Glucocorticoids induce Kaposi's sarcoma cell proliferation through the regulation of transforming growth factor-β

Blood

Volumn 89, Issue 5, 1997, Pages 1491-1500

  Cai, Jie ^b   Zheng, Tong ^b   Lotz, Martin ^b   Zhang, Ya ^b   Masood, Rizwan ^b   Gill, Parkash ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; GLUCOCORTICOID; INTERLEUKIN 1; INTERLEUKIN 6; ONCOSTATIN M; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL PROLIFERATION; GROWTH INHIBITION; GROWTH STIMULATION; HORMONAL REGULATION; HUMAN; HUMAN CELL; IMMUNOREGULATION; KAPOSI SARCOMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR GROWTH;

EID: 0031034054     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.5.1491     Document Type: Article

References (53)

1. Biggar RJ, Rabkin CS: The epidemiology of AIDS-related neoplasms. Hematol Oncol Clin North Am 10:997, 1996
2. Centers for Disease Control and Prevention: HIV/AIDS Surveillance Report. February 1993, p 1
3. Gill PS, Hamilton A, Naidu Y: Epidemic (AIDS-related) Kaposi's sarcoma: Epidemiology, pathogenesis and treatment. AIDS Updates 7:1, 1994
4. Scully PA, Steinman HK, Kennedy C, Trueblood K, Frisman DM, Voland JR: AIDS-related Kaposi's sarcoma displays differential expression of endothelial surface antigens. Am J Pathol 130:244, 1988
5. Weich HA, Salahuddin SZ, Gill PS, Nakamura S, Gallo R, Folkmann J: AIDS-associated Kaposi's sarcoma-derived cells in long-term culture express and synthesize smooth muscle alpha-actin. Am J Pathol 139:1251, 1991
6. Nakamura S, Salahuddin SZ, Biberfeld P, Ensoli B, Markham PD, Wong-Staal F, Gallo RC: Kaposi's sarcoma cells: Long term culture with growth factor from retrovirus-infected CD4+ T cells. Science 242:426, 1988
7. Lunardi-Iskandar, Gill PS, Lam VH, Zeman RA, Michaels F, Mann DL, Reitz MS, Kaplan M, Bememan ZN, Carter D, Bryant JL, Gallo RC: Isolation and characterization of an immortal neoplastic cell line (KS Y-1) from AIDS-associated Kaposi's sarcoma. J Natl Cancer Inst 87:974, 1995
8. Louie S, Cai J, Law R, Lin G, Lunardi-Iskandar Y, Jung B, Masood R, Gill PS: The effect of interleukin-1 and interleukin-1 antagonist in AIDS-Kaposi's sarcoma. J Acquir Immune Defic Syndr Hum Retrovirol 4:455, 1995
9. Miles SA, Rezai AR, Salazar-Gonzalez JF, Meyden MV, Stevens RH, Logan DM, Mitsuyasu RT, Taga T, Hirano T, Kishimoto T, Martinez-Maza O: AIDS-Kaposi's sarcoma-derived cells produce and respond to interleukin-6. Proc Natl Acad Sci USA 87:4068. 1990
10. Nair BC, DeVico AL, Nakamura S, Copeland TD, Chen Y, Patel A, o'Neill T, Oroszlan S, Gallo RC, Sarngadharan MG: Identification of major growth factor for AIDS-KS cells as oncostaing-M. Science 255:1430, 1992
11. Ensoli B, Nakamura S, Salahuddin SZ, Biberfeld P, Larsson L, Beaver B, Wong-Staal F, Gallo RC: AIDS-Kaposi's sarcoma-derived cells express cytokines and autocrine and paracrine growth effects. Science 243:223, 1989
12. Salahuddin SZ, Nakamura S, Biberfeld P, Kaplan MH, Markham PD, Larsson L, Gallo RC: Angiogenic properties of Kaposi's sarcoma derived cells after long-term culture in vitro. Science 242:430, 1983
13. Weindel K, Marme D, Weich HA: AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor. Biochem Biophys Res Commun 183:1167, 1992
14. Ensoli B, Barillari G, Salahuddin SZ, Gallo RC, Wong-Staal F: Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature 345:84, 1989
