • (2003) Cancer Res , vol.63 , pp. 4389-4395
    • Wang, Y.1    Zhang, Z.2    Kastens, E.3    Lubet, R.A.4    You, M.5
  • 27
    • 74049137804 scopus 로고    scopus 로고
    • Prevention of cigarette smoke-induced lung tumors in mice by budesonide, phenethyl isothiocyanate, and N-acetylcysteine
    • Balansky R, Ganchev G, Iltcheva M, Steele VE, De Flora S. Prevention of cigarette smoke-induced lung tumors in mice by budesonide, phenethyl isothiocyanate, and N-acetylcysteine. Int J Cancer 2010; 126:1047-1054.
    • (2010) Int J Cancer , vol.126 , pp. 1047-1054
    • Balansky, R.1    Ganchev, G.2    Iltcheva, M.3    Steele, V.E.4    De Flora, S.5
  • 28
    • 0031048110 scopus 로고    scopus 로고
    • Glucocorticoid-induced long-term remission in primary cerebral lymphoma: Case report and review of the literature
    • Pirotte B, Levivier M, Goldman S, Brucher JM, Brotchi J, Hildebrand J. Glucocorticoid-induced long-term remission in primary cerebral lymphoma: Case report and review of the literature. J Neurooncol 1997; 32:63-69.
    • (1997) J Neurooncol , vol.32 , pp. 63-69
    • Pirotte, B.1    Levivier, M.2    Goldman, S.3    Brucher, J.M.4    Brotchi, J.5    Hildebrand, J.6
  • 29
    • 56849101027 scopus 로고    scopus 로고
    • Mechanisms regulating the susceptibility of hematopoietic malignancies to glucocorticoid-induced apoptosis
    • Sionov RV, Spokoini R, Kfir-Erenfeld S, Cohen O, Yefenof E. Mechanisms regulating the susceptibility of hematopoietic malignancies to glucocorticoid-induced apoptosis. Adv Cancer Res 2008; 101:127-248.
    • (2008) Adv Cancer Res , vol.101 , pp. 127-248
    • Sionov, R.V.1    Spokoini, R.2    Kfir-Erenfeld, S.3    Cohen, O.4    Yefenof, E.5
  • 30
    • 0034694892 scopus 로고    scopus 로고
    • Glucocorticoid-induced apoptosis in lymphocytes
    • Planey SL, Litwack G. Glucocorticoid-induced apoptosis in lymphocytes. Biochem Biophys Res Commun 2000; 279:307-312.
    • (2000) Biochem Biophys Res Commun , vol.279 , pp. 307-312
    • Planey, S.L.1    Litwack, G.2
  • 31
    • 59849129547 scopus 로고    scopus 로고
    • Molecular mechanisms regulating glucocorticoid sensitivity and resistance
    • Gross KL, Lu NZ, Cidlowski JA. Molecular mechanisms regulating glucocorticoid sensitivity and resistance. Mol Cell Endocrinol 2009; 300:7-16.
    • (2009) Mol Cell Endocrinol , vol.300 , pp. 7-16
    • Gross, K.L.1    Lu, N.Z.2    Cidlowski, J.A.3
  • 32
    • 0035866756 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats
    • Tanaka T, Kohno H, Yoshitani S, et al. Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats. Cancer Res 2001; 61:2424-2428.
    • (2001) Cancer Res , vol.61 , pp. 2424-2428
    • Tanaka, T.1    Kohno, H.2    Yoshitani, S.3
  • 33
    • 34248199412 scopus 로고    scopus 로고
    • Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer
    • Yokoyama Y, Xin B, Shigeto T, et al. Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer. Mol Cancer Ther 2007; 6:1379-1386.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1379-1386
    • Yokoyama, Y.1    Xin, B.2    Shigeto, T.3
  • 34
    • 34547138678 scopus 로고    scopus 로고
    • Peroxisomal proliferator-activated receptor-alpha-dependent inhibition of endothelial cell proliferation and tumorigenesis
    • Pozzi A, Ibanez MR, Gatica AE, et al. Peroxisomal proliferator-activated receptor-alpha-dependent inhibition of endothelial cell proliferation and tumorigenesis. J Biol Chem 2007; 282:17685-17695.
