메뉴 건너뛰기




Volumn 7, Issue 1, 2014, Pages 193-201

Dysregulation of the homeobox transcription factor gene HOXB13: Role in prostate cancer

Author keywords

HOXB13; Prostate cancer risk

Indexed keywords

ANDROGEN RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HOXB13 PROTEIN; PROTEIN VARIANT; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 84905669015     PISSN: None     EISSN: 11787066     Source Type: Journal    
DOI: 10.2147/PGPM.S38117     Document Type: Review
Times cited : (25)

References (77)
  • 2
    • 0028052231 scopus 로고
    • Studies of genetic factors in prostate cancer in a twin population
    • discussion 1487-1489
    • Grönberg H, Damber L, Damber JE. Studies of genetic factors in prostate cancer in a twin population. J Urol. 1994; 152(5 Pt 1): 1484-1487; discussion 1487-1489.
    • (1994) J Urol , vol.152 , Issue.5 PART 1 , pp. 1484-1487
    • Grönberg, H.1    Damber, L.2    Damber, J.E.3
  • 3
    • 0034644185 scopus 로고    scopus 로고
    • Environmental and heritable factors in the causation of cancer-analyses of cohorts of twins from Sweden, Denmark, and Finland
    • Lichtenstein P, Holm NV, Verkasalo PK, etal. Environmental and heritable factors in the causation of cancer-analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med. 2000; 343(2): 78-85.
    • (2000) N Engl J Med , vol.343 , Issue.2 , pp. 78-85
    • Lichtenstein, P.1    Holm, N.V.2    Verkasalo, P.K.3
  • 4
    • 0032730732 scopus 로고    scopus 로고
    • Genetic predisposition, environment and cancer incidence: A nationwide twin study in Finland, 1976-1995
    • Verkasalo PK, Kaprio J, Koskenvuo M, Pukkala E. Genetic predisposition, environment and cancer incidence: a nationwide twin study in Finland, 1976-1995. Int J Cancer. 1999; 83(6): 743-749.
    • (1999) Int J Cancer , vol.83 , Issue.6 , pp. 743-749
    • Verkasalo, P.K.1    Kaprio, J.2    Koskenvuo, M.3    Pukkala, E.4
  • 6
    • 0037499554 scopus 로고    scopus 로고
    • Oligogenic segregation analysis of hereditary prostate cancer pedigrees: Evidence for multiple loci affecting age at onset
    • Conlon EM, Goode EL, Gibbs M, etal. Oligogenic segregation analysis of hereditary prostate cancer pedigrees: evidence for multiple loci affecting age at onset. Int J Cancer. 2003; 105(5): 630-635.
    • (2003) Int J Cancer , vol.105 , Issue.5 , pp. 630-635
    • Conlon, E.M.1    Goode, E.L.2    Gibbs, M.3
  • 7
    • 0035987715 scopus 로고    scopus 로고
    • Segregation analysis of prostate cancer in 1, 719 white, African-American and Asian-American families in the United States and Canada
    • Gong G, Oakley-Girvan I, Wu AH, etal. Segregation analysis of prostate cancer in 1, 719 white, African-American and Asian-American families in the United States and Canada. Cancer Causes Control. 2002; 13(5): 471-482.
    • (2002) Cancer Causes Control , vol.13 , Issue.5 , pp. 471-482
    • Gong, G.1    Oakley-Girvan, I.2    Wu, A.H.3
  • 8
    • 1242281248 scopus 로고    scopus 로고
    • Segregation analysis of prostate cancer in Sweden: Support for dominant inheritance
    • Grönberg H, Damber L, Damber JE, Iselius L. Segregation analysis of prostate cancer in Sweden: support for dominant inheritance. Am J Epidemiol. 1997; 146(7): 552-557.
    • (1997) Am J Epidemiol , vol.146 , Issue.7 , pp. 552-557
    • Grönberg, H.1    Damber, L.2    Damber, J.E.3    Iselius, L.4
  • 9
    • 75649120390 scopus 로고    scopus 로고
    • Prostate cancer segregation analyses using 4390 families from UK and Australian population-based studies
    • MacInnis RJ, Antoniou AC, Eeles RA, etal. Prostate cancer segregation analyses using 4390 families from UK and Australian population-based studies. Genet Epidemiol. 2010; 34(1): 42-50.
    • (2010) Genet Epidemiol , vol.34 , Issue.1 , pp. 42-50
    • McInnis, R.J.1    Antoniou, A.C.2    Eeles, R.A.3
  • 10
    • 33947120644 scopus 로고    scopus 로고
    • Segregation analysis of 1, 546 prostate cancer families in Finland shows recessive inheritance
    • Pakkanen S, Baffoe-Bonnie AB, Matikainen MP, etal. Segregation analysis of 1, 546 prostate cancer families in Finland shows recessive inheritance. Hum Genet. 2007; 121(2): 257-267.
