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Volumn 27, Issue 8, 2014, Pages 1024-1032

Actions of circulating angiotensin II and aldosterone in the brain contributing to hypertension

Author keywords

Aldosterone; Angiotensin II; Blood pressure; Brain; Hypertension; Sympathetic activity

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ALDOSTERONE; ANGIOTENSIN II;

EID: 84905837165     PISSN: 08957061     EISSN: 19417225     Source Type: Journal    
DOI: 10.1093/ajh/hpu066     Document Type: Article
Times cited : (54)

References (88)
  • 2
    • 79955473943 scopus 로고    scopus 로고
    • Chronic lowering of blood pressure by carotid baroreflex activation: Mechanisms and potential for hypertension therapy
    • Lohmeier TE, Iliescu R. Chronic lowering of blood pressure by carotid baroreflex activation: mechanisms and potential for hypertension therapy. Hypertension 2011; 57: 880-886.
    • (2011) Hypertension , vol.57 , pp. 880-886
    • Lohmeier, T.E.1    Iliescu, R.2
  • 3
    • 79961189578 scopus 로고    scopus 로고
    • Baroreflex activation therapy lowers blood pressure in patients with resistant hypertension: Results from the double-blind, randomized, placebo-controlled rheos pivotal trial
    • Bisognano JD, Bakris G, Nadim MK, Sanchez L, Kroon AA, Schafer J, de Leeuw PW, Sica DA. Baroreflex activation therapy lowers blood pressure in patients with resistant hypertension: results from the double-blind, randomized, placebo-controlled rheos pivotal trial. J Am Coll Cardiol 2011; 58: 765-773.
    • (2011) J Am Coll Cardiol , vol.58 , pp. 765-773
    • Bisognano, J.D.1    Bakris, G.2    Nadim, M.K.3    Sanchez, L.4    Kroon, A.A.5    Schafer, J.6    De Leeuw, P.W.7    Sica, D.A.8
  • 4
    • 84865448503 scopus 로고    scopus 로고
    • Renal responses to chronic suppression of central sympathetic outflow
    • Iliescu R, Irwin ED, Georgakopoulos D, Lohmeier TE. Renal responses to chronic suppression of central sympathetic outflow. Hypertension 2012; 60: 749-756.
    • (2012) Hypertension , vol.60 , pp. 749-756
    • Iliescu, R.1    Irwin, E.D.2    Georgakopoulos, D.3    Lohmeier, T.E.4
  • 5
    • 0027196305 scopus 로고
    • Hypothalamic angiotensin release in response to aii or glutamic acid stimulation of the sfo in rats
    • Wright JW, Roberts KA, Stubley LA, Hanesworth JM, Harding JW. Hypothalamic angiotensin release in response to AII or glutamic acid stimulation of the SFO in rats. Brain Res Bull 1993; 31: 649-654.
    • (1993) Brain Res Bull , vol.31 , pp. 649-654
    • Wright, J.W.1    Roberts, K.A.2    Stubley, L.A.3    Hanesworth, J.M.4    Harding, J.W.5
  • 6
    • 16644400212 scopus 로고    scopus 로고
    • Angiotensin ii excites paraventricular nucleus neurons that innervate the rostral ventrolateral medulla: An in vitro patch-clamp study in brain slices
    • Cato MJ, Toney GM. Angiotensin II excites paraventricular nucleus neurons that innervate the rostral ventrolateral medulla: an in vitro patch-clamp study in brain slices. J Neurophysiol 2005; 93: 403-413.
    • (2005) J Neurophysiol , vol.93 , pp. 403-413
    • Cato, M.J.1    Toney, G.M.2
  • 7
    • 0038452698 scopus 로고    scopus 로고
    • Angiotensin ii stimulates spinally projecting paraventricular neurons through presynaptic disinhibition
    • Li DP, Chen SR, Pan HL. Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition. J Neurosci 2003; 23: 5041-5049.
    • (2003) J Neurosci , vol.23 , pp. 5041-5049
    • Li, D.P.1    Chen, S.R.2    Pan, H.L.3
  • 8
    • 33747383910 scopus 로고    scopus 로고
    • Nox2 ca2+ and protein kinase c play a role in angiotensin ii-induced free radical production in nucleus tractus solitarius
    • Wang G, Anrather J, Glass MJ, Tarsitano MJ, Zhou P, Frys KA, Pickel VM, Iadecola C. Nox2, Ca2+, and protein kinase C play a role in angiotensin II-induced free radical production in nucleus tractus solitarius. Hypertension 2006; 48: 482-489.
    • (2006) Hypertension , vol.48 , pp. 482-489
    • Wang, G.1    Anrather, J.2    Glass, M.J.3    Tarsitano, M.J.4    Zhou, P.5    Frys, K.A.6    Pickel, V.M.7    Iadecola, C.8
  • 9
    • 3343005248 scopus 로고    scopus 로고
    • Hypertension caused by angiotensin ii infusion involves increased superoxide production in the central nervous system
    • Zimmerman MC, Lazartigues E, Sharma RV, Davisson RL. Hypertension caused by angiotensin II infusion involves increased superoxide production in the central nervous system. Circ Res 2004; 95: 210-216.
