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Volumn 104, Issue 2, 2014, Pages 144-155

Differential gene expression analysis in CCLE lesions provides new insights regarding the genetics basis of skin vs. Systemic disease

Author keywords

Apoptosis; Autoimmune; Cutaneous lupus; Gene expression; Interferon; Microarray

Indexed keywords

ADULT; AUTOIMMUNE DISEASES; CELL CULTURE; FEMALE; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; GENETICS; HUMAN; LUPUS ERYTHEMATOSUS, DISCOID; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICROARRAY ANALYSIS; MIDDLE AGED; MULTIGENE FAMILY; PATHOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN;

EID: 84906050368     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2014.06.003     Document Type: Article
Times cited : (44)

References (96)
  • 1
    • 33750067967 scopus 로고    scopus 로고
    • Cutaneous lupus erythematosus: understanding of clinical features, genetic basis, and pathobiology of disease guides therapeutic strategies
    • Lee H.J., Sinha A.A. Cutaneous lupus erythematosus: understanding of clinical features, genetic basis, and pathobiology of disease guides therapeutic strategies. Autoimmunity 2006, 39:433-444.
    • (2006) Autoimmunity , vol.39 , pp. 433-444
    • Lee, H.J.1    Sinha, A.A.2
  • 2
    • 80052057054 scopus 로고    scopus 로고
    • Recent advances in cytokines in cutaneous and systemic lupus erythematosus
    • Mikita N., Ikeda T., Ishiguro M., Furukawa F. Recent advances in cytokines in cutaneous and systemic lupus erythematosus. J. Dermatol. 2011, 38:839-849.
    • (2011) J. Dermatol. , vol.38 , pp. 839-849
    • Mikita, N.1    Ikeda, T.2    Ishiguro, M.3    Furukawa, F.4
  • 3
    • 77955541911 scopus 로고    scopus 로고
    • Pathogenesis of cutaneous lupus erythematosus: common and different features in distinct subsets
    • Wenzel J., Zahn S., Tuting T. Pathogenesis of cutaneous lupus erythematosus: common and different features in distinct subsets. Lupus 2010, 19:1020-1028.
    • (2010) Lupus , vol.19 , pp. 1020-1028
    • Wenzel, J.1    Zahn, S.2    Tuting, T.3
  • 4
    • 84875919149 scopus 로고    scopus 로고
    • Immunologic and genetic considerations of cutaneous lupus erythematosus: a comprehensive review
    • Yu C., Chang C., Zhang J. Immunologic and genetic considerations of cutaneous lupus erythematosus: a comprehensive review. J. Autoimmun. 2013, 41:34-45.
    • (2013) J. Autoimmun. , vol.41 , pp. 34-45
    • Yu, C.1    Chang, C.2    Zhang, J.3
  • 5
    • 0032898385 scopus 로고    scopus 로고
    • Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: relations with disease activity, antibodies to double stranded DNA, and neutropenia
    • Courtney P.A., Crockard A.D., Williamson K., Irvine A.E., Kennedy R.J., Bell A.L. Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: relations with disease activity, antibodies to double stranded DNA, and neutropenia. Ann. Rheum. Dis. 1999, 58:309-314.
    • (1999) Ann. Rheum. Dis. , vol.58 , pp. 309-314
    • Courtney, P.A.1    Crockard, A.D.2    Williamson, K.3    Irvine, A.E.4    Kennedy, R.J.5    Bell, A.L.6
  • 6
    • 0028330345 scopus 로고
    • Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus
    • Emlen W., Niebur J., Kadera R. Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J. Immunol. 1994, 152:3685-3692.
    • (1994) J. Immunol. , vol.152 , pp. 3685-3692
    • Emlen, W.1    Niebur, J.2    Kadera, R.3
  • 9
    • 0035724839 scopus 로고    scopus 로고
    • Apoptosis in different cutaneous manifestations of lupus erythematosus
    • Baima B., Sticherling M. Apoptosis in different cutaneous manifestations of lupus erythematosus. Br. J. Dermatol. 2001, 144:958-966.
    • (2001) Br. J. Dermatol. , vol.144 , pp. 958-966
    • Baima, B.1    Sticherling, M.2
  • 11
    • 36949018686 scopus 로고    scopus 로고
    • Clinical manifestations of cutaneous lupus erythematosus
    • Kuhn A., Sticherling M., Bonsmann G. Clinical manifestations of cutaneous lupus erythematosus. J. Dtsch. Dermatol. Ges. 2007, 5:1124-1137.
