Paraspinal extramedullary hematopoiesis in patients with thalassemia intermedia

European Spine Journal

Volumn 19, Issue 6, 2010, Pages 871-878

  Haidar, Rachid ^a   Mhaidli, Hani ^b   Taher, Ali T ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^b HOSPITAL UNIVERSITARIO DE CANARIAS   (Spain)

Author keywords

Extramedullary hematopoiesis; Review; Spine; Thalassemia intermedia

Indexed keywords

GADOLINIUM; HYDROXYUREA; STEROID;

BLOOD TRANSFUSION; CLINICAL FEATURE; DRUG MEGADOSE; EDEMA; EXTRAMEDULLARY HEMATOPOIESIS; HUMAN; LAMINECTOMY; MORBIDITY; MYELOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PARASPINAL EXTRAMEDULLARY HEMATOPOIESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RADIATION DOSE; REVIEW; SPINAL CORD DECOMPRESSION; SPINE DISEASE; SPINE RADIOGRAPHY; THALASSEMIA; THALASSEMIA INTERMEDIA; TREATMENT RESPONSE;

HEMATOLOGIC NEOPLASMS; HEMATOPOIESIS, EXTRAMEDULLARY; HUMANS; SPINAL NEOPLASMS; THALASSEMIA;

EID: 77954533701     PISSN: 09406719     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00586-010-1357-2     Document Type: Review

References (88)

1. Weatherall DJ, Clegg JB (2001) The thalassemia syndromes, 4th edn. Blackwell Scientific Publications, Oxford
2. A Taher H Ismaeel MD Cappellini 2006 Thalassaemia intermedia: revisited Blood Cells Mol Dis 37 12 20 10.1016/j.bcmd.2006.04.005 1:CAS:528: DC%2BD28XntFShurY%3D 16737833 (Pubitemid 44062361)
3. LD Cromwell C Kerber 1978 Spinal cord compression by extramedullary hematopoiesis in myeloid metaplasia Radiology 128 118 1:STN:280: DyaE1c3gtlSgsg%3D%3D 663196
4. SM Stahl G Ellinger JR Baringer 1979 Progressive myelopathy due to extramedullary hematopoiesis: case report and review of the literature Ann Neurol 5 485 489 10.1002/ana.410050515 1:STN:280:DyaE1M3jtVWktw%3D%3D 464550 (Pubitemid 9150144)
5. GP Rice LJ Assis RM Barr GC Ebers 1980 Extramedullary hematopoiesis and spinal cord compression complicating polycythemia rubra vera Ann Neurol 7 81 84 10.1002/ana.410070115 1:STN:280:DyaL3c7lt1SqsQ%3D%3D 7362209
6. G Cook RA Sharp 1994 Spinal cord compression due to extramedullary haemopoiesis in myelofibrosis J Clin Pathol 47 464 465 10.1136/jcp.47.5.464 1:STN:280:DyaK2c3pvFyqsQ%3D%3D 8027402
7. F Price H Bell 1985 Spinal cord compression due to extramedullary hematopoiesis. Successful treatment in a patient with longstanding myelofibrosis JAMA 253 2876 2877 10.1001/jama.253.19.2876 1:STN:280:DyaL2M7osFOqsw%3D%3D 3989965 (Pubitemid 15033090)
8. A Jackson IE Burton 1990 Retroperitoneal mass and spinal cord compression due to extramedullary haemopoiesis in polycythemia rubra vera Br J Radiol 42 91 92
9. AC McDonald G Cook RA Sharp D Bissett 1993 Spinal cord compression in myelofibrosis-a case report Acta Oncol 32 692 693 10.3109/02841869309092455 1:STN:280:DyaK2c%2FotlSmug%3D%3D 8260191
10. JC de Morais N Spector FP Lavrado LF Nobre JP de Mattos W Pulcheri M Nucci S Novis HP de Oliveira 1996 Spinal cord compression due to extramedullary hematopoiesis in the proliferative phase of polycythemia vera Acta Haematol 96 242 244 10.1159/000203792 8922492