    • (2004) Circ Res , vol.95 , pp. 210-216
    • Zimmerman, M.C.1    Lazartigues, E.2    Sharma, R.V.3    Davisson, R.L.4
  • 10
    • 0032963538 scopus 로고    scopus 로고
    • Angiotensin ii type 1 receptor-modulated signaling pathways in neurons
    • Richards EM, Raizada MK, Gelband CH, Sumners C. Angiotensin II type 1 receptor-modulated signaling pathways in neurons. Mol Neurobiol 1999; 19: 25-41.
    • (1999) Mol Neurobiol , vol.19 , pp. 25-41
    • Richards, E.M.1    Raizada, M.K.2    Gelband, C.H.3    Sumners, C.4
  • 11
    • 62949101948 scopus 로고    scopus 로고
    • Nadph oxidases and angiotensin ii receptor signaling
    • Garrido AM, Griendling KK. NADPH oxidases and angiotensin II receptor signaling. Mol Cell Endocrinol 2009; 302: 148-158.
    • (2009) Mol Cell Endocrinol , vol.302 , pp. 148-158
    • Garrido, A.M.1    Griendling, K.K.2
  • 12
    • 34249865672 scopus 로고    scopus 로고
    • Signaling mechanisms of angiotensin ii-induced attenuation of gabaergic input to hypothalamic presympathetic neurons
    • Chen Q, Pan HL. Signaling mechanisms of angiotensin II-induced attenuation of GABAergic input to hypothalamic presympathetic neurons. J Neurophysiol 2007; 97: 3279-3287.
    • (2007) J Neurophysiol , vol.97 , pp. 3279-3287
    • Chen, Q.1    Pan, H.L.2
  • 13
    • 19444362091 scopus 로고    scopus 로고
    • Angiotensin ii attenuates synaptic gaba release and excites paraventricular-rostral ventrolateral medulla output neurons
    • Li DP, Pan HL. Angiotensin II attenuates synaptic GABA release and excites paraventricular-rostral ventrolateral medulla output neurons. J Pharmacol Exp Ther 2005; 313: 1035-1045.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 1035-1045
    • Li, D.P.1    Pan, H.L.2
  • 14
    • 0031964280 scopus 로고    scopus 로고
    • Central amino acids mediate cardiovascular response to angiotensin ii in the rat
    • Zhu DN, Moriguchi A, Mikami H, Higaki J, Ogihara T. Central amino acids mediate cardiovascular response to angiotensin II in the rat. Brain Res Bull 1998; 45: 189-197.
    • (1998) Brain Res Bull , vol.45 , pp. 189-197
    • Zhu, D.N.1    Moriguchi, A.2    Mikami, H.3    Higaki, J.4    Ogihara, T.5
  • 16
    • 77955462845 scopus 로고    scopus 로고
    • Central neuronal activation and pressor responses induced by circulating ang ii: Role of the brain aldosterone-"ouabain" pathway
    • Huang BS, Ahmadi S, Ahmad M, White RA, Leenen FH. Central neuronal activation and pressor responses induced by circulating ANG II: role of the brain aldosterone-"ouabain" pathway. Am J Physiol 2010; 299: H422-H430.
    • (2010) Am J Physiol , vol.299
    • Huang, B.S.1    Ahmadi, S.2    Ahmad, M.3    White, R.A.4    Leenen, F.H.5
  • 18
    • 84856090864 scopus 로고    scopus 로고
    • Sensitization of slow pressor angiotensin ii (ang ii)-initiated hypertension: Induction of sensitization by prior ang ii treatment
    • Xue B, Zhang Z, Johnson RF, Johnson AK. Sensitization of slow pressor angiotensin II (Ang II)-initiated hypertension: induction of sensitization by prior Ang II treatment. Hypertension 2012; 59: 459-466.
    • (2012) Hypertension , vol.59 , pp. 459-466
    • Xue, B.1    Zhang, Z.2    Johnson, R.F.3    Johnson, A.K.4
  • 19
    • 0042315402 scopus 로고    scopus 로고
    • Regulation of aldosterone synthase gene expression in the rat adrenal gland and central nervous system by sodium and angiotensin ii
    • Ye P, Kenyon CJ, MacKenzie SM, Seckl JR, Fraser R, Connell JM, Davies E. Regulation of aldosterone synthase gene expression in the rat adrenal gland and central nervous system by sodium and angiotensin II. Endocrinology 2003; 144: 3321-3328.
    • (2003) Endocrinology , vol.144 , pp. 3321-3328
    • Ye, P.1    Kenyon, C.J.2    MacKenzie, S.M.3    Seckl, J.R.4    Fraser, R.5    Connell, J.M.6    Davies, E.7
  • 20
    • 27844492749 scopus 로고    scopus 로고
    • Distribution of epithelial sodium channels and mineralocorticoid receptors in cardiovascular regulatory centers in rat brain
    • Amin MS, Wang HW, Reza E, Whitman SC, Tuana BS, Leenen FH. Distribution of epithelial sodium channels and mineralocorticoid receptors in cardiovascular regulatory centers in rat brain. Am J Physiol 2005; 289: R1787-R1797.