    • (2007) J Biol Chem , vol.282 , pp. 17685-17695
    • Pozzi, A.1    Ibanez, M.R.2    Gatica, A.E.3
  • 35
    • 38549095046 scopus 로고    scopus 로고
    • PPARalpha deficiency in inflammatory cells suppresses tumor growth
    • Kaipainen A, Kieran MW, Huang S, et al. PPARalpha deficiency in inflammatory cells suppresses tumor growth. PLoS ONE 2007; 2:e260.
    • (2007) PLoS ONE , vol.2
    • Kaipainen, A.1    Kieran, M.W.2    Huang, S.3
  • 36
    • 38949145780 scopus 로고    scopus 로고
    • PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition
    • Panigrahy D, Kaipainen A, Huang S, et al. PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition. Proc Natl Acad Sci USA 2008; 105:985-990.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 985-990
    • Panigrahy, D.1    Kaipainen, A.2    Huang, S.3
  • 37
    • 61449229273 scopus 로고    scopus 로고
    • Minireview: Latest perspectives on antiinflammatory actions of glucocorticoids
    • De Bosscher K, Haegeman G, Minireview: Latest perspectives on antiinflammatory actions of glucocorticoids. Mol Endocrinol 2009; 23:281-291.
    • (2009) Mol Endocrinol , vol.23 , pp. 281-291
    • De Bosscher, K.1    Haegeman, G.2
  • 38
    • 0036810356 scopus 로고    scopus 로고
    • Mechanisms involved in the side effects of glucocorticoids
    • Schacke H, Docke WD, Asadullah K. Mechanisms involved in the side effects of glucocorticoids. Pharmacol Ther 2002; 96:23-43.
    • (2002) Pharmacol Ther , vol.96 , pp. 23-43
    • Schacke, H.1    Docke, W.D.2    Asadullah, K.3
  • 39
    • 65849427529 scopus 로고    scopus 로고
    • Glucocorticoid resistance in inflammatory diseases
    • Barnes PJ, Adcock IM. Glucocorticoid resistance in inflammatory diseases. Lancet 2009; 373:1905-1917.
    • (2009) Lancet , vol.373 , pp. 1905-1917
    • Barnes, P.J.1    Adcock, I.M.2
  • 40
    • 4344700576 scopus 로고    scopus 로고
    • Glucocorticoid-induced apoptosis and glucocorticoid resistance: Molecular mechanisms and clinical relevance
    • Schmidt S, Rainer J, Ploner C, Presul E, Riml S, Kofler R. Glucocorticoid-induced apoptosis and glucocorticoid resistance: Molecular mechanisms and clinical relevance. Cell Death Differ 2004; 11:S45-S55.
    • (2004) Cell Death Differ , vol.11
    • Schmidt, S.1    Rainer, J.2    Ploner, C.3    Presul, E.4    Riml, S.5    Kofler, R.6
  • 41
    • 19844373387 scopus 로고    scopus 로고
    • Epidemiology of lung cancer: Looking to the future
    • Alberg AJ, Brock MV, Samet JM. Epidemiology of lung cancer: Looking to the future. J Clin Oncol 2005; 23:3175-3185.
    • (2005) J Clin Oncol , vol.23 , pp. 3175-3185
    • Alberg, A.J.1    Brock, M.V.2    Samet, J.M.3
  • 42
    • 0037037823 scopus 로고    scopus 로고
    • Lung cancer: An ever increasing store of in-depth basic knowledge and the beginning of its clinical application
    • Takahashi T. Lung cancer: An ever increasing store of in-depth basic knowledge and the beginning of its clinical application. Oncogene 2002; 21:6868-6869.