    • (2007) J. Dtsch. Dermatol. Ges. , vol.5 , pp. 1124-1137
    • Kuhn, A.1    Sticherling, M.2    Bonsmann, G.3
  • 13
    • 84992238340 scopus 로고    scopus 로고
    • Cutaneous manifestations of systemic lupus erythmatosus
    • Ghosh A. Cutaneous manifestations of systemic lupus erythmatosus. Indian J. Rheumatol. 2007, 2:156-164.
    • (2007) Indian J. Rheumatol. , vol.2 , pp. 156-164
    • Ghosh, A.1
  • 14
    • 0019831847 scopus 로고
    • Distinctive cutaneous subsets in the spectrum of lupus erythematosus
    • Gilliam J.N., Sontheimer R.D. Distinctive cutaneous subsets in the spectrum of lupus erythematosus. J. Am. Acad. Dermatol. 1981, 4:471-475.
    • (1981) J. Am. Acad. Dermatol. , vol.4 , pp. 471-475
    • Gilliam, J.N.1    Sontheimer, R.D.2
  • 15
    • 79957587778 scopus 로고    scopus 로고
    • Cutaneous lupus erythematosus and the association with systemic lupus erythematosus: a population-based cohort of 1088 patients in Sweden
    • Gronhagen C.M., Fored C.M., Granath F., Nyberg F. Cutaneous lupus erythematosus and the association with systemic lupus erythematosus: a population-based cohort of 1088 patients in Sweden. Br. J. Dermatol. 2011, 164:1335-1341.
    • (2011) Br. J. Dermatol. , vol.164 , pp. 1335-1341
    • Gronhagen, C.M.1    Fored, C.M.2    Granath, F.3    Nyberg, F.4
  • 16
    • 0035059967 scopus 로고    scopus 로고
    • Molecular genetics of cutaneous lupus erythematosus
    • Millard T.P., McGregor J.M. Molecular genetics of cutaneous lupus erythematosus. Clin. Exp. Dermatol. 2001, 26:184-191.
    • (2001) Clin. Exp. Dermatol. , vol.26 , pp. 184-191
    • Millard, T.P.1    McGregor, J.M.2
  • 17
    • 0031040680 scopus 로고    scopus 로고
    • Epidemiology and socioeconomic impact of skin disease in lupus erythematosus
    • Tebbe B., Orfanos C.E. Epidemiology and socioeconomic impact of skin disease in lupus erythematosus. Lupus 1997, 6:96-104.
    • (1997) Lupus , vol.6 , pp. 96-104
    • Tebbe, B.1    Orfanos, C.E.2
  • 18
    • 38449109473 scopus 로고    scopus 로고
    • Cutaneous lupus: insights into pathogenesis and disease classification
    • Werth V.P. Cutaneous lupus: insights into pathogenesis and disease classification. Bull. NYU Hosp. Jt. Dis. 2007, 65:200-204.
    • (2007) Bull. NYU Hosp. Jt. Dis. , vol.65 , pp. 200-204
    • Werth, V.P.1
  • 19
    • 0014235772 scopus 로고
    • The sex- and age-distributions of chronic discoid lupus erythematosus in four countries. Possible aetiological and pathogenetic significance
    • Burch P.R., Rowell N.R. The sex- and age-distributions of chronic discoid lupus erythematosus in four countries. Possible aetiological and pathogenetic significance. Acta Derm. Venereol. 1968, 48:33-46.
    • (1968) Acta Derm. Venereol. , vol.48 , pp. 33-46
    • Burch, P.R.1    Rowell, N.R.2
  • 20
    • 47949089923 scopus 로고    scopus 로고
    • Association of a gene expression profile from whole blood with disease activity in systemic lupus erythaematosus
    • Nikpour M., Dempsey A.A., Urowitz M.B., Gladman D.D., Barnes D.A. Association of a gene expression profile from whole blood with disease activity in systemic lupus erythaematosus. Ann. Rheum. Dis. 2008, 67:1069-1075.
    • (2008) Ann. Rheum. Dis. , vol.67 , pp. 1069-1075
    • Nikpour, M.1    Dempsey, A.A.2    Urowitz, M.B.3    Gladman, D.D.4    Barnes, D.A.5
  • 21
    • 0042329609 scopus 로고    scopus 로고
    • The central role of dendritic cells and interferon-alpha in SLE
    • Pascual V., Banchereau J., Palucka A.K. The central role of dendritic cells and interferon-alpha in SLE. Curr. Opin. Rheumatol. 2003, 15:548-556.
