메뉴 건너뛰기




Volumn 31, Issue 1, 2014, Pages 5-16

β-Thalassemia intermedia: A bird'S-eye view;β-Talasemi i̇ntermedya: Kuşbaki{dotless}şi{dotless}

Author keywords

Ineffective erythropoiesis; Iron chelation; Iron overload; Thalassemia; Thalassemia intermedia

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; BISPHOSPHONIC ACID DERIVATIVE; BOSENTAN; CALCIUM; DEFERASIROX; DEFERIPRONE; HYDROXYUREA; LOW MOLECULAR WEIGHT HEPARIN; PENTOXIFYLLINE; SILDENAFIL; ZINC;

EID: 84905868087     PISSN: 13007777     EISSN: 13085263     Source Type: Journal    
DOI: 10.4274/Tjh.2014.0032     Document Type: Review
Times cited : (33)

References (110)
  • 1
    • 0000735363 scopus 로고
    • A series of cases of splenomegaly in children and peculiar changes in bones; report of cases
    • Cooley TB, Lee P. A series of cases of splenomegaly in children and peculiar changes in bones; report of cases. Am J Dis Child 1927;34:347-363.
    • (1927) Am J Dis Child , vol.34 , pp. 347-363
    • Cooley, T.B.1    Lee, P.2
  • 2
    • 0001167586 scopus 로고
    • Mediterranean disease-"thalassemia" (erythroblastic anemia of Cooley): Associated pigment abnormalities simulating hemochromatosis
    • Whipple GH, Bradford WL. Mediterranean disease-"thalassemia" (erythroblastic anemia of Cooley): associated pigment abnormalities simulating hemochromatosis. J Pediatr 1936;9:279-311.
    • (1936) J Pediatr , vol.9 , pp. 279-311
    • Whipple, G.H.1    Bradford, W.L.2
  • 3
    • 0042577857 scopus 로고
    • Genetic basis of the thalassaemia diseases
    • Ingram VM, Stretton AO. Genetic basis of the thalassaemia diseases. Nature 1959;184:1903-1909.
    • (1959) Nature , vol.184 , pp. 1903-1909
    • Ingram, V.M.1    Stretton, A.O.2
  • 4
    • 79960149454 scopus 로고    scopus 로고
    • Thalassemia: The long road from the bedside through the laboratory to the community
    • Weatherall DJ. Thalassemia: the long road from the bedside through the laboratory to the community. Transfus Med 2011;21:218-223.
    • (2011) Transfus Med , vol.21 , pp. 218-223
    • Weatherall, D.J.1
  • 5
    • 0013846440 scopus 로고
    • Globin synthesis in thalassaemia: An in vitro study
    • Weatherall DJ, Clegg JB, Naughton MA. Globin synthesis in thalassaemia: an in vitro study. Nature 1965;208:1061-1065.
    • (1965) Nature , vol.208 , pp. 1061-1065
    • Weatherall, D.J.1    Clegg, J.B.2    Naughton, M.A.3
  • 6
    • 0019231085 scopus 로고
    • The thalassemia syndromes
    • Weatherall DJ. The thalassemia syndromes. Tex Rep Biol Med 1980;40:323-333.
    • (1980) Tex Rep Biol Med , vol.40 , pp. 323-333
    • Weatherall, D.J.1
  • 8
    • 73949124572 scopus 로고
    • Genetic and biochemical studies of intermediate types of Cooley's anaemia
    • Sturgeon P, Itano HA, Bergren WR. Genetic and biochemical studies of intermediate types of Cooley's anaemia. Br J Haematol 1955;1:264-277.
    • (1955) Br J Haematol , vol.1 , pp. 264-277
    • Sturgeon, P.1    Itano, H.A.2    Bergren, W.R.3
  • 11
    • 0031872838 scopus 로고    scopus 로고
    • Relationship between genotype and phenotype. Thalassemia intermedia
    • Galanello R, Cao A. Relationship between genotype and phenotype. Thalassemia intermedia. Ann N Y Acad Sci 1998;850:325-333.
    • (1998) Ann N Y Acad Sci , vol.850 , pp. 325-333
    • Galanello, R.1    Cao, A.2
  • 12
    • 3442885741 scopus 로고    scopus 로고
    • Thalassaemia: The long road from bedside to genome
    • Weatherall DJ. Thalassaemia: the long road from bedside to genome. Nat Rev Genet 2004;5:625-631.
