메뉴 건너뛰기




Volumn 38, Issue 9, 2011, Pages 839-849

Recent advances in cytokines in cutaneous and systemic lupus erythematosus

Author keywords

cutaneous lupus erythematosus; cytokine; erythematosus; systemic lupus

Indexed keywords

ALPHA INTERFERON; AMG 811; ANTIMALARIAL AGENT; AUTOANTIBODY; CHLOROQUINE; CYTOKINE; CYTOKINE RECEPTOR; ETANERCEPT; GAMMA INTERFERON; HYDROXYCHLOROQUINE; INFLIXIMAB; INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 23; INTERLEUKIN 6; MONOCLONAL ANTIBODY; RONTALIZUMAB; SIFALIMUMAB; TOCILIZUMAB; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 80052057054     PISSN: 03852407     EISSN: 13468138     Source Type: Journal    
DOI: 10.1111/j.1346-8138.2011.01237.x     Document Type: Review
Times cited : (44)

References (105)
  • 2
    • 76349107593 scopus 로고    scopus 로고
    • Pathogenesis of human systemic lupus erythematosus: Recent advances
    • Crispín JC, Liossis SN, Kis-Toth K, et al. Pathogenesis of human systemic lupus erythematosus: recent advances. Trends Mol Med 2010; 16: 47-57.
    • (2010) Trends Mol Med , vol.16 , pp. 47-57
    • Crispín, J.C.1    Liossis, S.N.2    Kis-Toth, K.3
  • 3
    • 65649148625 scopus 로고    scopus 로고
    • Cytokines in systemic lupus erythematosus
    • Elaine VL, Antonio LC,. Cytokines in systemic lupus erythematosus. Curr Mol Med 2009; 9: 242-254.
    • (2009) Curr Mol Med , vol.9 , pp. 242-254
    • Elaine, V.L.1    Antonio, L.C.2
  • 4
    • 77952509491 scopus 로고    scopus 로고
    • Cytokine networks in systemic lupus erythematosus
    • Published online: 15 April 2010; doi.
    • Lee HM, Sugino H, Nishimoto N,. Cytokine networks in systemic lupus erythematosus. J Biomed Biotechnol Published online: 15 April 2010; doi:.
    • J Biomed Biotechnol
    • Lee, H.M.1    Sugino, H.2    Nishimoto, N.3
  • 5
    • 67849099131 scopus 로고    scopus 로고
    • Recent insights into the genetic basis of systemic lupus erythematosus
    • Moser KL, Kelly JA, Lessard CJ, Harley JB,. Recent insights into the genetic basis of systemic lupus erythematosus. Genes Immun 2009; 10: 373-379.
    • (2009) Genes Immun , vol.10 , pp. 373-379
    • Moser, K.L.1    Kelly, J.A.2    Lessard, C.J.3    Harley, J.B.4
  • 6
    • 66149083275 scopus 로고    scopus 로고
    • Review of recent genome-wide association scans in lupus
    • Graham RR, Hom G, Ortmann W, Behrens TW,. Review of recent genome-wide association scans in lupus. J Intern Med 2009; 265: 680-688.
    • (2009) J Intern Med , vol.265 , pp. 680-688
    • Graham, R.R.1    Hom, G.2    Ortmann, W.3    Behrens, T.W.4
  • 7
    • 77953555514 scopus 로고    scopus 로고
    • Cytokines as therapeutic targets in SLE
    • Rönnblom L, Elkon KB,. Cytokines as therapeutic targets in SLE. Nat Rev Rheumatol 2010; 6: 339-347.
    • (2010) Nat Rev Rheumatol , vol.6 , pp. 339-347
    • Rönnblom, L.1    Elkon, K.B.2
  • 8
    • 77955533864 scopus 로고    scopus 로고
    • Overview of common, rare and atypical manifestations of cutaneous lupus erythematosus and histopathological correlates
    • Obermoser G, Sontheimer RD, Zelger B,. Overview of common, rare and atypical manifestations of cutaneous lupus erythematosus and histopathological correlates. Lupus 2010; 19: 1050-1070.
    • (2010) Lupus , vol.19 , pp. 1050-1070
    • Obermoser, G.1    Sontheimer, R.D.2    Zelger, B.3
  • 9
    • 65549168110 scopus 로고    scopus 로고
    • Classification of lupus erythematosus based upon Japanese patients
    • Tsuchida T,. Classification of lupus erythematosus based upon Japanese patients. Autoimmun Rev 2009; 8: 453-455.
    • (2009) Autoimmun Rev , vol.8 , pp. 453-455
    • Tsuchida, T.1
  • 11
    • 44849084204 scopus 로고    scopus 로고
    • Pathogenesis of cutaneous lupus erythematosus
    • DOI 10.1177/0961203308090019, Proceedings of the 7th european Lupus Meeting
    • Kuhn A, Bijl M,. Pathogenesis of cutaneous lupus erythematosus. Lupus 2008; 17: 389-393. (Pubitemid 351798714)
    • (2008) Lupus , vol.17 , Issue.5 SPEC. ISSUE , pp. 389-393
    • Kuhn, A.1    Bijl, M.2
  • 12
    • 77955525721 scopus 로고    scopus 로고
    • Cutaneous lupus erythematosus: Recent lessons from animal models
    • Ghoreishi M, Dutz JP,. Cutaneous lupus erythematosus: recent lessons from animal models. Lupus 2010; 19: 1029-1035.
