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Volumn 59, Issue 2, 2011, Pages 104-108

An ouabain-like factor is secreted from immortalized hypothalamic cells in an aldosterone-dependent manner

Author keywords

Aldosterone; ELISA; Endogenous digitalis; Eplerenone; Immortalized hypothalamic cell; Ouabain

Indexed keywords

ALDOSTERONE; DIGITALIS LIKE FACTOR; EPLERENONE; MINERALOCORTICOID RECEPTOR; OUABAIN; PROTEIN ANTIBODY;

EID: 79960350166     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.04.019     Document Type: Article
Times cited : (18)

References (44)
  • 2
    • 70349655257 scopus 로고    scopus 로고
    • Sodium transport in the choroid plexus and salt-sensitive hypertension
    • M.S. Amin, E. Reza, H. Wang, and F.H. Leenen Sodium transport in the choroid plexus and salt-sensitive hypertension Hypertension 54 2009 860 867
    • (2009) Hypertension , vol.54 , pp. 860-867
    • Amin, M.S.1    Reza, E.2    Wang, H.3    Leenen, F.H.4
  • 4
    • 46249110505 scopus 로고    scopus 로고
    • Endogenous digitalis: Pathophysiologic roles and therapeutic applications
    • DOI 10.1038/ncpneph0848, PII NCPNEPH0848
    • A.Y. Bagrov, and J.I. Shapiro Endogenous digitalis: pathophysiologic roles and therapeutic applications Nat. Clin. Pract. Nephrol. 4 2008 378 392 (Pubitemid 351913708)
    • (2008) Nature Clinical Practice Nephrology , vol.4 , Issue.7 , pp. 378-392
    • Bagrov, A.Y.1    Shapiro, J.I.2
  • 5
    • 0017184389 scopus 로고
    • Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • M.M. Bradford Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 6
    • 0030668103 scopus 로고    scopus 로고
    • Effect of high salt intake on plasma and tissue concentration of endogenous ouabain-like substance in the rat
    • DOI 10.1016/S0024-3205(97)00953-3, PII S0024320597009533
    • A.N. Butt, Y.K. Semra, C.S. Ho, and R. Swaminathan Effect of high salt intake on plasma and tissue concentration of endogenous ouabain-like substance in the rat Life. Sci. 61 1997 2367 2373 (Pubitemid 27497067)
    • (1997) Life Sciences , vol.61 , Issue.24 , pp. 2367-2373
    • Butt, A.N.1    Semra, Y.K.2    Ho, C.S.3    Swaminathan, R.4
  • 7
    • 0001456109 scopus 로고
    • Studies on the efferent mechanism of the sodium diuresis, which follows the administration of intravenous saline in the dog
    • H.E. de Wardner, J.H. Mills, W.F. Clanpham, and C.J. Hayer Studies on the efferent mechanism of the sodium diuresis, which follows the administration of intravenous saline in the dog Clin. Sci. 21 1961 249 258
    • (1961) Clin. Sci. , vol.21 , pp. 249-258
    • De Wardner, H.E.1    Mills, J.H.2    Clanpham, W.F.3    Hayer, C.J.4
  • 8
    • 0033812873 scopus 로고    scopus 로고
    • Mammalian bufadienolide is synthesized from cholesterol in the adrenal cortex by a pathway that Is independent of cholesterol side-chain cleavage
    • R.I. Dmitrieva, A.Y. Bagrov, E. Lalli, P. Sassone-Corsi, D.M. Stocco, and P.A. Doris Mammalian bufadienolide is synthesized from cholesterol in the adrenal cortex by a pathway that Is independent of cholesterol side-chain cleavage Hypertension 36 2000 442 448
    • (2000) Hypertension , vol.36 , pp. 442-448
    • Dmitrieva, R.I.1    Bagrov, A.Y.2    Lalli, E.3    Sassone-Corsi, P.4    Stocco, D.M.5    Doris, P.A.6
  • 9
    • 0030023091 scopus 로고    scopus 로고
    • Ouabain production by cultured adrenal cells
    • DOI 10.1210/en.137.2.533
    • P.A. Doris, A. Hayward-Lester, D. Bourne, and D.M. Stocco Ouabain production by cultured adrenal cells Endocrinology 137 1996 533 539 (Pubitemid 26043747)