    • (2004) Nat Rev Genet , vol.5 , pp. 625-631
    • Weatherall, D.J.1
  • 13
    • 0028942051 scopus 로고
    • Genetic interactions in thalassemia intermedia: Analysis of β-mutations, alpha-genotype, gamma-promoters, and β-LCR hypersensitive sites 2 and 4 in Italian patients
    • Camaschella C, Mazza U, Roetto A, Gottardi E, Parziale A, Travi M, Fattore S, Bacchiega D, Fiorelli G, Cappellini MD. Genetic interactions in thalassemia intermedia: analysis of β-mutations, alpha-genotype, gamma-promoters, and β-LCR hypersensitive sites 2 and 4 in Italian patients. Am J Hematol 1995;48:82-87.
    • (1995) Am J Hematol , vol.48 , pp. 82-87
    • Camaschella, C.1    Mazza, U.2    Roetto, A.3    Gottardi, E.4    Parziale, A.5    Travi, M.6    Fattore, S.7    Bacchiega, D.8    Fiorelli, G.9    Cappellini, M.D.10
  • 14
    • 0033536288 scopus 로고    scopus 로고
    • The β-thalassemias
    • Olivieri NF. The β-thalassemias. N Engl J Med 1999;341:99-109.
    • (1999) N Engl J Med , vol.341 , pp. 99-109
    • Olivieri, N.F.1
  • 18
    • 70449368579 scopus 로고    scopus 로고
    • Iron overload in thalassaemia intermedia: Reassessment of iron chelation strategies
    • Taher A, Hershko C, Cappellini MD. Iron overload in thalassaemia intermedia: reassessment of iron chelation strategies. Br J Haematol 2009;147:634-640.
    • (2009) Br J Haematol , vol.147 , pp. 634-640
    • Taher, A.1    Hershko, C.2    Cappellini, M.D.3
  • 20
    • 77955915545 scopus 로고    scopus 로고
    • Pathogenesis and management of iron toxicity in thalassemia
    • Hershko C. Pathogenesis and management of iron toxicity in thalassemia. Ann N Y Acad Sci 2010;1202:1-9.
    • (2010) Ann N Y Acad Sci , vol.1202 , pp. 1-9
    • Hershko, C.1
  • 21
    • 80455143324 scopus 로고    scopus 로고
    • Elevated liver iron concentration is a marker of increased morbidity in patients with β thalassemia intermedia
    • Musallam KM, Cappellini MD, Wood JC, Motta I, Graziadei G, Tamim H, Taher AT. Elevated liver iron concentration is a marker of increased morbidity in patients with β thalassemia intermedia. Haematologica 2011;96:1605-1612.
    • (2011) Haematologica , vol.96 , pp. 1605-1612
    • Musallam, K.M.1    Cappellini, M.D.2    Wood, J.C.3    Motta, I.4    Graziadei, G.5    Tamim, H.6    Taher, A.T.7
  • 22
    • 84876282837 scopus 로고    scopus 로고
    • Serum ferritin levels and morbidity in beta thalassemia intermedia: A 10-year cohort study [abstract]
    • Musallam KM, Cappellini MD, Daar S, Karimi M, El-Beshlawy A, Taher AT. Serum ferritin levels and morbidity in beta thalassemia intermedia: a 10-year cohort study [abstract]. Blood 2012;120:1021.
    • (2012) Blood , vol.120 , pp. 1021
    • Musallam, K.M.1    Cappellini, M.D.2    Daar, S.3    Karimi, M.4    El-Beshlawy, A.5    Taher, A.T.6
  • 24
    • 84865977512 scopus 로고    scopus 로고
    • Longitudinal changes in serum ferritin levels correlate with measures of hepatic stiffness in transfusion-independent patients with β-thalassemia intermedia
    • Musallam KM, Motta I, Salvatori M, Fraquelli M, Marcon A, Taher AT, Cappellini MD. Longitudinal changes in serum ferritin levels correlate with measures of hepatic stiffness in transfusion-independent patients with β-thalassemia intermedia. Blood Cells Mol Dis 2012;49:136-139.