    • (2010) Lupus , vol.19 , pp. 1029-1035
    • Ghoreishi, M.1    Dutz, J.P.2
  • 13
    • 77955541911 scopus 로고    scopus 로고
    • Pathogenesis of cutaneous lupus erythematosus: Common and different features in distinct subsets
    • Wenzel J, Zahn S, Tüting T,. Pathogenesis of cutaneous lupus erythematosus: common and different features in distinct subsets. Lupus 2010; 19: 1020-1028.
    • (2010) Lupus , vol.19 , pp. 1020-1028
    • Wenzel, J.1    Zahn, S.2    Tüting, T.3
  • 14
    • 78651414618 scopus 로고    scopus 로고
    • Overview of the biology of type i interferons
    • Kalliolias GD, Ivashkiv LB,. Overview of the biology of type I interferons. Arthritis Res Ther 2010; 12 (Suppl. 1): S1.
    • (2010) Arthritis Res Ther , vol.12 , Issue.SUPPL. 1
    • Kalliolias, G.D.1    Ivashkiv, L.B.2
  • 15
    • 44849085476 scopus 로고    scopus 로고
    • The innate immune system in SLE: Type I interferons and dendritic cells
    • DOI 10.1177/0961203308090020, Proceedings of the 7th european Lupus Meeting
    • Rönnblom L, Pascual V,. The innate immune system in SLE: type I interferons and dendritic cells. Lupus 2008; 17: 394-399. (Pubitemid 351798715)
    • (2008) Lupus , vol.17 , Issue.5 SPEC. ISSUE , pp. 394-399
    • Ronnblom, L.1    Pascual, V.2
  • 16
    • 33749429975 scopus 로고    scopus 로고
    • Type-I interferons and systemic lupus erythematosus
    • DOI 10.1016/j.autrev.2006.05.002, PII S1568997206000796
    • Koutouzov S, Mathian A, Dalloul A,. Type-I interferons and systemic lupus erythematosus. Autoimmun Rev 2006; 5: 554-562. (Pubitemid 44508854)
    • (2006) Autoimmunity Reviews , vol.5 , Issue.8 , pp. 554-562
    • Koutouzov, S.1    Mathian, A.2    Dalloul, A.3
  • 18
    • 65249143322 scopus 로고    scopus 로고
    • Interferon-alpha treatment of female (NZW x BXSB)F(1) mice mimics some but not all features associated with the Yaa mutation
    • Ramanujam M, Kahn P, Huang W, et al. Interferon-alpha treatment of female (NZW x BXSB)F(1) mice mimics some but not all features associated with the Yaa mutation. Arthritis Rheum 2009; 60: 1096-1101.
    • (2009) Arthritis Rheum , vol.60 , pp. 1096-1101
    • Ramanujam, M.1    Kahn, P.2    Huang, W.3
  • 20
    • 3242805826 scopus 로고    scopus 로고
    • Type I IFN protects against murine lupus
    • Hron JD, Peng SL,. Type I IFN protects against murine lupus. J Immunol 2004; 173: 2134-2142. (Pubitemid 38971652)
    • (2004) Journal of Immunology , vol.173 , Issue.3 , pp. 2134-2142
    • Hron, J.D.1    Peng, S.L.2
  • 21
    • 0018775078 scopus 로고
    • Immune interferon in the circulation of patients with autoimmune disease
    • Hooks JJ, Moutsopoulos HM, Geis SA, Stahl NI, Decker JL, Notkins AL,. Immune interferon in the circulation of patients with autoimmune disease. N Engl J Med 1979; 301: 5-8. (Pubitemid 9226519)
    • (1979) New England Journal of Medicine , vol.301 , Issue.1 , pp. 5-8
    • Hooks, J.J.1    Moutsopoulos, H.M.2    Geis, S.A.3
  • 24
    • 0344665750 scopus 로고    scopus 로고
    • Microarray analysis of interferon-regulated genes in SLE
    • DOI 10.1080/08916930310001625952
    • Crow MK, Kirou KA, Wohlgemuth J,. Microarray analysis of interferon-regulated genes in SLE. Autoimmunity 2003; 36: 481-490. (Pubitemid 37498244)
    • (2003) Autoimmunity , vol.36 , Issue.8 , pp. 481-490
    • Crow, M.K.1    Kirou, K.A.2    Wohlgemuth, J.3
  • 25
    • 0345359586 scopus 로고    scopus 로고
    • Induction of clinical autoimmune disease by therapeutic interferon-α
    • DOI 10.1080/08916930310001605873
    • Gota C, Calabrese L,. Induction of clinical autoimmune disease by therapeutic interferon-alpha. Autoimmunity 2003; 36: 511-518. (Pubitemid 37498247)
    • (2003) Autoimmunity , vol.36 , Issue.8 , pp. 511-518
    • Gota, C.1    Calabrese, L.2
  • 26
    • 70449532495 scopus 로고    scopus 로고
    • Interferons and autoimmune disorders
    • Meyer O,. Interferons and autoimmune disorders. Joint Bone Spine 2009; 76: 464-473.
    • (2009) Joint Bone Spine , vol.76 , pp. 464-473
    • Meyer, O.1
  • 27
    • 66449097622 scopus 로고    scopus 로고
    • Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase i trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus
    • Yao Y, Richman L, Higgs BW, et al. Neutralization of interferon-alpha/ beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus. Arthritis Rheum 2009; 60: 1785-1796.
