Synthesis and in vitro evaluation of methotrexate conjugated O,N-carboxymethyl chitosan via peptidyl spacers

Journal of Nanoparticle Research

Volumn 16, Issue 9, 2014, Pages

  Li, Dan ^a   Lu, Bo ^a   Zhang, Hong ^a   Huang, Zhijun ^a   Xu, Peihu ^a   Zheng, Hua ^a   Yin, Yihua ^a   Xu, Haixing ^a   Liu, Xia ^a   Lou, Yiceng ^a   Zhang, Xueqiong ^a   Xiong, Fuliang ^a  

^a WUHAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Carboxymethyl chitosan; Cathepsin X; Dipeptide spacer; Methotrexate; Prodrug

Indexed keywords

CARBOXYMETHYL CHITOSAN; CATHEPSIN X; DI-PEPTIDES; METHOTREXATE; PRODRUGS;

CHITOSAN; DIPEPTIDE; GLYCYLGLYCINE; GLYCYLPHENYLALANINE; METHOTREXATE; NANOPARTICLE; O, N CARBOXYMETHYL CHITOSAN; POLYMER; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; DRUG SYNTHESIS; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; FOURIER TRANSFORMATION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT;

EID: 84906041280     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-014-2609-6     Document Type: Article

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