    • (2007) Hum Genet , vol.121 , Issue.2 , pp. 257-267
    • Pakkanen, S.1    Baffoe-Bonnie, A.B.2    Matikainen, M.P.3
  • 11
    • 0034927358 scopus 로고    scopus 로고
    • The genetic epidemiology of cancer: Interpreting family and twin studies and their implications for molecular genetic approaches
    • Risch N. The genetic epidemiology of cancer: interpreting family and twin studies and their implications for molecular genetic approaches. Cancer Epidemiol Biomarkers Prev. 2001; 10(7): 733-741.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , Issue.7 , pp. 733-741
    • Risch, N.1
  • 12
    • 0345688716 scopus 로고    scopus 로고
    • International Consortium for Prostate Cancer Genetics. Where are the prostate cancer genes?-A summary of eight genome wide searches
    • Easton DF, Schaid DJ, Whittemore AS, Isaacs WJ; International Consortium for Prostate Cancer Genetics. Where are the prostate cancer genes?-A summary of eight genome wide searches. Prostate. 2003; 57(4): 261-269.
    • (2003) Prostate , vol.57 , Issue.4 , pp. 261-269
    • Easton, D.F.1    Schaid, D.J.2    Whittemore, A.S.3    Isaacs, W.J.4
  • 13
    • 56249103144 scopus 로고    scopus 로고
    • Inherited susceptibility to common cancers
    • Foulkes WD. Inherited susceptibility to common cancers. N Engl J Med. 2008; 359(20): 2143-2153.
    • (2008) N Engl J Med , vol.359 , Issue.20 , pp. 2143-2153
    • Foulkes, W.D.1
  • 14
  • 15
    • 0035740243 scopus 로고    scopus 로고
    • Prostate cancer susceptibility genes: Many studies, many results, no answers
    • Nupponen NN, Carpten JD. Prostate cancer susceptibility genes: many studies, many results, no answers. Cancer Metastasis Rev. 2001; 20(3-4): 155-164.
    • (2001) Cancer Metastasis Rev , vol.20 , Issue.3-4 , pp. 155-164
    • Nupponen, N.N.1    Carpten, J.D.2
  • 17
    • 78649680825 scopus 로고    scopus 로고
    • Genetics of prostate cancer risk
    • Pomerantz MM, Freedman ML. Genetics of prostate cancer risk. Mt Sinai J Med. 2010; 77(6): 643-654.
    • (2010) Mt Sinai J Med , vol.77 , Issue.6 , pp. 643-654
    • Pomerantz, M.M.1    Freedman, M.L.2
  • 18
    • 0242332637 scopus 로고    scopus 로고
    • Inherited predisposition to prostate cancer
    • Verhage BA, Kiemeney LA. Inherited predisposition to prostate cancer. Eur J Epidemiol. 2003; 18(11): 1027-1036.
    • (2003) Eur J Epidemiol , vol.18 , Issue.11 , pp. 1027-1036
    • Verhage, B.A.1    Kiemeney, L.A.2
  • 19
    • 70349545839 scopus 로고    scopus 로고
    • UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators; PRACTICAL Consortium. Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
    • Eeles RA, Kote-Jarai Z, Al Olama AA, etal; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators; PRACTICAL Consortium. Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet. 2009; 41(10): 1116-1121.
    • (2009) Nat Genet , vol.41 , Issue.10 , pp. 1116-1121
    • Eeles, R.A.1    Kote-Jarai, Z.2    Al Olama, A.A.3
  • 20
    • 39749129053 scopus 로고    scopus 로고
    • UK Genetic Prostate Cancer Study Collaborators; British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators. Multiple newly identified loci associated with prostate cancer susceptibility
    • Eeles RA, Kote-Jarai Z, Giles GG, etal; UK Genetic Prostate Cancer Study Collaborators; British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators. Multiple newly identified loci associated with prostate cancer susceptibility. Nat Genet. 2008; 40(3): 316-321.
    • (2008) Nat Genet , vol.40 , Issue.3 , pp. 316-321
    • Eeles, R.A.1    Kote-Jarai, Z.2    Giles, G.G.3
  • 21
    • 84875739291 scopus 로고    scopus 로고
    • COGS-Cancer Research UK GWAS-ELLIPSE (part of GAME-ON) Initiative; Australian Prostate Cancer Bioresource
    • UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' of Oncology; UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators; PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
    • Eeles RA, Olama AA, Benlloch S, etal; COGS-Cancer Research UK GWAS-ELLIPSE (part of GAME-ON) Initiative; Australian Prostate Cancer Bioresource; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' of Oncology; UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators; PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet. 2013; 45(4): 385-391, 391e1.
