Exploring the vinylogous reactivity of cyclohexenylidene malononitriles: Switchable regioselectivity in the organocatalytic asymmetric addition to enals giving highly enantioenriched carbabicyclic structures

Journal of the American Chemical Society

Volumn 136, Issue 31, 2014, Pages 11107-11114

  Dell'Amico, Luca ^a,c   Rassu, Gloria ^b   Zambrano, Vincenzo ^b   Sartori, Andrea ^a   Curti, Claudio ^a   Battistini, Lucia ^a   Pelosi, Giorgio ^a   Casiraghi, Giovanni ^a   Zanardi, Franca ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b CNR   (Italy)

^c INSTITUTE OF CHEMICAL RESEARCH OF CATALONIA ICIQ   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ISOTOPES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ASYMMETRIC ADDITION; ASYMMETRIC REACTION; BICYCLO[2.2.2]OCTANE; CARBON ISOTOPES; CHEMICAL STIMULI; EXPERIMENTAL EVIDENCE; VINYLOGOUS REACTIVITIES;

CATALYSIS;

ALIPHATIC CARBOXYLIC ACID; CINNAMALDEHYDE DERIVATIVE; CYCLOHEXENE DERIVATIVE; MALONONITRILE; NITROPHENOL; ALDEHYDE; BICYCLO COMPOUND; CARBENE; CYCLOHEXENE; METHANE; NITRILE; SPIRO COMPOUND;

ARTICLE; ASYMMETRIC SYNTHESIS; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CATALYST; CHEMICAL STRUCTURE; CYCLIZATION; CYCLOADDITION; DIELS ALDER REACTION; ENANTIOSELECTIVITY; HYDROGEN BOND; MICHAEL ADDITION; NUCLEOPHILICITY; REACTION TIME; STEREOCHEMISTRY; X RAY DIFFRACTION; ANALOGS AND DERIVATIVES; CHEMISTRY; ENZYME SPECIFICITY; STEREOISOMERISM;

ALDEHYDES; BICYCLO COMPOUNDS; CATALYSIS; CYCLOADDITION REACTION; CYCLOHEXENES; METHANE; NITRILES; SPIRO COMPOUNDS; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 84905714897     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja5054576     Document Type: Article

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