    • (2005) Am J Physiol , vol.289
    • Amin, M.S.1    Wang, H.W.2    Reza, E.3    Whitman, S.C.4    Tuana, B.S.5    Leenen, F.H.6
  • 21
    • 14544281944 scopus 로고    scopus 로고
    • Colocalization of mineralocorticoid receptor and glucocorticoid receptor in the hippocampus and hypothalamus
    • Han F, Ozawa H, Matsuda K, Nishi M, Kawata M. Colocalization of mineralocorticoid receptor and glucocorticoid receptor in the hippocampus and hypothalamus. Neurosci Res 2005; 51: 371-381.
    • (2005) Neurosci Res , vol.51 , pp. 371-381
    • Han, F.1    Ozawa, H.2    Matsuda, K.3    Nishi, M.4    Kawata, M.5
  • 22
    • 0025088301 scopus 로고
    • 11 Beta-hydroxysteroid dehydrogenase bioactivity and messenger rna expression in rat forebrain: Localization in hypothalamus, hippocampus, and cortex
    • Moisan MP, Seckl JR, Edwards CR. 11 beta-Hydroxysteroid dehydrogenase bioactivity and messenger RNA expression in rat forebrain: localization in hypothalamus, hippocampus, and cortex. Endocrinology 1990; 127: 1450-1455.
    • (1990) Endocrinology , vol.127 , pp. 1450-1455
    • Moisan, M.P.1    Seckl, J.R.2    Edwards, C.R.3
  • 23
    • 33746022627 scopus 로고    scopus 로고
    • 11beta-Hydroxysteroid dehydrogenase type 2 activity in hypothalamic paraventricular nucleus modulates sympathetic excitation
    • Zhang ZH, Kang YM, Yu Y, Wei SG, Schmidt TJ, Johnson AK, Felder RB. 11beta-Hydroxysteroid dehydrogenase type 2 activity in hypothalamic paraventricular nucleus modulates sympathetic excitation. Hypertension 2006; 48: 127-133.
    • (2006) Hypertension , vol.48 , pp. 127-133
    • Zhang, Z.H.1    Kang, Y.M.2    Yu, Y.3    Wei, S.G.4    Schmidt, T.J.5    Johnson, A.K.6    Felder, R.B.7
  • 24
    • 84899428268 scopus 로고    scopus 로고
    • Expression of mineralocorticoid and glucocorticoid receptors in preautonomic neurons of the rat paraventricular nucleus
    • Chen J, Gomez-Sanchez CE, Penman A, May PJ, Gomez-Sanchez E. Expression of mineralocorticoid and glucocorticoid receptors in preautonomic neurons of the rat paraventricular nucleus. Am J Physiol 2014; 306: R328-R340.
    • (2014) Am J Physiol , vol.306
    • Chen, J.1    Gomez-Sanchez, C.E.2    Penman, A.3    May, P.J.4    Gomez-Sanchez, E.5
  • 25
    • 77954351476 scopus 로고    scopus 로고
    • Blockade of mineralocorticoid receptors improves salt-induced left-ventricular systolic dysfunction through attenuation of enhanced sympathetic drive in mice with pressure overload
    • Ito K, Hirooka Y, Sunagawa K. Blockade of mineralocorticoid receptors improves salt-induced left-ventricular systolic dysfunction through attenuation of enhanced sympathetic drive in mice with pressure overload. J Hypertens 2010; 28: 1449-1458.
    • (2010) J Hypertens , vol.28 , pp. 1449-1458
    • Ito, K.1    Hirooka, Y.2    Sunagawa, K.3
  • 26
    • 84887603517 scopus 로고    scopus 로고
    • Enacexpressing neurons in the sensory circumventricular organs become c-fos activated following systemic sodium changes
    • Miller RL, Wang MH, Gray PA, Salkoff LB, Loewy AD. ENaCexpressing neurons in the sensory circumventricular organs become c-Fos activated following systemic sodium changes. Am J Physiol 2013; 305: R1141-R1152.
    • (2013) Am J Physiol , vol.305
    • Miller, R.L.1    Wang, M.H.2    Gray, P.A.3    Salkoff, L.B.4    Loewy, A.D.5
  • 27
    • 84856144688 scopus 로고    scopus 로고
    • Epithelial na sodium channels in magnocellular cells of the rat supraoptic and paraventricular nuclei
    • Teruyama R, Sakuraba M, Wilson LL, Wandrey NE, Armstrong WE. Epithelial Na sodium channels in magnocellular cells of the rat supraoptic and paraventricular nuclei. Am J Physiol 2012; 302: E273-E285.
    • (2012) Am J Physiol , vol.302
    • Teruyama, R.1    Sakuraba, M.2    Wilson, L.L.3    Wandrey, N.E.4    Armstrong, W.E.5
  • 28
    • 0026729405 scopus 로고
    • Distribution of the endogenous digitalis-like substance (edls)-containing neurons labeled by digoxin antibody in hypothalamus and three circumventricular organs of dog and macaque
    • Yamada H, Ihara N, Takahashi H, Yoshimura M, Sano Y. Distribution of the endogenous digitalis-like substance (EDLS)-containing neurons labeled by digoxin antibody in hypothalamus and three circumventricular organs of dog and macaque. Brain Res 1992; 584: 237-243.