    • (2013) Nat Genet , vol.45 , Issue.4
    • Eeles, R.A.1    Olama, A.A.2    Benlloch, S.3
  • 22
    • 54049139306 scopus 로고    scopus 로고
    • Multiple novel prostate cancer predisposition loci confirmed by an international study: The PRACTICAL Consortium
    • PRACTICAL Consortium
    • Kote-Jarai Z, Easton DF, Stanford JL, etal; PRACTICAL Consortium. Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium. Cancer Epidemiol Biomarkers Prev. 2008; 17(8): 2052-2061.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , Issue.8 , pp. 2052-2061
    • Kote-Jarai, Z.1    Easton, D.F.2    Stanford, J.L.3
  • 23
    • 79960924160 scopus 로고    scopus 로고
    • Seven prostate cancer loci identified by a multi-stage genome-wide association study
    • Kote-Jarai Z, Olama AA, Giles GG, etal. Seven prostate cancer loci identified by a multi-stage genome-wide association study. Nat Genet. 2011; 43(8): 785-791.
    • (2011) Nat Genet , vol.43 , Issue.8 , pp. 785-791
    • Kote-Jarai, Z.1    Olama, A.A.2    Giles, G.G.3
  • 24
    • 84878451270 scopus 로고    scopus 로고
    • COGS-CRUK GWAS-ELLIPSE (Part of GAME-ON) Initiative; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators; PRACTICAL Consortium. Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression
    • Kote-Jarai Z, Saunders EJ, Leongamornlert DA, etal; COGS-CRUK GWAS-ELLIPSE (Part of GAME-ON) Initiative; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators; PRACTICAL Consortium. Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression. Hum Mol Genet. 2013; 22(12): 2520-2528.
    • (2013) Hum Mol Genet , vol.22 , Issue.12 , pp. 2520-2528
    • Kote-Jarai, Z.1    Saunders, E.J.2    Leongamornlert, D.A.3
  • 25
    • 84856037428 scopus 로고    scopus 로고
    • International Consortium for Prostate Cancer Genetics. Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG
    • Lu L, Cancel-Tassin G, Valeri A, etal; International Consortium for Prostate Cancer Genetics. Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG. Prostate. 2012; 72(4): 410-426.
    • (2012) Prostate , vol.72 , Issue.4 , pp. 410-426
    • Lu, L.1    Cancel-Tassin, G.2    Valeri, A.3
  • 26
    • 84862748368 scopus 로고    scopus 로고
    • International Consortium for Prostate Cancer Genetics. Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: Evidence from the International Consortium for Prostate Cancer Genetics (ICPCG)
    • Jin G, Lu L, Cooney KA, etal; International Consortium for Prostate Cancer Genetics. Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG). Hum Genet. 2012; 131(7): 1095-1103.
    • (2012) Hum Genet , vol.131 , Issue.7 , pp. 1095-1103
    • Jin, G.1    Lu, L.2    Cooney, K.A.3
  • 27
    • 84894435613 scopus 로고    scopus 로고
    • International Consortium for Prostate Cancer Genetics. Association analysis of 9, 560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease
    • Teerlink CC, Thibodeau SN, McDonnell SK, etal; International Consortium for Prostate Cancer Genetics. Association analysis of 9, 560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease. Hum Genet. 2014; 133(3): 347-356.
    • (2014) Hum Genet , vol.133 , Issue.3 , pp. 347-356
    • Teerlink, C.C.1    Thibodeau, S.N.2    McDonnell, S.K.3
  • 28
    • 33645736478 scopus 로고    scopus 로고
    • Genome-wide linkage scan for prostate cancer susceptibility genes in men with aggressive disease: Significant evidence for linkage at chromosome 15q12
    • Lange EM, Ho LA, Beebe-Dimmer JL, etal. Genome-wide linkage scan for prostate cancer susceptibility genes in men with aggressive disease: significant evidence for linkage at chromosome 15q12. Hum Genet. 2006; 119(4): 400-407.
    • (2006) Hum Genet , vol.119 , Issue.4 , pp. 400-407
    • Lange, E.M.1    Ho, L.A.2    Beebe-Dimmer, J.L.3
  • 29
    • 33750516605 scopus 로고    scopus 로고
    • Investigators of the International Consortium for Prostate Cancer Genetics. Pooled genome linkage scan of aggressive prostate cancer: Results from the International Consortium for Prostate Cancer Genetics
    • Schaid DJ, McDonnell SK, Zarfas KE, etal; Investigators of the International Consortium for Prostate Cancer Genetics. Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics. Hum Genet. 2006; 120(4): 471-485.
    • (2006) Hum Genet , vol.120 , Issue.4 , pp. 471-485
    • Schaid, D.J.1    McDonnell, S.K.2    Zarfas, K.E.3
  • 30
    • 0037369927 scopus 로고    scopus 로고
    • Confirmation of linkage of prostate cancer aggressiveness with chromosome 19q
    • Slager SL, Schaid DJ, Cunningham JM, etal. Confirmation of linkage of prostate cancer aggressiveness with chromosome 19q. Am J Hum Genet. 2003; 72(3): 759-762.