11. M Haran S Ni 2001 Recurrent reversible paraplegia Lancet 357 1092 10.1016/S0140-6736(00)04262-8 1:STN:280:DC%2BD3M3jslyruw%3D%3D 11297961 (Pubitemid 32322541)
12. F Dore P Cianciulli S Rovasio L Oggiano S Bonfigli M Murineddu S Pardini G Simonetti G Gualdi G Papa, et al. 1992 Incidence and clinical study of ectopic erythropoiesis in adult patients with thalassemia intermedia Ann Ital Med Int 7 137 140 1:STN:280:DyaK3s%2FptVGntw%3D%3D 1457252
13. A Aessopos S Tassiopoulos D Farmakis I Moyssakis M Kati K Polonifi M Tsironi 2006 Extramedullary hematopoiesis-related pleural effusion: the case of beta-thalassemia Ann Thorac Surg 81 2037 2043 10.1016/j.athoracsur.2006.01.026 16731126 (Pubitemid 43775517)
14. CK Chuang SH Chu JT Fang JH Wu 1998 Adrenal extramedullary hematopoietic tumor in a patient with beta-thalassemia J Formos Med Assoc 97 431 433 1:STN:280:DyaK1czhsVWlsw%3D%3D 9650475
15. A Kumar S Aggarwal LN de Tilly 1995 Case of the season. Thalassemia major with extramedullary hematopoiesis in the liver Semin Roentgenol 30 99 101 10.1016/S0037-198X(05)80027-6 1:CAS:528:DyaK2MXltVKktbs%3D 7610407
16. D Brannan 1927 Extramedullary hematopoiesis in anemias Bull Johns Hopkins Hosp 41 104 135
17. P Ross W Logan 1969 Roentgen findings in extramedullary hematopoiesis AJR Am J Roentgenol 106 604 613 1:STN:280:DyaF1M3jsVCisQ%3D%3D
18. J Tsitouridis S Stamos E Hassapopoulou K Tsitouridis P Nikolopoulos 1999 Extramedullary paraspinal hematopoiesis in thalassemia: CT and MRI evaluation Eur J Radiol 30 33 38 10.1016/S0720-048X(98)00101-6 1:STN:280: DyaK1Mzhslansw%3D%3D 10389010 (Pubitemid 29281723)
19. L Pantongrag-Brown N Suwanwela 1992 Case report: chronic spinal cord compression from extramedullary haematopoiesis in thalassemia BMRI findings Clin Radiol 46 281 283 10.1016/S0009-9260(05)80172-2 1:STN:280: DyaK3s%2FkslKqsw%3D%3D 1424454
20. JL Da Costa YS Loh E Hanam 1974 Extramedullary hematopoiesis with multiple tumour-simulating mediastinal masses in hemoglobin E-thalassemia disease Chest 65 210 212 10.1378/chest.65.2.210 1:STN:280:DyaE2c%2FosV2msQ%3D%3D 4810684
21. A Lyall 1935 Massive extramedullary bone marrow formation in a case of pernicious anaemia J Pathol Bacteriol 41 469 472 10.1002/path.1700410310
22. SM Cone 1925 Bone marrow occurring in intercostal veins JAMA 84 1732 1733
23. E Cardia S Toscano G La Rosa C Zaccone D d'Avella F Tomasello 1994 Spinal cord compression in homozygous beta thalassemia intermedia Pediatr Neurosurg 20 186 189 10.1159/000120785 1:STN:280:DyaK2c3mtlyitQ%3D%3D 8204493
24. A Amirjamshidi K Abbassioun SE Ketabchi 1991 Spinal extradural hematopoiesis in adolescents with thalassemia Childs Nerv Syst 7 223 225 10.1007/BF00249400 1:STN:280:DyaK38%2FjsVOqsQ%3D%3D 1933920
25. K Abbassioun A Amir-Jamshidi 1982 Curable paraplegia due to extradural hematopoietic tissue in thalassemia Neurosurgery 11 804 807 10.1227/00006123- 198212000-00017 1:STN:280:DyaL3s7ktF2qsQ%3D%3D 7162576
