Monoamine oxidase inhibition prevents mitochondrial dysfunction and apoptosis in myoblasts from patients with collagen VI myopathies

Free Radical Biology and Medicine

Volumn 75, Issue , 2014, Pages 40-47

  Sorato, E ^a   Menazza, S ^a   Zulian, A ^a   Sabatelli, P ^b   Gualandi, F ^c   Merlini, L ^d   Bonaldo, P ^a   Canton, M ^a   Bernardi, P ^a,b   Di Lisa, F ^a,b  

^a UNIVERSITY OF PADOVA   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF FERRARA   (Italy)

^d RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

Author keywords

Cell death; Mitochondria; Monoamine oxidases; Muscular dystrophy; Oxidative stress

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; COLLAGEN TYPE 6; HYDROGEN PEROXIDE; MONOAMINE OXIDASE INHIBITOR; PARGYLINE; REACTIVE OXYGEN METABOLITE; TYRAMINE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME INHIBITION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HUMAN TISSUE; INCUBATION TIME; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; MUSCLE BIOPSY; MUSCULAR DYSTROPHY; MYOBLAST; MYOPATHY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; ADULT; BIOSYNTHESIS; CELL CULTURE; CHILD; DRUG EFFECTS; ENZYMOLOGY; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY; PRESCHOOL CHILD; BETHLEM MYOPATHY; BIOACCUMULATION; ULLRICH CONGENITAL MUSCULAR DYSTROPHY; UPREGULATION;

ADULT; APOPTOSIS; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; COLLAGEN TYPE VI; HUMANS; HYDROGEN PEROXIDE; MITOCHONDRIA; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; MUSCULAR DYSTROPHIES; MYOBLASTS; OXIDATIVE STRESS; PARGYLINE; TYRAMINE;

EID: 84905851916     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.07.006     Document Type: Article

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