    • (2003) Curr. Opin. Rheumatol. , vol.15 , pp. 548-556
    • Pascual, V.1    Banchereau, J.2    Palucka, A.K.3
  • 26
    • 0141986842 scopus 로고    scopus 로고
    • Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray
    • Han G.M., Chen S.L., Shen N., Ye S., Bao C.D., Gu Y.Y. Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray. Genes Immun. 2003, 4:177-186.
    • (2003) Genes Immun. , vol.4 , pp. 177-186
    • Han, G.M.1    Chen, S.L.2    Shen, N.3    Ye, S.4    Bao, C.D.5    Gu, Y.Y.6
  • 29
    • 78649830454 scopus 로고    scopus 로고
    • Genetic susceptibility to systemic lupus erythematosus in the genomic era
    • Deng Y., Tsao B.P. Genetic susceptibility to systemic lupus erythematosus in the genomic era. Nat. Rev. Rheumatol. 2010, 6:683-692.
    • (2010) Nat. Rev. Rheumatol. , vol.6 , pp. 683-692
    • Deng, Y.1    Tsao, B.P.2
  • 30
    • 44849087740 scopus 로고    scopus 로고
    • Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients
    • Sawalha A.H., Jeffries M., Webb R., Lu Q., Gorelik G., Ray D., Osban J., Knowlton N., Johnson K., Richardson B. Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients. Genes. Immun. 2008, 9:368-378.
    • (2008) Genes. Immun. , vol.9 , pp. 368-378
    • Sawalha, A.H.1    Jeffries, M.2    Webb, R.3    Lu, Q.4    Gorelik, G.5    Ray, D.6    Osban, J.7    Knowlton, N.8    Johnson, K.9    Richardson, B.10
  • 31
    • 18644384042 scopus 로고    scopus 로고
    • Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease
    • Kirou K.A., Lee C., George S., Louca K., Peterson M.G., Crow M.K. Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease. Arthritis Rheum. 2005, 52:1491-1503.
    • (2005) Arthritis Rheum. , vol.52 , pp. 1491-1503
    • Kirou, K.A.1    Lee, C.2    George, S.3    Louca, K.4    Peterson, M.G.5    Crow, M.K.6
  • 33
    • 84860328972 scopus 로고    scopus 로고
    • The interferon-regulated gene signature is elevated in subacute cutaneous lupus erythematosus and discoid lupus erythematosus and correlates with the cutaneous lupus area and severity index score
    • Braunstein I., Klein R., Okawa J., Werth V.P. The interferon-regulated gene signature is elevated in subacute cutaneous lupus erythematosus and discoid lupus erythematosus and correlates with the cutaneous lupus area and severity index score. Br. J. Dermatol. 2012, 166:971-975.
    • (2012) Br. J. Dermatol. , vol.166 , pp. 971-975
    • Braunstein, I.1    Klein, R.2    Okawa, J.3    Werth, V.P.4
  • 34
    • 0344665750 scopus 로고    scopus 로고
    • Microarray analysis of interferon-regulated genes in SLE
    • Crow M.K., Kirou K.A., Wohlgemuth J. Microarray analysis of interferon-regulated genes in SLE. Autoimmunity 2003, 36:481-490.
    • (2003) Autoimmunity , vol.36 , pp. 481-490
    • Crow, M.K.1    Kirou, K.A.2    Wohlgemuth, J.3
  • 35
    • 44849085476 scopus 로고    scopus 로고
    • The innate immune system in SLE: type I interferons and dendritic cells
    • Ronnblom L., Pascual V. The innate immune system in SLE: type I interferons and dendritic cells. Lupus 2008, 17:394-399.
    • (2008) Lupus , vol.17 , pp. 394-399
    • Ronnblom, L.1    Pascual, V.2
  • 36
    • 33749429975 scopus 로고    scopus 로고
    • Type-I interferons and systemic lupus erythematosus
    • Koutouzov S., Mathian A., Dalloul A. Type-I interferons and systemic lupus erythematosus. Autoimmun. Rev. 2006, 5:554-562.