26. K Parsa A Oreizy 1995 Nonsurgical approach to paraparesis due to extramedullary hematopoiesis J Neurosurg 82 657 660 1:STN:280: DyaK2M3gsFakuw%3D%3D 7897533
27. S Singhal S Sharma S Dixit S De S Chander GK Rath VS Mehta 1992 The role of radiation therapy in the management of spinal cord compression due to extramedullary hematopoiesis in thalassemia J Neurol Neurosurg Psychiatry 55 310 312 10.1136/jnnp.55.4.310 1:STN:280:DyaK383mtVamsA%3D%3D 1583517
28. W Luyendjik L Went HD Schaad 1975 Spinal cord compression due to extramedullary hematopoiesis in homozygous thalassemia: case report J Neurosurg 42 212 216 10.3171/jns.1975.42.2.0212
29. J Logothetics M Constantoulakis J Exonomidou C Stefanis P Hakas O Augoustaki K Sofroniadou R Loewenson M Bilek 1972 Thalassaemia major (homozygous eta thalassemia). A survery of 138 cases with emphasis on neurologic and muscular aspects Neurology 22 249 304
30. S Prabhakar J Chopra VK Khosla S Dash AK Banerijee 1980 Spinal compression in homozygous beta thalassemia Surg Neurol 13 351 354 1:STN:280:DyaL3c3hsVaisQ%3D%3D 7385000
31. KH Shin S Sharma SJ Gregoritch RM Lifeso R Bettigole SS Yoon 1994 Combined radiotherapeutic and surgical management of a spinal cord compression by extramedullary hematopoiesis in a patient with hemoglobin E beta thalassemia Acta Haematol 91 154 157 10.1159/000204322 1:STN:280:DyaK2cznvVyjsg%3D%3D 8091937
32. I Gatto V Terrana L Biondi 1954 Compression of the spinal cord due to proliferation of bone marrow in epidural space in a splenectomized person with Cooley's disease Haematologica 38 61 75 1:STN:280:DyaG2c%2FntFCrsw%3D%3D 13151530
33. JN Cross OS Morgan WN Gibbs I Cheruvanky 1977 Spinal cord compression in thalassaemia J Neurol Neurosurg Psychiatry 40 1120 1122 10.1136/jnnp.40.11.1120 1:STN:280:DyaE1c%2FovVOgsQ%3D%3D 599359
34. S Issargisil A Piankijagum W Prawase 1981 Spinal cord compression in thalassemia. Report of 12 cases and recommendations for treatment Arch Intern Med 141 1033 1036 10.1001/archinte.141.8.1033 (Pubitemid 11067840)
35. WF Luitjes R Braakman J Abels 1982 Spinal cord compression in a new homozygous variant of beta-thalassemia. Case report J Neurosurg 57 846 848 10.3171/jns.1982.57.6.0846 1:STN:280:DyaL3s%2FlvV2itg%3D%3D 7143072
36. CV David P Balasubramaniam 1983 Paraplegia with thalassemia Aust NZ J Surg 53 283 284 10.1111/j.1445-2197.1983.tb02446.x 1:STN:280: DyaL3s3ot1Gjtg%3D%3D
37. C Papavasiliou P Sandilos 1987 Effect of radiotherapy in symptoms due to heterotopic marrow in beta-thalassemia Lancet 1 13 14 10.1016/S0140-6736(87) 90702-1 1:STN:280:DyaL2s%2FovVKgsg%3D%3D 2879092
38. KS Mann CP Yue KH Chan LT Ma H Ngan 1987 Paraplegia due to extramedullary hematopoiesis in thalassemia. Case report J Neurosurg 66 938 940 10.3171/jns.1987.66.6.0938 1:STN:280:DyaL2s7pslKjtA%3D%3D 3572525
39. S Issardgrisil A Piankijagum P Wasi 1987 Spinal cord compression in thalassemia Arch Intern Med 141 1033 1036 10.1001/archinte.141.8.1033
