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Volumn 19, Issue 2, 2010, Pages 123-131

Tyrosine kinase 2 and interferon regulatory factor 5 polymorphisms are associated with discoid and subacute cutaneous lupus erythematosus

Author keywords

CTLA4; Interferon pathway; IRF5; TYK2

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERFERON REGULATORY FACTOR 5; PROTEIN TYROSINE KINASE;

EID: 75149174779     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2009.00982.x     Document Type: Article
Times cited : (75)

References (52)
  • 1
    • 12344269042 scopus 로고    scopus 로고
    • 1st International Conference on Cutaneous Lupus Erythematosus Dusseldorf, Germany, September 1-5, 2004
    • Kuhn A, Rondinone R, Doria A, Shoenfeld Y. 1st International Conference on Cutaneous Lupus Erythematosus Dusseldorf, Germany, September 1-5, 2004. Autoimmun Rev 2005, 4:66-78.
    • (2005) Autoimmun Rev , vol.4 , pp. 66-78
    • Kuhn, A.1    Rondinone, R.2    Doria, A.3    Shoenfeld, Y.4
  • 2
    • 33750067967 scopus 로고    scopus 로고
    • Cutaneous lupus erythematosus: understanding of clinical features, genetic basis, and pathobiology of disease guides therapeutic strategies
    • Lee H J, Sinha A A. Cutaneous lupus erythematosus: understanding of clinical features, genetic basis, and pathobiology of disease guides therapeutic strategies. Autoimmunity 2006, 39:433-444.
    • (2006) Autoimmunity , vol.39 , pp. 433-444
    • Lee, H.J.1    Sinha, A.A.2
  • 3
    • 21244489263 scopus 로고    scopus 로고
    • Subacute cutaneous lupus erythematosus: 25-year evolution of a prototypic subset (subphenotype) of lupus erythematosus defined by characteristic cutaneous, pathological, immunological, and genetic findings
    • Sontheimer R D. Subacute cutaneous lupus erythematosus: 25-year evolution of a prototypic subset (subphenotype) of lupus erythematosus defined by characteristic cutaneous, pathological, immunological, and genetic findings. Autoimmun Rev 2005, 4:253-263.
    • (2005) Autoimmun Rev , vol.4 , pp. 253-263
    • Sontheimer, R.D.1
  • 4
    • 0031040680 scopus 로고    scopus 로고
    • Epidemiology and socioeconomic impact of skin disease in lupus erythematosus
    • Tebbe B, Orfanos C E. Epidemiology and socioeconomic impact of skin disease in lupus erythematosus. Lupus 1997, 6:96-104.
    • (1997) Lupus , vol.6 , pp. 96-104
    • Tebbe, B.1    Orfanos, C.E.2
  • 6
    • 3042652951 scopus 로고    scopus 로고
    • Immunology of cutaneous lupus erythematosus
    • Angotti C. Immunology of cutaneous lupus erythematosus. Clin Dermatol 2004, 22:105-112.
    • (2004) Clin Dermatol , vol.22 , pp. 105-112
    • Angotti, C.1
  • 7
    • 0023430013 scopus 로고
    • The application of genetic epidemiology to systemic lupus erythematosus
    • Hochberg M C. The application of genetic epidemiology to systemic lupus erythematosus. J Rheumatol 1987, 14:867-869.
    • (1987) J Rheumatol , vol.14 , pp. 867-869
    • Hochberg, M.C.1
  • 8
    • 0026537198 scopus 로고
    • A revised estimate of twin concordance in systemic lupus erythematosus
    • Deapen D, Escalante A, Weinrib L. A revised estimate of twin concordance in systemic lupus erythematosus. Arthritis Rheum 1992, 35:311-318.
    • (1992) Arthritis Rheum , vol.35 , pp. 311-318
    • Deapen, D.1    Escalante, A.2    Weinrib, L.3
  • 9
    • 21844432906 scopus 로고    scopus 로고
    • Infection, vaccines and other environmental triggers of autoimmunity
    • Molina V, Shoenfeld Y. Infection, vaccines and other environmental triggers of autoimmunity. Autoimmunity 2005, 38:235-245.
    • (2005) Autoimmunity , vol.38 , pp. 235-245
    • Molina, V.1    Shoenfeld, Y.2
  • 10
    • 13844292408 scopus 로고    scopus 로고
    • Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
    • Sigurdsson S, Nordmark G, Goring H H. Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet 2005, 76:528-537.