    • (2012) Blood Cells Mol Dis , vol.49 , pp. 136-139
    • Musallam, K.M.1    Motta, I.2    Salvatori, M.3    Fraquelli, M.4    Marcon, A.5    Taher, A.T.6    Cappellini, M.D.7
  • 25
    • 84876284207 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in hepatitis-negative patients with thalassemia intermedia: A closer look at the role of siderosis
    • Maakaron JE, Cappellini MD, Graziadei G, Ayache JB, Taher AT. Hepatocellular carcinoma in hepatitis-negative patients with thalassemia intermedia: a closer look at the role of siderosis. Ann Hepatol 2013;12:142-146.
    • (2013) Ann Hepatol , vol.12 , pp. 142-146
    • Maakaron, J.E.1    Cappellini, M.D.2    Graziadei, G.3    Ayache, J.B.4    Taher, A.T.5
  • 29
    • 0031848221 scopus 로고    scopus 로고
    • Adrenal extramedullary hematopoietic tumor in a patient with β-thalassemia
    • Chuang CK, Chu SH, Fang JT, Wu JH. Adrenal extramedullary hematopoietic tumor in a patient with β-thalassemia. J Formos Med Assoc 1998;97:431-433.
    • (1998) J Formos Med Assoc , vol.97 , pp. 431-433
    • Chuang, C.K.1    Chu, S.H.2    Fang, J.T.3    Wu, J.H.4
  • 30
    • 0029057360 scopus 로고
    • Case of the season. Thalassemia major with extramedullary hematopoiesis in the liver
    • Kumar A, Aggarwal S, de Tilly LN. Case of the season. Thalassemia major with extramedullary hematopoiesis in the liver. Semin Roentgenol 1995;30:99-101.
    • (1995) Semin Roentgenol , vol.30 , pp. 99-101
    • Kumar, A.1    Aggarwal, S.2    de Tilly, L.N.3
  • 31
    • 0005855010 scopus 로고
    • Extramedullary hematopoiesis in anemias
    • Brannan D. Extramedullary hematopoiesis in anemias. Bull Johns Hopkins Hosp 1927;41:104-135.
    • (1927) Bull Johns Hopkins Hosp , vol.41 , pp. 104-135
    • Brannan, D.1
  • 32
    • 0014540370 scopus 로고
    • Roentgen findings in extramedullary hematopoiesis
    • Ross P, Logan W. Roentgen findings in extramedullary hematopoiesis. AJR Am J Roentgenol 1969;106:604-613.
    • (1969) AJR Am J Roentgenol , vol.106 , pp. 604-613
    • Ross, P.1    Logan, W.2
  • 35
    • 0028102395 scopus 로고
    • Combined radiotherapeutic and surgical management of a spinal cord compression by extramedullary hematopoiesis in a patient with hemoglobin
    • Shin KH, Sharma S, Gregoritch SJ, Lifeso RM, Bettigole R, Yoon SS. Combined radiotherapeutic and surgical management of a spinal cord compression by extramedullary hematopoiesis in a patient with hemoglobin E β-thalassemia. Acta Haematol 1994;91:154-157.
    • (1994) E β-thalassemia. Acta Haematol , vol.91 , pp. 154-157
    • Shin, K.H.1    Sharma, S.2    Gregoritch, S.J.3    Lifeso, R.M.4    Bettigole, R.5    Yoon, S.S.6
  • 36
    • 0028908301 scopus 로고
    • Nonsurgical approach to paraparesis due to extramedullary hematopoiesis
    • Parsa K, Oreizy A. Nonsurgical approach to paraparesis due to extramedullary hematopoiesis. J Neurosurg 1995;82:657-660.
    • (1995) J Neurosurg , vol.82 , pp. 657-660
    • Parsa, K.1    Oreizy, A.2
  • 37
    • 0027664857 scopus 로고
    • Extramedullary hematopoiesis with intraspinal extension in thalassemia
    • Richter E. Extramedullary hematopoiesis with intraspinal extension in thalassemia. Aktuelle Radiol 1993;3:320-322.
    • (1993) Aktuelle Radiol , vol.3 , pp. 320-322
    • Richter, E.1
  • 38
    • 0027220613 scopus 로고
    • Recurrence of spinal cord compression from extramedullary hematopoiesis in thalassemia intermedia treated with low doses of radiotherapy
    • Dore F, Pardini S, Gaviano E, Longinotti M, Bonfigli S, Rovasio S, Tomiselli A, Cossu F. Recurrence of spinal cord compression from extramedullary hematopoiesis in thalassemia intermedia treated with low doses of radiotherapy. Am J Hematol 1993;44:148.