40. DV Jackson Jr ME Randall F Richards 2nd 1988 Spinal cord compression due to extramedullary hematopoiesis in thalassemia: long-term follow-up after radiotherapy Surg Neurol 29 388 392
41. MA Martinez-Rodrigo L Sanjuanbenito E Rodriguez del Barrion J Martinez-San Millan D Saldana 1988 Spinal cord compression secondary to epidural extramedullary hematopoiesis in thalassemia: a clinical case and review of literature Rev Neurol 27 998 1004
42. EG Singounas DE Sakas DM Hadley G Chalevelakis G Sfakianos S Raptis PC Karvounis 1991 Paraplegia in a pregnant thalassemic woman due to extramedullary hematopoiesis: successful management with transfusions Surg Neurol 36 210 215 10.1016/0090-3019(91)90115-P 1:STN:280:DyaK3MzksVWitQ%3D%3D 1876971
43. H Hassoun L Lawn-Tsao ER Langevin ES Lathi J Palek 1991 Spinal cord compression secondary to extramedullary hematopoiesis: a noninvasive management based on MRI Am J Hematol 37 201 203 10.1002/ajh.2830370314 1:STN:280: DyaK3MzhsVGrtQ%3D%3D 1858773
44. T Kaufmann M Coleman P Giardina LZ Nisce 1991 The role of radiation therapy in the management of hematopoietic neurologic complications in thalassemia Acta Haematol 85 156 159 10.1159/000204880 1:STN:280: DyaK3M3ltleltg%3D%3D 2042449
45. G Chaljub F Guinto W Crow R Kumar 1991 MRI diagnosis of spinal cord compression in beta thalassemia Spine 16 583 584 10.1097/00007632-199105000- 00019 1:STN:280:DyaK3M3nt1Sltg%3D%3D 2053003
46. P Mancuso A Zingale L Basile I Chiaramonte R Tropea 1993 Cauda equina compression syndrome in a patient affected by thalassemia intermedia: complete regression with blood transfusion therapy Childs Nerv Syst 9 440 441 10.1007/BF00306203 1:STN:280:DyaK2c7jvV2luw%3D%3D 8306365 (Pubitemid 24015566)
47. E Richter 1993 Extramedullary hematopoiesis with intraspinal extension in thalassemia Aktuelle Radiol 3 320 322 1:STN:280:DyaK2c%2Fgt1aqtA%3D%3D 8399424
48. F Dore S Pardini E Gaviano M Longinotti S Bonfigli S Rovasio A Tomiselli F Cossu 1993 Recurrence of spinal cord compression from extramedullary hematopoiesis in thalassemia intermedia treated with low doses of radiotherapy Am J Hematol 44 148 10.1002/ajh.2830440216 1:STN:280:DyaK2c%2FptFartQ%3D%3D 8266922
49. SR Lau O Chan Y Chow 1994 Cord compression due to extramedullary hematopoiesis in a patient with thalassemia Spine 19 2467 2470 10.1097/00007632-199411000-00019 1:STN:280:DyaK2M7kvFajtA%3D%3D 7846603
50. AD Gouliamos GA Plataniotis ES Michalopoulos LS Vlahos CG Papavasiliou 1995 Magnetic resonance imaging spinal cord compression in thalassaemia before and after radiation treatment Clin Radiol 50 504 505 10.1016/S0009-9260(05) 83173-3 1:STN:280:DyaK2MzjvFKrsw%3D%3D 7614803
51. AC Lee W Chiu KS Tai V Wong WC Pech YL Lau 1996 Hypertransfusion for spinal cord compression secondary to extramedullary haematopoiesis Pediatr Hematol Oncol 13 89 94 10.3109/08880019609033375 1:STN:280:DyaK28zktlSitA%3D%3D 8718506
