Critical evaluation of the use of cell cultures for inclusion in clinical trials of patients affected by collagen VI myopathies

Journal of Cellular Physiology

Volumn 227, Issue 7, 2012, Pages 2927-2935

  Sabatelli, P ^a   Palma, E ^b   Angelin, A ^b   Squarzoni, S ^a   Urciuolo, A ^b   Pellegrini, C ^c   Tiepolo, T ^b   Bonaldo, P ^b   Gualandi, F ^c   Merlini, L ^c,d   Bernardi, P ^b   Maraldi, N M ^d,e  

^a CNR   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c UNIVERSITY OF FERRARA   (Italy)

^d RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^e UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; COLLAGEN TYPE 6; CYCLOSPORIN A; DESMIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; TETRAMETHYLRHODAMINE METHYL ESTER;

ARTICLE; BETHLEM MYOPATHY; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; DEPOLARIZATION; DISEASE COURSE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MITOCHONDRIAL MEMBRANE POTENTIAL; MUSCLE CELL; MUSCLE MITOCHONDRION; MYOPATHY; MYOSCLEROSIS MYOPATHY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT RESPONSE; ULLRICH CONGENITAL MUSCULAR DYSTROPHY;

ADOLESCENT; ADULT; APOPTOSIS; CELLS, CULTURED; CHILD; CLINICAL TRIALS AS TOPIC; COLLAGEN TYPE VI; CONTRACTURE; FIBROBLASTS; HUMANS; MIDDLE AGED; MITOCHONDRIA; MUSCLE, SKELETAL; MUSCULAR DISEASES; MUSCULAR DYSTROPHIES; OUTCOME ASSESSMENT (HEALTH CARE); PATIENT SELECTION; PHENOTYPE; PRIMARY CELL CULTURE; SCLEROSIS;

EID: 84858625921     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.23039     Document Type: Article

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