    • (1993) Am J Hematol , vol.44 , pp. 148
    • Dore, F.1    Pardini, S.2    Gaviano, E.3    Longinotti, M.4    Bonfigli, S.5    Rovasio, S.6    Tomiselli, A.7    Cossu, F.8
  • 39
    • 1342280392 scopus 로고    scopus 로고
    • Spinal cord compression in β-thalassemia: Case report and review of the literature
    • Salehi SA, Koski T, Ondra SL. Spinal cord compression in β-thalassemia: case report and review of the literature. Spinal Cord 2004;42:117-123.
    • (2004) Spinal Cord , vol.42 , pp. 117-123
    • Salehi, S.A.1    Koski, T.2    Ondra, S.L.3
  • 40
    • 77954533701 scopus 로고    scopus 로고
    • Paraspinal extramedullary hematopoiesis in patients with thalassemia intermedia
    • Haidar R, Mhaidli H, Taher AT. Paraspinal extramedullary hematopoiesis in patients with thalassemia intermedia. Eur Spine J 2010;19:871-878.
    • (2010) Eur Spine J , vol.19 , pp. 871-878
    • Haidar, R.1    Mhaidli, H.2    Taher, A.T.3
  • 41
    • 0020039135 scopus 로고
    • Juvenile leg ulceration in β-thalassemia major and intermedia
    • Gimmon Z, Wexler MR, Rachmilewitz EA. Juvenile leg ulceration in β-thalassemia major and intermedia. Plast Reconstr Surg 1982;69:320-325.
    • (1982) Plast Reconstr Surg , vol.69 , pp. 320-325
    • Gimmon, Z.1    Wexler, M.R.2    Rachmilewitz, E.A.3
  • 42
    • 79957652924 scopus 로고    scopus 로고
    • Healing of refractory leg ulcer in a patient with thalassemia intermedia and hypercoagulability after 14 years of unresponsive therapy
    • Levin C, Koren A. Healing of refractory leg ulcer in a patient with thalassemia intermedia and hypercoagulability after 14 years of unresponsive therapy. IMAJ 2011;13:316-318.
    • (2011) IMAJ , vol.13 , pp. 316-318
    • Levin, C.1    Koren, A.2
  • 45
    • 33749872392 scopus 로고    scopus 로고
    • Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran
    • Taher A, Isma'Eel H, Mehio G, Bignamini D, Kattamis A, Rachmilewitz EA, Cappellini MD. Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran. Thromb Haemost 2006;96:488-491.
    • (2006) Thromb Haemost , vol.96 , pp. 488-491
    • Taher, A.1    Isma'Eel, H.2    Mehio, G.3    Bignamini, D.4    Kattamis, A.5    Rachmilewitz, E.A.6    Cappellini, M.D.7
  • 48
    • 70449468812 scopus 로고    scopus 로고
    • Vascular complications after splenectomy for hematologic disorders
    • Crary SE, Buchanan GR. Vascular complications after splenectomy for hematologic disorders. Blood 2009;114:2861-2868.
    • (2009) Blood , vol.114 , pp. 2861-2868
    • Crary, S.E.1    Buchanan, G.R.2
  • 51
    • 0032697251 scopus 로고    scopus 로고
    • MR imaging of the brain: Findings in asymptomatic patients with thalassemia intermedia and sickle cell-thalassemia disease
    • Manfre L, Giarratano E, Maggio A, Banco A, Vaccaro G, Lagalla R. MR imaging of the brain: findings in asymptomatic patients with thalassemia intermedia and sickle cell-thalassemia disease. AJR Am J Roentgenol 1999;173:1477-1480.
    • (1999) AJR Am J Roentgenol , vol.173 , pp. 1477-1480
    • Manfre, L.1    Giarratano, E.2    Maggio, A.3    Banco, A.4    Vaccaro, G.5    Lagalla, R.6
  • 52
    • 73049084139 scopus 로고    scopus 로고
    • Asymptomatic brain magnetic resonance imaging abnormalities in splenectomized adults with thalassemia intermedia
    • Taher AT, Musallam KM, Nasreddine W, Hourani R, Inati A, Beydoun A. Asymptomatic brain magnetic resonance imaging abnormalities in splenectomized adults with thalassemia intermedia. J Thromb Haemost 2010;8:54-59.