    • (2003) Am J Hum Genet , vol.72 , Issue.3 , pp. 759-762
    • Slager, S.L.1    Schaid, D.J.2    Cunningham, J.M.3
  • 31
    • 31944443013 scopus 로고    scopus 로고
    • Genome-wide linkage scan for prostate cancer aggressiveness loci using families from the University of Michigan Prostate Cancer Genetics Project
    • Slager SL, Zarfas KE, Brown WM, etal. Genome-wide linkage scan for prostate cancer aggressiveness loci using families from the University of Michigan Prostate Cancer Genetics Project. Prostate. 2006; 66(2): 173-179.
    • (2006) Prostate , vol.66 , Issue.2 , pp. 173-179
    • Slager, S.L.1    Zarfas, K.E.2    Brown, W.M.3
  • 32
    • 31944443917 scopus 로고    scopus 로고
    • Prostate cancer and genetic susceptibility: A genome scan incorporating disease aggressiveness
    • Stanford JL, McDonnell SK, Friedrichsen DM, etal. Prostate cancer and genetic susceptibility: a genome scan incorporating disease aggressiveness. Prostate. 2006; 66(3): 317-325.
    • (2006) Prostate , vol.66 , Issue.3 , pp. 317-325
    • Stanford, J.L.1    McDonnell, S.K.2    Friedrichsen, D.M.3
  • 33
    • 0035025453 scopus 로고    scopus 로고
    • Model-free linkage analysis with covariates confirms linkage of prostate cancer to chromosomes 1 and 4
    • Goddard KA, Witte JS, Suarez BK, Catalona WJ, Olson JM. Model-free linkage analysis with covariates confirms linkage of prostate cancer to chromosomes 1 and 4. Am J Hum Genet. 2001; 68(5): 1197-1206.
    • (2001) Am J Hum Genet , vol.68 , Issue.5 , pp. 1197-1206
    • Goddard, K.A.1    Witte, J.S.2    Suarez, B.K.3    Catalona, W.J.4    Olson, J.M.5
  • 34
    • 34250326618 scopus 로고    scopus 로고
    • Genome-wide linkage scan of prostate cancer Gleason score and confirmation of chromosome 19q
    • Schaid DJ, Stanford JL, McDonnell SK, etal. Genome-wide linkage scan of prostate cancer Gleason score and confirmation of chromosome 19q. Hum Genet. 2007; 121(6): 729-735.
    • (2007) Hum Genet , vol.121 , Issue.6 , pp. 729-735
    • Schaid, D.J.1    Stanford, J.L.2    McDonnell, S.K.3
  • 35
    • 0033940895 scopus 로고    scopus 로고
    • Genomewide scan for prostate cancer-aggressiveness loci
    • Witte JS, Goddard KA, Conti DV, etal. Genomewide scan for prostate cancer-aggressiveness loci. Am J Hum Genet. 2000; 67(1): 92-99.
    • (2000) Am J Hum Genet , vol.67 , Issue.1 , pp. 92-99
    • Witte, J.S.1    Goddard, K.A.2    Conti, D.V.3
  • 36
    • 84856176782 scopus 로고    scopus 로고
    • Germline mutations in HOXB13 and prostate-cancer risk
    • Ewing CM, Ray AM, Lange EM, etal. Germline mutations in HOXB13 and prostate-cancer risk. N Eng J Med. 2012; 366(2): 141-149.
    • (2012) N Eng J Med , vol.366 , Issue.2 , pp. 141-149
    • Ewing, C.M.1    Ray, A.M.2    Lange, E.M.3
  • 37
    • 0345374575 scopus 로고    scopus 로고
    • Genome-wide scan for prostate cancer susceptibility genes using families from the University of Michigan prostate cancer genetics project finds evidence for linkage on chromosome 17 near BRCA1
    • Lange EM, Gillanders EM, Davis CC, etal. Genome-wide scan for prostate cancer susceptibility genes using families from the University of Michigan prostate cancer genetics project finds evidence for linkage on chromosome 17 near BRCA1. Prostate. 2003; 57(4): 326-334.
    • (2003) Prostate , vol.57 , Issue.4 , pp. 326-334
    • Lange, E.M.1    Gillanders, E.M.2    Davis, C.C.3
  • 38
    • 65649119683 scopus 로고    scopus 로고
    • Evaluation of 8q24 and 17q risk loci and prostate cancer mortality
    • Penney KL, Salinas CA, Pomerantz M, etal. Evaluation of 8q24 and 17q risk loci and prostate cancer mortality. Clin Cancer Res. 2009; 15(9): 3223-3230.
