메뉴 건너뛰기




Volumn 42, Issue 4, 2014, Pages 791-797

Approaches for measuring signalling plasticity in the context of resistance to targeted cancer therapies

Author keywords

Acquired resistance; Cancer; Mass spectrometry; Phosphoproteomics; Signalling plasticity; Systems biology

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; STAT5 PROTEIN; ANTINEOPLASTIC AGENT; PHOSPHOPROTEIN;

EID: 84905861302     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20140029     Document Type: Conference Paper
Times cited : (5)

References (50)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D. and Weinberg, R.A. (2011) Hallmarks of cancer: the next generation. Cell 144, 646-674
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 81155151860 scopus 로고    scopus 로고
    • The BCR-ABL(35INS) insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia
    • O'Hare, T., Zabriskie, M.S., Eide, C.A., Agarwal, A., Adrian, L.T., You, H., Corbin, A.S., Yang, F., Press, R.D., Rivera, V.M. et al. (2011) The BCR-ABL(35INS) insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia. Blood 118, 5250-5254
    • (2011) Blood , vol.118 , pp. 5250-5254
    • O'hare, T.1    Zabriskie, M.S.2    Eide, C.A.3    Agarwal, A.4    Adrian, L.T.5    You, H.6    Corbin, A.S.7    Yang, F.8    Press, R.D.9    Rivera, V.M.10
  • 3
    • 79953713970 scopus 로고    scopus 로고
    • Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome-positive acute lymphoblastic leukemia
    • Boulos, N., Mulder, H.L., Calabrese, C.R., Morrison, J.B., Rehg, J.E., Relling, M.V., Sherr, C.J. and Williams, R.T. (2011) Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood 117, 3585-3595
    • (2011) Blood , vol.117 , pp. 3585-3595
    • Boulos, N.1    Mulder, H.L.2    Calabrese, C.R.3    Morrison, J.B.4    Rehg, J.E.5    Relling, M.V.6    Sherr, C.J.7    Williams, R.T.8
  • 10
    • 84863596086 scopus 로고    scopus 로고
    • MEK inhibition leads to PI3K/AKT activation by relieving a negative feedback on ERBB receptors
    • Turke, A.B., Song, Y., Costa, C., Cook, R., Arteaga, C.L., Asara, J.M. and Engelman, J.A. (2012) MEK inhibition leads to PI3K/AKT activation by relieving a negative feedback on ERBB receptors. Cancer Res. 72, 3228-3237
    • (2012) Cancer Res. , vol.72 , pp. 3228-3237
    • Turke, A.B.1    Song, Y.2    Costa, C.3    Cook, R.4    Arteaga, C.L.5    Asara, J.M.6    Engelman, J.A.7
  • 13
    • 84870825008 scopus 로고    scopus 로고
    • JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: A rationale for cotargeting these pathways in metastatic breast cancer
    • Britschgi, A., Andraos, R., Brinkhaus, H., Klebba, I., Romanet, V., Mueller, U., Murakami, M., Radimerski, T. and Bentires-Alj, M. (2012) JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: a rationale for cotargeting these pathways in metastatic breast cancer. Cancer Cell 22, 796-811
    • (2012) Cancer Cell , vol.22 , pp. 796-811
    • Britschgi, A.1    Andraos, R.2    Brinkhaus, H.3    Klebba, I.4    Romanet, V.5    Mueller, U.6    Murakami, M.7    Radimerski, T.8    Bentires-Alj, M.9
  • 15
    • 4544369383 scopus 로고    scopus 로고
    • Forkhead box transcription factor FOXO3a regulates estrogen receptor expression and is repressed by the Her-2/neu/phosphatidylinositol 3-kinase/Akt signaling pathway
    • Guo, S.Q. and Sonenshein, G.E. (2004) Forkhead box transcription factor FOXO3a regulates estrogen receptor expression and is repressed by the Her-2/neu/phosphatidylinositol 3-kinase/Akt signaling pathway. Mol. Cell. Biol. 24, 8681-8690
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 8681-8690
    • Guo, S.Q.1    Sonenshein, G.E.2
  • 20
    • 84862777672 scopus 로고    scopus 로고
    • A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
    • Ng, K.P., Hillmer, A.M., Chuah, C.T.H., Juan, W.C., Ko, T.K., Teo, A.S.M., Ariyaratne, P.N., Takahashi, N., Sawada, K., Fei, Y. et al. (2012) A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer. Nat. Med. 18, 521-528
    • (2012) Nat. Med. , vol.18 , pp. 521-528
    • Ng, K.P.1    Hillmer, A.M.2    Chuah, C.T.H.3    Juan, W.C.4    Ko, T.K.5    Teo, A.S.M.6    Ariyaratne, P.N.7    Takahashi, N.8    Sawada, K.9    Fei, Y.10
  • 21
    • 0001686739 scopus 로고    scopus 로고
    • Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
    • Shah, N.P., Nicoll, J.M., Nagar, B., Gorre, M.E., Paquette, R.L., Kuriyan, J. and Sawyers, C.L. (2002) Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell 2, 117-125