52. K Pistevou Gompaki G Skaragas P Papaskevopoulos K Kotsa E Repanta 1996 Extramedullary hematopoiesis in thalassemia, results of radiotherapy: a report of three patients Clin Oncol 8 120 122 10.1016/S0936-6555(96)80120-8 1:STN:280:DyaK2s%2Fht1OktA%3D%3D (Pubitemid 26139013)
53. P Cianciulli F Sorrentino L Morino A Massa GL Sergiacomi V Donato S Amadori 1996 Radiotherapy combined with erythropoietin for the treatment of extramedullary hematopoiesis in an alloimmunized patient with thalassemia intermedia Ann Hematol 72 379 381 10.1007/s002770050190 1:STN:280: DyaK28zgt1ahtw%3D%3D 8767108 (Pubitemid 26229980)
54. S BoyacIgil S Ardiç F Tokoǧlu E Pasaoǧlu HM Karakas 1996 Intrathoracic extramedullary haematopoiesis Australas Radiol 40 179 181 10.1111/j.1440-1673.1996.tb00379.x 8687357
55. E Coskun A Keskin T Suzer Y Sermez T Kildaci K Tahta 1998 Spinal cord compression secondary to extramedullary hematopoiesis in thalassemia intermedia Eur Spine J 7 501 504 10.1007/s005860050114 1:STN:280:DyaK1M%2FpvVChuw%3D%3D 9883960 (Pubitemid 29009748)
56. BR Saxon D Rees NF Olivieri 1998 Regression of extramedullary haemopoiesis and augmentation of fetal haemoglobin concentration during hydroxyurea therapy in beta thalassemia Br J Haematol 101 416 419 10.1046/j.1365-2141.1998.00719.x 1:CAS:528:DyaK1cXktVCjtL4%3D 9633880 (Pubitemid 28266931)
57. P Cianciulli TC di Toritto F Sorrentino L Sergiacomi A Massa S Amadori 2000 Hydroxyurea therapy in paraparesis and cauda equina syndrome due to extramedullary haematopoiesis in thalassaemia: improvement of clinical and haematological parameters Eur J Haematol 64 426 429 10.1034/j.1600-0609.2000. 9c165.x 1:STN:280:DC%2BD3czls1Oktw%3D%3D 10901597 (Pubitemid 30435396)
58. V Phupong B Uerpairojkij S Limpongsanurak 2000 Spinal cord compression: a rareness in pregnant thalassemic woman J Obstet Gynaecol Res 26 117 120 10.1111/j.1447-0756.2000.tb01293.x 1:STN:280:DC%2BD3czivVejuw%3D%3D 10870303
59. B Aliberti A Patrikiou A Terentiou S Frangatou A Papadimitriou 2001 Spinal cord compression due to extramedullary hematopoiesis in two patients with thalassemia: complete response with blood transfusion therapy J Neurol 248 18 22 10.1007/s004150170264 1:STN:280:DC%2BD3M7msVCksw%3D%3D 11266014 (Pubitemid 32245440)
60. D Chourmouzi K Pistevou-Gompaki G Plataniotis G Skaragas L Papadopoulos A Drevelegas 2001 MRI findings of extramedullary haemopoiesis Eur Radiol 11 1803 1806 10.1007/s003300000802 1:STN:280:DC%2BD3Mvms1CqtA%3D%3D 11511905 (Pubitemid 32821390)
61. H Cario M Wegener KM Debatin E Kohne 2002 Treatment with hydroxyurea in thalassemia intermedia with paravertebral pseudotumors of extramedullary hematopoiesis Ann Hematol 81 478 482 10.1007/s00277-002-0501-4 1:STN:280:DC%2BD38vmsVSgsw%3D%3D 12224008 (Pubitemid 36067664)
62. TC Tan J Tsao FC Cheung 2002 Extramedullary haemopoiesis in thalassemia intermedia presenting as paraplegia J Clin Neurosci 9 721 725 10.1054/jocn.2001.1038 12604297 (Pubitemid 35364758)