    • (2009) Clin Cancer Res , vol.15 , Issue.9 , pp. 3223-3230
    • Penney, K.L.1    Salinas, C.A.2    Pomerantz, M.3
  • 39
    • 4344565052 scopus 로고    scopus 로고
    • Combined genome-wide scan for prostate cancer susceptibility genes
    • Gillanders EM, Xu J, Chang BL, etal. Combined genome-wide scan for prostate cancer susceptibility genes. J Natl Cancer Inst. 2004; 96(16): 1240-1247.
    • (2004) J Natl Cancer Inst , vol.96 , Issue.16 , pp. 1240-1247
    • Gillanders, E.M.1    Xu, J.2    Chang, B.L.3
  • 40
    • 22544431928 scopus 로고    scopus 로고
    • A combined genomewide linkage scan of 1, 233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics
    • ACTANE Consortium
    • Xu J, Dimitrov L, Chang BL, etal; ACTANE Consortium. A combined genomewide linkage scan of 1, 233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics. Am J Hum Genet. 2005; 77(2): 219-229.
    • (2005) Am J Hum Genet , vol.77 , Issue.2 , pp. 219-229
    • Xu, J.1    Dimitrov, L.2    Chang, B.L.3
  • 41
    • 33947283656 scopus 로고    scopus 로고
    • Fine-mapping the putative chromosome 17q21-22 prostate cancer susceptibility gene to a 10 cM region based on linkage analysis
    • Lange EM, Robbins CM, Gillanders EM, etal. Fine-mapping the putative chromosome 17q21-22 prostate cancer susceptibility gene to a 10 cM region based on linkage analysis. Hum Genet. 2007; 121(1): 49-55.
    • (2007) Hum Genet , vol.121 , Issue.1 , pp. 49-55
    • Lange, E.M.1    Robbins, C.M.2    Gillanders, E.M.3
  • 42
    • 0033386499 scopus 로고    scopus 로고
    • Linkage analysis of 153 prostate cancer families over a 30-cM region containing the putative susceptibility locus HPCX
    • Lange EM, Chen H, Brierley K, etal. Linkage analysis of 153 prostate cancer families over a 30-cM region containing the putative susceptibility locus HPCX. Clin Cancer Res. 1999; 5(12): 4013-4020.
    • (1999) Clin Cancer Res , vol.5 , Issue.12 , pp. 4013-4020
    • Lange, E.M.1    Chen, H.2    Brierley, K.3
  • 43
    • 84875790154 scopus 로고    scopus 로고
    • HOXB13 mutations in a population-based, case-control study of prostate cancer
    • Stott-Miller M, Karyadi DM, Smith T, etal. HOXB13 mutations in a population-based, case-control study of prostate cancer. Prostate. 2013; 73(6): 634-641.
    • (2013) Prostate , vol.73 , Issue.6 , pp. 634-641
    • Stott-Miller, M.1    Karyadi, D.M.2    Smith, T.3
  • 44
    • 84876547982 scopus 로고    scopus 로고
    • HOXB13 mutation and prostate cancer: Studies of siblings and aggressive disease
    • Witte JS, Mefford J, Plummer SJ, etal. HOXB13 mutation and prostate cancer: studies of siblings and aggressive disease. Cancer Epidemiol Biomarkers Prev. 2013; 22(4): 675-680.
    • (2013) Cancer Epidemiol Biomarkers Prev , vol.22 , Issue.4 , pp. 675-680
    • Witte, J.S.1    Mefford, J.2    Plummer, S.J.3
  • 46
    • 84872308743 scopus 로고    scopus 로고
    • International Consortium for Prostate Cancer Genetics. HOXB13 is a susceptibility gene for prostate cancer: Results from the International Consortium for Prostate Cancer Genetics (ICPCG)
    • Xu J, Lange EM, Lu L, etal; International Consortium for Prostate Cancer Genetics. HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG). Hum Genet. 2013; 132(1): 5-14.
    • (2013) Hum Genet , vol.132 , Issue.1 , pp. 5-14
    • Xu, J.1    Lange, E.M.2    Lu, L.3
  • 47
    • 84874042482 scopus 로고    scopus 로고
    • Population-based estimate of prostate cancer risk for carriers of the HOXB13 missense mutation G84E
    • MacInnis RJ, Severi G, Baglietto L, etal. Population-based estimate of prostate cancer risk for carriers of the HOXB13 missense mutation G84E. PLoS One. 2013; 8(2): e54727.
    • (2013) PLoS One , vol.8 , Issue.2
    • McInnis, R.J.1    Severi, G.2    Baglietto, L.3
  • 48
    • 84888839080 scopus 로고    scopus 로고
    • A population-based assessment of germline HOXB13 G84E mutation and prostate cancer risk
    • Karlsson R, Aly M, Clements M, etal. A population-based assessment of germline HOXB13 G84E mutation and prostate cancer risk. Eur Urol. 2014; 65(1): 169-176.