    • (1996) Endocrinology , vol.137 , Issue.2 , pp. 533-539
    • Doris, P.A.1    Hayward-Lester, A.2    Bourne, D.3    Stocco, D.M.4
  • 13
    • 0026722218 scopus 로고
    • Brain ouabain-like activity and the sympathoexcitatory and pressor effects of central sodium in rats
    • B.S. Huang, E. Harmsen, H. Yu, and F.H. Leenen Brain ouabain-like activity and the sympathoexcitatory and pressor effects of central sodium in rats Circ. Res. 71 1992 1059 1066
    • (1992) Circ. Res. , vol.71 , pp. 1059-1066
    • Huang, B.S.1    Harmsen, E.2    Yu, H.3    Leenen, F.H.4
  • 14
    • 0028353962 scopus 로고
    • Brain "ouabain" mediates the sympathoexcitatory and hypertensive effects of high sodium intake in Dahl salt-sensitive rats
    • B.S. Huang, and F.H. Leenen Brain "ouabain" mediates the sympathoexcitatory and hypertensive effects of high sodium intake in Dahl salt-sensitive rats Circ. Res. 74 1994 586 595
    • (1994) Circ. Res. , vol.74 , pp. 586-595
    • Huang, B.S.1    Leenen, F.H.2
  • 15
    • 33750807730 scopus 로고    scopus 로고
    • Blockade of brain "ouabain" prevents sympathoexcitatory and pressor responses to high sodium in SHR
    • B.S. Huang, and F.H. Leenen Blockade of brain "ouabain" prevents sympathoexcitatory and pressor responses to high sodium in SHR Am. J. Physiol. 271 1996 H103 H108
    • (1996) Am. J. Physiol. , vol.271
    • Huang, B.S.1    Leenen, F.H.2
  • 16
    • 0030042760 scopus 로고    scopus 로고
    • Sympathoexcitatory and pressor responses to increased brain sodium and ouabain are mediated via brain ANG II
    • B.S. Huang, and F.H. Leenen Sympathoexcitatory and pressor responses to increased brain sodium and ouabain are mediated via brain ANG II Am. J. Physiol. 270 1996 H275 H280
    • (1996) Am. J. Physiol. , vol.270
    • Huang, B.S.1    Leenen, F.H.2
  • 17
    • 0031006894 scopus 로고    scopus 로고
    • Sympathoexcitatory effect of hypothalamic/hypophysary inhibitory factor in rats
    • B.S. Huang, J.M. Sancho, R. Garcia-Robles, and F.H. Leenen Sympathoexcitatory effect of hypothalamic/hypophysary inhibitory factor in rats Hypertension 29 1997 1291 1295 (Pubitemid 27233179)
    • (1997) Hypertension , vol.29 , Issue.6 , pp. 1291-1295
    • Huang, B.S.1    Sancho, J.M.2    Garcia-Robles, R.3    Leenen, F.H.H.4
  • 18
    • 0032437664 scopus 로고    scopus 로고
    • Both brain angiotensin II and 'ouabain' contribute to sympathoexcitation and hypertension in Dahl S rats on high salt intake
    • B.S. Huang, and F.H. Leenen Both brain angiotensin II and "ouabain" contribute to sympathoexcitation and hypertension in Dahl S rats on high salt intake Hypertension 32 1998 1028 1033 (Pubitemid 29001431)
    • (1998) Hypertension , vol.32 , Issue.6 , pp. 1028-1033
    • Huang, B.S.1    Leenen, F.H.H.2
  • 19
    • 0032811793 scopus 로고    scopus 로고
    • Brain renin-angiotensin system and ouabain-induced sympathetic hyperactivity and hypertension in wistar rats
    • B.S. Huang, and F.H. Leenen Brain renin-angiotensin system and ouabain-induced sympathetic hyperactivity and hypertension in Wistar rats Hypertension 34 1999 107 112 (Pubitemid 29325727)
    • (1999) Hypertension , vol.34 , Issue.1 , pp. 107-112
    • Huang, B.S.1    Leenen, F.H.H.2
  • 20
    • 12344311875 scopus 로고    scopus 로고
    • Chronic central infusion of aldosterone leads to sympathetic hyperreactivity and hypertension in Dahl S but not Dahl R rats
    • B.S. Huang, H. Wang, and F.H. Leenen Chronic central infusion of aldosterone leads to sympathetic hyperreactivity and hypertension in Dahl S but not Dahl R rats Am. J. Physiol. Heart. Circ. Physiol. 288 2005 H517 H524