    • (1992) Brain Res , vol.584 , pp. 237-243
    • Yamada, H.1    Ihara, N.2    Takahashi, H.3    Yoshimura, M.4    Sano, Y.5
  • 30
    • 79960350166 scopus 로고    scopus 로고
    • An ouabain-like factor is secreted from immortalized hypothalamic cells in an aldosteronedependent manner
    • Yoshika M, Komiyama Y, Takahashi H. An ouabain-like factor is secreted from immortalized hypothalamic cells in an aldosteronedependent manner. Neurochem Int 2011; 59: 104-108.
    • (2011) Neurochem Int , vol.59 , pp. 104-108
    • Yoshika, M.1    Komiyama, Y.2    Takahashi, H.3
  • 31
    • 0344440820 scopus 로고    scopus 로고
    • Brain sodium channels and ouabainlike compounds mediate central aldosterone-induced hypertension
    • Wang H, Huang BS, Leenen FH. Brain sodium channels and ouabainlike compounds mediate central aldosterone-induced hypertension. Am J Physiol 2003; 285: H2516-H2523.
    • (2003) Am J Physiol , vol.285
    • Wang, H.1    Huang, B.S.2    Leenen, F.H.3
  • 32
    • 80052862388 scopus 로고    scopus 로고
    • Regulation of hypothalamic renin-angiotensin system and oxidative stress by aldosterone
    • Huang BS, Zheng H, Tan J, Patel KP, Leenen FH. Regulation of hypothalamic renin-angiotensin system and oxidative stress by aldosterone. Exp Physiol 2011; 96: 1028-1038.
    • (2011) Exp Physiol , vol.96 , pp. 1028-1038
    • Huang, B.S.1    Zheng, H.2    Tan, J.3    Patel, K.P.4    Leenen, F.H.5
  • 33
    • 39149132486 scopus 로고    scopus 로고
    • Aldosterone acts centrally to increase brain renin-angiotensin system activity and oxidative stress in normal rats
    • Zhang ZH, Yu Y, Kang YM, Wei SG, Felder RB. Aldosterone acts centrally to increase brain renin-angiotensin system activity and oxidative stress in normal rats. Am J Physiol 2008; 294: H1067-H1074.
    • (2008) Am J Physiol , vol.294
    • Zhang, Z.H.1    Yu, Y.2    Kang, Y.M.3    Wei, S.G.4    Felder, R.B.5
  • 34
    • 64149096607 scopus 로고    scopus 로고
    • Mechanisms in the pvn mediating local and central sodium-induced hypertension in wistar rats
    • Gabor A, Leenen FH. Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats. Am J Physiol 2009; 296: R618-R630.
    • (2009) Am J Physiol , vol.296
    • Gabor, A.1    Leenen, F.H.2
  • 35
    • 0030042760 scopus 로고    scopus 로고
    • Sympathoexcitatory and pressor responses to increased brain sodium and ouabain are mediated via brain ang ii
    • Huang BS, Leenen FH. Sympathoexcitatory and pressor responses to increased brain sodium and ouabain are mediated via brain ANG II. Am J Physiol 1996; 270: H275-H280.
    • (1996) Am J Physiol , vol.270
    • Huang, B.S.1    Leenen, F.H.2
  • 36
    • 4444325485 scopus 로고    scopus 로고
    • Pressor response to csf sodium in mice: Mediation by a ouabain-like substance and renin-angiotensin system in the brain
    • Van Huysse JW, Hou X. Pressor response to CSF sodium in mice: mediation by a ouabain-like substance and renin-angiotensin system in the brain. Brain Res 2004; 1021: 219-231.
    • (2004) Brain Res , vol.1021 , pp. 219-231
    • Van Huysse, J.W.1    Hou, X.2
  • 37
    • 34247862131 scopus 로고    scopus 로고
    • Fos-related antigen immunoreactivity after acute and chronic angiotensin ii-induced hypertension in the rabbit brain
    • Davern PJ, Head GA. Fos-related antigen immunoreactivity after acute and chronic angiotensin II-induced hypertension in the rabbit brain. Hypertension 2007; 49: 1170-1177.
    • (2007) Hypertension , vol.49 , pp. 1170-1177
    • Davern, P.J.1    Head, G.A.2
  • 38
    • 12344322276 scopus 로고    scopus 로고
    • Contribution of the subfornical organ to angiotensin ii-induced hypertension
    • Hendel MD, Collister JP. Contribution of the subfornical organ to angiotensin II-induced hypertension. Am J Physiol 2005; 288: H680-H685.
    • (2005) Am J Physiol , vol.288
    • Hendel, M.D.1    Collister, J.P.2
  • 39
    • 84873056531 scopus 로고    scopus 로고
    • Role of the nadph oxidases in the subfornical organ in angiotensin ii-induced hypertension
    • Lob HE, Schultz D, Marvar PJ, Davisson RL, Harrison DG. Role of the NADPH oxidases in the subfornical organ in angiotensin II-induced hypertension. Hypertension 2013; 61: 382-387.
