Poly[N-(2-hydroxypropyl)methacrylamide] conjugates of methotrexate synthesis and in vitro drug release

Journal of Controlled Release

Volumn 49, Issue 2-3, 1997, Pages 123-132

  Subr V ^a   Strohalm, J ^a   Hirano, T ^b   Ito, Y ^b   Ulbrich, K ^a  

^a INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

^b NATL INST BIOSCI HUM TECHNOL   (Japan)

Author keywords

Cathepsin B; Controlled drug release; Drug conjugate; Methotrexate; N (2 hydroxypropyl)methacrylamide; Tritosomes

Indexed keywords

CATHEPSIN; DRUG CARRIER; METHOTREXATE; POLY[N (2 HYDROXYPROPYL)METHACRYLAMIDE];

AMINO ACID ANALYSIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHORIOCARCINOMA; DRUG CONJUGATION; DRUG RELEASE; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; POLYMERIZATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0041461021     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(97)00063-1     Document Type: Article

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