    • (2009) Arthritis Rheum , vol.60 , pp. 1785-1796
    • Yao, Y.1    Richman, L.2    Higgs, B.W.3
  • 28
    • 79956263705 scopus 로고    scopus 로고
    • Use of type i interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNalpha antibody, in systemic lupus erythematosus
    • Yao Y, Higgs BW, Richman L, White B, Jallal B,. Use of type I interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNalpha antibody, in systemic lupus erythematosus. Arthritis Res Ther 2010; 12 (Suppl 1): S6.
    • (2010) Arthritis Res Ther , vol.12 , Issue.SUPPL. 1
    • Yao, Y.1    Higgs, B.W.2    Richman, L.3    White, B.4    Jallal, B.5
  • 29
    • 77953603329 scopus 로고    scopus 로고
    • Dose-dependent modulation of interferon regulated genes with administration of single and repeat doses of Rontalizumab in a phase I, placebo controlled, double blind, dose escalation study in SLE
    • : (abstract 2072).
    • McBride JM, Wallace DJ, Yao Z, et al. Dose-dependent modulation of interferon regulated genes with administration of single and repeat doses of Rontalizumab in a phase I, placebo controlled, double blind, dose escalation study in SLE. Arthritis Rheum 2009; 60: S775-S776 (abstract 2072).
    • (2009) Arthritis Rheum , vol.60
    • McBride, J.M.1    Wallace, D.J.2    Yao, Z.3
  • 30
    • 44849117329 scopus 로고    scopus 로고
    • MEDI-545, an anti-interferon alpha monoclonal antibody, shows evidence of clinical activity in systemic lupus erythematous
    • : (abstract 1325).
    • Wallace DJ, Petri M, Olsen N, et al. MEDI-545, an anti-interferon alpha monoclonal antibody, shows evidence of clinical activity in systemic lupus erythematous. Arthritis Rheum 2007; 56: S526-S527 (abstract 1325).
    • (2007) Arthritis Rheum , vol.56
    • Wallace, D.J.1    Petri, M.2    Olsen, N.3
  • 31
    • 58149161860 scopus 로고    scopus 로고
    • Type i interferon-associated cytotoxic inflammation in cutaneous lupus erythematosus
    • Wenzel J, Zahn S, Bieber T, Tüting T,. Type I interferon-associated cytotoxic inflammation in cutaneous lupus erythematosus. Arch Dermatol Res 2009; 301: 83-86.
    • (2009) Arch Dermatol Res , vol.301 , pp. 83-86
    • Wenzel, J.1    Zahn, S.2    Bieber, T.3    Tüting, T.4
  • 32
    • 34247121966 scopus 로고    scopus 로고
    • Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches
    • DOI 10.1111/j.1600-0625.2007.00556.x
    • Wenzel J, Tüting T,. Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches. Exp Dermatol 2007; 16: 454-463. (Pubitemid 46585374)
    • (2007) Experimental Dermatology , vol.16 , Issue.5 , pp. 454-463
    • Wenzel, J.1    Tuting, T.2
  • 33
    • 0028896631 scopus 로고
    • Expression of MxA protein in inflammatory dermatoses
    • Fäh J, Pavlovic J, Burg G,. Expression of MxA protein in inflammatory dermatoses. J Histochem Cytochem 1995; 43: 47-52.
    • (1995) J Histochem Cytochem , vol.43 , pp. 47-52
    • Fäh, J.1    Pavlovic, J.2    Burg, G.3
  • 34
    • 14944346758 scopus 로고    scopus 로고
    • Enhanced type I interferon signalling promotes Th1-biased inflammation in cutaneous lupus erythematosus
    • DOI 10.1002/path.1721
    • Wenzel J, Wörenkämper E, Freutel S, et al. Enhanced type I interferon signalling promotes Th1-biased inflammation in cutaneous lupus erythematosus. J Pathol 2005; 205: 435-442. (Pubitemid 40361331)
    • (2005) Journal of Pathology , vol.205 , Issue.4 , pp. 435-442
    • Wenzel, J.1    Worenkamper, E.2    Freutel, S.3    Henze, S.4    Haller, O.5    Bieber, T.6    Tuting, T.7
  • 35
    • 0035403969 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells (natural interferon-α/β-producing cells) accumulate in cutaneous lupus erythematosus lesions
    • Farkas L, Beiske K, Lund-Johansen F, Brandtzaeg P, Jahnsen FL,. Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions. Am J Pathol 2001; 159: 237-243. (Pubitemid 33704208)
    • (2001) American Journal of Pathology , vol.159 , Issue.1 , pp. 237-243
    • Farkas, L.1    Beiske, K.2    Lund-Johansen, F.3    Brandtzaeg, P.4    Jahnsen, F.L.5
  • 36
    • 34548585456 scopus 로고    scopus 로고
    • The expression pattern of interferon-inducible proteins reflects the characteristic histological distribution of infiltrating immune cells in different cutaneous lupus erythematosus subsets
    • DOI 10.1111/j.1365-2133.2007.08137.x
    • Wenzel J, Zahn S, Mikus S, Wiechert A, Bieber T, Tüting T,. The expression pattern of interferon-inducible proteins reflects the characteristic histological distribution of infiltrating immune cells in different cutaneous lupus erythematosus subsets. Br J Dermatol 2007; 157: 752-757. (Pubitemid 47389912)
    • (2007) British Journal of Dermatology , vol.157 , Issue.4 , pp. 752-757
    • Wenzel, J.1    Zahn, S.2    Mikus, S.3    Wiechert, A.4    Bieber, T.5    Tuting, T.6
  • 37
    • 33745030751 scopus 로고    scopus 로고
    • Induction of interferon-α by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome auto antigen - Associated RNA
    • DOI 10.1002/art.21893
    • Lövgren T, Eloranta ML, Kastner B, Wahren-Herlenius M, Alm GV, Rönnblom L,. Induction of interferon-alpha by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA. Arthritis Rheum 2006; 54: 1917-1927. (Pubitemid 43877941)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.6 , pp. 1917-1927
    • Lovgren, T.1    Eloranta, M.-L.2    Kastner, B.3    Wahren-Herlenius, M.4    Alm, G.V.5    Ronnblom, L.6
  • 38
    • 78650261558 scopus 로고    scopus 로고
    • Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFN lambda) in cutaneous lupus erythematosus
    • Zahn S, Rehkämper C, Kümmerer BM, et al. Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFN lambda) in cutaneous lupus erythematosus. J Invest Dermatol 2011; 131: 133-140.