    • (2010) J Thromb Haemost , vol.8 , pp. 54-59
    • Taher, A.T.1    Musallam, K.M.2    Nasreddine, W.3    Hourani, R.4    Inati, A.5    Beydoun, A.6
  • 53
    • 77950377763 scopus 로고    scopus 로고
    • Magnetic resonance evaluation of hepatic and myocardial iron deposition in transfusion-independent thalassemia intermedia compared to regularly transfused thalassemia major patients
    • Taher AT, Musallam KM, Wood JC, Cappellini MD. Magnetic resonance evaluation of hepatic and myocardial iron deposition in transfusion-independent thalassemia intermedia compared to regularly transfused thalassemia major patients. Am J Hematol 2010;85:288-290.
    • (2010) Am J Hematol , vol.85 , pp. 288-290
    • Taher, A.T.1    Musallam, K.M.2    Wood, J.C.3    Cappellini, M.D.4
  • 54
    • 46849112026 scopus 로고    scopus 로고
    • No evidence of cardiac iron in 20 never-or minimallytransfused patients with thalassemia intermedia
    • Origa R, Barella S, Argiolas GM, Bina P, Agus A, Galanello R. No evidence of cardiac iron in 20 never-or minimallytransfused patients with thalassemia intermedia. Haematologica 2008;93:1095-1096.
    • (2008) Haematologica , vol.93 , pp. 1095-1096
    • Origa, R.1    Barella, S.2    Argiolas, G.M.3    Bina, P.4    Agus, A.5    Galanello, R.6
  • 55
    • 80051660738 scopus 로고    scopus 로고
    • Iron chelation and neuroprotection in neurodegenerative diseases
    • Li X, Jankovic J, Le W. Iron chelation and neuroprotection in neurodegenerative diseases. J Neural Transm 2011;118:473-477.
    • (2011) J Neural Transm , vol.118 , pp. 473-477
    • Li, X.1    Jankovic, J.2    Le, W.3
  • 56
    • 56749163948 scopus 로고    scopus 로고
    • Pulmonary complications of sickle cell disease
    • Gladwin MT, Vichinsky E. Pulmonary complications of sickle cell disease. N Engl J Med 2008;359:2254-2265.
    • (2008) N Engl J Med , vol.359 , pp. 2254-2265
    • Gladwin, M.T.1    Vichinsky, E.2
  • 62
    • 33750089012 scopus 로고    scopus 로고
    • Splenectomy: A strong risk factor for pulmonary hypertension in patients with thalassaemia
    • Phrommintikul A, Sukonthasarn A, Kanjanavanit R, Nawarawong W. Splenectomy: a strong risk factor for pulmonary hypertension in patients with thalassaemia. Heart 2006;92:1467-1472.
    • (2006) Heart , vol.92 , pp. 1467-1472
    • Phrommintikul, A.1    Sukonthasarn, A.2    Kanjanavanit, R.3    Nawarawong, W.4
  • 63
    • 44949126303 scopus 로고    scopus 로고
    • Elevated levels of circulating procoagulant microparticles in patients with β-thalassemia intermedia
    • Habib A, Kunzelmann C, Shamseddeen W, Zobairi F, Freyssinet JM, Taher A. Elevated levels of circulating procoagulant microparticles in patients with β-thalassemia intermedia. Haematologica 2008;93:941-942.
    • (2008) Haematologica , vol.93 , pp. 941-942
    • Habib, A.1    Kunzelmann, C.2    Shamseddeen, W.3    Zobairi, F.4    Freyssinet, J.M.5    Taher, A.6
  • 64
    • 84893669300 scopus 로고    scopus 로고
    • Webthal Pulmonary Arterial Hypertension Group. Prevalence and risk factors for pulmonary arterial hypertension in a large group of β-thalassemia patients using right heart catheterization: A Webthal ® Study
    • Derchi G, Galanello R, Bina P, Cappellini MD, Piga A, Lai ME, Quarta A, Casu G, Perrotta S, Pinto V, Musallam KM, Forni GL; Webthal Pulmonary Arterial Hypertension Group. Prevalence and risk factors for pulmonary arterial hypertension in a large group of β-thalassemia patients using right heart catheterization: A Webthal ® Study. Circulation 2014;129:338-345.