    • (2005) Am J Hum Genet , vol.76 , pp. 528-537
    • Sigurdsson, S.1    Nordmark, G.2    Goring, H.H.3
  • 11
    • 38649125210 scopus 로고    scopus 로고
    • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
    • Harley J B, Alarcon-Riquelme M E, Criswell L A. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 2008, 40:204-210.
    • (2008) Nat Genet , vol.40 , pp. 204-210
    • Harley, J.B.1    Alarcon-Riquelme, M.E.2    Criswell, L.A.3
  • 12
    • 40049108936 scopus 로고    scopus 로고
    • Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX
    • Hom G, Graham R R, Modrek B. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med 2008, 358:956-961.
    • (2008) N Engl J Med , vol.358 , pp. 956-961
    • Hom, G.1    Graham, R.R.2    Modrek, B.3
  • 13
    • 50849101942 scopus 로고    scopus 로고
    • A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5
    • Sigurdsson S, Nordmark G, Garnier S. A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5. Hum Mol Genet 2008, 17:2868-2876.
    • (2008) Hum Mol Genet , vol.17 , pp. 2868-2876
    • Sigurdsson, S.1    Nordmark, G.2    Garnier, S.3
  • 14
    • 34249860408 scopus 로고    scopus 로고
    • Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
    • Graham R R, Kyogoku C, Sigurdsson S. Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci U S A 2007, 104:6758-6763.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 6758-6763
    • Graham, R.R.1    Kyogoku, C.2    Sigurdsson, S.3
  • 15
    • 34548427925 scopus 로고    scopus 로고
    • STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus
    • Remmers E F, Plenge R M, Lee A T. STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N Engl J Med 2007, 357:977-986.
    • (2007) N Engl J Med , vol.357 , pp. 977-986
    • Remmers, E.F.1    Plenge, R.M.2    Lee, A.T.3
  • 16
    • 34247121966 scopus 로고    scopus 로고
    • Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches
    • Wenzel J, Tuting T. Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches. Exp Dermatol 2007, 16:454-463.
    • (2007) Exp Dermatol , vol.16 , pp. 454-463
    • Wenzel, J.1    Tuting, T.2
  • 17
    • 34447311899 scopus 로고    scopus 로고
    • Association of polymorphisms across the tyrosine kinase gene, TYK2 in UK SLE families
    • Graham D S, Akil M, Vyse T J. Association of polymorphisms across the tyrosine kinase gene, TYK2 in UK SLE families. Rheumatology (Oxford) 2007, 46:927-930.
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 927-930
    • Graham, D.S.1    Akil, M.2    Vyse, T.J.3
  • 18
    • 34248347860 scopus 로고    scopus 로고
    • The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus
    • Hellquist A, Zucchelli M, Kivinen K. The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus. J Med Genet 2007, 44:314-321.
    • (2007) J Med Genet , vol.44 , pp. 314-321
    • Hellquist, A.1    Zucchelli, M.2    Kivinen, K.3
  • 19
    • 54549093861 scopus 로고    scopus 로고
    • The genetics of SLE: an update in the light of genome-wide association studies
    • Rhodes B, Vyse T J. The genetics of SLE: an update in the light of genome-wide association studies. Rheumatology (Oxford) 2008, 47:1603-1611.
    • (2008) Rheumatology (Oxford) , vol.47 , pp. 1603-1611
    • Rhodes, B.1    Vyse, T.J.2
  • 20
    • 43249087817 scopus 로고    scopus 로고
    • Clinical and laboratory characteristics of Finnish lupus erythematosus patients with cutaneous manifestations
    • Koskenmies S, Järvinen T M, Onkamo P. Clinical and laboratory characteristics of Finnish lupus erythematosus patients with cutaneous manifestations. Lupus 2008, 17:337-347.
    • (2008) Lupus , vol.17 , pp. 337-347
    • Koskenmies, S.1    Järvinen, T.M.2    Onkamo, P.3
  • 21
    • 50449111452 scopus 로고    scopus 로고
    • Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
    • Graham R R, Cotsapas C, Davies L. Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet 2008, 40:1059-1061.
    • (2008) Nat Genet , vol.40 , pp. 1059-1061
    • Graham, R.R.1    Cotsapas, C.2    Davies, L.3
  • 22
    • 0035983749 scopus 로고    scopus 로고
    • Role of the Fcgamma receptor IIa polymorphism in susceptibility to systemic lupus erythematosus and lupus nephritis: a meta-analysis
    • Karassa F B, Trikalinos T A, Ioannidis J P. Role of the Fcgamma receptor IIa polymorphism in susceptibility to systemic lupus erythematosus and lupus nephritis: a meta-analysis. Arthritis Rheum 2002, 46:1563-1571.
