Chemoprevention of pulmonary carcinogenesis by aerosolized budesonide in female A/J mice

Cancer Research

Volumn 57, Issue 24, 1997, Pages 5489-5492

  Wattenberg, Lee W ^a   Wiedmann, Timothy S ^b   Estensen, Richard D ^a   Zimmerman, Cheryl L ^b   Steele, Vernon E ^c   Kelloff, Gary J ^c  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; BUDESONIDE; GLUCOCORTICOID;

AEROSOL; ANIMAL TISSUE; ARTICLE; CHEMOPROPHYLAXIS; CONCENTRATION RESPONSE; DOSE CALCULATION; DOSE RESPONSE; FEMALE; HUMAN CELL; INHALATIONAL DRUG ADMINISTRATION; LUNG ADENOMA; LUNG CARCINOGENESIS; MOUSE; NEBULIZATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SPLEEN WEIGHT;

ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; ANTICARCINOGENIC AGENTS; BENZO(A)PYRENE; BODY WEIGHT; BUDESONIDE; CARCINOGENS; FEMALE; LUNG NEOPLASMS; MICE; MICE, INBRED A; PARTICLE SIZE;

EID: 0031454659     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Estensen, R. D., and Wattenberg, L. W. Studies of chemopreventive effects of myo-inositol on benzo(a)pyrene-induced neoplasia of the lung and forestomach of female A/J mice. Carcinogenesis (Lond.), 14: 1975-1977, 1993.
2. Wattenberg, L. W. Chalcones, myo-inositol and other novel inhibitors of pulmonary carcinogenesis. J. Cell. Biochem., 22 (Suppl.): 1162-1168, 1995.
3. Wattenberg, L. W. Prevention-therapy-basic science and the resolution of the cancer problem presidential address. Cancer Res., 53: 5890-5896, 1993.
4. Wattenberg, L. W., and Estensen, R. D. Chemopreventive effects of myo-inositol and dexamethasone on benzo(a)pyrene and 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone-induced pulmonary carcinogenesis in female A/J mice. Cancer Res., 56: 5132-5135, 1996.
5. Belman, S., and Troll, W. The inhibition of croton oil-promoted mouse skin tumorigenesis by steroid hormones. Cancer Res., 32: 450-454, 1972.
6. Verma, A. K., Garcia, C. T., Ashendel, C. L., and Boutwell, R. K. Inhibition of 7-bromomethylbenz(a)anthracene-promoted mouse skin tumor formation by retinoic acid and dexamethasone. Cancer Res., 43: 3045-3049, 1983.
7. Kresch, M. J., and Gross, I. The biochemistry of fetal lung development. Clin Perinatol., 14: 481-507, 1987.
8. Gross, I. Regulation of fetal lung maturation. Am. J. Physiol., 259: L337-L344, 1990.
9. Jonat, C., Rahmsdorf, H. J., Park, K-K., Cato, A. C. B., Gebel, S., Ponta, H., and Herrlich, P. Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell. 62: 1189-1204, 1990.
10. Mouhieddine, O. B., Cazals, V., Kuto, E., LeBouc, Y., and Clement, A. Glucocorticoid-induced growth arrest of lung alveolar epithelial cells is associated with increased production of insulin-like growth factor binding protein-2. Endocrinology, 137: 287-295, 1996.
11. Wu, C-C., Croxtall, J. D., Perretti, M., Bryant, C. E., Thiemermann, C., Flower, R. J., and Vane, J. R. Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. Proc. Natl. Acad. Sci. USA, 92: 3473-3477, 1995.
12. Lipworth, B. J. Clinical pharmacology of corticosteroids in bronchial asthma. Pharmacol. Ther., 6: 173-209, 1993.
13. Barnes, P. J. Inhaled glucocorticoids for asthma. N. Engl. J. Med., 332: 868-875, 1995.
14. Barnes, P. J. Inhaled glucocorticoids: new developments relevant to updating asthma management guidelines. Respir. Med., 90: 379-384, 1996.
15. Ryrfelt, A., Andersson, P., Edsbacker, S., Tonnesson, M., Davies, D., and Pauwels, R. Pharmacokinetics and metabolism of budesonide, a selective glucocorticoid. Eur. J. Respir, Dis., 63 (Suppl. 122): 86-95, 1982.
16. Pederson, S., and Hansen, O. R. Budesonide treatment of moderate and severe asthma in children: a dose-response study. J. Allerg. Clin. Immunol. 95: 29-33, 1994.
17. Wattenberg, L. W., and Estensen, R. D. Studies of chemopreventive effects of budesonide on benzoapyrene-induced neoplasia of the lung in female A/J mice. Carcinogenesis (Lond.), 18: 2015-2017, 1997.
18. Shimkin, M. B. Induced pulmonary tumors in mice, II. Reactions of lungs in strain A mice to carcinogenic hydrocarbons. Arch. Pathol., 29: 235-255, 1940.
19. Shimkin, M. B. Pulmonary tumors in experimental animals. Adv. Cancer Res., 3: 223-267, 1955.
20. Guyton, A. C. Measurement of the respiratory volumes of laboratory animals. Am. J. Physiol., 150: 70-77, 1947.
21. Tuli, J. S., Smith, J. A., and Morton, D. B. Corticosterone, adrenal and spleen weight in mice after tail bleeding, and its effect on nearby animals. Lab. Anim., 29: 90-95, 1995.
22. Yamamoto, H., Fuji, K., and Hayakawa, T. Inhibitory effect of cold stress on lung tumors induced by 7,12-dimethylbenzαanthracene in mice. J. Cancer Res. Clin. Oncol., 121: 393-396, 1995.
23. Bhatnagar, S. and Meaney, M. J. Hypothalamic-pituitury-adrenal function in chronic intermittently cold-stressed neonatally handled and non handled rats. J. Neuroendocrinol., 7: 97-108, 1995.
24. Levine, S., Haltmeyer, G. C., Karas, G. C., and Denenberg, V. H. Physiological and behavioral effects of infantile stimulation. Physiol. Behav., 2: 55-59. 1967.