    • (2014) Circulation , vol.129 , pp. 338-345
    • Derchi, G.1    Galanello, R.2    Bina, P.3    Cappellini, M.D.4    Piga, A.5    Lai, M.E.6    Quarta, A.7    Casu, G.8    Perrotta, S.9    Pinto, V.10    Musallam, K.M.11    Forni, G.L.12
  • 65
    • 0029640011 scopus 로고
    • Hypoxia of the renal medulla: Its implications for disease
    • Brezis M, Rosen S. Hypoxia of the renal medulla: its implications for disease. N Engl J Med 1995;332:647-655.
    • (1995) N Engl J Med , vol.332 , pp. 647-655
    • Brezis, M.1    Rosen, S.2
  • 66
    • 0344945513 scopus 로고    scopus 로고
    • Hypoxia-induced apoptosis in cultured glomerular endothelial cells: Involvement of mitochondrial pathways
    • Tanaka T, Miyata T, Inagi R, Kurokawa K, Adler S, Fujita T, Nangaku M. Hypoxia-induced apoptosis in cultured glomerular endothelial cells: involvement of mitochondrial pathways. Kidney Int 2003;64:2020-2032.
    • (2003) Kidney Int , vol.64 , pp. 2020-2032
    • Tanaka, T.1    Miyata, T.2    Inagi, R.3    Kurokawa, K.4    Adler, S.5    Fujita, T.6    Nangaku, M.7
  • 67
    • 0032830209 scopus 로고    scopus 로고
    • Hypoxia induces renal tubular epithelial cell apoptosis in chronic renal disease
    • Khan S, Cleveland RP, Koch CJ, Schelling JR. Hypoxia induces renal tubular epithelial cell apoptosis in chronic renal disease. Lab Invest 1999;79:1089-1099.
    • (1999) Lab Invest , vol.79 , pp. 1089-1099
    • Khan, S.1    Cleveland, R.P.2    Koch, C.J.3    Schelling, J.R.4
  • 68
    • 47149092668 scopus 로고    scopus 로고
    • Renal parenchymal hypoxia, hypoxia response and the progression of chronic kidney disease
    • Heyman SN, Khamaisi M, Rosen S, Rosenberger C. Renal parenchymal hypoxia, hypoxia response and the progression of chronic kidney disease. Am J Nephrol 2008;28:998-1006.
    • (2008) Am J Nephrol , vol.28 , pp. 998-1006
    • Heyman, S.N.1    Khamaisi, M.2    Rosen, S.3    Rosenberger, C.4
  • 69
    • 0032703190 scopus 로고    scopus 로고
    • Hypoxiainduced changes in extracellular matrix metabolism in renal cells
    • Norman JT, Orphanides C, Garcia P, Fine LG. Hypoxiainduced changes in extracellular matrix metabolism in renal cells. Exp Nephrol 1999;7:463-469.
    • (1999) Exp Nephrol , vol.7 , pp. 463-469
    • Norman, J.T.1    Orphanides, C.2    Garcia, P.3    Fine, L.G.4
  • 70
    • 0033662026 scopus 로고    scopus 로고
    • Hypoxia promotes fibrogenesis in human renal fibroblasts
    • Norman JT, Clark IM, Garcia PL. Hypoxia promotes fibrogenesis in human renal fibroblasts. Kidney Int 2000;58:2351-2366.
    • (2000) Kidney Int , vol.58 , pp. 2351-2366
    • Norman, J.T.1    Clark, I.M.2    Garcia, P.L.3
  • 71
    • 0034323610 scopus 로고    scopus 로고
    • Role of fibroblast activation in inducing interstitial fibrosis
    • Zeisberg M, Strutz F, Müller GA. Role of fibroblast activation in inducing interstitial fibrosis. J Nephrol 2000;13(Suppl 3):111-120.
    • (2000) J Nephrol , vol.13 , Issue.SUPPL. 3 , pp. 111-120
    • Zeisberg, M.1    Strutz, F.2    Müller, G.A.3
  • 72
    • 33645452371 scopus 로고    scopus 로고
    • Chronic hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure
    • Nangaku M. Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. J Am Soc Nephrol 2006;17:17-25.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 17-25
    • Nangaku, M.1
  • 75
    • 0016437234 scopus 로고
    • Function of the kidney in adult patients with Cooley's disease: A preliminary report
    • Mastrangelo F, Lopez T, Rizzelli S, Manisco G, Corlianò C, Alfonso L. Function of the kidney in adult patients with Cooley's disease: a preliminary report. Nephron 1975;14:229-236.