    • (2011) J Invest Dermatol , vol.131 , pp. 133-140
    • Zahn, S.1    Rehkämper, C.2    Kümmerer, B.M.3
  • 39
    • 0023571873 scopus 로고
    • 1 lupus-like nephritis with monoclonal antibody to γ interferon
    • DOI 10.1084/jem.166.3.798
    • Jacob CO, Van der Meide PH, McDevitt HO,. In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon. J Exp Med 1987; 166: 798-803. (Pubitemid 18013554)
    • (1987) Journal of Experimental Medicine , vol.166 , Issue.3 , pp. 798-803
    • Jacob, C.O.1    Van Der Meide, P.H.2    McDevitt, H.O.3
  • 40
    • 0032522778 scopus 로고    scopus 로고
    • 1 mice
    • Haas C, Ryffel B, Le Hir M,. IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice. J Immunol 1998; 160: 3713-3718. (Pubitemid 28176072)
    • (1998) Journal of Immunology , vol.160 , Issue.8 , pp. 3713-3718
    • Haas, C.1    Ryffel, B.2    Le Hir, M.3
  • 41
    • 0032518439 scopus 로고    scopus 로고
    • Interferon-γ is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice
    • Balomenos D, Rumold R, Theofilopoulos AN,. Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice. J Clin Invest 1998; 101: 364-371. (Pubitemid 28067333)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.2 , pp. 364-371
    • Balomenos, D.1    Rumold, R.2    Theofilopoulos, A.N.3
  • 42
    • 0030702821 scopus 로고    scopus 로고
    • Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon γ in the epidermis
    • DOI 10.1084/jem.186.9.1451
    • Seery JP, Carroll JM, Cattell V, Watt FM,. Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon gamma in the epidermis. J Exp Med 1997; 186: 1451-1459. (Pubitemid 27479804)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.9 , pp. 1451-1459
    • Seery, J.P.1    Carroll, J.M.2    Cattell, V.3    Watt, F.M.4
  • 43
    • 0027513607 scopus 로고
    • Cytokine profile in systemic lupus erythematosus, rheumatoid arthritis, and other rheumatic diseases
    • DOI 10.1007/BF00920636
    • al-Janadi M, al-Balla S, al-Dalaan A, Raziuddin S,. Cytokine profile in systemic lupus erythematosus, rheumatoid arthritis, and other rheumatic diseases. J Clin Immunol 1993; 13: 58-67. (Pubitemid 23047997)
    • (1993) Journal of Clinical Immunology , vol.13 , Issue.1 , pp. 58-67
    • Al-Janadi, M.1    Al-Balla, S.2    Al-Dalaan, A.3    Raziuddin, S.4
  • 45
    • 26244435934 scopus 로고    scopus 로고
    • Th1 cytokines in the pathogenesis of lupus nephritis: The role of IL-18
    • DOI 10.1016/j.autrev.2005.04.009, PII S1568997205000613
    • Calvani N, Tucci M, Richards HB, Tartaglia P, Silvestris F,. Th1 cytokines in the pathogenesis of lupus nephritis: the role of IL-18. Autoimmun Rev 2005; 4: 542-548. (Pubitemid 41415767)
    • (2005) Autoimmunity Reviews , vol.4 , Issue.8 , pp. 542-548
    • Calvani, N.1    Tucci, M.2    Richards, H.B.3    Tartaglia, P.4    Silvestris, F.5
  • 46
    • 49649119208 scopus 로고    scopus 로고
    • Excessive production of IFN-gamma in patients with systemic lupus erythematosus and its contribution to induction of B lymphocyte stimulator/B cell-activating factor/TNF ligand superfamily-13B
    • Harigai M, Kawamoto M, Hara M, Kubota T, Kamatani N, Miyasaka N,. Excessive production of IFN-gamma in patients with systemic lupus erythematosus and its contribution to induction of B lymphocyte stimulator/B cell-activating factor/TNF ligand superfamily-13B. J Immunol 2008; 181: 2211-2219.