    • (2005) Am. J. Physiol. Heart. Circ. Physiol. , vol.288
    • Huang, B.S.1    Wang, H.2    Leenen, F.H.3
  • 21
    • 65749115258 scopus 로고    scopus 로고
    • Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats
    • B.S. Huang, R.A. White, A.Y. Jeng, and F.H. Leenen Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats Am. J. Physiol. Regul. Integr. Comp. Physiol. 296 2009 R994 R1000
    • (2009) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.296
    • Huang, B.S.1    White, R.A.2    Jeng, A.Y.3    Leenen, F.H.4
  • 22
    • 77955462845 scopus 로고    scopus 로고
    • Central neuronal activation and pressor responses induced by circulating ANG II: Role of the brain aldosterone-"ouabain" pathway
    • B.S. Huang, S. Ahmadi, M. Ahmad, R.A. White, and F.H. Leenen Central neuronal activation and pressor responses induced by circulating ANG II: role of the brain aldosterone-"ouabain" pathway Am. J. Physiol. Heart Circ. Physiol. 299 2010 H422 H430
    • (2010) Am. J. Physiol. Heart Circ. Physiol. , vol.299
    • Huang, B.S.1    Ahmadi, S.2    Ahmad, M.3    White, R.A.4    Leenen, F.H.5
  • 23
    • 67650447356 scopus 로고    scopus 로고
    • Regulatory mechanisms underlying corticotropin-releasing factor gene expression in the hypothalamus
    • K. Kageyama, and T. Suda Regulatory mechanisms underlying corticotropin-releasing factor gene expression in the hypothalamus Endocr. J. 56 2009 335 344
    • (2009) Endocr. J. , vol.56 , pp. 335-344
    • Kageyama, K.1    Suda, T.2
  • 25
    • 0029072889 scopus 로고
    • Production of ouabain-like factors of hypothalamo-pituitary origin, determined by a sensitive ELISA for ouabain, is increased in DOCA-salt hypertensive rats
    • Y. Komiyama, T. Mori, K. Okuda, T. Murakami, M. Masuda, and H. Takahashi Production of ouabain-like factors of hypothalamo-pituitary origin, determined by a sensitive ELISA for ouabain, is increased in DOCA-salt hypertensive rats Pathophysiology 2 1995 35 40
    • (1995) Pathophysiology , vol.2 , pp. 35-40
    • Komiyama, Y.1    Mori, T.2    Okuda, K.3    Murakami, T.4    Masuda, M.5    Takahashi, H.6
  • 26
    • 0029954729 scopus 로고    scopus 로고
    • Effects of intracerebroventricular administration of 6-hydroxydopamine on ouabain-like immunoreactivity in plasma and the hypothalamo-pituitary axis in rats
    • Y. Komiyama, T. Mori, K. Okuda, M. Munakata, T. Murakami, M. Masuda, A. Goto, K. Yamada, and H. Takahashi Effects of intracerebroventricular administration of 6-hydroxydopamine on ouabain-like immunoreactivity in plasma and the hypothalamo-pituitary axis in rats J. Hypertens. 14 1996 447 452 (Pubitemid 26161093)
    • (1996) Journal of Hypertension , vol.14 , Issue.4 , pp. 447-452
    • Komiyama, Y.1    Mori, T.2    Okuda, K.3    Munakata, M.4    Murakami, T.5    Masuda, M.6    Goto, A.7    Yamada, K.8    Takahashi, H.9
  • 27
    • 0032790046 scopus 로고    scopus 로고
    • Increases in plasma ouabainlike immunoreactivity during surgical extirpation of pheochromocytoma
    • Y. Komiyama, N. Nishimura, M. Munakata, K. Okuda, N. Nishino, C. Kosaka, M. Masuda, T. Mori, T. Matsuda, and H. Takahashi Increases in plasma ouabainlike immunoreactivity during surgical extirpation of pheochromocytoma Hypertens. Res. 22 1999 135 139 (Pubitemid 29371687)
    • (1999) Hypertension Research - Clinical and Experimental , vol.22 , Issue.2 , pp. 135-139
    • Komiyama, Y.1
  • 29
    • 10644255834 scopus 로고    scopus 로고
    • A novel endogenous digitalis, telocinobufagin, exhibits elevated plasma levels in patients with terminal renal failure
    • DOI 10.1016/j.clinbiochem.2004.08.005, PII S0009912004002371