    • (2002) Oncogene , vol.21 , pp. 6868-6869
    • Takahashi, T.1
  • 44
    • 2942528630 scopus 로고    scopus 로고
    • Progression to androgen-independent LNCaP human prostate tumors: Cellular and molecular alterations
    • Zhou JR, Yu L, Zerbini LF, Libermann TA, Blackburn GL. Progression to androgen-independent LNCaP human prostate tumors: Cellular and molecular alterations. Int J Cancer 2004; 110:800-806.
    • (2004) Int J Cancer , vol.110 , pp. 800-806
    • Zhou, J.R.1    Yu, L.2    Zerbini, L.F.3    Libermann, T.A.4    Blackburn, G.L.5
  • 45
    • 82755186408 scopus 로고    scopus 로고
    • Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence
    • Larsson LG. Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence. Semin Cancer Biol 2011; 21:367-376.
    • (2011) Semin Cancer Biol , vol.21 , pp. 367-376
    • Larsson, L.G.1
  • 46
    • 0029846455 scopus 로고    scopus 로고
    • Abrogation of apoptosis induced by DNA-damaging agents in human bladder-cancer cell lines with p21/WAF1/CIP1 and/or p53 gene alterations
    • Kawasaki T, Tomita Y, Bilim V, Takeda M, Takahashi K, Kumanishi T. Abrogation of apoptosis induced by DNA-damaging agents in human bladder-cancer cell lines with p21/WAF1/CIP1 and/or p53 gene alterations. Int J Cancer 1996; 68:501-505.
    • (1996) Int J Cancer , vol.68 , pp. 501-505
    • Kawasaki, T.1    Tomita, Y.2    Bilim, V.3    Takeda, M.4    Takahashi, K.5    Kumanishi, T.6
  • 50
    • 0036241254 scopus 로고    scopus 로고
    • Chemotherapy regimens in advanced non-small-cell lung cancer: Recent randomized trials
    • Belani CP. Chemotherapy regimens in advanced non-small-cell lung cancer: Recent randomized trials. Clin Lung Cancer 2002; 3:S5-S9.
    • (2002) Clin Lung Cancer , vol.3
    • Belani, C.P.1
  • 52
    • 14644429018 scopus 로고    scopus 로고
    • Optimised glucocorticoid therapy: The sharpening of an old spear
    • Buttgereit F, Burmester GR, Lipworth BJ. Optimised glucocorticoid therapy: The sharpening of an old spear. Lancet 2005; 365:801-803.
    • (2005) Lancet , vol.365 , pp. 801-803
    • Buttgereit, F.1    Burmester, G.R.2    Lipworth, B.J.3
  • 53
    • 18144399332 scopus 로고    scopus 로고
    • The human glucocorticoid receptor: One gene, multiple proteins and diverse responses
    • Zhou J, Cidlowski JA. The human glucocorticoid receptor: One gene, multiple proteins and diverse responses. Steroids 2005; 70:407-417.
    • (2005) Steroids , vol.70 , pp. 407-417
    • Zhou, J.1    Cidlowski, J.A.2
  • 54
    • 0026540753 scopus 로고
    • Glucocorticoids in cancer therapy
    • Coleman RE. Glucocorticoids in cancer therapy. Biotherapy 1992; 4:37-44.
    • (1992) Biotherapy , vol.4 , pp. 37-44
    • Coleman, R.E.1
  • 55
    • 33645991782 scopus 로고    scopus 로고
    • Glucocorticoid use in prostate cancer and other solid tumours: Implications for effectiveness of cytotoxic treatment and metastases
    • Herr I, Pfitzenmaier J. Glucocorticoid use in prostate cancer and other solid tumours: Implications for effectiveness of cytotoxic treatment and metastases. Lancet Oncol 2006; 7:425-430.
    • (2006) Lancet Oncol , vol.7 , pp. 425-430
    • Herr, I.1    Pfitzenmaier, J.2
  • 56
    • 33947500218 scopus 로고    scopus 로고
    • Tumor suppressor activity of glucocorticoid receptor in the prostate
    • Yemelyanov A, Czwornog J, Chebotaev D, et al. Tumor suppressor activity of glucocorticoid receptor in the prostate. Oncogene 2007; 26:1885-1896.