    • (2008) J Immunol , vol.181 , pp. 2211-2219
    • Harigai, M.1    Kawamoto, M.2    Hara, M.3    Kubota, T.4    Kamatani, N.5    Miyasaka, N.6
  • 47
  • 48
    • 0033111409 scopus 로고    scopus 로고
    • New pieces to the SLE cytokine puzzle
    • Kirou KA, Crow MK,. New pieces to the SLE cytokine puzzle. Clin Immunol 1999; 91: 1-5.
    • (1999) Clin Immunol , vol.91 , pp. 1-5
    • Kirou, K.A.1    Crow, M.K.2
  • 49
    • 2142650265 scopus 로고    scopus 로고
    • Susceptibility of T cell receptor-α chain knock-out mice to ultraviolet B light and fluorouracil: A novel model for drug-induced cutaneous lupus erythematosus
    • DOI 10.1111/j.1365-2249.2004.02458.x
    • Yoshimasu T, Nishide T, Seo N, et al. Susceptibility of T cell receptor-alpha chain knock-out mice to ultraviolet B light and fluorouracil: a novel model for drug-induced cutaneous lupus erythematosus. Clin Exp Immunol 2004; 136: 245-254. (Pubitemid 38543442)
    • (2004) Clinical and Experimental Immunology , vol.136 , Issue.2 , pp. 245-254
    • Yoshimasu, T.1    Nishide, T.2    Seo, N.3    Hiroi, A.4    Ohtani, T.5    Uede, K.6    Furukawa, F.7
  • 52
    • 0023874728 scopus 로고
    • Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis
    • DOI 10.1038/331356a0
    • Jacob CO, McDevitt HO,. Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis. Nature 1988; 331: 356-358. (Pubitemid 18042493)
    • (1988) Nature , vol.331 , Issue.6154 , pp. 356-358
    • Jacob, C.O.1    McDevitt, H.O.2
  • 53
    • 0028954960 scopus 로고
    • Biphasic increase in circulating and renal TNF-alpha in MRL-lpr mice with differing regulatory mechanisms
    • Yokoyama H, Kreft B, Kelley VR,. Biphasic increase in circulating and renal TNF-alpha in MRL-lpr mice with differing regulatory mechanisms. Kidney Int 1995; 47: 122-130.
    • (1995) Kidney Int , vol.47 , pp. 122-130
    • Yokoyama, H.1    Kreft, B.2    Kelley, V.R.3
  • 54
    • 47049112010 scopus 로고    scopus 로고
    • The role of tumor necrosis factor-alpha in systemic lupus erythematosus
    • Published online: 23 January 2008; doi.
    • Aringer M, Smolen JS,. The role of tumor necrosis factor-alpha in systemic lupus erythematosus. Arthritis Res Ther. Published online: 23 January 2008; doi:.
    • Arthritis Res Ther
    • Aringer, M.1    Smolen, J.S.2
  • 55
    • 33846231376 scopus 로고    scopus 로고
    • Effects of short-term infliximab therapy on autoantibodies in systemic lupus erythematosus
    • DOI 10.1002/art.22327
    • Aringer M, Steiner G, Graninger WB, Höfler E, Steiner CW, Smolen JS,. Effects of short-term infliximab therapy on autoantibodies in systemic lupus erythematosus. Arthritis Rheum 2007; 56: 274-279. (Pubitemid 46106201)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.1 , pp. 274-279
    • Aringer, M.1    Steiner, G.2    Graninger, W.B.3    Hofler, E.4    Steiner, C.W.5    Smolen, J.S.6
  • 56
    • 0035421308 scopus 로고    scopus 로고
    • Activation of natural interferon-α producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines
    • DOI 10.1006/jaut.2001.0519
    • BÃ¥ve U, Vallin H, Alm GV, Rönnblom L,. Activation of natural interferon-alpha producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines. J Autoimmun 2001; 17: 71-80. (Pubitemid 32751883)
    • (2001) Journal of Autoimmunity , vol.17 , Issue.1 , pp. 71-80
    • Bave, U.1    Vallin, H.2    Alm, G.V.3    Ronnblom, L.4
  • 57
    • 0035892750 scopus 로고    scopus 로고
    • In vivo neutralization of TNF-α promotes humoral autoimmunity by preventing the induction of CTL
    • Via CS, Shustov A, Rus V, Lang T, Nguyen P, Finkelman FD,. In vivo neutralization of TNF-alpha promotes humoral autoimmunity by preventing the induction of CTL. J Immunol 2001; 167: 6821-6826. (Pubitemid 33144173)
    • (2001) Journal of Immunology , vol.167 , Issue.12 , pp. 6821-6826
    • Via, C.S.1    Shustov, A.2    Rus, V.3    Lang, T.4    Nguyen, P.5    Finkelman, F.D.6
  • 58
    • 0031048768 scopus 로고    scopus 로고
    • Circulating levels of tumor necrosis factor soluble receptors in systemic lupus erythematosus are significantly higher than in other rheumatic diseases and correlate with disease activity
    • Gabay C, Cakir N, Moral F, et al. Circulating levels of tumor necrosis factor soluble receptors in systemic lupus erythematosus are significantly higher than in other rheumatic diseases and correlate with disease activity. J Rheumatol 1997; 24: 303-308. (Pubitemid 27104093)
    • (1997) Journal of Rheumatology , vol.24 , Issue.2 , pp. 303-308
    • Gabay, C.1    Cakir, N.2    Moral, F.3    Roux-Lombard, P.4    Meyer, O.5    Dayer, J.-M.6    Vischer, T.7    Yazici, H.8    Guerne, P.-A.9
  • 59
    • 48749118802 scopus 로고    scopus 로고
    • Efficacy and safety of TNF-blocker therapy in systemic lupus erythematosus
    • Aringer M, Smolen JS,. Efficacy and safety of TNF-blocker therapy in systemic lupus erythematosus. Expert Opin Drug Saf 2008; 7: 411-419.