    • (2002) Arthritis Rheum , vol.46 , pp. 1563-1571
    • Karassa, F.B.1    Trikalinos, T.A.2    Ioannidis, J.P.3
  • 23
    • 13244277850 scopus 로고    scopus 로고
    • A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
    • Prokunina L, Castillejo-Lopez C, Oberg F. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat Genet 2002, 32:666-669.
    • (2002) Nat Genet , vol.32 , pp. 666-669
    • Prokunina, L.1    Castillejo-Lopez, C.2    Oberg, F.3
  • 24
    • 18444395237 scopus 로고    scopus 로고
    • Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors
    • van Heel D A, Udalova I A, De Silva A P. Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. Hum Mol Genet 2002, 11:1281-1289.
    • (2002) Hum Mol Genet , vol.11 , pp. 1281-1289
    • van Heel, D.A.1    Udalova, I.A.2    De Silva, A.P.3
  • 25
    • 0347917232 scopus 로고    scopus 로고
    • Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus
    • Russell A I, Cunninghame Graham D S, Shepherd C. Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus. Hum Mol Genet 2004, 13:137-147.
    • (2004) Hum Mol Genet , vol.13 , pp. 137-147
    • Russell, A.I.1    Cunninghame Graham, D.S.2    Shepherd, C.3
  • 26
    • 27444447430 scopus 로고    scopus 로고
    • Differential effect of IL10 and TNF{alpha} genotypes on determining susceptibility to discoid and systemic lupus erythematosus
    • Suarez A, Lopez P, Mozo L, Gutierrez C. Differential effect of IL10 and TNF{alpha} genotypes on determining susceptibility to discoid and systemic lupus erythematosus. Ann Rheum Dis 2005, 64:1605-1610.
    • (2005) Ann Rheum Dis , vol.64 , pp. 1605-1610
    • Suarez, A.1    Lopez, P.2    Mozo, L.3    Gutierrez, C.4
  • 27
    • 33750207875 scopus 로고    scopus 로고
    • Evidence for unique association signals in SLE at the CD28-CTLA4-ICOS locus in a family-based study
    • Graham D S, Wong A K, McHugh N J, Whittaker J C, Vyse T J. Evidence for unique association signals in SLE at the CD28-CTLA4-ICOS locus in a family-based study. Hum Mol Genet 2006, 15:3195-3205.
    • (2006) Hum Mol Genet , vol.15 , pp. 3195-3205
    • Graham, D.S.1    Wong, A.K.2    McHugh, N.J.3    Whittaker, J.C.4    Vyse, T.J.5
  • 28
    • 33746957905 scopus 로고    scopus 로고
    • Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus
    • Kaufman K M, Kelly J A, Herring B J. Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus. Arthritis Rheum 2006, 54:2533-2540.
    • (2006) Arthritis Rheum , vol.54 , pp. 2533-2540
    • Kaufman, K.M.1    Kelly, J.A.2    Herring, B.J.3
  • 31
    • 0034986722 scopus 로고    scopus 로고
    • Immunolocalisation of the janus kinases (JAK) - signal transducers and activators of transcription (STAT) pathway in human epidermis
    • Nishio H, Matsui K, Tsuji H, Tamura A, Suzuki K. Immunolocalisation of the janus kinases (JAK) - signal transducers and activators of transcription (STAT) pathway in human epidermis. J Anat 2001, 198:581-589.
    • (2001) J Anat , vol.198 , pp. 581-589
    • Nishio, H.1    Matsui, K.2    Tsuji, H.3    Tamura, A.4    Suzuki, K.5
  • 32
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • Barrett J C, Fry B, Maller J, Daly M J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21:263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 33
    • 34547108380 scopus 로고    scopus 로고
    • JAK-STAT signaling: from interferons to cytokines
    • Schindler C, Levy D E, Decker T. JAK-STAT signaling: from interferons to cytokines. J Biol Chem 2007, 282:20059-20063.
    • (2007) J Biol Chem , vol.282 , pp. 20059-20063
    • Schindler, C.1    Levy, D.E.2    Decker, T.3
  • 34
    • 0034977353 scopus 로고    scopus 로고
    • Functional classification of interferon-stimulated genes identified using microarrays
    • De Veer M J, Holko M, Frevel M. Functional classification of interferon-stimulated genes identified using microarrays. J Leukoc Biol 2001, 69:912-920.