15. Vogel J, Hinrichs SH, Reynolds RK, Luciw PA, Jay G: The HIV tat gene induces dermal lesions resembling Kaposi's sarcoma in transgenic mice. Nature 335:606, 1988
16. Penn I: Kaposi's sarcoma in organ transplant recipients. Report of 20 cases. Transplantation 27:8, 1979
17. Harwood AR, Osoba D, Hofstader SL, Goldstein MB, Cardella CJ, Holecek MJ, Kunynetz R, Gianmmarco RA: Kaposi's sarcoma in renal transplant recipients. Am J Med 67:759, 1979
18. Schottstaedt MW, Hurd ER, Stone MJ: Kaposi's sarcoma in the rheumatoid arthritis. Am J Med 82:1021, 1987
19. Klepp O, Dahl O, Stenwig JT: Association of Kaposi's sarcoma and prior immunosuppressive therapy. Cancer 42:2626, 1978
20. Gill PS, Loureiro C, Bernstein-Singer M, Rarick MU, Sattler F, Levine AM: Clinical effect of glucocorticoids on Kaposi's sarcoma related to the acquired immunodeficiency syndrome (AIDS). Ann Intern Med 110:937, 1989
21. Schulhafer EP, Grossman ME, Fagin G, Bell M: Steroid-induced Kaposi's sarcoma in a patient with pre-AlDS. Am J Med 82:313, 1987
22. Real FX, Krown SE, Kroziner B: Steroid-related development of Kaposi's sarcoma in a homosexual man with Burkitt's lymphoma. Am J Med 80:119, 1986
23. Guo WX, Gill PS, Antakly T: Inhibition of AIDS-Kaposi's sarcoma cell proliferation following retinoic acid receptor activation. Cancer Res 55:823, 1995
24. Antakly T, Raquidan D, O'Donnell D, Katnick L: Regulation of glucocorticoid receptor expression. Use of a specific radioimmunoassay and antiserum to synthetic peptide of the N-terminal domain. Endocrinology 126:1821, 1990
25. 1. J Biol Chem 263:208, 1988
26. Ten Dijke P, Iwata KK, Goddard C, Pieler C, Canalis E, McCarthy TL, Centrella M: Recombinant transforming growth factor type beta 3: Biological activities and receptor-binding properties in isolated bone cells. Mol Cell Biol 10:4473, 1990
27. Knabbe C, Lippman ME, Wakcfield LM, Flanders KC, Kasid A, Derynck R, Dickson RB: Evidence that transforming growth factor is a hormonally regulated negative growth factor in human breast cancer cells. Cell 48:417, 1987
28. Breuninger L, Goonewardene IM, Dempsey WC, Murasko DM: Monocyte culture and adherence modifies LPS-induced IL-6 production and inhibition by hydrocortisone. Clin Immunol Immunopathol 72:264, 1994
29. Arzt E, Sauer J, Pollmacher T, Labeur M, Holsboer F, Reul JM, Stalla GK: Glucocorticoids suppress interleukin-1 receptor antagonist synthesis following induction by endocytosis. Endocrinology 134:672, 1994
30. Brogi E, Wu T, Namiki A, Isner JM: Indirect angiogenic cytekines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulations VEGF expression only. Circulation 90:649, 1994
31. Battegay E, Raines EW, Seifert RA, Bowen-Pope DF, Ross R: TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell 63:515, 1990
32. Lyons RM, Keski-oja L, Moses HL: Proteolytic activation of latent transforming growth factor-β from fibroblast-conditioned medium. J Cell Biol 106: l659, 1988.
33. Lyons RM, Gentry LE, Purchio AF, Moses HL: Mechanism of activation of latent recombinant transforming growth factor β by plasmin. J Cell Biol 100:1361, 1990
34. Roldan AL, Cubellis MV, Masucci MT, Behrendt N, Lund LR, Danø K, Appella E, Blasi F: Cloning- and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. EMBO J 9:467, 1990
35. Granelli-Pipemo A, Reich E: A study of proteases and protease-inhibitor complexes in biological fluids. J Exp Med 701:223, 1978