    • (2008) Expert Opin Drug Saf , vol.7 , pp. 411-419
    • Aringer, M.1    Smolen, J.S.2
  • 60
    • 0033774517 scopus 로고    scopus 로고
    • Association of a promoter polymorphism of tumor necrosis factor-alpha with subacute cutaneous lupus erythematosus and distinct photoregulation of transcription
    • Werth VP, Zhang W, Dortzbach K, Sullivan K,. Association of a promoter polymorphism of tumor necrosis factor-alpha with subacute cutaneous lupus erythematosus and distinct photoregulation of transcription. J Invest Dermatol 2000; 115: 726-730.
    • (2000) J Invest Dermatol , vol.115 , pp. 726-730
    • Werth, V.P.1    Zhang, W.2    Dortzbach, K.3    Sullivan, K.4
  • 61
    • 27744533607 scopus 로고    scopus 로고
    • Proinflammatory cytokine (IL-1β, IL-6, IL-12, IL-18 and TNF-α) levels in sera of patients with subacute cutaneous lupus erythematosus (SCLE)
    • DOI 10.1016/j.imlet.2005.08.001, PII S0165247805001860
    • Maczynska I, Millo B, Ratajczak-Stefańska V, et al. Proinflammatory cytokine (IL-1beta, IL-6, IL-12, IL-18 and TNF-alpha) levels in sera of patients with subacute cutaneous lupus erythematosus (SCLE). Immunol Lett 2006; 102: 79-82. (Pubitemid 41606043)
    • (2006) Immunology Letters , vol.102 , Issue.1 , pp. 79-82
    • Maczynska, I.1    Millo, B.2    Ratajczak-Stefanska, V.3    Maleszka, R.4    Szych, Z.5    Kurpisz, M.6    Giedrys-Kalemba, S.7
  • 62
    • 33645115417 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha is expressed in refractory skin lesions from patients with subacute cutaneous lupus erythematosus
    • Zampieri S, Alaibac M, Iaccarino L, et al. Tumour necrosis factor alpha is expressed in refractory skin lesions from patients with subacute cutaneous lupus erythematosus. Ann Rheum Dis 2006; 65: 545-548.
    • (2006) Ann Rheum Dis , vol.65 , pp. 545-548
    • Zampieri, S.1    Alaibac, M.2    Iaccarino, L.3
  • 65
    • 80052077348 scopus 로고    scopus 로고
    • Cutaneous lupus erythematosus induced by etanercept
    • (in Japanese).
    • Hattori M, Nishide T, Yamanouchi K,. Cutaneous lupus erythematosus induced by etanercept. J Visual Dermatol 2010; 9: 840-841 (in Japanese).
    • (2010) J Visual Dermatol , vol.9 , pp. 840-841
    • Hattori, M.1    Nishide, T.2    Yamanouchi, K.3
  • 66
    • 77953980528 scopus 로고    scopus 로고
    • IL-6: From its discovery to clinical applications
    • Kishimoto T,. IL-6: from its discovery to clinical applications. Int Immunol 2010; 22: 347-352.
    • (2010) Int Immunol , vol.22 , pp. 347-352
    • Kishimoto, T.1
  • 67
    • 2942752122 scopus 로고    scopus 로고
    • Rationale for interleukin-6 blockade in systemic lupus erythematosus
    • DOI 10.1191/0961203304lu1023oa
    • Tackey E, Lipsky PE, Illei GG,. Rationale for interleukin-6 blockade in systemic lupus erythematosus. Lupus 2004; 13: 339-343. (Pubitemid 38788493)
    • (2004) Lupus , vol.13 , Issue.5 , pp. 339-343
    • Tackey, E.1    Lipsky, P.E.2    Illei, G.G.3
  • 68
    • 0025854604 scopus 로고
    • Age-associated increase in interleukin 6 in MRL/lpr mice
    • Tang B, Matsuda T, Akira S, et al. Age-associated increase in interleukin 6 in MRL/lpr mice. Int Immunol 1991; 3: 273-278.
    • (1991) Int Immunol , vol.3 , pp. 273-278
    • Tang, B.1    Matsuda, T.2    Akira, S.3
  • 75
    • 69149106547 scopus 로고    scopus 로고
    • Monocytes and T lymphocytes contribute to a predominance of interleukin 6 and interleukin 10 in systemic lupus erythematosus
    • Mellor-Pita S, Citores MJ, Castejon R, et al. Monocytes and T lymphocytes contribute to a predominance of interleukin 6 and interleukin 10 in systemic lupus erythematosus. Cytometry B Clin Cytom 2009; 76B: 261-270.