    • (2013) Hypertension , vol.61 , pp. 382-387
    • Lob, H.E.1    Schultz, D.2    Marvar, P.J.3    Davisson, R.L.4    Harrison, D.G.5
  • 40
    • 66149094965 scopus 로고    scopus 로고
    • Angiotensin ii upregulates hypothalamic at1 receptor expression in rats via the mitogen-activated protein kinase pathway
    • Wei SG, Yu Y, Zhang ZH, Felder RB. Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway. Am J Physiol 2009; 296: H1425-H1433.
    • (2009) Am J Physiol , vol.296
    • Wei, S.G.1    Yu, Y.2    Zhang, Z.H.3    Felder, R.B.4
  • 41
    • 81055133082 scopus 로고    scopus 로고
    • Ace2 overexpression in the paraventricular nucleus attenuates angiotensin ii-induced hypertension
    • Sriramula S, Cardinale JP, Lazartigues E, Francis J. ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension. Cardiovasc Res 2011; 92: 401-408.
    • (2011) Cardiovasc Res , vol.92 , pp. 401-408
    • Sriramula, S.1    Cardinale, J.P.2    Lazartigues, E.3    Francis, J.4
  • 42
    • 84876694601 scopus 로고    scopus 로고
    • Central mineralocorticoid receptors and the role of ang ii and glutamate in the pvn of rats with ang ii-induced hypertension
    • Gabor A, Leenen FHH. Central mineralocorticoid receptors and the role of Ang II and glutamate in the PVN of rats with Ang II-induced hypertension. Hypertension 2013; 61: 1083-1090.
    • (2013) Hypertension , vol.61 , pp. 1083-1090
    • Gabor, A.1    Leenen, F.H.H.2
  • 43
    • 84883309048 scopus 로고    scopus 로고
    • Role of brain corticosterone and aldosterone in central angiotensin ii-induced hypertension
    • Huang BS, White RA, Ahmad M, Leenen FHH. Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension. Hypertension 2013; 62: 564-571.
    • (2013) Hypertension , vol.62 , pp. 564-571
    • Huang, B.S.1    White, R.A.2    Ahmad, M.3    Leenen, F.H.H.4
  • 44
    • 79551491358 scopus 로고    scopus 로고
    • Central interactions of aldosterone and angiotensin ii in aldosterone and angiotensin ii-induced hypertension
    • Xue B, Beltz TG, Yu Y, Guo F, Gomez-Sanchez CE, Hay M, Johnson AK. Central interactions of aldosterone and angiotensin II in aldosterone and angiotensin II-induced hypertension. Am J Physiol 2011; 300: H555-H564.
    • (2011) Am J Physiol , vol.300
    • Xue, B.1    Beltz, T.G.2    Yu, Y.3    Guo, F.4    Gomez-Sanchez, C.E.5    Hay, M.6    Johnson, A.K.7
  • 45
    • 0018750857 scopus 로고
    • Transport of steroid hormones through the rat blood-brain barrier. Primary role of albumin-bound hormone
    • Pardridge WM, Mietus LJ. Transport of steroid hormones through the rat blood-brain barrier. Primary role of albumin-bound hormone. J Clin Invest 1979; 64: 145-154.
    • (1979) J Clin Invest , vol.64 , pp. 145-154
    • Pardridge, W.M.1    Mietus, L.J.2
  • 46
  • 47
    • 84905859094 scopus 로고    scopus 로고
    • Aldosterone-salt hypertension depends on the sfo, central aldosterone synthase and mr specifically in the pvn
    • Huang BS, White RA, Leenen FHH. Aldosterone-salt Hypertension depends on the SFO, central aldosterone synthase and MR specifically in the PVN. Hypertension 2013; 62: A441.
    • (2013) Hypertension , vol.62
    • Huang, B.S.1    White, R.A.2    Leenen, F.H.H.3
  • 49
    • 78049258260 scopus 로고    scopus 로고
    • The central role of the brain aldosterone-"ouabain" pathway in salt sensitive hypertension
    • Leenen FHH. The central role of the brain aldosterone-"ouabain" pathway in salt sensitive hypertension. Biochimica Biophysica Acta 2010; 1082: 1132-1139.
    • (2010) Biochimica Biophysica Acta , vol.1082 , pp. 1132-1139
    • Leenen, F.H.H.1
  • 50
    • 84890020037 scopus 로고    scopus 로고
    • Neurogenic and sympathoexcitatory actions of nacl in hypertension
    • Stocker SD, Monahan KD, Browning KN. Neurogenic and sympathoexcitatory actions of NaCl in hypertension. Curr Hypertens Rep 2013; 15: 538-546.
    • (2013) Curr Hypertens Rep , vol.15 , pp. 538-546
    • Stocker, S.D.1    Monahan, K.D.2    Browning, K.N.3
  • 51
  • 52
    • 20344368376 scopus 로고    scopus 로고
    • Pathogenesis of hypertension in renal failure: Role of the sympathetic nervous system and renal afferents
    • Phillips JK. Pathogenesis of hypertension in renal failure: role of the sympathetic nervous system and renal afferents. Clin Exp Pharmacol Physiol 2005; 32: 415-418.
    • (2005) Clin Exp Pharmacol Physiol , vol.32 , pp. 415-418
    • Phillips, J.K.1
  • 53
    • 75449083560 scopus 로고    scopus 로고
    • Translational medicine: The antihypertensive effect of renal denervation
    • DiBona GF, Esler M. Translational medicine: the antihypertensive effect of renal denervation. Am J Physiol 2010; 298: R245-R253.
