Translational medicine: The antihypertensive effect of renal denervation

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 298, Issue 2, 2010, Pages

  DiBona, Gerald F ^a   Esler, Murray ^b  

^a UNIVERSITY OF IOWA   (United States)

^b BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

RENIN;

ARTERIAL PRESSURE; HUMAN; HYPERTENSION; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY NERVE; NONHUMAN; PRIORITY JOURNAL; RENIN RELEASE; REVIEW; SODIUM URINE LEVEL; SYMPATHETIC NERVE;

ANIMALS; GLOMERULAR FILTRATION RATE; HUMANS; HYPERTENSION; KIDNEY; RENAL CIRCULATION; RENIN; SYMPATHECTOMY; SYMPATHETIC NERVOUS SYSTEM; TRANSLATIONAL RESEARCH;

EID: 75449083560     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00647.2009     Document Type: Review

References (57)

1. Barajas L. The innervation of the juxtaglomerular apparatus. An electron microscopic study of the innervation of the glomerular arterioles. Lab Invest 13: 916-929, 1964.
2. Barajas L, Liu L, Powers K. Anatomy of the renal innervation: intrarenal aspects and ganglia of origin. Can J Physiol Pharmacol 70: 735-749, 1992.
3. Bernard C. Leçons sur les Propriétés et les Altérations Pathologiques des Liquides de L'Organisme. Paris: Bailliére et Fils, 1859, vol. 2, p. 170-171.
4. Biaggioni I. Should we target the sympathetic nervous system in the treatment of obesity-associated hypertension? Hypertension 51: 168-171, 2008.
5. Campese VM, Kogosov E. Renal afferent denervation prevents hypertension in rats with chronic renal failure. Hypertension 25: 878-882, 1995.
6. Chandola T, Brunner E, Marmot M. Chronic stress at work and the metabolic syndrome. Br Med J 332: 521-524, 2006.
7. Converse RL, Jacobsen TN, Toto RD, Jost CMT, Cosentino F, Fouad-Tarazi F, Victor RG. Sympathetic overactivity in patients with chronic renal failure. N Engl J Med 327: 1912-1918, 1992.
8. Cowley AW. Long term control of arterial blood pressure. Physiol Rev 72: 231-300, 1992.
9. Davies SJ, Ghahramani P, Jackson PR, Noble TW, Hardy PG, Hippislet-Cox J, Yeo WW, Ramsay LE. Association of panic disorder and panic attacks with hypertension. Am J Med 107: 310-316, 1999.
10. De Muylder CG. The Neurility of the Kidney. Springfield, IL: Thomas, 1952.
11. DiBona GF. The functions of the renal nerves. Rev Physiol Biochem Pharmacol 94: 75-181, 1982.
12. DiBona GF, Kopp UC. Neural control of renal function. Physiol Rev 77: 76-197, 1997.
13. DiBona GF. Renal innervation and denervation: lessons from renal transplantation reconsidered. Artif Organs 11: 457-462, 1987.
14. DiBona GF. Physiology in perspective: the wisdom of the body. Neural control of the kidney. Am J Physiol Regul Integr Comp Physiol 289: R633-R641, 2005.
15. Engelman K, Portnoy B, Lovenberg W. A sensitive and specific double isotope derivative method for the determination of catecholamines in biological specimens. Am J Med Sci 255: 259-268, 1968.
16. Esler MD, Nestel PJ. Sympathetic responsiveness to head-up tilt in essential hypertension. Clin Sci 44: 213-226, 1973.
17. Esler M, Jennings G, Korner P, Willett I, Dudley F, Hasking G, Anderson W, Lambert G. The assessment of human sympathetic nervous system activity from measurements of norepinephrine turnover. Hypertension 11: 3-20, 1988.
18. Esler M, Lambert G, Jennings G. Regional norepinephrine turnover in human hypertension. Clin Exp Hypertens 11, Suppl 1: 75-89, 1989.
19. Esler M, Jennings G, Lambert G, Meredith I, Horne M, Eisenhofer G. Overflow of catecholamine neurotransmitters to the circulation: source, fate and functions. Physiol Rev 70: 963-985, 1990.