    • (1975) Nephron , vol.14 , pp. 229-236
    • Mastrangelo, F.1    Lopez, T.2    Rizzelli, S.3    Manisco, G.4    Corlianò, C.5    Alfonso, L.6
  • 76
    • 0026343053 scopus 로고
    • Hemodynamics and organ blood flow in fetal sheep subjected to chronic anemia
    • Davis LE, Hohimer AR. Hemodynamics and organ blood flow in fetal sheep subjected to chronic anemia. Am J Physiol 1991;261:R1542-R1548.
    • (1991) Am J Physiol , vol.261
    • Davis, L.E.1    Hohimer, A.R.2
  • 77
    • 0025897224 scopus 로고
    • Anemia: A potent modulator of renal hemodynamics in models of progressive renal disease
    • Lafferty HM, Anderson S, Brenner BM. Anemia: a potent modulator of renal hemodynamics in models of progressive renal disease. Am J Kidney Dis 1991;17(Suppl 1):2-7.
    • (1991) Am J Kidney Dis , vol.17 , Issue.SUPPL. 1 , pp. 2-7
    • Lafferty, H.M.1    Anderson, S.2    Brenner, B.M.3
  • 78
    • 0029902698 scopus 로고    scopus 로고
    • The hyperfiltration theory: A paradigm shift in nephrology
    • Brenner BM, Lawler EV, Mackenzie HS. The hyperfiltration theory: a paradigm shift in nephrology. Kidney Int 1996;49:1774-1777.
    • (1996) Kidney Int , vol.49 , pp. 1774-1777
    • Brenner, B.M.1    Lawler, E.V.2    Mackenzie, H.S.3
  • 81
    • 0025126555 scopus 로고
    • Role of free radicals and catalytic metal ions in human disease: An overview
    • Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol 1990;186:1-85.
    • (1990) Methods Enzymol , vol.186 , pp. 1-85
    • Halliwell, B.1    Gutteridge, J.M.2
  • 84
    • 79959520305 scopus 로고    scopus 로고
    • Health-related quality of life in adults with transfusion-independent thalassaemia intermedia compared to regularly transfused thalassaemia major: New insights
    • Musallam KM, Khoury B, Abi-Habib R, Bazzi L, Succar J, Halawi R, Hankir A, Koussa S, Taher AT. Health-related quality of life in adults with transfusion-independent thalassaemia intermedia compared to regularly transfused thalassaemia major: new insights. Eur J Haematol 2011;87:73-79.
    • (2011) Eur J Haematol , vol.87 , pp. 73-79
    • Musallam, K.M.1    Khoury, B.2    Abi-Habib, R.3    Bazzi, L.4    Succar, J.5    Halawi, R.6    Hankir, A.7    Koussa, S.8    Taher, A.T.9
  • 85
    • 82955187600 scopus 로고    scopus 로고
    • Levels of growth differentiation factor-15 are high and correlate with clinical severity in transfusionindependent patients with β thalassemia intermedia
    • Musallam KM, Taher AT, Duca L, Cesaretti C, Halawi R, Cappellini MD. Levels of growth differentiation factor-15 are high and correlate with clinical severity in transfusionindependent patients with β thalassemia intermedia. Blood Cells Mol Dis 2011;47:232-234.
    • (2011) Blood Cells Mol Dis , vol.47 , pp. 232-234
    • Musallam, K.M.1    Taher, A.T.2    Duca, L.3    Cesaretti, C.4    Halawi, R.5    Cappellini, M.D.6
  • 87
    • 34447135533 scopus 로고    scopus 로고
    • Modern treatment of thalassaemia intermedia
    • Borgna-Pignatti C. Modern treatment of thalassaemia intermedia. Br J Haematol 2007;138:291-304.
    • (2007) Br J Haematol , vol.138 , pp. 291-304
    • Borgna-Pignatti, C.1
  • 91
    • 0019944568 scopus 로고
    • Ferrioxamine excretion in iron-loaded man
    • Pippard MJ, Callender ST, Finch CA. Ferrioxamine excretion in iron-loaded man. Blood 1982;60:288-294.
