MR imaging of the brain: Findings in asymptomatic patients with thalassemia intermedia and sickle cell-thalassemia disease

American Journal of Roentgenology

Volumn 173, Issue 6, 1999, Pages 1477-1480

  Manfrè, Luigi ^a,d   Giarratano, Elio ^b   Maggio, Aurelio ^c   Banco, Aurelia ^a   Vaccaro, Giuseppe ^b   Lagalla, Roberto ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b S Elia Hospital   (Italy)

^c VILLA SOFIA CERVELLO HOSPITAL   (Italy)

^d NONE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BRAIN DISEASE; BRAIN ISCHEMIA; CHILD; CLINICAL ARTICLE; DIAGNOSTIC IMAGING; DISEASE SEVERITY; FEMALE; HEMATOLOGIC DISEASE; HUMAN; MALE; NEURORADIOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SICKLE CELL ANEMIA; THALASSEMIA;

EID: 0032697251     PISSN: 0361803X     EISSN: None     Source Type: Journal    
DOI: 10.2214/ajr.173.6.10584785     Document Type: Article

References (26)

1. Moser FG, Miller ST, Bello JA, et al. The spectrum of brain MR abnormalities in sickle-cell disease: a report from the cooperative study of sickle cell disease. AJNR 1996;17:965-972
2. Giambona A, Lo Gioco P, Marino M, et al. The great heterogeneity of thalassemia molecular defects in Sicily. Hum Genet 1995;95:526-530
3. Schiliro G, Spena M, Giambelluca E, Maggio A. Sickle hemoglobinopathies in Sicily. Am J Hematol 1990;33:81-85
4. Maggio A, Giambona A, Cai SP, Wall J, Kan YW, Chehab FF. Rapid and simultaneous typing of hemoglobin S, hemoglobin C and seven Mediterranean beta-thalassemia mutations by covalent reverse dot-blot analysis: application to prenatal diagnosis in Sicily. Blood 1993;81:239-242
5. Charache S, Terrin ML, Moore RD, et al. Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia: investigators of the multicenter study of hydroxyurea in sickle cell anemia. N Engl J Med 1995;332:1317-1322
6. Balkaran B, Char G, Morris JS, et al. Stroke in a cohort of patients with homozygous sickle cell disease. J Pediatr 1992;120:360-366
7. Zimmerman RA, Gill F, Goldberg HI, et al. MRI of sickle cell cerebral infarction. Neuroradiology 1987;29:232-237
8. Palvalakis SG, Bello J, Prohovnik I, et al. Brain infarction in sickle cell anemia: magnetic resonance imaging correlates. Ann Neurol 1988;23: 125-130
9. Brown RT, Buchannan I, Doepke K, et al. Cognitive and academic functioning in children with sickle cell disease. J Clin Child Psychol 1993;22: 207-218
10. Wasserman AL, Wilimas JA, Fairclough DL, et al. Subtle neuropsychological deficits in children with sickle cell disease. Am J Pediatr Hematol Oncol 1991;13:14-20
11. Mankad VN, Dyken PR. Neurological complication of sickle cell disease. In: Mankad VN, Moore RB, eds. Sickle cell disease: pathophysiology, diagnosis and management. Dayton, OH: Praeger, 1994:300-320
12. Kandeel AY, Zimmerman RA, Ohene-Frempong K. Comparison of magnetic resonance angiography and conventional angiography in sickle cell disease: clinical significance and reliability. Neuroradiology 1996;38:409-416
13. Golden GS. Stroke syndromes in childhood. Neurol Clin 1985;3:59-75
14. Merkel KH, Ginsberg PL, Parker JC Jr, Post MJ. Cerebrovascular disease in sickle cell anemia: a clinical, pathological and radiological correlation. Stroke 1978;9:45-52
15. Oppenheimer EH, Esterly JR. Pulmonary changes in sickle-cell disease. Am Rev Respir Dis 1971;103: 858-859
16. Francis RB. Large vessel occlusion in sickle cell disease: pathogenesis, clinical consequences, and therapeutic implications. Med Hypotheses 1991; 35:88-95
17. Livrea MA, Tesoriere L, Pintaudi AM, et al. Oxidative stress and antioxidant status in beta-thalassemia major: iron overload and depletion of lipid-soluble antioxidant. Blood 1996;88:3608-3614
18. Alliwel B, Gutteridge JMC. Role of the free radicals and catalytic metal ions in human disease: an overview. In: Packer L, Glazer AN, eds. Methods of enzymology, vol. 186. San Diego: Academic Press, 1990:1-11
19. Salonen O, Autti T, Raininko R, et al. MRI of the brain in neurologically healthy middle-aged and elderly individuals. Neuroradiology 1997;39: 537-545
20. Charache S. Fetal hemoglobin, sickling, and sickle cell disease. Adv Pediatr 1990;37:1-31
21. Michaeli J, Mittelman M, Grisaru D, Rachmilewitz E. Thromboembolic complications in beta thalassemia major. Acta Haematol 1992;87:71-74
22. Powars D, Wilson B, Imbus C, et al. The natural history of stroke in sickle cell disease. Am J Med 1978;65:461-471
23. Modell B, Berdoukas V. The clinical approach to thalassemia. New York: Grune and Stratton, 1984
24. Ogene-Frempong K. Stroke in sickle cell disease: demographic, clinical and therapeutic considerations. Semin Hematol 1991;28:213-219
25. Charache S, Terrin ML, Moore RD, et al. Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. N Engl J Med 1995;332: 1317-1322
26. Seeler RA, Royal JE, Powe L, Goldbarg HL. Moyamoya in children with sickle cell anemia and cerebrovascular occlusion. J Pediatr 1978;92: 808-810