    • (2001) J Leukoc Biol , vol.69 , pp. 912-920
    • De Veer, M.J.1    Holko, M.2    Frevel, M.3
  • 35
    • 0034533825 scopus 로고    scopus 로고
    • Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies
    • Bengtsson A A, Sturfelt G, Truedsson L. Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies. Lupus 2000, 9:664-671.
    • (2000) Lupus , vol.9 , pp. 664-671
    • Bengtsson, A.A.1    Sturfelt, G.2    Truedsson, L.3
  • 36
    • 33845897463 scopus 로고    scopus 로고
    • Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity
    • Minegishi Y, Saito M, Morio T. Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity 2006, 25:745-755.
    • (2006) Immunity , vol.25 , pp. 745-755
    • Minegishi, Y.1    Saito, M.2    Morio, T.3
  • 37
    • 34247595806 scopus 로고    scopus 로고
    • Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus?
    • Reefman E, de Jong M C, Kuiper H. Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus? Arthritis Res Ther 2006, 8:R156.
    • (2006) Arthritis Res Ther , vol.8
    • Reefman, E.1    de Jong, M.C.2    Kuiper, H.3
  • 38
    • 49449104525 scopus 로고    scopus 로고
    • Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients
    • Niewold T B, Kelly J A, Flesch M H, Espinoza L R, Harley J B, Crow M K. Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients. Arthritis Rheum 2008, 58:2481-2487.
    • (2008) Arthritis Rheum , vol.58 , pp. 2481-2487
    • Niewold, T.B.1    Kelly, J.A.2    Flesch, M.H.3    Espinoza, L.R.4    Harley, J.B.5    Crow, M.K.6
  • 39
    • 0037171938 scopus 로고    scopus 로고
    • Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53
    • Mori T, Anazawa Y, Iiizumi M, Fukuda S, Nakamura Y, Arakawa H. Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53. Oncogene 2002, 21:2914-2918.
    • (2002) Oncogene , vol.21 , pp. 2914-2918
    • Mori, T.1    Anazawa, Y.2    Iiizumi, M.3    Fukuda, S.4    Nakamura, Y.5    Arakawa, H.6
  • 40
    • 0035724839 scopus 로고    scopus 로고
    • Apoptosis in different cutaneous manifestations of lupus erythematosus
    • Baima B, Sticherling M. Apoptosis in different cutaneous manifestations of lupus erythematosus. Br J Dermatol 2001, 144:958-966.
    • (2001) Br J Dermatol , vol.144 , pp. 958-966
    • Baima, B.1    Sticherling, M.2
  • 41
    • 33751393673 scopus 로고    scopus 로고
    • Interferon regulatory factor 5.2 acts as a transcription repressor of Epidermodysplasia verruciformis-associated human papillomaviruses
    • Akgul B, Curten M, Haigis H, Rogosz I, Pfister H. Interferon regulatory factor 5.2 acts as a transcription repressor of Epidermodysplasia verruciformis-associated human papillomaviruses. Arch Virol 2006, 151:2461-2473.
    • (2006) Arch Virol , vol.151 , pp. 2461-2473
    • Akgul, B.1    Curten, M.2    Haigis, H.3    Rogosz, I.4    Pfister, H.5
  • 42
    • 34548433979 scopus 로고    scopus 로고
    • A compass that points to lupus: genetic studies on type I interferon pathway
    • Kyogoku C, Tsuchiya N. A compass that points to lupus: genetic studies on type I interferon pathway. Genes Immun 2007, 8:445-455.
    • (2007) Genes Immun , vol.8 , pp. 445-455
    • Kyogoku, C.1    Tsuchiya, N.2
  • 43
    • 4444354041 scopus 로고    scopus 로고
    • Evidence for CTLA4 as a susceptibility gene for systemic lupus erythematosus
    • Barreto M, Santos E, Ferreira R. Evidence for CTLA4 as a susceptibility gene for systemic lupus erythematosus. Eur J Hum Genet 2004, 12:620-626.
    • (2004) Eur J Hum Genet , vol.12 , pp. 620-626
    • Barreto, M.1    Santos, E.2    Ferreira, R.3
  • 44
    • 17144378972 scopus 로고    scopus 로고
    • CTLA-4 polymorphisms and systemic lupus erythematosus (SLE): a meta-analysis
    • Lee Y H, Harley J B, Nath S K. CTLA-4 polymorphisms and systemic lupus erythematosus (SLE): a meta-analysis. Hum Genet 2005, 116:361-367.