    • (2010) Am J Physiol , vol.298
    • DiBona, G.F.1    Esler, M.2
  • 54
    • 0025797392 scopus 로고
    • Electrophysiological properties of neurons in the rostral ventrolateral medulla of normotensive and spontaneously hypertensive rats
    • Chan RK, Chan YS, Wong TM. Electrophysiological properties of neurons in the rostral ventrolateral medulla of normotensive and spontaneously hypertensive rats. Brain Res 1991; 549: 118-126.
    • (1991) Brain Res , vol.549 , pp. 118-126
    • Chan, R.K.1    Chan, Y.S.2    Wong, T.M.3
  • 56
    • 0142139315 scopus 로고    scopus 로고
    • Effects of high salt intake on brain at1 receptor densities in dahl rats
    • Wang JM, Veerasingham SJ, Tan J, Leenen FH. Effects of high salt intake on brain AT1 receptor densities in Dahl rats. Am J Physiol 2003; 285: H1949-H1955.
    • (2003) Am J Physiol , vol.285
    • Wang, J.M.1    Veerasingham, S.J.2    Tan, J.3    Leenen, F.H.4
  • 57
    • 84886089553 scopus 로고    scopus 로고
    • Brain angiotensinconverting enzyme type 2 shedding contributes to the development of neurogenic hypertension
    • Xia H, Sriramula S, Chhabra KH, Lazartigues E. Brain angiotensinconverting enzyme type 2 shedding contributes to the development of neurogenic hypertension. Circ Res 2013; 113: 1087-1096.
    • (2013) Circ Res , vol.113 , pp. 1087-1096
    • Xia, H.1    Sriramula, S.2    Chhabra, K.H.3    Lazartigues, E.4
  • 59
    • 33748169328 scopus 로고    scopus 로고
    • Oxidative stress mediates the stimulation of sympathetic nerve activity in the phenol renal injury model of hypertension
    • Ye S, Zhong H, Yanamadala S, Campese VM. Oxidative stress mediates the stimulation of sympathetic nerve activity in the phenol renal injury model of hypertension. Hypertension 2006; 48: 309-315.
    • (2006) Hypertension , vol.48 , pp. 309-315
    • Ye, S.1    Zhong, H.2    Yanamadala, S.3    Campese, V.M.4
  • 60
    • 84880881146 scopus 로고    scopus 로고
    • The role of cns in salt-sensitive hypertension
    • Fujita M, Fujita T. The role of CNS in salt-sensitive hypertension. Curr Hypertens Rep 2013; 15: 390-394.
    • (2013) Curr Hypertens Rep , vol.15 , pp. 390-394
    • Fujita, M.1    Fujita, T.2
  • 61
    • 84859519649 scopus 로고    scopus 로고
    • Central infusion of aliskiren prevents sympathetic hyperactivity and hypertension in dahl salt-sensitive rats on high salt intake
    • Huang BS, White RA, Bi L, Leenen FH. Central infusion of aliskiren prevents sympathetic hyperactivity and hypertension in Dahl salt-sensitive rats on high salt intake. Am J Physiol 2012; 302: R825-R832.
    • (2012) Am J Physiol , vol.302
    • Huang, B.S.1    White, R.A.2    Bi, L.3    Leenen, F.H.4
  • 62
    • 84858440774 scopus 로고    scopus 로고
    • Cardiovascular effects of angiotensin ii and glutamate in the pvn of dahl salt-sensitive rats
    • Gabor A, Leenen FH. Cardiovascular effects of angiotensin II and glutamate in the PVN of Dahl salt-sensitive rats. Brain Res 2012; 1447: 28-37.
    • (2012) Brain Res , vol.1447 , pp. 28-37
    • Gabor, A.1    Leenen, F.H.2
  • 63
    • 0037341456 scopus 로고    scopus 로고
    • Ventrolateral medulla at1 receptors support arterial pressure in dahl salt-sensitive rats
    • Ito S, Hiratsuka M, Komatsu K, Tsukamoto K, Kanmatsuse K, Sved AF. Ventrolateral medulla AT1 receptors support arterial pressure in Dahl salt-sensitive rats. Hypertension 2003; 41: 744-750.
    • (2003) Hypertension , vol.41 , pp. 744-750
    • Ito, S.1    Hiratsuka, M.2    Komatsu, K.3    Tsukamoto, K.4    Kanmatsuse, K.5    Sved, A.F.6
  • 65
    • 65749115258 scopus 로고    scopus 로고
    • Role of central nervous system aldosterone synthase and mineralocorticoid receptors in saltinduced hypertension in dahl salt-sensitive rats
    • Huang BS, White RA, Jeng AY, Leenen FH. Role of central nervous system aldosterone synthase and mineralocorticoid receptors in saltinduced hypertension in Dahl salt-sensitive rats. Am J Physiol 2009; 296: R994-R1000.
