Methotrexate-conjugated and hyperbranched polyglycerol-grafted Fe 3O4 magnetic nanoparticles for targeted anticancer effects

European Journal of Pharmaceutical Sciences

Volumn 48, Issue 1-2, 2013, Pages 111-120

  Li, Min ^a   Neoh, Koon Gee ^a   Wang, Rong ^a   Zong, Bao Yu ^b   Tan, Jia Yong ^c   Kang, En Tang ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b DATA STORAGE INSTITUTE   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Active targeting; Anticancer; Hyperbranched polyglycerol; Iron oxide nanoparticles; Methotrexate

Indexed keywords

GLYCEROL; HYPERBRANCHED POLYGLYCEROL; MAGNETITE NANOPARTICLE; METHOTREXATE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CANCER CELL CULTURE; CHEMICAL REACTION; CLICK CHEMISTRY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; ESTERIFICATION; FIBROBLAST; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; INCUBATION TIME; INFRARED SPECTROSCOPY; MACROPHAGE; PRIORITY JOURNAL; SOL GEL REACTION; ULTRAVIOLET SPECTROSCOPY; X RAY PHOTOELECTRON SPECTROSCOPY;

3T3 CELLS; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; ENDOCYTOSIS; GLYCEROL; HUMANS; MAGNETITE NANOPARTICLES; METHOTREXATE; MICE; NEOPLASMS; POLYMERS;

EID: 84872287124     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.10.008     Document Type: Article

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