    • (2006) Autoimmun. Rev. , vol.5 , pp. 554-562
    • Koutouzov, S.1    Mathian, A.2    Dalloul, A.3
  • 37
    • 79957541792 scopus 로고    scopus 로고
    • Meta-analysis of microarray data using a pathway-based approach identifies a 37-gene expression signature for systemic lupus erythematosus in human peripheral blood mononuclear cells
    • Arasappan D., Tong W., Mummaneni P., Fang H., Amur S. Meta-analysis of microarray data using a pathway-based approach identifies a 37-gene expression signature for systemic lupus erythematosus in human peripheral blood mononuclear cells. BMC Med. 2011, 9:65.
    • (2011) BMC Med. , vol.9 , pp. 65
    • Arasappan, D.1    Tong, W.2    Mummaneni, P.3    Fang, H.4    Amur, S.5
  • 39
    • 84856022097 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes
    • Santer D.M., Wiedeman A.E., Teal T.H., Ghosh P., Elkon K.B. Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes. J. Immunol. 2012, 188:902-915.
    • (2012) J. Immunol. , vol.188 , pp. 902-915
    • Santer, D.M.1    Wiedeman, A.E.2    Teal, T.H.3    Ghosh, P.4    Elkon, K.B.5
  • 41
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman R.M. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 1991, 9:271-296.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 271-296
    • Steinman, R.M.1
  • 42
    • 84883114740 scopus 로고    scopus 로고
    • Immunopathogenic mechanisms of systemic autoimmune disease
    • Wahren-Herlenius M., Dorner T. Immunopathogenic mechanisms of systemic autoimmune disease. Lancet 2013, 382:819-831.
    • (2013) Lancet , vol.382 , pp. 819-831
    • Wahren-Herlenius, M.1    Dorner, T.2
  • 43
    • 84884222695 scopus 로고    scopus 로고
    • Systemic lupus erythematosus immune complexes increase the expression of SLAM family members CD319 (CRACC) and CD229 (LY-9) on plasmacytoid dendritic cells and CD319 on CD56dim NK cells
    • Hagberg N., Theorell J., Schlums H., Eloranta M.L., Bryceson Y.T., Ronnblom L. Systemic lupus erythematosus immune complexes increase the expression of SLAM family members CD319 (CRACC) and CD229 (LY-9) on plasmacytoid dendritic cells and CD319 on CD56dim NK cells. J. Immunol. 2013, 191:2989-2998.
    • (2013) J. Immunol. , vol.191 , pp. 2989-2998
    • Hagberg, N.1    Theorell, J.2    Schlums, H.3    Eloranta, M.L.4    Bryceson, Y.T.5    Ronnblom, L.6
  • 44
    • 0035403969 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions
    • Farkas L., Beiske K., Lund-Johansen F., Brandtzaeg P., Jahnsen F.L. Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions. Am. J. Pathol. 2001, 159:237-243.
    • (2001) Am. J. Pathol. , vol.159 , pp. 237-243
    • Farkas, L.1    Beiske, K.2    Lund-Johansen, F.3    Brandtzaeg, P.4    Jahnsen, F.L.5
  • 46
    • 82955233986 scopus 로고    scopus 로고
    • Neutrophils in the pathogenesis and manifestations of SLE
    • Kaplan M.J. Neutrophils in the pathogenesis and manifestations of SLE. Nat. Rev. Rheumatol. 2011, 7:691-699.
    • (2011) Nat. Rev. Rheumatol. , vol.7 , pp. 691-699
    • Kaplan, M.J.1
  • 48
    • 77955343903 scopus 로고    scopus 로고
    • Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice
    • Scapini P., Hu Y., Chu C.L., Migone T.S., Defranco A.L., Cassatella M.A., Lowell C.A. Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice. J. Exp. Med. 2010, 207:1757-1773.
    • (2010) J. Exp. Med. , vol.207 , pp. 1757-1773
    • Scapini, P.1    Hu, Y.2    Chu, C.L.3    Migone, T.S.4    Defranco, A.L.5    Cassatella, M.A.6    Lowell, C.A.7
  • 49
    • 34247121966 scopus 로고    scopus 로고
    • Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches
    • Wenzel J., Tuting T. Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches. Exp. Dermatol. 2007, 16:454-463.
    • (2007) Exp. Dermatol. , vol.16 , pp. 454-463
    • Wenzel, J.1    Tuting, T.2
  • 51
    • 0033105359 scopus 로고    scopus 로고
    • Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes
    • Saeki H., Moore A.M., Brown M.J., Hwang S.T. Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes. J. Immunol. 1999, 162:2472-2475.