    • (2002) Cancer Cell , vol.2 , pp. 117-125
    • Shah, N.P.1    Nicoll, J.M.2    Nagar, B.3    Gorre, M.E.4    Paquette, R.L.5    Kuriyan, J.6    Sawyers, C.L.7
  • 22
    • 0035800507 scopus 로고    scopus 로고
    • Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
    • Gorre, M.E., Mohammed, M., Ellwood, K., Hsu, N., Paquette, R., Rao, P.N. and Sawyers, C.L. (2001) Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 293, 876-880
    • (2001) Science , vol.293 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3    Hsu, N.4    Paquette, R.5    Rao, P.N.6    Sawyers, C.L.7
  • 25
    • 84856717005 scopus 로고    scopus 로고
    • Identification of a mutation in the extracellular domain of the epidermal growth factor receptor conferring cetuximab resistance in colorectal cancer
    • Montagut, C., Dalmases, A., Bellosillo, B., Crespo, M., Pairet, S., Iglesias, M., Salido, M., Gallen, M., Marsters, S., Tsai, S.P. et al. (2012) Identification of a mutation in the extracellular domain of the epidermal growth factor receptor conferring cetuximab resistance in colorectal cancer. Nat. Med. 18, 221-223
    • (2012) Nat. Med. , vol.18 , pp. 221-223
    • Montagut, C.1    Dalmases, A.2    Bellosillo, B.3    Crespo, M.4    Pairet, S.5    Iglesias, M.6    Salido, M.7    Gallen, M.8    Marsters, S.9    Tsai, S.P.10
  • 33
    • 80053070033 scopus 로고    scopus 로고
    • PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis
    • Ilic, N., Utermark, T., Widlund, H.R. and Roberts, T.M. (2011) PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis. Proc. Natl. Acad. Sci. U.S.A. 108, E699-E708
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108
    • Ilic, N.1    Utermark, T.2    Widlund, H.R.3    Roberts, T.M.4
  • 42
    • 84885957225 scopus 로고    scopus 로고
    • Genome-based cancer therapeutics: Targets, kinase drug resistance and future strategies for precision oncology
    • Workman, P., Al-Lazikani, B. and Clarke, P.A. (2013) Genome-based cancer therapeutics: targets, kinase drug resistance and future strategies for precision oncology. Curr. Opin. Pharmacol. 13, 486-496
    • (2013) Curr. Opin. Pharmacol. , vol.13 , pp. 486-496
    • Workman, P.1    Al-Lazikani, B.2    Clarke, P.A.3
  • 43
    • 74049122828 scopus 로고    scopus 로고
    • Cancer systems biology: A network modeling perspective
    • Kreeger, P.K. and Lauffenburger, D.A. (2010) Cancer systems biology: a network modeling perspective. Carcinogenesis 31, 2-8
    • (2010) Carcinogenesis , vol.31 , pp. 2-8
    • Kreeger, P.K.1    Lauffenburger, D.A.2
  • 44
    • 79952635505 scopus 로고    scopus 로고
    • Principles and strategies for developing network models in cancer
    • Pe'er, D. and Hacohen, N. (2011) Principles and strategies for developing network models in cancer. Cell 144, 864-873
    • (2011) Cell , vol.144 , pp. 864-873
    • Pe'er, D.1    Hacohen, N.2
  • 45
    • 84870390823 scopus 로고    scopus 로고
    • Global profiling of protein kinase activities in cancer cells by mass spectrometry
    • Beltran, L., Casado, P., Rodriguez-Prados, J.-C. and Cutillas, P.R. (2012) Global profiling of protein kinase activities in cancer cells by mass spectrometry. J. Proteomics 77, 492-503
    • (2012) J. Proteomics , vol.77 , pp. 492-503
    • Beltran, L.1    Casado, P.2    Rodriguez-Prados, J.-C.3    Cutillas, P.R.4
  • 46
  • 49
    • 84864803277 scopus 로고    scopus 로고
    • Phosphoproteomic analysis of leukemia cells under basal and drug-treated conditions identifies markers of kinase pathway activation and mechanisms of resistance
    • Alcolea, M.P., Casado, P., Rodriguez-Prados, J.C., Vanhaesebroeck, B. and Cutillas, P.R. (2012) Phosphoproteomic analysis of leukemia cells under basal and drug-treated conditions identifies markers of kinase pathway activation and mechanisms of resistance. Mol. Cell. Proteomics 11, 453-466
    • (2012) Mol. Cell. Proteomics , vol.11 , pp. 453-466
    • Alcolea, M.P.1    Casado, P.2    Rodriguez-Prados, J.C.3    Vanhaesebroeck, B.4    Cutillas, P.R.5
  • 50
    • 79951523091 scopus 로고    scopus 로고
    • Biological signalling activity measurements using mass spectrometry
    • Cutillas, P.R. and Jorgensen, C. (2011) Biological signalling activity measurements using mass spectrometry. Biochem. J. 434, 189-199
    • (2011) Biochem. J. , vol.434 , pp. 189-199
    • Cutillas, P.R.1    Jorgensen, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.