20. Esler M, Dudley F, Jennings G, Debinski H, Lambert G, Jones P, Crotty B, Colman J, Willett I. Increased sympathetic nervous system activity, and effects of its pharmacological inhibition, in alcoholic cirrhosis. Ann Intern Med 116: 446-455, 1992.
21. Esler M. Looking at the sympathetic nervous system as a primary source. In: Handbook of Hypertension: Hypertension Research in the Twentieth Century, edited by Zanchetti A, Robertson JIS, and Birkenhager WH. Amsterdam: Elsevier, 2004, p. 81-103.
22. Esler M, Eikelis N, Schlaich M, Lambert G, Alvarenga M, Dawood T, Kaye D, Barton D, Pier C, Guo L, Brenchley C, Jennings G, Lambert E. Chronic mental stress is a cause of essential hypertension: presence of biological markers of stress. Clin Exp Pharm Physiol 35: 498-502, 2008.
23. Friberg P, Meredith I, Jennings G, Lambert G, Fazio V, Esler M. Evidence of increased renal noradrenaline spillover rate during sodium restriction in man. Hypertension 16: 121-130, 1990.
24. Grassi G, Colombo M, Seravalle G, Spaziani D, Mancia G. Dissociation between muscle and skin sympathetic nerve activity in essential hypertension, obesity, and congestive heart failure. Hypertension 31: 64-67, 1998.
25. Grassi G, Dell'Oro R, Quarti-Trevano F, Scopelliti F, Seravalle G, Paleari F, Gamba PL, Mancia G. Neuroadrenergic and reflex abnormalities in patients with the metabolic syndrome. Diabetologia 48: 1359-1365, 2005.
26. Hagbarth KE, Vallbo AB. Pulse and respiratory grouping of sympathetic impulses in human muscle nerves. Acta Physiol Scand 74: 96-106, 1968.
27. Hollenberg NK, Adams DF, Solomon H, Chenitz WR, Burger BM, Abrams HL, Merrill JP. Renal vascular tone in essential and secondary hypertension; hemodynamic and angiographic responses to vasodilators. Medicine 54: 29-44, 1975.
28. Hollenberg NK, Williams GW, Adams DF. Essential hypertension: abnormal renal vascular and endocrine responses to a mild psychological stimulus. Hypertension 3: 11-17, 1981.
29. Huggett RJ, Burns J, MackIntosh AF, Mary DASG. Sympathetic neural activation in nondiabetic metabolic syndrome and its further augmentation by hypertension. Hypertension 44: 1-6, 2004.
30. Kaye D, Esler M, Kingwell B, Jennings G, McPherson G, Esmore D. Functional and neurochemical evidence for partial cardiac sympathetic reinnervation after cardiac transplantation in humans. Circulation 88: 1101-1109, 1993.
31. Kirch W, Hutt HJ, Planitz V. Pharmacodynamic action and pharmacokinetics of moxonidine after single oral administration in hypertensive patients. J Clin Pharmacol 30: 1088-1095, 1990.
32. Kopp UC, Cicha MZ, Smith LA. Dietary sodium loading increases arterial pressure in afferent renal-denervated rats. Hypertension 42: 968-973, 2003.
33. Kopp UC, Smith LA, DiBona GF. Renorenal reflexes: neural components of ipsilateral and contralateral renal responses. Am J Physiol Renal Physiol 249: F507-F517, 1985.
34. Kopp UC, Jones SY, DiBona GF. Afferent renal denervation impairs baroreflex control of efferent renal sympathetic nerve activity. Am J Physiol Regul Integr Comp Physiol 295: R1882-R1890, 2008.
35. Kottke FJ, Kubicek WG, Visscher MB. The production of arterial hypertension by chronic renal artery-nerve stimulation. Am J Physiol 145: 38-47, 1945.
36. Krum H, Schlaich MP, Whitbourn R, Sobotka P, Sadowski J, Bartus K, Kapelak B, Walton A, Sievert H, Thambar S, Abraham WT, Esler M. Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study. Lancet 373: 1275-1281, 2009.
37. Kubicek WG, Kottke FJ, Laker DJ, Visscher MB. Renal function during arterial hypertension produced by chronic splanchnic nerve stimulation in the dog. Am J Physiol 174: 397-400, 1953.