    • (1999) J. Immunol. , vol.162 , pp. 2472-2475
    • Saeki, H.1    Moore, A.M.2    Brown, M.J.3    Hwang, S.T.4
  • 54
    • 27444447430 scopus 로고    scopus 로고
    • Differential effect of IL10 and TNF{alpha} genotypes on determining susceptibility to discoid and systemic lupus erythematosus
    • Suarez A., Lopez P., Mozo L., Gutierrez C. Differential effect of IL10 and TNF{alpha} genotypes on determining susceptibility to discoid and systemic lupus erythematosus. Ann. Rheum. Dis. 2005, 64:1605-1610.
    • (2005) Ann. Rheum. Dis. , vol.64 , pp. 1605-1610
    • Suarez, A.1    Lopez, P.2    Mozo, L.3    Gutierrez, C.4
  • 58
    • 84877926859 scopus 로고    scopus 로고
    • Cutaneous lupus erythematosus: clinical aspects and molecular pathogenesis
    • Oke V., Wahren-Herlenius M. Cutaneous lupus erythematosus: clinical aspects and molecular pathogenesis. J. Intern. Med. 2013, 273:544-554.
    • (2013) J. Intern. Med. , vol.273 , pp. 544-554
    • Oke, V.1    Wahren-Herlenius, M.2
  • 61
    • 0031127607 scopus 로고    scopus 로고
    • The influence of ultraviolet light on immunological cytotoxicity in the skin
    • Norris D.A., Whang K., David-Bajar K., Bennion S.D. The influence of ultraviolet light on immunological cytotoxicity in the skin. Photochem. Photobiol. 1997, 65:636-646.
    • (1997) Photochem. Photobiol. , vol.65 , pp. 636-646
    • Norris, D.A.1    Whang, K.2    David-Bajar, K.3    Bennion, S.D.4
  • 62
    • 1542299285 scopus 로고    scopus 로고
    • Induction of apoptosis in monocytes and lymphocytes by serum from patients with systemic lupus erythematosus-an additional mechanism to increased autoantigen load?
    • Bengtsson A.A., Sturfelt G., Gullstrand B., Truedsson L. Induction of apoptosis in monocytes and lymphocytes by serum from patients with systemic lupus erythematosus-an additional mechanism to increased autoantigen load?. Clin. Exp. Immunol. 2004, 135:535-543.
    • (2004) Clin. Exp. Immunol. , vol.135 , pp. 535-543
    • Bengtsson, A.A.1    Sturfelt, G.2    Gullstrand, B.3    Truedsson, L.4
  • 64
    • 58149161860 scopus 로고    scopus 로고
    • Type I interferon-associated cytotoxic inflammation in cutaneous lupus erythematosus
    • Wenzel J., Zahn S., Bieber T., Tuting T. Type I interferon-associated cytotoxic inflammation in cutaneous lupus erythematosus. Arch. Dermatol. Res. 2009, 301:83-86.
    • (2009) Arch. Dermatol. Res. , vol.301 , pp. 83-86
    • Wenzel, J.1    Zahn, S.2    Bieber, T.3    Tuting, T.4
  • 65
    • 0033081259 scopus 로고    scopus 로고
    • Type I interferons keep activated T cells alive
    • Marrack P., Kappler J., Mitchell T. Type I interferons keep activated T cells alive. J. Exp. Med. 1999, 189:521-530.
    • (1999) J. Exp. Med. , vol.189 , pp. 521-530
    • Marrack, P.1    Kappler, J.2    Mitchell, T.3
  • 66
    • 0021968045 scopus 로고
    • Stimulation of in vitro immunoglobulin production by interferon-alpha
    • Neubauer R.H., Goldstein L., Rabin H., Stebbing N. Stimulation of in vitro immunoglobulin production by interferon-alpha. J. Immunol. 1985, 134:299-304.
    • (1985) J. Immunol. , vol.134 , pp. 299-304
    • Neubauer, R.H.1    Goldstein, L.2    Rabin, H.3    Stebbing, N.4
  • 68
    • 34548438559 scopus 로고    scopus 로고
    • High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus
    • Niewold T.B., Hua J., Lehman T.J., Harley J.B., Crow M.K. High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus. Genes Immun. 2007, 8:492-502.