    • (2007) Oncogene , vol.26 , pp. 1885-1896
    • Yemelyanov, A.1    Czwornog, J.2    Chebotaev, D.3
  • 57
    • 42649107218 scopus 로고    scopus 로고
    • Systematic review of the clinical effect of glucocorticoids on nonhematologic malignancy
    • Keith BD. Systematic review of the clinical effect of glucocorticoids on nonhematologic malignancy. BMC Cancer 2008; 8:84.
    • (2008) BMC Cancer , vol.8 , pp. 84
    • Keith, B.D.1
  • 59
    • 0033965919 scopus 로고    scopus 로고
    • Chemoprevention of pulmonary carcinogenesis by brief exposures to aerosolized budesonide or beclomethasone dipropionate and by the combination of aerosolized budesonide and dietary myo-inositol
    • Wattenberg LW, Wiedmann TS, Estensen RD, et al. Chemoprevention of pulmonary carcinogenesis by brief exposures to aerosolized budesonide or beclomethasone dipropionate and by the combination of aerosolized budesonide and dietary myo-inositol. Carcinogenesis 2000; 21:179-182.
    • (2000) Carcinogenesis , vol.21 , pp. 179-182
    • Wattenberg, L.W.1    Wiedmann, T.S.2    Estensen, R.D.3
  • 60
    • 69449089335 scopus 로고    scopus 로고
    • Prenatal N-acetylcysteine prevents cigarette smoke-induced lung cancer in neonatal mice
    • Balansky R, Ganchev G, Iltcheva M, Steele VE, De Flora S. Prenatal N-acetylcysteine prevents cigarette smoke-induced lung cancer in neonatal mice. Carcinogenesis 2009; 30:1398-1401.
    • (2009) Carcinogenesis , vol.30 , pp. 1398-1401
    • Balansky, R.1    Ganchev, G.2    Iltcheva, M.3    Steele, V.E.4    De Flora, S.5
  • 61
    • 77957947159 scopus 로고    scopus 로고
    • Budesonide versus placebo in high-risk population with screen-detected lung nodules: Rationale, design and methodology
    • Lazzeroni M, Guerrieri-Gonzaga A, Serrano D, et al. Budesonide versus placebo in high-risk population with screen-detected lung nodules: Rationale, design and methodology. Contemp Clin Trials 2010; 31:612-619.
    • (2010) Contemp Clin Trials , vol.31 , pp. 612-619
    • Lazzeroni, M.1    Guerrieri-Gonzaga, A.2    Serrano, D.3
  • 62
    • 78650847149 scopus 로고    scopus 로고
    • Randomized phase II trial of inhaled budesonide versus placebo in high-risk individuals with CT screen-detected lung nodules
    • Veronesi G, Szabo E, Decensi A, et al. Randomized phase II trial of inhaled budesonide versus placebo in high-risk individuals with CT screen-detected lung nodules. Cancer Prev Res (Phila) 2011; 4:34-42.
    • (2011) Cancer Prev Res (Phila) , vol.4 , pp. 34-42
    • Veronesi, G.1    Szabo, E.2    Decensi, A.3
  • 63
    • 0018888058 scopus 로고
    • Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens
    • Reddy JK, Azarnoff DL, Hignite CE. Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature 1980; 283:397-398.
    • (1980) Nature , vol.283 , pp. 397-398
    • Reddy, J.K.1    Azarnoff, D.L.2    Hignite, C.E.3
  • 64
    • 0031418657 scopus 로고    scopus 로고
    • Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-146,43
    • Peters JM, Cattley RC, Gonzalez FJ. Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-146, 43. Carcinogenesis 1997; 18:2029-2033.