38. Lambert E, Straznicky N, Schlaich MP, Dawood T, Hotchkin E, Esler MD, Lambert GW. Differing patterns of sympathoexcitation in normal weight and obesity-related hypertension. Hypertension 50: 862-868, 2007.
39. Ligtenberg G, Blankestijn PJ, Oey PL, Klein IH, Dijkhorst-Oei LT, Boomsma F, Wieneke GH, van Huffelen AC, Koomans HA. Reduction of sympathetic hyperactivity by enalapril in patients with chronic renal failure. N Engl J Med 340: 1321-1328, 1999.
40. Liu L, Barajas L. The rat renal nerves during development. Anat Embryol 188: 345-361, 1993.
41. Macefield V, Wallin BG, Vallbo AB. The discharge behaviour of single vasoconstrictor motoneurones in human muscle nerves. J Physiol 481: 799-809, 1994.
42. Meredith IT, Esler MD, Cox HS, Lambert GW, Jennings GL, Eisenhofer G. Biochemical evidence of sympathetic denervation of the heart in pure autonomic failure. Clin Autonom Res 1: 187-194, 1991.
43. Meredith IT, Friberg P, Jennings GL, Dewar EM, Fazio VA, Lambert GW, Esler MD. Regular exercise lowers renal but not cardiac sympathetic activity in man. Hypertension 18: 575-582, 1991.
44. Muller J, Barajas L. Electron microscopic and histochemical evidence for a tubular innervation in the renal cortex of the monkey. J Ultrastruct Res 41: 533-549, 1972.
45. Plato CF, Osborn JL. Chronic renal neuroadrenergic hypertension is associated with increased renal norepinephrine sensitivity and volume contraction. Hypertension 28: 1034-1040, 1996.
46. Roman RJ, Cowley AW. Characterization of a new model for the study of pressure natriuresis in the rat. Am J Physiol Renal Physiol 248: F190-F198, 1985.
47. Rumantir MS, Vaz M, Jennings GL, Collier G, Kaye DM, Seals DR, Wiesner GH, Brunner-La Rocca HP, Esler MD. Neural mechanisms in human obesity-related hypertension. J Hypertens 17: 1125-1133, 1999.
48. Schlaich MP, Sobotka PA, Krum H, Lambert E, Esler MD. Renal sympathetic nerve ablation for the treatment of uncontrolled hypertension. N Engl J Med 361: 932-934, 2009.
49. Shibao C, Gamboa A, Diedrich A, Ertl AC, Chen KY, Byrne DW, Farley G, Paranjape SY, Davis SN, Bioggioni I. Autonomic contribution to blood pressure and metabolism in obesity. Hypertension 49: 27-33, 2007.
50. Smithwick RH, Bush RD, Kinsey D, Whitelaw GP. Hypertension and associated cardiovascular disease; comparison of male and female mortality rates and their influence on selection of therapy. J Am Med Assoc 160: 1023-1026, 1956.
51. Starling EH. The Chemical Control of the Body. Harvey Lectures 1907-1908. New York: Lippincott, 1909, p. 115-131.
52. Stella A, Zanchetti A. Functional role of renal afferents. Physiol Rev 71: 659-682, 1991.
53. Steptoe A, Willemsen G. The influence of job control on ambulatory blood pressure and perceived stress over the working day in men and women from the Whitehall II cohort. J Hypertens 22: 915-920, 2004.
54. Thorén P. Efferent renal nerve traffic in SHR. Clin Exp Hypertens 9, Suppl 1: 259-279, 1987.
55. Wofford MR, Anderson DC, Brown CA, Jones DW, Miller ME, Hall JE. Antihypertensive effect of α- and β-adrenergic blockade in obese and lean hypertensive subjects. Am J Hypertens 14: 694-698, 2002.
56. Ye S, Zhong H, Yanamadala V, Campese VM. Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity. Am J Hypertens 15: 717-724, 2002.
57. Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, Mc-Queen M, Budaj A, Pais P, Varigos J, Lisheng L, on behalf of the INTERHEART investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): a case-control study. Lancet 364: 937-952, 2004.