    • (2007) Genes Immun. , vol.8 , pp. 492-502
    • Niewold, T.B.1    Hua, J.2    Lehman, T.J.3    Harley, J.B.4    Crow, M.K.5
  • 69
    • 51849117301 scopus 로고    scopus 로고
    • The PTPN22 C1858T polymorphism is associated with skewing of cytokine profiles toward high interferon-alpha activity and low tumor necrosis factor alpha levels in patients with lupus
    • Kariuki S.N., Crow M.K., Niewold T.B. The PTPN22 C1858T polymorphism is associated with skewing of cytokine profiles toward high interferon-alpha activity and low tumor necrosis factor alpha levels in patients with lupus. Arthritis Rheum. 2008, 58:2818-2823.
    • (2008) Arthritis Rheum. , vol.58 , pp. 2818-2823
    • Kariuki, S.N.1    Crow, M.K.2    Niewold, T.B.3
  • 78
    • 34548483908 scopus 로고    scopus 로고
    • SUMO-specific proteases: a twist in the tail
    • Hay R.T. SUMO-specific proteases: a twist in the tail. Trends Cell Biol. 2007, 17:370-376.
    • (2007) Trends Cell Biol. , vol.17 , pp. 370-376
    • Hay, R.T.1
  • 81
    • 84889686155 scopus 로고    scopus 로고
    • Genome-wide expression analysis suggests unique disease-promoting and disease-preventing signatures in Pemphigus vulgaris
    • Dey-Rao R., Seiffert-Sinha K., Sinha A.A. Genome-wide expression analysis suggests unique disease-promoting and disease-preventing signatures in Pemphigus vulgaris. Genes Immun. 2013, 14:487-499.
    • (2013) Genes Immun. , vol.14 , pp. 487-499
    • Dey-Rao, R.1    Seiffert-Sinha, K.2    Sinha, A.A.3
  • 82
    • 84862756451 scopus 로고    scopus 로고
    • Global transcriptional analysis of psoriatic skin and blood confirms known disease-associated pathways and highlights novel genomic "hot spots" for differentially expressed genes
    • Coda A.B., Icen M., Smith J.R., Sinha A.A. Global transcriptional analysis of psoriatic skin and blood confirms known disease-associated pathways and highlights novel genomic "hot spots" for differentially expressed genes. Genomics 2012, 100:18-26.
    • (2012) Genomics , vol.100 , pp. 18-26
    • Coda, A.B.1    Icen, M.2    Smith, J.R.3    Sinha, A.A.4
  • 83
    • 1842507530 scopus 로고    scopus 로고
    • Degrees of differential gene expression: detecting biologically significant expression differences and estimating their magnitudes
    • Bickel D.R. Degrees of differential gene expression: detecting biologically significant expression differences and estimating their magnitudes. Bioinformatics 2004, 20:682-688.
    • (2004) Bioinformatics , vol.20 , pp. 682-688
    • Bickel, D.R.1
  • 85
    • 79952051920 scopus 로고    scopus 로고
    • Assessing quality and completeness of human transcriptional regulatory pathways on a genome-wide scale
    • Shmelkov E., Tang Z., Aifantis I., Statnikov A. Assessing quality and completeness of human transcriptional regulatory pathways on a genome-wide scale. Biol. Direct 2011, 6:15.
    • (2011) Biol. Direct , vol.6 , pp. 15
    • Shmelkov, E.1    Tang, Z.2    Aifantis, I.3    Statnikov, A.4
  • 90
    • 78249257797 scopus 로고    scopus 로고
    • Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus
    • Clancy R.M., Marion M.C., Kaufman K.M., Ramos P.S., Adler A., Harley J.B., Langefeld C.D., Buyon J.P. Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus. Arthritis Rheum. 2010, 62:3415-3424.
    • (2010) Arthritis Rheum. , vol.62 , pp. 3415-3424
    • Clancy, R.M.1    Marion, M.C.2    Kaufman, K.M.3    Ramos, P.S.4    Adler, A.5    Harley, J.B.6    Langefeld, C.D.7    Buyon, J.P.8
  • 96
    • 35748936771 scopus 로고    scopus 로고
    • A genome-wide study of lupus: preliminary analysis and data release
    • Cervino A.C., Tsinoremas N.F., Hoffman R.W. A genome-wide study of lupus: preliminary analysis and data release. Ann. N. Y. Acad. Sci. 2007, 1110:131-139.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1110 , pp. 131-139
    • Cervino, A.C.1    Tsinoremas, N.F.2    Hoffman, R.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.