Modulation of platelet activation and thrombus formation using a pan-PI3K inhibitor S14161

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Yi, Wenxiu ^a   Li, Qiang ^a   Shen, Jian ^a   Ren, Lijie ^a   Liu, Xiaohui ^a   Wang, Qi ^a   He, Sudan ^a   Wu, Qingyu ^a   Hu, Hu ^b   Mao, Xinliang ^a   Zhu, Li ^a  

^a SOOCHOW UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

8-ETHOXY-2-(4-FLUOROPHENYL)-3-NITRO-2H-CHROMENE; BENZOPYRAN DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; INTEGRIN; PADGEM PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; HUMAN; MALE; METABOLISM; MOUSE; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOSIS;

ANIMALS; BENZOPYRANS; BLOOD PLATELETS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INTEGRINS; MALE; MICE; P-SELECTIN; PHOSPHATIDYLINOSITOL 3-KINASES; PLATELET ACTIVATION; PLATELET ADHESIVENESS; PLATELET AGGREGATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; THROMBOSIS;

EID: 84905921965     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102394     Document Type: Article

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