    • (2005) Hum Genet , vol.116 , pp. 361-367
    • Lee, Y.H.1    Harley, J.B.2    Nath, S.K.3
  • 45
    • 23844433029 scopus 로고    scopus 로고
    • Association between discoid lupus erythematosus and cigarette smoking
    • Miot H A, Bartoli Miot L D, Haddad G R. Association between discoid lupus erythematosus and cigarette smoking. Dermatology 2005, 211:118-122.
    • (2005) Dermatology , vol.211 , pp. 118-122
    • Miot, H.A.1    Bartoli Miot, L.D.2    Haddad, G.R.3
  • 46
    • 0344492212 scopus 로고    scopus 로고
    • Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
    • Baechler E C, Batliwalla F M, Karypis G. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc Natl Acad Sci U S A 2003, 100:2610-2615.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2610-2615
    • Baechler, E.C.1    Batliwalla, F.M.2    Karypis, G.3
  • 47
    • 0034787636 scopus 로고    scopus 로고
    • A candidate gene analysis of three related photosensitivity disorders: cutaneous lupus erythematosus, polymorphic light eruption and actinic prurigo
    • Millard T P, Kondeatis E, Cox A. A candidate gene analysis of three related photosensitivity disorders: cutaneous lupus erythematosus, polymorphic light eruption and actinic prurigo. Br J Dermatol 2001, 145:229-236.
    • (2001) Br J Dermatol , vol.145 , pp. 229-236
    • Millard, T.P.1    Kondeatis, E.2    Cox, A.3
  • 48
    • 0033774517 scopus 로고    scopus 로고
    • Association of a promoter polymorphism of tumor necrosis factor-alpha with subacute cutaneous lupus erythematosus and distinct photoregulation of transcription
    • Werth V P, Zhang W, Dortzbach K, Sullivan K. Association of a promoter polymorphism of tumor necrosis factor-alpha with subacute cutaneous lupus erythematosus and distinct photoregulation of transcription. J Invest Dermatol 2000, 115:726-730.
    • (2000) J Invest Dermatol , vol.115 , pp. 726-730
    • Werth, V.P.1    Zhang, W.2    Dortzbach, K.3    Sullivan, K.4
  • 49
    • 37349032470 scopus 로고    scopus 로고
    • Identification of two independent risk factors for lupus within the MHC in United Kingdom families
    • Fernando M M, Stevens C R, Sabeti P C. Identification of two independent risk factors for lupus within the MHC in United Kingdom families. PLoS Genet 2007, 3:e192.
    • (2007) PLoS Genet , vol.3
    • Fernando, M.M.1    Stevens, C.R.2    Sabeti, P.C.3
  • 50
    • 0037281414 scopus 로고    scopus 로고
    • Homozygous single nucleotide polymorphism of the complement C1QA gene is associated with decreased levels of C1q in patients with subacute cutaneous lupus erythematosus
    • Racila D M, Sontheimer C J, Sheffield A, Wisnieski J J, Racila E, Sontheimer R D. Homozygous single nucleotide polymorphism of the complement C1QA gene is associated with decreased levels of C1q in patients with subacute cutaneous lupus erythematosus. Lupus 2003, 12:124-132.
    • (2003) Lupus , vol.12 , pp. 124-132
    • Racila, D.M.1    Sontheimer, C.J.2    Sheffield, A.3    Wisnieski, J.J.4    Racila, E.5    Sontheimer, R.D.6
  • 51
    • 34548327158 scopus 로고    scopus 로고
    • Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus
    • Lee-Kirsch M A, Gong M, Chowdhury D. Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus. Nat Genet 2007, 39:1065-1067.
    • (2007) Nat Genet , vol.39 , pp. 1065-1067
    • Lee-Kirsch, M.A.1    Gong, M.2    Chowdhury, D.3
  • 52
    • 30344437313 scopus 로고    scopus 로고
    • CTLA4 is differentially associated with autoimmune diseases in the Dutch population
    • Zhernakova A, Eerligh P, Barrera P. CTLA4 is differentially associated with autoimmune diseases in the Dutch population. Hum Genet 2005, 118:58-66.
    • (2005) Hum Genet , vol.118 , pp. 58-66
    • Zhernakova, A.1    Eerligh, P.2    Barrera, P.3


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