LGR5 regulates survival through mitochondria-mediated apoptosis and by targeting the Wnt/β-catenin signaling pathway in colorectal cancer cells

Cellular Signalling

Volumn 26, Issue 11, 2014, Pages 2333-2342

  Hsu, Hung Chih ^a,b   Liu, Yi Shiuan ^b   Tseng, Kai Chi ^b   Tan, Bertrand Chin Ming ^b,c   Chen, Shu Jen ^b,c   Chen, Hua Chien ^b,c  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Colorectal cancer; LGR5; Wnt catenin signaling

Indexed keywords

ALPHA TUBULIN; BETA CATENIN; CYTOCHROME C; G PROTEIN COUPLED RECEPTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; LEUCINE RICH G PROTEIN COUPLED RECEPTOR 5; MYC PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; UNCLASSIFIED DRUG; DNA; LGR5 PROTEIN, HUMAN; LIPOCORTIN 5; TUMOR MARKER; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CULTURE; CELL SURVIVAL; CENTRIFUGATION; COLORECTAL CANCER; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WNT SIGNALING PATHWAY; COLORECTAL NEOPLASMS; DNA FRAGMENTATION; GENETICS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANNEXIN A5; APOPTOSIS; BETA CATENIN; CELL LINE, TUMOR; CELL SURVIVAL; COLORECTAL NEOPLASMS; DNA FRAGMENTATION; DNA, NEOPLASM; HUMANS; NEOPLASM PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; TUMOR MARKERS, BIOLOGICAL; WNT SIGNALING PATHWAY;

EID: 84905868662     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.07.004     Document Type: Article

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