    • (1997) Carcinogenesis , vol.18 , pp. 2029-2033
    • Peters, J.M.1    Cattley, R.C.2    Gonzalez, F.J.3
  • 65
    • 3543138832 scopus 로고    scopus 로고
    • Inhibition of melanoma metastases by fenofibrate
    • Grabacka M, Placha W, Plonka PM, et al. Inhibition of melanoma metastases by fenofibrate. Arch Dermatol Res 2004; 296:54-58.
    • (2004) Arch Dermatol Res , vol.296 , pp. 54-58
    • Grabacka, M.1    Placha, W.2    Plonka, P.M.3
  • 66
    • 33744797915 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha activation decreases metastatic potential of melanoma cells in vitro via down-regulation of Akt
    • Grabacka M, Plonka PM, Urbanska K, Reiss K. Peroxisome proliferator-activated receptor alpha activation decreases metastatic potential of melanoma cells in vitro via down-regulation of Akt. Clin Cancer Res 2006; 12:3028-3036.
    • (2006) Clin Cancer Res , vol.12 , pp. 3028-3036
    • Grabacka, M.1    Plonka, P.M.2    Urbanska, K.3    Reiss, K.4
  • 67
    • 0040370216 scopus 로고    scopus 로고
    • Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest
    • Zuo Z, Urban G, Scammell JG, et al. Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest. Biochemistry 1999; 38:8849-8857.
    • (1999) Biochemistry , vol.38 , pp. 8849-8857
    • Zuo, Z.1    Urban, G.2    Scammell, J.G.3
  • 68
    • 0034669037 scopus 로고    scopus 로고
    • Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells
    • Sengupta S, Vonesch JL, Waltzinger C, Zheng H, Wasylyk B. Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells. EMBO J 2000; 19:6051-6064.
    • (2000) EMBO J , vol.19 , pp. 6051-6064
    • Sengupta, S.1    Vonesch, J.L.2    Waltzinger, C.3    Zheng, H.4    Wasylyk, B.5
  • 69
    • 3442876677 scopus 로고    scopus 로고
    • Dysfunctional interaction of C/EBPalpha and the glucocorticoid receptor in asthmatic bronchial smooth-muscle cells
    • Roth M, Johnson PR, Borger P, et al. Dysfunctional interaction of C/EBPalpha and the glucocorticoid receptor in asthmatic bronchial smooth-muscle cells. N Engl J Med 2004; 351:560-574.
    • (2004) N Engl J Med , vol.351 , pp. 560-574
    • Roth, M.1    Johnson, P.R.2    Borger, P.3
  • 70
    • 0031891862 scopus 로고    scopus 로고
    • Glucocorticoids stimulate p21 gene expression by targeting multiple transcriptional elements within a steroid responsive region of the p21waf1/cip1 promoter in rat hepatoma cells
    • Cha HH, Cram EJ, Wang EC, Huang AJ, Kasler HG, Firestone GL. Glucocorticoids stimulate p21 gene expression by targeting multiple transcriptional elements within a steroid responsive region of the p21waf1/cip1 promoter in rat hepatoma cells. J Biol Chem 1998; 273:1998-2007.
    • (1998) J Biol Chem , vol.273 , pp. 1998-2007
    • Cha, H.H.1    Cram, E.J.2    Wang, E.C.3    Huang, A.J.4    Kasler, H.G.5    Firestone, G.L.6
  • 71
    • 0031939946 scopus 로고    scopus 로고
    • Role of the CCAAT/enhancer binding protein-alpha transcription factor in the glucocorticoid stimulation of p21waf1/cip1 gene promoter activity in growth-arrested rat hepatoma cells
    • Cram EJ, Ramos RA, Wang EC, Cha HH, Nishio Y, Firestone GL. Role of the CCAAT/enhancer binding protein-alpha transcription factor in the glucocorticoid stimulation of p21waf1/cip1 gene promoter activity in growth-arrested rat hepatoma cells. J Biol Chem 1998; 273:2008-2014.
    • (1998) J Biol Chem , vol.273 , pp. 2008-2014
    • Cram, E.J.1    Ramos, R.A.2    Wang, E.C.3    Cha, H.H.4    Nishio, Y.5    Firestone, G.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.