    • (2014) Eur Urol , vol.65 , Issue.1 , pp. 169-176
    • Karlsson, R.1    Aly, M.2    Clements, M.3
  • 49
    • 84873736252 scopus 로고    scopus 로고
    • Testing for the recurrent HOXB13 G84E germline mutation in men with clinical indications for prostate biopsy
    • Schroeck FR, Zuhlke KA, Siddiqui J, Siddiqui R, Cooney KA, Wei JT. Testing for the recurrent HOXB13 G84E germline mutation in men with clinical indications for prostate biopsy. J Urol. 2013; 189(3): 849-853.
    • (2013) J Urol , vol.189 , Issue.3 , pp. 849-853
    • Schroeck, F.R.1    Zuhlke, K.A.2    Siddiqui, J.3    Siddiqui, R.4    Cooney, K.A.5    Wei, J.T.6
  • 50
    • 84877248238 scopus 로고    scopus 로고
    • The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: Results from the REDUCE trial
    • Chen Z, Greenwood C, Isaacs WB, etal. The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trial. Carcinogenesis. 2013; 34(6): 1260-1264.
    • (2013) Carcinogenesis , vol.34 , Issue.6 , pp. 1260-1264
    • Chen, Z.1    Greenwood, C.2    Isaacs, W.B.3
  • 51
    • 84871617973 scopus 로고    scopus 로고
    • A novel germline mutation in HOXB13 is associated with prostate cancer risk in Chinese men
    • Lin X, Qu L, Chen Z, etal. A novel germline mutation in HOXB13 is associated with prostate cancer risk in Chinese men. Prostate. 2013; 73(2): 169-175.
    • (2013) Prostate , vol.73 , Issue.2 , pp. 169-175
    • Lin, X.1    Qu, L.2    Chen, Z.3
  • 52
    • 0026504525 scopus 로고
    • Homeobox genes and axial patterning
    • McGinnis W, Krumlauf R. Homeobox genes and axial patterning. Cell. 1992; 68(2): 283-302.
    • (1992) Cell , vol.68 , Issue.2 , pp. 283-302
    • McGinnis, W.1    Krumlauf, R.2
  • 53
    • 28844477866 scopus 로고    scopus 로고
    • The genesis and evolution of homeobox gene clusters
    • Garcia-Fernàndez J. The genesis and evolution of homeobox gene clusters. Nat Rev Genet. 2005; 6(12): 881-892.
    • (2005) Nat Rev Genet , vol.6 , Issue.12 , pp. 881-892
    • Garcia-Fernàndez, J.1
  • 54
    • 0029840724 scopus 로고
    • Hoxb-13: A new Hox gene in a distant region of the HOXB cluster maintains colinearity
    • Zeltser L, Desplan C, Heintz N. Hoxb-13: A new Hox gene in a distant region of the HOXB cluster maintains colinearity. Development. 1966; 122(8): 2475-2484.
    • (1966) Development , vol.122 , Issue.8 , pp. 2475-2484
    • Zeltser, L.1    Desplan, C.2    Heintz, N.3
  • 55
    • 0032710152 scopus 로고    scopus 로고
    • Androgen-independent expression of hoxb-13 in the mouse prostate
    • Sreenath T, Orosz A, Fujita K, Bieberich CJ. Androgen-independent expression of hoxb-13 in the mouse prostate. Prostate. 1999; 41(3): 203-207.
    • (1999) Prostate , vol.41 , Issue.3 , pp. 203-207
    • Sreenath, T.1    Orosz, A.2    Fujita, K.3    Bieberich, C.J.4
  • 56
    • 0038074197 scopus 로고    scopus 로고
    • Hoxb13 is required for normal differentiation and secretory function of the ventral prostate
    • Economides KD, Capecchi MR. Hoxb13 is required for normal differentiation and secretory function of the ventral prostate. Development. 2003; 130(10): 2061-2069.
    • (2003) Development , vol.130 , Issue.10 , pp. 2061-2069
    • Economides, K.D.1    Capecchi, M.R.2
  • 57
    • 10844266655 scopus 로고    scopus 로고
    • HOXB13 induces growth suppression of prostate cancer cells as a repressor of hormone-activated androgen receptor signaling
    • Jung C, Kim RS, Zhang HJ, Lee SJ, Jeng MH. HOXB13 induces growth suppression of prostate cancer cells as a repressor of hormone-activated androgen receptor signaling. Cancer Res. 2004; 64(24): 9185-9192.
    • (2004) Cancer Res , vol.64 , Issue.24 , pp. 9185-9192
    • Jung, C.1    Kim, R.S.2    Zhang, H.J.3    Lee, S.J.4    Jeng, M.H.5
  • 58
    • 70449123571 scopus 로고    scopus 로고
    • The homeodomain protein HOXB13 regulates the cellular response to androgens
    • Norris JD, Chang CY, Wittmann BM, etal. The homeodomain protein HOXB13 regulates the cellular response to androgens. Mol Cell. 2009; 36(3): 405-416.