    • (2009) Cytometry B Clin Cytom , vol.76 B , pp. 261-270
    • Mellor-Pita, S.1    Citores, M.J.2    Castejon, R.3
  • 76
    • 34548223736 scopus 로고    scopus 로고
    • Cytokine IL-6 and IL-10 as biomarkers in systemic lupus erythematosus
    • Chun HY, Chung JW, Kim HA, et al. Cytokine IL-6 and IL-10 as biomarkers in systemic lupus erythematosus. J Clin Immunol 2007; 27: 461-466.
    • (2007) J Clin Immunol , vol.27 , pp. 461-466
    • Chun, H.Y.1    Chung, J.W.2    Kim, H.A.3
  • 77
    • 75749113331 scopus 로고    scopus 로고
    • Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase i dosage-escalation study
    • Illei GG, Shirota Y, Yarboro CH, et al. Tocilizumab in systemic lupus erythematosus: data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study. Arthritis Rheum 2010; 62: 542-552.
    • (2010) Arthritis Rheum , vol.62 , pp. 542-552
    • Illei, G.G.1    Shirota, Y.2    Yarboro, C.H.3
  • 78
    • 54249137345 scopus 로고    scopus 로고
    • The influence of antimalarial treatment on IL-1beta, IL-6 and TNF-alpha mRNA expression on UVB-irradiated skin in systemic lupus erythematosus
    • Wozniacka A, Lesiak A, Boncela J, Smolarczyk K, McCauliffe DP, Sysa-Jedrzejowska A,. The influence of antimalarial treatment on IL-1beta, IL-6 and TNF-alpha mRNA expression on UVB-irradiated skin in systemic lupus erythematosus. Br J Dermatol 2008; 159: 1124-1130.
    • (2008) Br J Dermatol , vol.159 , pp. 1124-1130
    • Wozniacka, A.1    Lesiak, A.2    Boncela, J.3    Smolarczyk, K.4    McCauliffe, D.P.5    Sysa-Jedrzejowska, A.6
  • 84
    • 0033883903 scopus 로고    scopus 로고
    • Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus
    • Llorente L, Richaud-Patin Y, García-Padilla C, et al. Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus. Arthritis Rheum 2000; 43: 1790-1800.
    • (2000) Arthritis Rheum , vol.43 , pp. 1790-1800
    • Llorente, L.1    Richaud-Patin, Y.2    García-Padilla, C.3
  • 85
    • 59549083038 scopus 로고    scopus 로고
    • Interleukin-17 as a drug target in human disease
    • Ivanov S, Lindén A,. Interleukin-17 as a drug target in human disease. Trends Pharmacol Sci 2009; 30: 95-103.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 95-103
    • Ivanov, S.1    Lindén, A.2
  • 86
    • 67650657499 scopus 로고    scopus 로고
    • Interleukin-17 and systemic lupus erythematosus: Current concepts
    • Nalbandian A, Crispín JC, Tsokos GC,. Interleukin-17 and systemic lupus erythematosus: current concepts. Clin Exp Immunol 2009; 157: 209-215.
    • (2009) Clin Exp Immunol , vol.157 , pp. 209-215
    • Nalbandian, A.1    Crispín, J.C.2    Tsokos, G.C.3
  • 87
    • 70349238893 scopus 로고    scopus 로고
    • The role of IL-23/IL-17 axis in lupus nephritis
    • Zhang Z, Kyttaris VC, Tsokos GC,. The role of IL-23/IL-17 axis in lupus nephritis. J Immunol 2009; 183: 3160-3169.
    • (2009) J Immunol , vol.183 , pp. 3160-3169
    • Zhang, Z.1    Kyttaris, V.C.2    Tsokos, G.C.3
  • 88
    • 80052065948 scopus 로고    scopus 로고
    • Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: Implications for Th17-mediated inflammation in auto-immunity
    • Wong CK, Lit LC, Tam LS, Li EK, Wong PT, Lam CW,. Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity. J Autoimmun 2008; 31: 79-89.
    • (2008) J Autoimmun , vol.31 , pp. 79-89
    • Wong, C.K.1    Lit, L.C.2    Tam, L.S.3    Li, E.K.4    Wong, P.T.5    Lam, C.W.6
  • 89
    • 66049151440 scopus 로고    scopus 로고
    • Th17 and natural Treg cell population dynamics in systemic lupus erythematosus
    • Yang J, Chu Y, Yang X, et al. Th17 and natural Treg cell population dynamics in systemic lupus erythematosus. Arthritis Rheum 2009; 60: 1472-1483.
    • (2009) Arthritis Rheum , vol.60 , pp. 1472-1483
    • Yang, J.1    Chu, Y.2    Yang, X.3
  • 90
    • 58849162766 scopus 로고    scopus 로고
    • Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys
    • Crispín JC, Oukka M, Bayliss G, et al. Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys. J Immunol 2008; 181: 8761-8766.
    • (2008) J Immunol , vol.181 , pp. 8761-8766
    • Crispín, J.C.1    Oukka, M.2    Bayliss, G.3
  • 91
    • 0038281377 scopus 로고    scopus 로고
    • IL-17 induces autoantibody overproduction and peripheral blood mononuclear cell overexpression of IL-6 in lupus nephritis patients
    • Dong G, Ye R, Shi W, et al. IL-17 induces autoantibody overproduction and peripheral blood mononuclear cell overexpression of IL-6 in lupus nephritis patients. Chin Med J (Engl) 2003; 116: 543-548. (Pubitemid 36675854)
    • (2003) Chinese Medical Journal , vol.116 , Issue.4 , pp. 543-548
    • Dong, G.1    Ye, R.2    Shi, W.3    Liu, S.4    Wang, T.5    Yang, X.6    Yang, N.7    Yu, X.8
  • 95
    • 69949149477 scopus 로고    scopus 로고
    • IL-18 activity in systemic lupus erythematosus
    • Favilli F, Anzilotti C, Martinelli L, et al. IL-18 activity in systemic lupus erythematosus. Ann NY Acad Sci 2009; 1173: 301-309.