    • Y. Komiyama, X.H. Dong, N. Nishimura, H. Masaki, M. Yoshika, M. Masuda, and H. Takahashi A novel endogenous digitalis, telocinobufagin, exhibits elevated plasma levels in patients with terminal renal failure Clin. Biochem. 38 2005 36 45 (Pubitemid 39647654)
    • (2005) Clinical Biochemistry , vol.38 , Issue.1 , pp. 36-45
    • Komiyama, Y.1    Dong, X.H.2    Nishimura, N.3    Masaki, H.4    Yoshika, M.5    Masuda, M.6    Takahashi, H.7
  • 30
    • 0032078274 scopus 로고    scopus 로고
    • Biosynthesis of digitalis-like compounds in rat adrenal cells: Hydroxycholesterol as possible precursor
    • DOI 10.1016/S0024-3205(98)00186-6, PII S0024320598001866
    • D. Lichtstein, M. Steinitz, I. Gati, S. Samuelov, J. Deutsch, and J. Orly Biosynthesis of digitalis-like compounds in rat adrenal cells: hydroxycholesterol as possible precursor Life Sci. 62 1998 2109 2126 (Pubitemid 28239727)
    • (1998) Life Sciences , vol.62 , Issue.23 , pp. 2109-2126
    • Lichtstein, D.1    Steinitz, M.2    Gati, I.3    Samuelov, S.4    Deutsch, J.5    Orly, J.6
  • 31
  • 32
    • 67651235884 scopus 로고    scopus 로고
    • Hypothalamic cell lines to investigate neuroendocrine control mechanisms
    • C.M. Mayer, L.J. Fick, S. Gingerich, and D.D. Belsham Hypothalamic cell lines to investigate neuroendocrine control mechanisms Front. Neuroendocrinol 30 2009 405 423
    • (2009) Front. Neuroendocrinol , vol.30 , pp. 405-423
    • Mayer, C.M.1    Fick, L.J.2    Gingerich, S.3    Belsham, D.D.4
  • 33
    • 24644466684 scopus 로고    scopus 로고
    • Endogenous ouabain: Upregulation of steroidogenic genes in hypertensive hypothalamus but not adrenal
    • DOI 10.1161/CIRCULATIONAHA.105.554071
    • J.R. Murrell, J.D. Randall, J. Rosoff, J.L. Zhao, R.V. Jensen, S.R. Gullans, and G.T. Haupert Jr. Endogenous ouabain: upregulation of steroidogenic genes in hypertensive hypothalamus but not adrenal Circulation 112 2005 1301 1308 (Pubitemid 41266725)
    • (2005) Circulation , vol.112 , Issue.9 , pp. 1301-1308
    • Murrell, J.R.1    Randall, J.D.2    Rosoff, J.3    Zhao, J.-L.4    Jensen, R.V.5    Gullans, S.R.6    Haupert, G.T.7
  • 34
    • 0031016234 scopus 로고    scopus 로고
    • Bovine adrenocortical cells in culture synthesize an ouabain-like compound
    • DOI 10.1016/S0303-7207(96)03964-0, PII S0303720796039640
    • A. Perrin, B. Brasmes, E.M. Chambaz, and G. Defaye Bovine adrenocortical cells in culture synthesize an ouabain-like compound Mol. Cell. Endocrinol. 126 1997 7 15 (Pubitemid 27055543)
    • (1997) Molecular and Cellular Endocrinology , vol.126 , Issue.1 , pp. 7-15
    • Perrin, A.1    Brasmes, B.2    Chambaz, E.M.3    Defaye, G.4
  • 35
    • 1542358869 scopus 로고    scopus 로고
    • De Novo Biosynthesis and Radiolabeling of Mammalian Digitalis-Like Factors
    • DOI 10.1373/clinchem.2003.022715
    • H.M. Qazzaz, Z. Cao, D.D. Bolanowski, B.J. Clark, and R. Valdes Jr. De novo biosynthesis and radiolabeling of mammalian digitalis-like factors Clin. Chem. 50 2004 612 620 (Pubitemid 38297313)
    • (2004) Clinical Chemistry , vol.50 , Issue.3 , pp. 612-620
    • Qazzaz, H.M.A.M.1    Cao, Z.2    Bolanowski, D.D.3    Clark, B.J.4    Valdes Jr., R.5
  • 36
    • 0031873692 scopus 로고    scopus 로고
    • A non-ouabain NA/K atpase inhibitor isolated from bovine hypothalamus. Its relation to hypothalamic ouabain
    • J.M. Sancho A non-ouabain Na/K ATPase inhibitor isolated from bovine hypothalamus. Its relation to hypothalamic ouabain Clin. Exp. Hypertens. 20 1998 535 542 (Pubitemid 28319525)