    • (2009) Mol Cell , vol.36 , Issue.3 , pp. 405-416
    • Norris, J.D.1    Chang, C.Y.2    Wittmann, B.M.3
  • 59
    • 80052710019 scopus 로고    scopus 로고
    • HOXB13 is co-localized with androgen receptor to suppress androgen-stimulated prostate-specific antigen expression
    • Kim SD, Park RY, Kim YR, etal. HOXB13 is co-localized with androgen receptor to suppress androgen-stimulated prostate-specific antigen expression. Anat Cell Biol. 2010; 43(4): 284-293.
    • (2010) Anat Cell Biol , vol.43 , Issue.4 , pp. 284-293
    • Kim, S.D.1    Park, R.Y.2    Kim, Y.R.3
  • 60
    • 2342597203 scopus 로고    scopus 로고
    • HOXB13 homeodomain protein suppresses the growth of prostate cancer cells by the negative regulation of T-cell factor 4
    • Jung C, Kim RS, Lee SJ, Wang C, Jeng MH. HOXB13 homeodomain protein suppresses the growth of prostate cancer cells by the negative regulation of T-cell factor 4. Cancer Res. 2004; 64(9): 3046-3051.
    • (2004) Cancer Res , vol.64 , Issue.9 , pp. 3046-3051
    • Jung, C.1    Kim, R.S.2    Lee, S.J.3    Wang, C.4    Jeng, M.H.5
  • 61
    • 84891125047 scopus 로고    scopus 로고
    • HOXB13 contributes to G1/S and G2/M checkpoint controls in prostate
    • Hamid SM, Cicek S, Karamil S, etal. HOXB13 contributes to G1/S and G2/M checkpoint controls in prostate. Mol Cell Endocrinol. 2014; 383(1-2): 38-47.
    • (2014) Mol Cell Endocrinol , vol.383 , Issue.1-2 , pp. 38-47
    • Hamid, S.M.1    Cicek, S.2    Karamil, S.3
  • 62
    • 76249108098 scopus 로고    scopus 로고
    • A FOXA1-binding enhancer regulates Hoxb13 expression in the prostate gland
    • McMullin RP, Dobi A, Mutton LN, etal. A FOXA1-binding enhancer regulates Hoxb13 expression in the prostate gland. Proc Natl Acad Sci U S A. 2010; 107(1): 98-103.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.1 , pp. 98-103
    • McMullin, R.P.1    Dobi, A.2    Mutton, L.N.3
  • 63
    • 84899068774 scopus 로고    scopus 로고
    • G84E mutation in HOXB13 is firmly associated with prostate cancer risk: A meta-analysis
    • Huang H, Cai B. G84E mutation in HOXB13 is firmly associated with prostate cancer risk: a meta-analysis. Tumour Biol. 2014; 35(2): 1177-1182.
    • (2014) Tumour Biol , vol.35 , Issue.2 , pp. 1177-1182
    • Huang, H.1    Cai, B.2
  • 64
    • 33244474190 scopus 로고    scopus 로고
    • MCM7 amplification and overexpression are associated with prostate cancer progression
    • Ren B, Yu G, Tseng GC, etal. MCM7 amplification and overexpression are associated with prostate cancer progression. Oncogene. 2006; 25(7): 1090-1098.
    • (2006) Oncogene , vol.25 , Issue.7 , pp. 1090-1098
    • Ren, B.1    Yu, G.2    Tseng, G.C.3
  • 65
    • 84863731341 scopus 로고    scopus 로고
    • ATRA inhibits the proliferation of DU145 prostate cancer cells through reducing the methylation level of HOXB13 gene
    • Liu Z, Ren G, Shangguan C, etal. ATRA inhibits the proliferation of DU145 prostate cancer cells through reducing the methylation level of HOXB13 gene. PLoS One. 2012; 7(7): e40943.
    • (2012) PLoS One , vol.7 , Issue.7
    • Liu, Z.1    Ren, G.2    Shangguan, C.3
  • 66
    • 85019265113 scopus 로고    scopus 로고
    • HOXB13 downregulates intracellular zinc and increases NF-κB signaling to promote prostate cancer metastasis
    • Epub October 7
    • Kim YR, Kim IJ, Kang TW, etal. HOXB13 downregulates intracellular zinc and increases NF-κB signaling to promote prostate cancer metastasis. Oncogene. Epub October 7, 2013.
    • (2013) Oncogene
    • Kim, Y.R.1    Kim, I.J.2    Kang, T.W.3
  • 67
    • 20044385928 scopus 로고    scopus 로고
    • Expression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancer
    • Edwards S, Campbell C, Flohr P, etal. Expression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancer. Br J Cancer. 2005; 92(2): 376-381.