    • (2009) Ann NY Acad Sci , vol.1173 , pp. 301-309
    • Favilli, F.1    Anzilotti, C.2    Martinelli, L.3
  • 97
    • 0033786599 scopus 로고    scopus 로고
    • Elevation of plasma interleukin-18 concentration is correlated with disease activity in systemic lupus erythematosus
    • Wong CK, Li EK, Ho CY, Lam CW,. Elevation of plasma interleukin-18 concentration is correlated with disease activity in systemic lupus erythematosus. Rheumatology (Oxford) 2000; 39: 1078-1081.
    • (2000) Rheumatology (Oxford) , vol.39 , pp. 1078-1081
    • Wong, C.K.1    Li, E.K.2    Ho, C.Y.3    Lam, C.W.4
  • 98
    • 4644286915 scopus 로고    scopus 로고
    • Up-regulation of IL-18 and predominance of a Th1 immune response is a hallmark of lupus nephritis
    • DOI 10.1111/j.1365-2249.2004.02588.x
    • Calvani N, Richards HB, Tucci M, Pannarale G, Silvestris F,. Up-regulation of IL-18 and predominance of a Th1 immune response is a hallmark of lupus nephritis. Clin Exp Immunol 2004; 138: 171-178. (Pubitemid 39279981)
    • (2004) Clinical and Experimental Immunology , vol.138 , Issue.1 , pp. 171-178
    • Calvani, N.1    Richards, H.B.2    Tucci, M.3    Pannarale, G.4    Silvestris, F.5
  • 99
    • 0035988654 scopus 로고    scopus 로고
    • Increased IL-18 in patients with systemic lupus erythematosus: Relations with Th-1, Th-2, pro-inflammatory cytokines and disease activity. IL-18 is a marker of disease activity but does not correlate with pro-inflammatory cytokines
    • Amerio P, Frezzolini A, Abeni D, et al. Increased IL-18 in patients with systemic lupus erythematosus: relations with Th-1, Th-2, pro-inflammatory cytokines and disease activity. IL-18 is a marker of disease activity but does not correlate with pro-inflammatory cytokines. Clin Exp Rheumatol 2002; 20: 535-538. (Pubitemid 34846629)
    • (2002) Clinical and Experimental Rheumatology , vol.20 , Issue.4 , pp. 535-538
    • Amerio, P.1    Frezzolini, A.2    Abeni, D.3    Teofoli, P.4    Girardelli, C.R.5    De Pita, O.6    Puddu, P.7
  • 100
    • 38149007115 scopus 로고    scopus 로고
    • Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: Role of interleukin-18
    • Tucci M, Quatraro C, Lombardi L, Pellegrino C, Dammacco F, Silvestris F,. Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: role of interleukin-18. Arthritis Rheum 2008; 58: 251-262.
    • (2008) Arthritis Rheum , vol.58 , pp. 251-262
    • Tucci, M.1    Quatraro, C.2    Lombardi, L.3    Pellegrino, C.4    Dammacco, F.5    Silvestris, F.6
  • 101
    • 75349084506 scopus 로고    scopus 로고
    • High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein
    • Novick D, Elbirt D, Miller G, Dinarello CA, Rubinstein M, Sthoeger ZM,. High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein. J Autoimmun 2010; 34: 121-126.
    • (2010) J Autoimmun , vol.34 , pp. 121-126
    • Novick, D.1    Elbirt, D.2    Miller, G.3    Dinarello, C.A.4    Rubinstein, M.5    Sthoeger, Z.M.6
  • 102
    • 54949137275 scopus 로고    scopus 로고
    • Evidence for a pathogenetic role of interleukin-18 in cutaneous lupus erythematosus
    • Wang D, Drenker M, Eiz-Vesper B, Werfel T, Wittmann M,. Evidence for a pathogenetic role of interleukin-18 in cutaneous lupus erythematosus. Arthritis Rheum 2008; 58: 3205-3215.
    • (2008) Arthritis Rheum , vol.58 , pp. 3205-3215
    • Wang, D.1    Drenker, M.2    Eiz-Vesper, B.3    Werfel, T.4    Wittmann, M.5
  • 103
    • 0037238548 scopus 로고    scopus 로고
    • IL-12 completely blocks ultraviolet-induced secretion of tumor necrosis factor α from cultured skin fibroblasts and keratinocytes
    • DOI 10.1046/j.1523-1747.2003.12012.x
    • Werth VP, Bashir MM, Zhang W,. IL-12 completely blocks ultraviolet-induced secretion of tumor necrosis factor alpha from cultured skin fibroblasts and keratinocytes. J Invest Dermatol 2003; 120: 116-122. (Pubitemid 36120980)
    • (2003) Journal of Investigative Dermatology , vol.120 , Issue.1 , pp. 116-122
    • Werth, V.P.1    Bashir, M.M.2    Zhang, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.