    • (1998) Clinical and Experimental Hypertension , vol.20 , Issue.5-6 , pp. 535-542
    • Sancho, J.M.1
  • 37
    • 34447325644 scopus 로고    scopus 로고
    • Endogenous and exogenous cardiac glycosides and their mechanisms of action
    • DOI 10.2165/00129784-200707030-00004
    • W. Schoner, and G. Scheiner-Bobis Endogenous and exogenous cardiac glycosides and their mechanisms of action Am. J. Cardiovasc. Drugs 7 2007 173 189 (Pubitemid 47049626)
    • (2007) American Journal of Cardiovascular Drugs , vol.7 , Issue.3 , pp. 173-189
    • Schoner, W.1    Scheiner-Bobis, G.2
  • 40
    • 0026729405 scopus 로고
    • Distribution of the endogenous digitalis-like substance (EDLS)-containing neurons labeled by digoxin antibody in hypothalamus and three circumventricular organs of dog and macaque
    • H. Yamada, N. Ihara, H. Takahashi, M. Yoshimura, and Y. Sano Distribution of the endogenous digitalis-like substance (EDLS)-containing neurons labeled by digoxin antibody in hypothalamus and three circumventricular organs of dog and macaque Brain Res. 584 1992 237 243
    • (1992) Brain Res. , vol.584 , pp. 237-243
    • Yamada, H.1    Ihara, N.2    Takahashi, H.3    Yoshimura, M.4    Sano, Y.5
  • 41
    • 33847682886 scopus 로고    scopus 로고
    • Novel digitalis-like factor, marinobufotoxin, isolated from cultured Y-1 cells, and its hypertensive effect in rats
    • DOI 10.1161/01.HYP.0000250433.64202.78, PII 0000426820070100000037
    • M. Yoshika, Y. Komiyama, M. Konishi, T. Akizawa, T. Kobayashi, M. Date, S. Kobatake, M. Masuda, H. Masaki, and H. Takahashi Novel digitalis-like factor, marinobufotoxin, isolated from cultured Y-1 cells, and its hypertensive effect in rats Hypertension 49 2007 209 214 (Pubitemid 46360362)
    • (2007) Hypertension , vol.49 , Issue.1 , pp. 209-214
    • Yoshika, M.1    Komiyama, Y.2    Konishi, M.3    Akizawa, T.4    Kobayashi, T.5    Date, M.6    Kobatake, S.7    Masuda, M.8    Masaki, H.9    Takahashi, H.10
  • 42
    • 79955386596 scopus 로고    scopus 로고
    • Isolation of marinobufotoxin from the supernatant of cultured PC12 cells
    • M. Yoshika, Y. Komiyama, and H. Takahashi Isolation of marinobufotoxin from the supernatant of cultured PC12 cells Clin. Exp. Pharmacol Physiol. 38 2011 334 337
    • (2011) Clin. Exp. Pharmacol Physiol. , vol.38 , pp. 334-337
    • Yoshika, M.1    Komiyama, Y.2    Takahashi, H.3
  • 43
    • 0242574272 scopus 로고    scopus 로고
    • Transgenesis and the study of expression, cellular targeting and function of oxytocin, vasopressin and their receptors
    • DOI 10.1159/000073702
    • W.S. Young 3rd, and H. Gainer Transgenesis and the study of expression, cellular targeting and function of oxytocin, vasopressin and their receptors Neuroendocrinology 78 2003 185 203 (Pubitemid 37409833)
    • (2003) Neuroendocrinology , vol.78 , Issue.4 , pp. 185-203
    • Young III, W.S.1    Gainer, H.2
  • 44
    • 33746022627 scopus 로고    scopus 로고
    • 11β-hydroxysteroid dehydrogenase type 2 activity in hypothalamic paraventricular nucleus modulates sympathetic excitation
    • DOI 10.1161/01.HYP.0000224296.96235.dd, PII 0000426820060700000024
    • Z.H. Zhang, Y.M. Kang, Y. Yu, S.G. Wei, T.J. Schmidt, A.K. Johnson, and R.B. Felder 11beta-hydroxysteroid dehydrogenase type 2 activity in hypothalamic paraventricular nucleus modulates sympathetic excitation Hypertension 48 2006 127 133 (Pubitemid 44297534)
    • (2006) Hypertension , vol.48 , Issue.1 , pp. 127-133
    • Zhang, Z.-H.1    Kang, Y.-M.2    Yu, Y.3    Wei, S.-G.4    Schmidt, T.J.5    Johnson, A.K.6    Felder, R.B.7


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