63. A Chehal E Aoun S Koussa H Skoury S Koussa A Taher 2003 Hypertransfusion: a successful method of treatment in thalassemia intermedia patients with spinal cord compression secondary to extramedullary hematopoiesis Spine 28 E245 E249 10.1097/00007632-200307010-00024 12838112
64. SA Salehi T Koski SL Ondra 2004 Spinal cord compression in betathalassemia: case report and review of the literature Spinal Cord 42 117 123 10.1038/sj.sc.3101544 1:STN:280:DC%2BD2c%2Fmtl2gsg%3D%3D 14765145 (Pubitemid 38250834)
65. B Zamanizadeh SS Eghbali M Taghipour A Haghnegahdar Z Zare 2006 Spinal cord compression secondary to extramedullary hematopoiesis: case report and summary Neurosurg Q 16 144 146 10.1097/01.wnq.0000214020.57539.46 (Pubitemid 44351122)
66. M Malik LS Pillai N Gogia T Puri M Mahapatra DN Sharma R Kumar 2007 Paraplegia due to extramedullary hematopoiesis in thalassemia treated successfully with radiation therapy Haematologica 92 e28 e30 10.3324/haematol.10199 17405752
67. M Goerner S Gerull E Schaefer M Just M Sure P Hirnle 2008 Painful spinal cord compression as a complication of extramedullary hematopoiesis associated with β-thalassemia intermedia Strahlenther Onkol 4 224 226 10.1007/s00066-008-1794-6 (Pubitemid 351508130)
68. B Moncef J Hafedh 2008 Management of spinal cord compression caused by extramedullary hematopoiesis in beta-thalassemia Inter Med 47 1125 1128 10.2169/internalmedicine.47.0890
69. T Ileri F Azik M Ertem Z Uysal S Gozdasoglu 2009 Extramedullary hematopoiesis with spinal cord compression in a child with thalassemia intermedia J Pediatr Hematol Oncol 31 681 683 10.1097/MPH.0b013e3181a71843 19687759
70. Fetell MR, Stein BM (1989) Spinal tumors. In: Rowland LP (ed) Merritt's textbook of neurology, 8th edn. Lea & Febiger, Philadelphia, pp 350-364
71. DA Dibbern LA Loevner AP Lieberman KE Salhany A Freese PJ Marcotte 1997 MR of thoracic cord compression caused by epidural extramedullary hematopoiesis in myelodysplastic syndrome AJNR Am J Neuroradiol 18 363 366 9111677
72. O Sorsdahl PE Taylor WD Noyes 1964 Extramedullary hematopoiesis, mediastinal masses and spinal cord compression JAMA 189 343 347 1:STN:280:DyaF2c7hvVCktQ%3D%3D 14160505
73. LJ Bronn JR Paquelet MR Tetalman 1980 Intrathoracic extramedullary hematopoiesis: appearance on 99mTc sulfur colloid marrow scan AJR Am J Roentgenol 134 1254 1255 1:STN:280:DyaL3c3hslamtg%3D%3D 6770640
74. MB Oustwani ES Kurtides M Christ I Ciric 1980 Spinal cord compression with paraplegia in myelofibrosis Arch Neurol 37 389 390 1:STN:280: DyaL3c3hvFOmsQ%3D%3D 7387474
75. A Guermazi Y Miaux J Chiras 1997 Imaging of spinal cord compression due to thoracic extramedullary haematopoiesis in myelofibrosis Neuroradiology 39 733 736 10.1007/s002340050497 1:STN:280:DyaK1c%2Fht1ersA%3D%3D 9351112 (Pubitemid 27425069)
76. P Kalina W Zaheer KE Drehobl 1995 Cord compression by extramedullary hematopoesis in polycythemia vera AJR Am J Roentgenol 164 1027 1028 1:STN:280:DyaK2M3ktlSrtg%3D%3D 7726026