    • (2005) Br J Cancer , vol.92 , Issue.2 , pp. 376-381
    • Edwards, S.1    Campbell, C.2    Flohr, P.3
  • 68
    • 84863291665 scopus 로고    scopus 로고
    • Evaluation of HOXB13 as a molecular marker of recurrent prostate cancer
    • Jeong TO, Oh KJ, Xuan Nguyen NT, etal. Evaluation of HOXB13 as a molecular marker of recurrent prostate cancer. Mol Med Rep. 2012; 5(4): 901-904.
    • (2012) Mol Med Rep , vol.5 , Issue.4 , pp. 901-904
    • Jeong, T.O.1    Oh, K.J.2    Xuan Nguyen, N.T.3
  • 69
    • 22044455309 scopus 로고    scopus 로고
    • HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation
    • Jung C, Kim RS, Zhang H, etal. HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation. Br J Cancer. 2005; 92(12): 2233-2239.
    • (2005) Br J Cancer , vol.92 , Issue.12 , pp. 2233-2239
    • Jung, C.1    Kim, R.S.2    Zhang, H.3
  • 70
    • 33645025199 scopus 로고    scopus 로고
    • Epigenetic inactivation of the candidate tumor suppressor gene HOXB13 in human renal cell carcinoma
    • Okuda H, Toyota M, Ishida W, etal. Epigenetic inactivation of the candidate tumor suppressor gene HOXB13 in human renal cell carcinoma. Oncogene. 2006; 25(12): 1733-1742.
    • (2006) Oncogene , vol.25 , Issue.12 , pp. 1733-1742
    • Okuda, H.1    Toyota, M.2    Ishida, W.3
  • 71
    • 33744727226 scopus 로고    scopus 로고
    • Suppression of invasive characteristics by antisense introduction of overexpressed HOX genes in ovarian cancer cells
    • Yamashita T, Tazawa S, Yawei Z, etal. Suppression of invasive characteristics by antisense introduction of overexpressed HOX genes in ovarian cancer cells. Int J Oncol. 2006; 28(4): 931-938.
    • (2006) Int J Oncol , vol.28 , Issue.4 , pp. 931-938
    • Yamashita, T.1    Tazawa, S.2    Yawei, Z.3
  • 72
    • 36749045193 scopus 로고    scopus 로고
    • HOXB13 promotes ovarian cancer progression
    • Miao J, Wang Z, Provencher H, etal. HOXB13 promotes ovarian cancer progression. Proc Natl Acad Sci U S A. 2007; 104(43): 17093-17098.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.43 , pp. 17093-17098
    • Miao, J.1    Wang, Z.2    Provencher, H.3
  • 73
    • 33645360627 scopus 로고    scopus 로고
    • HOXB homeobox gene expression in cervical carcinoma
    • López R, Garrido E, Piña P, etal. HOXB homeobox gene expression in cervical carcinoma. Int J Gynecol Cancer. 2006; 16(1): 329-335.
    • (2006) Int J Gynecol Cancer , vol.16 , Issue.1 , pp. 329-335
    • López, R.1    Garrido, E.2    Piña, P.3
  • 74
    • 2942578063 scopus 로고    scopus 로고
    • A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
    • Ma XJ, Wang Z, Ryan PD, etal. A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell. 2004; 5(6): 607-616.
    • (2004) Cancer Cell , vol.5 , Issue.6 , pp. 607-616
    • Ma, X.J.1    Wang, Z.2    Ryan, P.D.3
  • 75
    • 37249009630 scopus 로고    scopus 로고
    • Exploring the two-gene ratio in breast cancer-independent roles for HOXB13 and IL17BR in prediction of clinical outcome
    • Jerevall PL, Brommesson S, Strand C, etal. Exploring the two-gene ratio in breast cancer-independent roles for HOXB13 and IL17BR in prediction of clinical outcome. Breast Cancer Res Treat. 2008; 107(2): 225-234.
    • (2008) Breast Cancer Res Treat , vol.107 , Issue.2 , pp. 225-234
    • Jerevall, P.L.1    Brommesson, S.2    Strand, C.3
  • 76
    • 84883474791 scopus 로고    scopus 로고
    • HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression
    • Shah N, Jin K, Cruz LA, etal. HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression. Cancer Res. 2013; 73(17): 5449-5458.
    • (2013) Cancer Res , vol.73 , Issue.17 , pp. 5449-5458
    • Shah, N.1    Jin, K.2    Cruz, L.A.3
  • 77
    • 11144327574 scopus 로고    scopus 로고
    • Range of HOX/TALE superclass associations and protein domain requirements for HOXA13: MEIS interaction
    • Williams TM, Williams ME, Innis JW. Range of HOX/TALE superclass associations and protein domain requirements for HOXA13: MEIS interaction. Dev Biol. 2005; 277(2): 457-471.
    • (2005) Dev Biol , vol.277 , Issue.2 , pp. 457-471
    • Williams, T.M.1    Williams, M.E.2    Innis, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.