    • (2009) Am J Physiol , vol.296
    • Huang, B.S.1    White, R.A.2    Jeng, A.Y.3    Leenen, F.H.4
  • 66
    • 0036315049 scopus 로고    scopus 로고
    • Brain sodium channels mediate increases in brain "ouabain" and blood pressure in dahl s rats
    • Wang H, Leenen FH. Brain sodium channels mediate increases in brain "ouabain" and blood pressure in Dahl S rats. Hypertension 2002; 40: 96-100.
    • (2002) Hypertension , vol.40 , pp. 96-100
    • Wang, H.1    Leenen, F.H.2
  • 67
    • 4143092554 scopus 로고    scopus 로고
    • Increases in csf [na+] precede the increases in blood pressure in dahl s rats and shr on a high-salt diet
    • Huang BS, Van Vliet BN, Leenen FH. Increases in CSF [Na+] precede the increases in blood pressure in Dahl S rats and SHR on a high-salt diet. Am J Physiol Heart Circ Physiol 2004; 287: H1160-H1166.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Huang, B.S.1    Van Vliet, B.N.2    Leenen, F.H.3
  • 68
    • 0024594926 scopus 로고
    • Sequential changes of cerebrospinal fluid sodium during the development of hypertension in dahl rats
    • Nakamura K, Cowley AW Jr. Sequential changes of cerebrospinal fluid sodium during the development of hypertension in Dahl rats. Hypertension 1989; 13: 243-249.
    • (1989) Hypertension , vol.13 , pp. 243-249
    • Nakamura, K.1    Cowley Jr., A.W.2
  • 70
    • 12344256742 scopus 로고    scopus 로고
    • Effect of 3beta-hydroxysteroid dehydrogenase inhibition by trilostane on blood pressure in the dahl salt-sensitive rat
    • Gomez-Sanchez EP, Samuel J, Vergara G, Ahmad N. Effect of 3beta-hydroxysteroid dehydrogenase inhibition by trilostane on blood pressure in the Dahl salt-sensitive rat. Am J Physiol 2005; 288: R389-R393.
    • (2005) Am J Physiol , vol.288
    • Gomez-Sanchez, E.P.1    Samuel, J.2    Vergara, G.3    Ahmad, N.4
  • 71
    • 33750807730 scopus 로고    scopus 로고
    • Blockade of brain "ouabain" prevents sympathoexcitatory and pressor responses to high sodium in shr
    • Huang BS, Leenen FH. Blockade of brain "ouabain" prevents sympathoexcitatory and pressor responses to high sodium in SHR. Am J Physiol 1996; 271: H103-H108.
    • (1996) Am J Physiol , vol.271
    • Huang, B.S.1    Leenen, F.H.2
  • 72
    • 0029852894 scopus 로고    scopus 로고
    • Brain "ouabain" and angiotensin ii in salt sensitive hypertension in spontaneously hypertensive rats
    • Huang BS, Leenen FH. Brain "ouabain" and angiotensin II in salt sensitive hypertension in spontaneously hypertensive rats. Hypertension 1996; 28: 1005-1012.
    • (1996) Hypertension , vol.28 , pp. 1005-1012
    • Huang, B.S.1    Leenen, F.H.2
  • 73
    • 65449178018 scopus 로고    scopus 로고
    • Acquisition of brain na sensitivity contributes to salt-induced sympathoexcitation and cardiac dysfunction in mice with pressure overload
    • Ito K, Hirooka Y, Sunagawa K. Acquisition of brain Na sensitivity contributes to salt-induced sympathoexcitation and cardiac dysfunction in mice with pressure overload. Circ Res 2009; 104: 1004-1011.
    • (2009) Circ Res , vol.104 , pp. 1004-1011
    • Ito, K.1    Hirooka, Y.2    Sunagawa, K.3
  • 74
    • 77956876683 scopus 로고    scopus 로고
    • Sympathetic neural activity in hypertension and related diseases
    • Grassi G. Sympathetic neural activity in hypertension and related diseases. Am J Hypertens 2010; 23: 1052-1060.
    • (2010) Am J Hypertens , vol.23 , pp. 1052-1060
    • Grassi, G.1
  • 75
    • 0022591615 scopus 로고
    • Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure
    • Leimbach WN Jr, Wallin BG, Victor RG, Aylward PE, Sundlöf G, Mark AL. Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure. Circulation 1986; 73: 913-999.
    • (1986) Circulation , vol.73 , pp. 913-999
    • Leimbach Jr., W.N.1    Wallin, B.G.2    Victor, R.G.3    Aylward, P.E.4    Sundlöf, G.5    Mark, A.L.6
  • 76
    • 67650531390 scopus 로고    scopus 로고
    • Sympathetic nervous system activation in human heart failure: Clinical implications of an updated model
    • Floras JS. Sympathetic nervous system activation in human heart failure: clinical implications of an updated model. J Am Coll Cardiol 2009; 54: 375-385.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 375-385
    • Floras, J.S.1
  • 77
    • 0033091735 scopus 로고    scopus 로고
    • Cardiovascular consequences of sympathetic hyperactivity
    • Leenen FHH. Cardiovascular consequences of sympathetic hyperactivity. Can J Cardiol 1999; 15: 2A-7A.