77. IJ Wolman M Ortolani 1969 Some clinical features of Cooley's anemia patients as related to transfusion schedules Ann N Y Acad Sci 165 407 414 10.1111/j.1749-6632.1969.tb27811.x 1:STN:280:DyaE3c%2FjtFGktg%3D%3D 5260163
78. J Lawson R Ablow H Pearson 1981 The ribs in thalassemia. I the Relationship to therapy Radiology 140 663 672 1:STN:280:DyaL38%2Fhs1agtQ%3D%3D 7280233
79. M Yamato C Fuhrman 1987 Computed tomography of fatty replacement in extramedullary hematopoiesis J Comput Assisted Tomogr 11 541 542 10.1097/00004728-198705000-00036 1:STN:280:DyaL2s7psFKnsA%3D%3D
80. S Savader R Otero B Savader 1988 MR imaging of intrathoracic extramedullary hematopoiesis J Comput Assist Tomogr 12 878 880 10.1097/00004728-198809010-00032 1:STN:280:DyaL1M%2FgvFSruw%3D%3D 3170852
81. B Mesurolle E Sayag P Meingan P Lasser P Duvillard D Vanel 1996 Retroperitoneal extramedullary hematopoiesis: sonographic, CT and MR imaging appearance AJR Am J Roentgenol 167 1139 1140 1:STN:280:DyaK2s%2Fmslygug%3D%3D 8911166
82. N De Klippel MF Dehou C Bourgain R Schots J De Keyser G Ebinger 1993 Progressive paraparesis due to thoracic extramedullary hematopoiesis in myelofibrosis. Case report J Neurosurg 79 125 127 10.3171/jns.1993.79.1.0125 8315451
83. SM Tai JS Chan SY Ha BW Young MS Chan 2006 Successful treatment of spinal cord compression secondary to extramedullary hematopoietic mass by hypertransfusion in a patient with thalassemia major Pediatr Hematol Oncol 23 317 321 10.1080/08880010600629676 1:STN:280:DC%2BD283hsFOrsQ%3D%3D 16621773
84. T Bolling A Schuck C Rube S Hesselmann H Pape K Dieckmann B Pöllinger RD Kortmann I Speiser-Held FM Meyer C Martini B Asadpour B Timmermann JD Beck T Langer M Paulides B Schmidt N Willich 2006 Therapy-associated late effects after irradiation of malignant diseases in childhood and adolescence, Feasibility analyses of a prospective multicenter register study Strahlenther Onkol 182 443 449 10.1007/s00066-006-1517-9 16896590 (Pubitemid 44214487)
85. D Rades J Dahm-Daphi V Rudat R Schulte LJ Stalpers T Veninga PJ Hoskin 2006 Is short-course radiotherapy with high doses per fraction the appropriate regimen for metastatic spinal cord compression in colorectal cancer patients? Strahlenther Onkol 182 708 712 10.1007/s00066-006-1578-9 17149577 (Pubitemid 44887172)
86. KR Trott F Kamprad 2006 Estimation of cancer risks from radiotherapy of benign diseases Strahlenther Onkol 182 431 436 10.1007/s00066-006-1542-8 16896588 (Pubitemid 44214485)
87. NF Olivieri DC Rees GD Ginder SL Thein GM Brittenham JS Waye DJ Weatherall 1997 Treatment of thalassemia major with phenylbutyrate and hydroxyurea Lancet 350 491 492 10.1016/S0140-6736(05)63080-2 1:CAS:528:DyaK2sXlvVKhsLw%3D 9274590 (Pubitemid 27343309)
88. K Konstantopoulos G Vagiopoulos R Kantouni S Lymperi G Patriarcheas D Georgakopoulos P Fessas 1922 A case of spinal cord compression by extramedullary haematopoiesis in a thalassaemia patient: a putative role for hydroxyurea? Haematologica 77 352 354