36. r ∼54,000 plasminogeh activator inhibitor in human neoplastic cell lines, studied with monoclonal antibodies. Mol Cell Endocrinol 34:137, 1986
37. Busso N, Belin D, Failly-Crepin C, Vassalli JD: Plasminogen activators and their inhibitors in a human mammary cell line (HBL-100). Modulation by glucocorticoids. J Biol Chem 261:9309, 1986
38. Seifert SC, Gelehrter TD: Mechanism of dexamethasone inhibition of plasminogen activator in rat hepatoma cells. Proc Natl Acad Sci USA 75:6130, 1978
39. van Zonneveld AJ, Curriden SA, Loskutoff DJ: Type 1 plasminogen activator inhibitor gene: Functional analysis and glucocorticoid regulation of its promoter. Proc Natl Acad Sci USA 85:5525, 1988
40. Freeman SN, Rennie PS, Chao J, Lund LR, Andreasen PA: Urokinase- and tissue-type plasminogen activators are suppressed by cortisol in the involving prostate of castrated rats. Biochem J 269:189, 1990
41. DePergola G, DeMitrio V, Cignarelli M, Garruit G, Giorgino F, Meola M, Giorgino R: Inverse relationship between cortisol excretion rate and plasminogen activator inhibitor-1 (PAI-1) antigen and activity in premenopausal obese women. Int J Obes 15:619, 1991
42. Blei F, Wilson E, Mignatti P, Rifkin DB: Mechanism of action of angiostatic steroids: Suppression of plasminogen activator activity via stimulation of plasminogen activator inhibitor synthesis. J Cell Physiol 155:568, 1993
43. Dicheck DA, Lee SW, Nguyen NH: Characterization of recombinant plasminogen activator production by primate endothelial cells transduced with retroviral vector. Blood 84:504, 1994
44. Bristol LA, Ruscetti FW, Brady DT, Durum SK: IL:1α induces expression of active transforming growth factor-β in nonproliferating T-cells in a post-transcriptional mechanism. J Immunol 145:4108, 1990
45. Samaniego F, Markham PD, Gallo RC, Ensoli B: Inflammatory cytokines induces AlDS-Kaposi's sarcoma-derived spindle cells to produce and release basic fibrobiastic growth factor and enhance Kaposi's sarcoma-like lesion formation in nude mice. J Immunol 154:3582, 1995
46. 46: Lotz M, Ranheim E, Kipps TJ: Transforming growth factor β as endogenous growth inhibitor of chronic lymphocytic leukemia B cells. J Exp Med 179:999, 1994
47. Danielpour D, Dart LL, Flanders KC, Roberts AB, Sporn MB: Immunodetection and quantitation of the two forms of transforming growth factor-beta (TGF-β1 and TGF-β2) secreted by cells in culture. J Cell Physiol 138:79, 1989
48. Wu SP, Theodorescu D, Kerbel RS, Willson JK, Mulder KM, Humphrey LE, Brattain MG: TGF-beta 1 is an autocrine negative growth regulator of human colon carcinoma FET cells in vivo as revelated by transfection of an antisense expression vector. J Cell Biol 116:187, 1992
49. Glick AB, Kulkarni AB, Tennebaum T, Hennings H, Flanders KC, O'Reilly M, Sporn MB, Karrison S, Yuspa SH: Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion. Proc Natl Acad Sci USA 90:6076, 1993
50. Ogrady P, Lijnen HR, Duff MJ: Multiple forms of plasminogen activator in human breast tumors. Cancer Res 45:6216, 1985
51. Wun TC, Ossowski L, Reich E: A proenzyme form of urokinase. J Biol Chem 257:7262, 1982
52. Cubellis, MV, Wun TC, Blasi F: Receptor mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1. EMBO J 9:1079, 1990
53. Mignatti P, Mazzieri R, Rifkin DB: Expression of urokinase receptor in vascular endothelial cells is stimulated by basic fibroblastic growth fator. J Cell Biol 113:1193, 1991