    • (1999) Can J Cardiol , vol.15
    • Leenen, F.H.H.1
  • 78
    • 55949135607 scopus 로고    scopus 로고
    • Prevention of salt induced hypertension and fibrosis by at1-receptor blockers in dahl s rats
    • Liang B, Leenen FHH. Prevention of salt induced hypertension and fibrosis by AT1-receptor blockers in Dahl S rats. J Cardiovasc Pharmacol 2008; 51: 457-466.
    • (2008) J Cardiovasc Pharmacol , vol.51 , pp. 457-466
    • Liang, B.1    Leenen, F.H.H.2
  • 79
    • 0035101357 scopus 로고    scopus 로고
    • Prevention of hypertension by irbesartan in dahl s rats relates to central at1 receptor blockade
    • Leenen FHH, Yuan B. Prevention of hypertension by irbesartan in Dahl S rats relates to central AT1 receptor blockade. Hypertension 2001; 37: 981-984.
    • (2001) Hypertension , vol.37 , pp. 981-984
    • Leenen, F.H.H.1    Yuan, B.2
  • 80
    • 33646084866 scopus 로고    scopus 로고
    • Effect of angiotensin ii receptor blockade on autonomic nervous system function in patients with essential hypertension
    • Krum H, Lambert E, Windebank E, Campbell DJ, Esler M. Effect of angiotensin II receptor blockade on autonomic nervous system function in patients with essential hypertension. Am J Physiol 2006; 290: H1706-H1712.
    • (2006) Am J Physiol , vol.290
    • Krum, H.1    Lambert, E.2    Windebank, E.3    Campbell, D.J.4    Esler, M.5
  • 81
    • 84864276593 scopus 로고    scopus 로고
    • Spironolactone prevents chlorthalidone induced sympathetic activation and insulin resistance in hypertensive patients
    • Raheja P, Price A, Wang Z, Arbique D, Adams-Huet B, Auchus RJ, Vongpatanasin W. Spironolactone prevents chlorthalidone induced sympathetic activation and insulin resistance in hypertensive patients. Hypertension 2012; 60: 319-325.
    • (2012) Hypertension , vol.60 , pp. 319-325
    • Raheja, P.1    Price, A.2    Wang, Z.3    Arbique, D.4    Adams-Huet, B.5    Auchus, R.J.6    Vongpatanasin, W.7
  • 82
    • 84874749758 scopus 로고    scopus 로고
    • Do high doses of at1-receptor blockers attenuate central sympathetic outflow in humans with chronic heart failure?
    • Ruzicka M, Floras J, McReynolds AG, Coletta E, Haddad H, Davies R, Leenen FHH. Do high doses of AT1-receptor blockers attenuate central sympathetic outflow in humans with chronic heart failure? Clin Sci 2013; 124: 589-595.
    • (2013) Clin Sci , vol.124 , pp. 589-595
    • Ruzicka, M.1    Floras, J.2    McReynolds, A.G.3    Coletta, E.4    Haddad, H.5    Davies, R.6    Leenen, F.H.H.7
  • 85
    • 0035203390 scopus 로고    scopus 로고
    • Central mineralocorticoid receptor blockade improves volume regulation and reduces sympathetic drive in heart failure
    • Francis J, Weiss RM, Wei SG, Johnson AK, Beltz TG, Zimmerman K, Felder RB. Central mineralocorticoid receptor blockade improves volume regulation and reduces sympathetic drive in heart failure. Am J Physiol 2001; 281: H2241-H2251.
    • (2001) Am J Physiol , vol.281
    • Francis, J.1    Weiss, R.M.2    Wei, S.G.3    Johnson, A.K.4    Beltz, T.G.5    Zimmerman, K.6    Felder, R.B.7
  • 86
    • 65249137181 scopus 로고    scopus 로고
    • Differential effects of chlorthalidone versus spironolactone on muscle sympathetic nerve activity in hypertensive patients
    • Menon DV, Arbique D, Wang Z, Adams-Huet B, Auchus RJ, Vongpatanasin W. Differential effects of chlorthalidone versus spironolactone on muscle sympathetic nerve activity in hypertensive patients. J Clin Endocrinol Metab 2009; 94: 1361-1366.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1361-1366
    • Menon, D.V.1    Arbique, D.2    Wang, Z.3    Adams-Huet, B.4    Auchus, R.J.5    Vongpatanasin, W.6
  • 87
    • 77951451927 scopus 로고    scopus 로고
    • Impact of aldosterone receptor blockade compared with thiazide therapy on sympathetic nervous system function in geriatric hypertension
    • Wray DW, Supiano MA. Impact of aldosterone receptor blockade compared with thiazide therapy on sympathetic nervous system function in geriatric hypertension. Hypertension 2010; 55: 1217-1223.
    • (2010) Hypertension , vol.55 , pp. 1217-1223
    • Wray, D.W.1    Supiano, M.A.2
  • 88
    • 84867508685 scopus 로고    scopus 로고
    • Central neuromodulatory pathways regulating sympathetic activity in hypertension
    • Gabor A, Leenen FHH. Central neuromodulatory pathways regulating sympathetic activity in hypertension. J Applied Physiol 2012; 113: 1294-1303.
    • (2012) J Applied Physiol , vol.113 , pp. 1294-1303
    • Gabor, A.1    Leenen, F.H.H.2


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