    • (1982) Blood , vol.60 , pp. 288-294
    • Pippard, M.J.1    Callender, S.T.2    Finch, C.A.3
  • 92
    • 84905868680 scopus 로고    scopus 로고
    • Thalassemia International Federation, Cyprus, Thalassemia International Federation
    • Thalassemia International Federation. Guidelines for the Clinical Management of Thalassemia. Strovolos, Cyprus, Thalassemia International Federation, 2004.
    • (2004) Guidelines For the Clinical Management of Thalassemia. Strovolos
  • 93
    • 54349095611 scopus 로고    scopus 로고
    • Correlation of liver iron concentration determined by R2 magnetic resonance imaging with serum ferritin in patients with thalassemia intermedia
    • Taher A, El Rassi F, Isma'Eel H, Koussa S, Inati A, Cappellini MD. Correlation of liver iron concentration determined by R2 magnetic resonance imaging with serum ferritin in patients with thalassemia intermedia. Haematologica 2008;93:1584-1586.
    • (2008) Haematologica , vol.93 , pp. 1584-1586
    • Taher, A.1    El Rassi, F.2    Isma'Eel, H.3    Koussa, S.4    Inati, A.5    Cappellini, M.D.6
  • 94
    • 23744459788 scopus 로고    scopus 로고
    • MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusiondependent thalassemia and sickle cell disease patients
    • Wood JC, Enriquez C, Ghugre N, Tyzka JM, Carson S, Nelson MD, Coates TD. MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusiondependent thalassemia and sickle cell disease patients. Blood 2005;106:1460-1465.
    • (2005) Blood , vol.106 , pp. 1460-1465
    • Wood, J.C.1    Enriquez, C.2    Ghugre, N.3    Tyzka, J.M.4    Carson, S.5    Nelson, M.D.6    Coates, T.D.7
  • 96
    • 0035135479 scopus 로고    scopus 로고
    • Improving adherence with deferoxamine regimens for patients receiving chronic transfusion therapy
    • Treadwell MJ, Weissman L. Improving adherence with deferoxamine regimens for patients receiving chronic transfusion therapy. Semin Hematol 2001;38(Suppl 1): 77-84.
    • (2001) Semin Hematol , vol.38 , Issue.SUPPL. 1 , pp. 77-84
    • Treadwell, M.J.1    Weissman, L.2
  • 97
    • 15744381094 scopus 로고    scopus 로고
    • Overcoming the challenge of patient compliance with iron chelation therapy
    • Cappellini MD. Overcoming the challenge of patient compliance with iron chelation therapy. Semin Hematol 2005;42(Suppl 1):19-21.
    • (2005) Semin Hematol , vol.42 , Issue.SUPPL. 1 , pp. 19-21
    • Cappellini, M.D.1
  • 103
    • 23044442033 scopus 로고    scopus 로고
    • Hematologic and clinical responses of thalassemia intermedia patients to hydroxyurea during 6 years of therapy in Iran
    • Karimi M, Darzi H, Yavarian M. Hematologic and clinical responses of thalassemia intermedia patients to hydroxyurea during 6 years of therapy in Iran. J Pediatr Hematol Oncol 2005;27:380-385.
    • (2005) J Pediatr Hematol Oncol , vol.27 , pp. 380-385
    • Karimi, M.1    Darzi, H.2    Yavarian, M.3
  • 105
    • 0030039970 scopus 로고    scopus 로고
    • Reactivation of fetal hemoglobin in patients with β-thalassemia
    • Olivieri NF. Reactivation of fetal hemoglobin in patients with β-thalassemia. Semin Hematol 1996;33:24-42.
    • (1996) Semin Hematol , vol.33 , pp. 24-42
    • Olivieri, N.F.1
  • 110
    • 84867579481 scopus 로고    scopus 로고
    • Cerebral infarction in β-thalassemia intermedia: Breaking the silence
    • Musallam KM, Taher AT, Karimi M, Rachmilewitz EA. Cerebral infarction in β-thalassemia intermedia: breaking the silence. Thromb Res 2012;130:695-702.
    • (2012) Thromb Res , vol.130 , pp. 695-702
    • Musallam, K.M.1    Taher, A.T.2    Karimi, M.3    Rachmilewitz, E.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.